Moshe Vardi | Profiles RNS

Moshe Vardi, MD

Adjunct Assistant Professor

Boston University School of Public Health

Biostatistics

MD, Tel Aviv University (TAU)
BSc, Tel Aviv University (TAU)

Websites

	School of Public Health Faculty
	Practice Update
	LinkedIn
	ResearchGate

Dr. Vardi is a Global Clinical Development Lead at Shire, previously a Clinical Research Medical Advisor at Novartis, the Medical Director at the Harvard Clinical Research Institute (HCRI), and an Assistant Professor (adj) at the Boston University School of Public Health (BUSPH). Dr. Vardi has a wide range of clinical, scientific and clinical research experience in diverse therapeutic indications, with involvement on both scientific and operational aspects. His current main focus is in the rare disease space, and prior to that in the cardio-metabolic space, with a footprint in design, execution, summary of results and submission to health agencies. His career in the field also includes a position as an Acting Director of an Internal Medicine unit, and board member of several national and international societies and professional working groups, and 15 years of experience in the Medical Device and Pharma industry. Dr. Vardi is a recipient of the European Federation of Internal Medicine Honorary Fellow award (2011). His research has been published in leading, peer-reviewed scientific journals, and has served as an Associate Editor for the European Journal of Internal Medicine.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Treangen TJ, Vardi MY. The long game of tenure. Nat Biotechnol. 2023 Oct; 41(10):1373-1374. PMID: 37626231

Farkas H, Reshef A, Caballero T, Ortega López MC, Kessel A, Vardi M, Hao J, Aberer W. Continued icatibant use across recurrent attacks in adolescents with hereditary angioedema. Pediatr Allergy Immunol. 2021 08; 32(6):1392-1396. PMID: 33851451; PMCID: PMC8453719; DOI: 10.1111/pai.13519;

Girolami A, Rolland C, Sexton D, Vardi M, Bernstein JA. Long-term safety outcomes of prekallikrein (Fletcher factor) deficiency: A systematic literature review of case reports. Allergy Asthma Proc. 2020 01 17; 41(1):10-18. PMID: 31888778

Fukunaga A, Morita E, Miyagi T, Eto K, Shimizu A, Kagami S, Yamamoto H, Vardi M, Tang Y, Wang Y, Hide M. [EFFICACY, PHARMACOKINETICS, PHARMACODYNAMICS, AND SAFETY OF INTRAVENOUS C1 INHIBITOR FOR LONG-TERM PROPHYLAXIS AND TREATMENT OF BREAKTHROUGH ATTACKS IN JAPANESE SUBJECTS WITH HEREDITARY ANGIOEDEMA: A PHASE 3 OPEN-LABEL STUDY]. Arerugi. 2020; 69(3):192-203. PMID: 32435020

Hide M, Fukunaga A, Maehara J, Eto K, Hao J, Vardi M, Nomoto Y. Efficacy, pharmacokinetics, and safety of icatibant for the treatment of Japanese patients with an acute attack of hereditary angioedema: A phase 3 open-label study. Allergol Int. 2020 Apr; 69(2):268-273. PMID: 31672405

Girolami A, Rolland C, Sexton D, Vardi M, Bernstein JA. Long-term safety outcomes of prekillikrein (Fletcher factor) deficiency: A systematic literature review of case reports. Allergy Asthma Proc. 2019 Sep 17. PMID: 31530337

Aygören-Pürsün E, Soteres DF, Nieto-Martinez SA, Christensen J, Jacobson KW, Moldovan D, Van Leerberghe A, Tang Y, Lu P, Vardi M, Schranz J, Martinez-Saguer I. A randomized trial of human C1 inhibitor prophylaxis in children with hereditary angioedema. Pediatr Allergy Immunol. 2019 08; 30(5):553-561. PMID: 30968444; PMCID: PMC6851661; DOI: 10.1111/pai.13060;

Lumry WR, Martinez-Saguer I, Yang WH, Bernstein JA, Jacobs J, Moldovan D, Riedl MA, Johnston DT, Li HH, Tang Y, Schranz J, Lu P, Vardi M, Farkas H. Fixed-Dose Subcutaneous C1-Inhibitor Liquid for Prophylactic Treatment of C1-INH-HAE: SAHARA Randomized Study. J Allergy Clin Immunol Pract. 2019 May - Jun; 7(5):1610-1618.e4. PMID: 30682573

Hide M, Fukunaga A, Maehara J, Eto K, Hao J, Vardi M, Nomoto Y. [EFFICACY, PHARMACOKINETICS, AND SAFETY OF ICATIBANT FOR THE TREATMENT OF JAPANESE PATIENTS WITH AN ACUTE ATTACK OF HEREDITARY ANGIOEDEMA: A PHASE 3 OPEN-LABEL STUDY]. Arerugi. 2018; 67(2):139-147. PMID: 29553114; DOI: 10.15036/arerugi.67.139;

Muady GF, Bitterman H, Laor A, Vardi M, Urin V, Ghanem-Zoubi N. Hemoglobin levels and blood transfusion in patients with sepsis in Internal Medicine Departments. BMC Infect Dis. 2016 10 13; 16(1):569. PMID: 27737630; PMCID: PMC5064795; DOI: 10.1186/s12879-016-1882-7;

Showing 10 of 58 results. Show More

Ghanem-Zoubi N, Bitterman H, Laor A, Yurin V, Vardi M. The accuracy of clinical prediction of prognosis for patients admitted with sepsis to internal medicine departments. Ann Med. 2015; 47(7):555-60. PMID: 26426517; DOI: 10.3109/07853890.2015.1089361;

Vardi M, Cryer BL, Cohen M, Lanas A, Schnitzer TJ, Lapuerta P, Goldsmith MA, Laine L, Doros G, Liu Y, McIntosh AI, Cannon CP, Bhatt DL. The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. Aliment Pharmacol Ther. 2015 Aug; 42(3):365-74.View Related Profiles.

Doros, Gheorghe
Vardi, Moshe

PMID: 26032114; PMCID: PMC4494867; DOI: 10.1111/apt.13260;

Chuang R, Hall BA, Benque D, Cook B, Ishtiaq S, Piterman N, Taylor A, Vardi M, Koschmieder S, Gottgens B, Fisher J. Drug target optimization in chronic myeloid leukemia using innovative computational platform. Sci Rep. 2015 Feb 03; 5:8190. PMID: 25644994; PMCID: PMC4650822; DOI: 10.1038/srep08190;

Perez R, Shaul C, Vardi M, Muhanna N, Kileny PR, Sichel JY. Multiple electrostimulation treatments to the promontory for tinnitus. Otol Neurotol. 2015 Feb; 36(2):366-72. PMID: 24691511; DOI: 10.1097/MAO.0000000000000309;

Veiner HL, Gorbatov R, Vardi M, Doros G, Miller-Lotan R, Zohar Y, Sabo E, Asleh R, Levy NS, Goldfarb LJ, Berk TA, Haas T, Shalom H, Suss-Toby E, Kam A, Kaplan M, Tamir R, Ziskind A, Levy AP. Pharmacogenomic interaction between the Haptoglobin genotype and vitamin E on atherosclerotic plaque progression and stability. Atherosclerosis. 2015 Mar; 239(1):232-9.View Related Profiles.

Doros, Gheorghe
Vardi, Moshe

PMID: 25618031; PMCID: PMC4331216; DOI: 10.1016/j.atherosclerosis.2015.01.008;

Vardi M, Lei L, Shangguan S, Doros G. Variability in freedom from loss of primary patency results in trials assessing stent implantation in the superficial femoral artery. J Invasive Cardiol. 2014 Nov; 26(11):614-7.View Related Profiles.

Doros, Gheorghe
Vardi, Moshe

PMID: 25364004

Elmariah S, Furlan AJ, Reisman M, Burke D, Vardi M, Wimmer NJ, Ling S, Chen X, Kent DM, Massaro J, Mauri L. Predictors of recurrent events in patients with cryptogenic stroke and patent foramen ovale within the CLOSURE I (Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale) trial. JACC Cardiovasc Interv. 2014 Aug; 7(8):913-20.View Related Profiles.

Massaro, Joseph
Vardi, Moshe
Elmariah, Sammy

PMID: 25147037; DOI: 10.1016/j.jcin.2014.01.170;

Vardi M, Perez J, Griffin PJ, Burke DA, Yeh RW, Cutlip DE. Usefulness of postmarket studies to evaluate long-term safety of coronary eluting stents (from the ENDEAVOR and PROTECT Programs). Am J Cardiol. 2014 Aug 15; 114(4):528-33. PMID: 24994546; DOI: 10.1016/j.amjcard.2014.05.028;

Vardi M, Debidda M, Bhatt DL, Mauri L, Cannon CP. Evolving antithrombotic strategies in patients with atrial fibrillation undergoing percutaneous coronary intervention: results from a survey among US cardiologists. Clin Cardiol. 2014 Feb; 37(2):103-7. PMID: 24672813; PMCID: PMC6649624; DOI: 10.1002/clc.22226;

Vardi M, Novack V, Pencina MJ, Doros G, Burke DA, Elmariah S, Cutlip DE, Mauri L, Yeh RW. Safety and efficacy metrics for primary nitinol stenting in femoropopliteal occlusive disease: a meta-analysis and critical examination of current methodologies. Catheter Cardiovasc Interv. 2014 May 1; 83(6):975-83.View Related Profiles.

Doros, Gheorghe
Pencina, Michael
Vardi, Moshe
Elmariah, Sammy

PMID: 23996913; DOI: 10.1002/ccd.25179;

Vardi M, Piazza G, Pencina MJ, Burke DA, Lei L, Goldhaber SZ, Cutlip DE. Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention. Clin Appl Thromb Hemost. 2014 Jul; 20(5):478-83.View Related Profiles.

Pencina, Michael
Vardi, Moshe

PMID: 24431382; DOI: 10.1177/1076029613517166;

Cranston M, Semple C, Duckitt R, Vardi M, Lindgren S, Davidson C, Palsson R. The practice of internal medicine in Europe: organisation, clinical conditions and procedures. Eur J Intern Med. 2013 Oct; 24(7):627-32. PMID: 24028929; DOI: 10.1016/j.ejim.2013.08.005;

Vardi M, Yeh RW, Herzog CA, Winkelmayer WC, Setoguchi S, Charytan DM. Strategies for postmarketing surveillance of drugs and devices in patients with ESRD undergoing dialysis. Clin J Am Soc Nephrol. 2013 Dec; 8(12):2213-20. PMID: 23970129; PMCID: PMC3848407; DOI: 10.2215/CJN.05130513;

Levy NS, Vardi M, Blum S, Miller-Lotan R, Afinbinder Y, Cleary PA, Paterson AD, Bharaj B, Snell-Bergeon JK, Rewers MJ, Lache O, Levy AP. An enzyme linked immunosorbent assay (ELISA) for the determination of the human haptoglobin phenotype. Clin Chem Lab Med. 2013 Aug; 51(8):1615-22. PMID: 23492570; PMCID: PMC3717392; DOI: 10.1515/cclm-2013-0018;

Vardi M, Burke DA, Bangalore S, Pencina MJ, Mauri L, Kandzari DE, Leon MB, Cutlip DE. Long-term efficacy and safety of Zotarolimus-eluting stent in patients with diabetes mellitus: pooled 5-year results from the ENDEAVOR III and IV trials. Catheter Cardiovasc Interv. 2013 Dec 1; 82(7):1031-8.View Related Profiles.

Pencina, Michael
Vardi, Moshe

PMID: 23737390; DOI: 10.1002/ccd.25045;

Vardi M, Levy NS, Levy AP. Vitamin E in the prevention of cardiovascular disease: the importance of proper patient selection. J Lipid Res. 2013 Sep; 54(9):2307-14. PMID: 23505320; PMCID: PMC3735930; DOI: 10.1194/jlr.R026641;

Vardi M, Ghanem-Zoubi NO, Zidan R, Yurin V, Bitterman H. Venous thromboembolism and the utility of the Padua Prediction Score in patients with sepsis admitted to internal medicine departments. J Thromb Haemost. 2013 Mar; 11(3):467-73. PMID: 23279085; DOI: 10.1111/jth.12108;

Vardi M, Ghanem-Zoubi NO, Bitterman H, Abo-Helo N, Yurin V, Weber G, Laor A. Sepsis in nonagenarians admitted to internal medicine departments: a comparative study of outcomes. QJM. 2013 Mar; 106(3):261-6. PMID: 23192596; DOI: 10.1093/qjmed/hcs221;

Shteinberg M, Segal-Trabelsy M, Adir Y, Laor A, Vardi M, Bitterman H. Clinical characteristics and outcomes of patients with clinically unsuspected pulmonary embolism versus patients with clinically suspected pulmonary embolism. Respiration. 2012; 84(6):492-500. PMID: 22986339; DOI: 10.1159/000342324;

Vardi M, Steinberg M, Haran M, Cohen S. Benefits versus risks of pharmacological prophylaxis to prevent symptomatic venous thromboembolism in unselected medical patients revisited. Meta-analysis of the medical literature. J Thromb Thrombolysis. 2012 Jul; 34(1):11-9. PMID: 22528330; DOI: 10.1007/s11239-012-0730-x;

Vardi M, Levy AP. Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin E therapy responsiveness in patients with diabetes? Curr Diab Rep. 2012 Jun; 12(3):274-9. PMID: 22427005; PMCID: PMC3590812; DOI: 10.1007/s11892-012-0265-8;

Vardi M, Blum S, Levy AP. Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med. 2012 Oct; 23(7):628-32. PMID: 22939808; PMCID: PMC3600118; DOI: 10.1016/j.ejim.2012.04.009;

Vardi M, Kochavi T, Denekamp Y, Bitterman H. Risk factors for urinary tract infection caused by Enterobacteriaceae with extended-spectrum beta-lactamase resistance in patients admitted to internal medicine departments. Isr Med Assoc J. 2012 Feb; 14(2):115-8. PMID: 22693794

Vardi M, Haran M. Venous thromboembolism prophylaxis of acutely ill hospitalized medical patients. Are we over-treating our patients? Eur J Intern Med. 2012 Apr; 23(3):231-5. PMID: 22385879; DOI: 10.1016/j.ejim.2011.11.006;

Vardi M, Dagna L, Haran M, Duckit R. Attitudes towards and practice of venous thromboembolism prevention in general internal medicine wards: a multinational survey from member countries of the European Federation of Internal Medicine. Thromb Res. 2012 May; 129(5):573-6. PMID: 21862111; DOI: 10.1016/j.thromres.2011.07.043;

Vardi M, Haran M. A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score: a rebuttal. J Thromb Haemost. 2011 Jul; 9(7):1437-8. PMID: 21501378; DOI: 10.1111/j.1538-7836.2011.04305.x;

Farbstein D, Blum S, Pollak M, Asaf R, Viener HL, Lache O, Asleh R, Miller-Lotan R, Barkay I, Star M, Schwartz A, Kalet-Littman S, Ozeri D, Vaya J, Tavori H, Vardi M, Laor A, Bucher SE, Anbinder Y, Moskovich D, Abbas N, Perry N, Levy Y, Levy AP. Vitamin E therapy results in a reduction in HDL function in individuals with diabetes and the haptoglobin 2-1 genotype. Atherosclerosis. 2011 Nov; 219(1):240-4. PMID: 21722898; PMCID: PMC3200506; DOI: 10.1016/j.atherosclerosis.2011.06.005;

Vardi M, Petersil N, Keysary A, Rzotkiewicz S, Laor A, Bitterman H. Immunological arousal during acute Q fever infection. Eur J Clin Microbiol Infect Dis. 2011 Dec; 30(12):1527-30. PMID: 21509477; DOI: 10.1007/s10096-011-1255-5;

Ghanem-Zoubi NO, Vardi M, Laor A, Weber G, Bitterman H. Assessment of disease-severity scoring systems for patients with sepsis in general internal medicine departments. Crit Care. 2011; 15(2):R95. PMID: 21401927; PMCID: PMC3219360; DOI: 10.1186/cc10102;

Nini A, Vardi M. Beware the glass-eyed patient with liver enlargement. Intern Med J. 2011 Feb; 41(2):210-1. PMID: 22747558; DOI: 10.1111/j.1445-5994.2010.02418.x;

Vardi M. Routine peripheral catheter replacement--does evidence support its use as a quality indicator? A commentary on Jull and Griffiths (2010). Int J Nurs Stud. 2011 Jun; 48(6):784-5. PMID: 21130453; DOI: 10.1016/j.ijnurstu.2010.10.012;

Duckitt R, Roger D, Palsson R, Runolfur P, Bosanska L, Lenka B, Dagna L, Lorenzo D, Durusu TM, Mine DT, Vardi M, Moshe V. Common diagnoses in internal medicine in Europe 2009: a pan-European, multi-centre survey. Eur J Intern Med. 2010 Oct; 21(5):449-52. PMID: 20816603; DOI: 10.1016/j.ejim.2010.06.012;

Blum S, Vardi M, Brown JB, Russell A, Milman U, Shapira C, Levy NS, Miller-Lotan R, Asleh R, Levy AP. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics. 2010 May; 11(5):675-84. PMID: 20415560; PMCID: PMC2880717; DOI: 10.2217/pgs.10.17;

Blum S, Vardi M, Levy NS, Miller-Lotan R, Levy AP. The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Atherosclerosis. 2010 Jul; 211(1):25-7. PMID: 20223458; PMCID: PMC2897919; DOI: 10.1016/j.atherosclerosis.2010.02.018;

Duckitt R, Tanriover MD, Bosanka L, Dagna L, Vardi M. The European Diploma of Internal Medicine--perspectives on the exam from across Europe. Eur J Intern Med. 2010 Feb; 21(1):46-7. PMID: 20122613; DOI: 10.1016/j.ejim.2009.10.005;

Vardi M, Laor A, Bitterman H. Activated partial thromboplastin time monitoring in patients receiving unfractionated heparin for venous thromboembolism in relation to clinical outcomes. Thromb Haemost. 2009 Nov; 102(5):879-86. PMID: 19888523; DOI: 10.1160/TH09-06-0404;

Vardi M, Zittan E, Bitterman H. Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism. Cochrane Database Syst Rev. 2009 Oct 07; (4):CD006771. PMID: 19821386; DOI: 10.1002/14651858.CD006771.pub2;

Lurie Y, Wasser SP, Taha M, Shehade H, Nijim J, Hoffmann Y, Basis F, Vardi M, Lavon O, Suaed S, Bisharat B, Bentur Y. Mushroom poisoning from species of genus Inocybe (fiber head mushroom): a case series with exact species identification. Clin Toxicol (Phila). 2009 Jul; 47(6):562-5. PMID: 19566380; DOI: 10.1080/15563650903008448;

Alavian SM, Izadi M, Zare AA, Lankarani MM, Assari S, Vardi MM. Survey of the level of anti-HBs antibody titer in vaccinated Iranian general dentists. Spec Care Dentist. 2008 Nov-Dec; 28(6):265-70. PMID: 19068068; DOI: 10.1111/j.1754-4505.2008.00052.x;

Vardi M, Jacobson E, Nini A, Bitterman H. Intermediate acting versus long acting insulin for type 1 diabetes mellitus. Cochrane Database Syst Rev. 2008 Jul 16; (3):CD006297. PMID: 18646147; PMCID: PMC6486116; DOI: 10.1002/14651858.CD006297.pub2;

Vardi M, Nini A. Near-infrared spectroscopy for evaluation of peripheral vascular disease. A systematic review of literature. Eur J Vasc Endovasc Surg. 2008 Jan; 35(1):68-74. PMID: 17919945; DOI: 10.1016/j.ejvs.2007.07.015;

Vardi M, Dori G, Bitterman H. Large-bore thoracentesis - A case report of a fatal consequence. Eur J Intern Med. 2007 Sep; 18(5):443-4. PMID: 17693238; DOI: 10.1016/j.ejim.2007.05.003;

Vardi M, Nini A. Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus. Cochrane Database Syst Rev. 2007 Jan 24; (1):CD002187. PMID: 17253475; PMCID: PMC6718223; DOI: 10.1002/14651858.CD002187.pub3;

Nesher N, Frolkis I, Vardi M, Sheinberg N, Bakir I, Caselman F, Pevni D, Ben-Gal Y, Sharony R, Bolotin G, Loberman D, Uretzky G, Weinbroum AA. Higher levels of serum cytokines and myocardial tissue markers during on-pump versus off-pump coronary artery bypass surgery. J Card Surg. 2006 Jul-Aug; 21(4):395-402. PMID: 16846420; DOI: 10.1111/j.1540-8191.2006.00272.x;

Raif J, Vardi M, Nahlieli O, Gannot I. An Er:YAG laser endoscopic fiber delivery system for lithotripsy of salivary stones. Lasers Surg Med. 2006 Jul; 38(6):580-7. PMID: 16705704; DOI: 10.1002/lsm.20344;

Nesher N, Uretzky G, Insler S, Nataf P, Frolkis I, Pineau E, Cantoni E, Bolotin G, Vardi M, Pevni D, Lev-Ran O, Sharony R, Weinbroum AA. Thermo-wrap technology preserves normothermia better than routine thermal care in patients undergoing off-pump coronary artery bypass and is associated with lower immune response and lesser myocardial damage. J Thorac Cardiovasc Surg. 2005 Jun; 129(6):1371-8. PMID: 15942580; DOI: 10.1016/j.jtcvs.2004.08.021;

Vakil E, Blachstein H, Rochberg J, Vardi M. Characterization of memory impairment following closed-head injury in children using the Rey Auditory Verbal Learning Test (AVLT). Child Neuropsychol. 2004 Jun; 10(2):57-66. PMID: 15590485; DOI: 10.1080/09297040490911078;

Skomorovski K, Harpak H, Ianovski A, Vardi M, Visser TP, Hartong SC, van Vliet HH, Wagemaker G, Agur Z. New TPO treatment schedules of increased safety and efficacy: pre-clinical validation of a thrombopoiesis simulation model. Br J Haematol. 2003 Nov; 123(4):683-91. PMID: 14616973

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 58 publications over 19 distinct years, with a maximum of 7 publications in 2011