Michael O'Brien | Profiles RNS

Michael J. O'Brien, MD, MPH

Emeritus Professor

Boston University Chobanian & Avedisian School of Medicine

Pathology & Laboratory Medicine

Anatomic Pathology

MBBCh, National University of Ireland
MPH, Harvard University
BSc, National University of Ireland

Websites

	Pathology & Laboratory Medicine Faculty
	Google Scholar

ORCID : 0000-0003-1124-3537

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Meester RGS, Lansdorp-Vogelaar I, Winawer SJ, Church TR, Allen JI, Feld AD, Mills G, Jordan PA, Corley DA, Doubeni CA, Hahn AI, Lobaugh SM, Fleisher M, O'Brien MJ, Zauber AG. Projected Colorectal Cancer Incidence and Mortality Based on Observed Adherence to Colonoscopy and Sequential Stool-Based Screening. Am J Gastroenterol. 2024 Jul 01; 119(7):1392-1401. PMID: 38318949; PMCID: PMC11222052; DOI: 10.14309/ajg.0000000000002693;

Zauber AG, Winawer SJ, O'Brien MJ, Mills GM, Allen JI, Feld AD, Jordan PA, Fleisher M, Orlow I, Meester RGS, Lansdorp-Vogelaar I, Rutter CM, Knudsen AB, Mandelson M, Shaukat A, Mendelsohn RB, Hahn AI, Lobaugh SM, Soto Palmer B, Serrano V, Kumar JR, Fischer SE, Chen JC, Bayuga-Miller S, Kuk D, O'Connell K, Church TR. Randomized Trial of Facilitated Adherence to Screening Colonoscopy vs Sequential Fecal-Based Blood Test. Gastroenterology. 2023 Jul; 165(1):252-266. PMID: 36948424; PMCID: PMC10330012; DOI: 10.1053/j.gastro.2023.03.206;

Zauber AG, Winawer SJ, O'Brien MJ, Mills GM, Allen JI, Feld AD, Jordan PA, Fleisher M, Orlow I, Meester RGS, Lansdorp-Vogelaar I, Rutter CM, Knudsen AB, Mandelson M, Shaukat A, Mendelsohn RB, Hahn AI, Lobaugh SM, Palmer BS, Serrano V, Kumar JR, Fischer SE, Chen JC, Bayuga-Miller S, Kuk D, O'Connell K, Church TR. Randomized Trial of Facilitated Adherence to Screening-Colonoscopy Versus Sequential Fecal-Based Blood Test. Gastroenterology. 2023 Mar 20. PMID: 36948424; PMCID: PMC10330012; DOI: 10.1053/j.gastro.2023.03.206;

Winawer SJ, Zauber AG, O'Brien MJ, Geenen J, Waye JD. The National Polyp Study at 40: challenges then and now. Gastrointest Endosc. 2021 03; 93(3):720-726. PMID: 33010298; PMCID: PMC7887080; DOI: 10.1016/j.gie.2020.09.044;

Drew DA, Mo A, Grady JJ, Stevens RG, Levine JB, Brenner BM, Anderson JC, Forouhar F, O'Brien MJ, Devers TJ, Rosenberg DW. Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression. Mol Cancer Res. 2018 03; 16(3):486-495. PMID: 29222172; PMCID: PMC5835173; DOI: 10.1158/1541-7786.MCR-17-0380;

Ho JD, Bhawan J, O'Brien MJ, Goldberg LJ. Cutaneous involvement in luteinized thecomas with sclerosing peritonitis (LTSP)-A new finding in a rare syndrome. J Cutan Pathol. 2017 Oct; 44(10):898-902.View Related Profiles.

Bhawan, Jag
Goldberg, Lynne
O'Brien, Michael

PMID: 28628256

Mendelsohn RB, Winawer SJ, Jammula A, Mills G, Jordan P, O'Brien MJ, Close GM, Dorfman M, Church TR, Mandelson MT, Allen J, Feld A, Kauff ND, Morgan GA, Kumar JMR, Serrano V, Bayuga-Miller S, Fischer SE, Kuk D, Zauber AG. Adenoma Prevalence in Blacks and Whites Having Equal Adherence To Screening Colonoscopy: The National Colonoscopy Study. Clin Gastroenterol Hepatol. 2017 09; 15(9):1469-1470. PMID: 28419856; PMCID: PMC5565703; DOI: 10.1016/j.cgh.2017.04.014;

Louis DN, O'Brien MJ, Young RH. The flowering of pathology as a medical discipline in Boston, 1892-c.1950: W.T. Councilman, FB Mallory, JH Wright, SB Wolbach and their descendants. Mod Pathol. 2016 Sep; 29(9):944-61. PMID: 27312063; DOI: 10.1038/modpathol.2016.91;

Herrera VL, Colby AH, Tan GA, Moran AM, O'Brien MJ, Colson YL, Ruiz-Opazo N, Grinstaff MW. Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis. Nanomedicine (Lond). 2016 May; 11(9):1001-15.View Related Profiles.

Colby, Aaron
Grinstaff, Mark
O'Brien, Michael
Ruiz-Opazo, Nelson
Herrera, Victoria

PMID: 27078118; PMCID: PMC4910944; DOI: 10.2217/nnm-2015-0023;

Shapiro MC, Wong B, O'Brien MJ, Salama A. Mandibular Destruction Secondary to Invasion by Carcinoma Cuniculatum. J Oral Maxillofac Surg. 2015 Dec; 73(12):2343-51.View Related Profiles.

Salama, Andrew
O'Brien, Michael

PMID: 26072180; DOI: 10.1016/j.joms.2015.05.034;

Showing 10 of 166 results. Show More

Schroy PC, Wong JB, O'Brien MJ, Chen CA, Griffith JL. A Risk Prediction Index for Advanced Colorectal Neoplasia at Screening Colonoscopy. Am J Gastroenterol. 2015 Jul; 110(7):1062-71.View Related Profiles.

O'Brien, Michael
Schroy, Paul

PMID: 26010311; PMCID: PMC4705553; DOI: 10.1038/ajg.2015.146;

Yu H, Buch K, Li B, O'Brien M, Soto J, Jara H, Anderson SW. Utility of texture analysis for quantifying hepatic fibrosis on proton density MRI. J Magn Reson Imaging. 2015 Nov; 42(5):1259-65.View Related Profiles.

Li, Baojun
Jara, Hernan
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 26477447; DOI: 10.1002/jmri.24898;

Shaukat A, Church TR, Shanley R, Kauff ND, O'Brien MJ, Mills GM, Jordan PA, Allen JA, Kim A, Feld AD, Zauber AG, Winawer SJ. Development and validation of a clinical score for predicting risk of adenoma at screening colonoscopy. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):913-20. PMID: 25800242; PMCID: PMC4452431; DOI: 10.1158/1055-9965.EPI-14-1321;

O'Brien MJ, Zhao Q, Yang S. Colorectal serrated pathway cancers and precursors. Histopathology. 2015 Jan; 66(1):49-65.View Related Profiles.

O'Brien, Michael
Zhao, Qing
Yang, Shi

PMID: 25263173; DOI: 10.1111/his.12564;

Qazi TM, O'Brien MJ, Farraye FA, Gould RW, Chen CA, Schroy PC. Epidemiology of goblet cell and microvesicular hyperplastic polyps. Am J Gastroenterol. 2014 Dec; 109(12):1922-32.View Related Profiles.

Farraye, Francis
O'Brien, Michael
Schroy, Paul
Gould, Ryan
Qazi, Taha

PMID: 25350766; DOI: 10.1038/ajg.2014.325;

Rodriguez-Diaz E, Huang Q, Cerda SR, O'Brien MJ, Bigio IJ, Singh SK. Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy. Gastrointest Endosc. 2015 Mar; 81(3):539-47.View Related Profiles.

Rodriguez-Diaz, Eladio
Bigio, Irving
O'Brien, Michael
Cerda, Sandra
Singh, Satish

PMID: 25257128; PMCID: PMC5533077; DOI: 10.1016/j.gie.2014.07.012;

O'Brien MJ, Meehan WP. Evaluating the risks and benefits of participation in high-school football. Virtual Mentor. 2014 Jul 01; 16(7):526-33. PMID: 25013917; DOI: 10.1001/virtualmentor.2014.16.07.ecas1-1407;

Lochhead P, Chan AT, Giovannucci E, Fuchs CS, Wu K, Nishihara R, O'Brien M, Ogino S. Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions. Am J Gastroenterol. 2014 Aug; 109(8):1205-14. PMID: 24935274; PMCID: PMC4125459; DOI: 10.1038/ajg.2014.153;

Rodriguez-Diaz E, Atkinson C, Jepeal LI, Berg A, Huang CS, Cerda SR, O'Brien MJ, Bigio IJ, Farraye FA, Singh SK. Elastic scattering spectroscopy as an optical marker of inflammatory bowel disease activity and subtypes. Inflamm Bowel Dis. 2014 Jun; 20(6):1029-36.View Related Profiles.

Huang, Christopher
Rodriguez-Diaz, Eladio
Farraye, Francis
Bigio, Irving
O'Brien, Michael
Cerda, Sandra
Singh, Satish

PMID: 24798637; PMCID: PMC4858439; DOI: 10.1097/MIB.0000000000000058;

Drew DA, Devers TJ, O'Brien MJ, Horelik NA, Levine J, Rosenberg DW. HD chromoendoscopy coupled with DNA mass spectrometry profiling identifies somatic mutations in microdissected human proximal aberrant crypt foci. Mol Cancer Res. 2014 Jun; 12(6):823-9. PMID: 24651453; PMCID: PMC4058342; DOI: 10.1158/1541-7786.MCR-13-0624;

Deshpande A, Nelson D, Corless CL, Deshpande V, O'Brien MJ. Leiomyoma of the gastrointestinal tract with interstitial cells of Cajal: a mimic of gastrointestinal stromal tumor. Am J Surg Pathol. 2014 Jan; 38(1):72-7. PMID: 24145645; DOI: 10.1097/PAS.0b013e3182a0d134;

Anderson SW, Barry B, Soto J, Ozonoff A, O'Brien M, Jara H. Characterizing non-gaussian, high b-value diffusion in liver fibrosis: Stretched exponential and diffusional kurtosis modeling. J Magn Reson Imaging. 2014 Apr; 39(4):827-34.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 24259401; DOI: 10.1002/jmri.24234;

Hart R, McCarthy I, O'brien M, Bess S, Line B, Adjei OB, Burton D, Gupta M, Ames C, Deviren V, Kebaish K, Shaffrey C, Wood K, Hostin R. Identification of decision criteria for revision surgery among patients with proximal junctional failure after surgical treatment of spinal deformity. Spine (Phila Pa 1976). 2013 Sep 1; 38(19):E1223-7. PMID: 23778370; DOI: 10.1097/BRS.0b013e31829fedde;

Schroy PC, Coe A, Chen CA, O'Brien MJ, Heeren TC. Prevalence of advanced colorectal neoplasia in white and black patients undergoing screening colonoscopy in a safety-net hospital. Ann Intern Med. 2013 Jul 2; 159(1):13-20.View Related Profiles.

O'Brien, Michael
Schroy, Paul
Heeren, Timothy

PMID: 23817700; PMCID: PMC4218749; DOI: 10.7326/0003-4819-159-1-201307020-00004;

Drew DA, Devers T, Horelik N, Yang S, O'Brien M, Wu R, Rosenberg DW. Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions. Proteomics. 2013 May; 13(9):1428-36.View Related Profiles.

O'Brien, Michael
Yang, Shi

PMID: 23467982; PMCID: PMC3805251; DOI: 10.1002/pmic.201200430;

Bennett M, Tompkins H, Seymour B, O'Brien MJ, Farraye FA. Spontaneous colonic perforation in a patient with collagenous colitis. Gastroenterol Hepatol (N Y). 2013 Apr; 9(4):262-4.View Related Profiles.

Farraye, Francis
O'Brien, Michael

PMID: 24711775; PMCID: PMC3977649

Agarwal S, Stucchi AF, Dendrinos K, Cerda S, O'Brien MJ, Becker JM, Heeren T, Farraye FA. Is pyloric gland metaplasia in ileal pouch biopsies a marker for Crohn's disease? Dig Dis Sci. 2013 Oct; 58(10):2918-25.View Related Profiles.

Stucchi, Arthur
Farraye, Francis
O'Brien, Michael
Cerda, Sandra
Heeren, Timothy

PMID: 23543088; DOI: 10.1007/s10620-013-2655-4;

Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF. Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. J Crohns Colitis. 2013 Jun; 7(5):403-11.View Related Profiles.

Stucchi, Arthur
Farraye, Francis
O'Brien, Michael
Cerda, Sandra
Leeman, Susan

PMID: 22921465; PMCID: PMC5279899; DOI: 10.1016/j.crohns.2012.08.003;

Anderson SW, Barry B, Soto JA, Ozonoff A, O'Brien M, Jara H. Quantifying hepatic fibrosis using a biexponential model of diffusion weighted imaging in ex vivo liver specimens. Magn Reson Imaging. 2012 Dec; 30(10):1475-82.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 22921938; DOI: 10.1016/j.mri.2012.05.010;

Rex DK, Ahnen DJ, Baron JA, Batts KP, Burke CA, Burt RW, Goldblum JR, Guillem JG, Kahi CJ, Kalady MF, O'Brien MJ, Odze RD, Ogino S, Parry S, Snover DC, Torlakovic EE, Wise PE, Young J, Church J. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol. 2012 Sep; 107(9):1315-29; quiz 1314, 1330. PMID: 22710576; PMCID: PMC3629844; DOI: 10.1038/ajg.2012.161;

Scalera JE, Soto JA, Jara H, Ozonoff A, O'Brien M, Anderson SW. Multiexponential T(2) analyses in a murine model of hepatic fibrosis at 11.7 T MRI. NMR Biomed. 2013 Jan; 26(1):83-90.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Scalera, Jonathan
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 22674663; DOI: 10.1002/nbm.2822;

Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012 Feb 23; 366(8):687-96. PMID: 22356322; PMCID: PMC3322371; DOI: 10.1056/NEJMoa1100370;

Anderson SW, Jara H, Ozonoff A, O'Brien M, Hamilton JA, Soto JA. Effect of disease progression on liver apparent diffusion coefficient and T2 values in a murine model of hepatic fibrosis at 11.7 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):140-6.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Hamilton, James
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 21990020; DOI: 10.1002/jmri.22807;

Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF, Becker JM. Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17420-5.View Related Profiles.

Stucchi, Arthur
Farraye, Francis
O'Brien, Michael
Cerda, Sandra
Leeman, Susan

PMID: 21969570; PMCID: PMC3198340; DOI: 10.1073/pnas.1114275108;

Anderson SW, Soto JA, Milch HN, Ozonoff A, O'Brien M, Hamilton JA, Jara HJ. Effect of disease progression on liver apparent diffusion coefficient values in a murine model of NASH at 11.7 Tesla MRI. J Magn Reson Imaging. 2011 Apr; 33(4):882-8.View Related Profiles.

Ozonoff, Alexander
Jara, Hernan
Hamilton, James
Soto, Jorge
O'Brien, Michael
Anderson, Stephan

PMID: 21448953; DOI: 10.1002/jmri.22481;

Winawer SJ, Krabshuis J, Lambert R, O'Brien M, Fried M. Cascade colorectal cancer screening guidelines: a global conceptual model. J Clin Gastroenterol. 2011 Apr; 45(4):297-300. PMID: 21301355; DOI: 10.1097/MCG.0b013e3182098e07;

Rex DK, Kahi C, O'Brien M, Levin TR, Pohl H, Rastogi A, Burgart L, Imperiale T, Ladabaum U, Cohen J, Lieberman DA. The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps. Gastrointest Endosc. 2011 Mar; 73(3):419-22. PMID: 21353837; DOI: 10.1016/j.gie.2011.01.023;

Huang CS, Farraye FA, Yang S, O'Brien MJ. The clinical significance of serrated polyps. Am J Gastroenterol. 2011 Feb; 106(2):229-40; quiz 241.View Related Profiles.

Huang, Christopher
Farraye, Francis
O'Brien, Michael
Yang, Shi

PMID: 21045813; DOI: 10.1038/ajg.2010.429;

Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O'Brien MJ, Farraye FA. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol. 2010 Dec; 105(12):2656-64.View Related Profiles.

Huang, Christopher
Farraye, Francis
O'Brien, Michael
Cerda, Sandra
Yang, Shi

PMID: 20717107; DOI: 10.1038/ajg.2010.315;

Lambert R, Kudo SE, Vieth M, Allen JI, Fujii H, Fujii T, Kashida H, Matsuda T, Mori M, Saito H, Shimoda T, Tanaka S, Watanabe H, Sung JJ, Feld AD, Inadomi JM, O'Brien MJ, Lieberman DA, Ransohoff DF, Soetikno RM, Zauber A, Teixeira CR, Rey JF, Jaramillo E, Rubio CA, Van Gossum A, Jung M, Jass JR, Triadafilopoulos G. Pragmatic classification of superficial neoplastic colorectal lesions. Gastrointest Endosc. 2009 Dec; 70(6):1182-99. PMID: 19879563; DOI: 10.1016/j.gie.2009.09.015;

Khalid O, Radaideh S, Cummings OW, O'Brien MJ, Goldblum JR, Rex DK. Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001. World J Gastroenterol. 2009 Aug 14; 15(30):3767-70. PMID: 19673017; PMCID: PMC2726454; DOI: 10.3748/wjg.15.3767;

Lambert R, O’Brien MJ, Jaramillo E, Vieth M. The serrated pathway to colorectal cancer. World Gastroenterology News. 2009; 14(2):5-11.
Winawer SJ, O'Brien MJ . Management of Malignant Polyps. Chap 30, in Colonscopy, Principles and Practice,2nd Edition, Eds:Waye JD, Rex DK, Williams CB. Wiley-Blackwell. 2009; 401-412.

Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J. 2009 Apr; 23(4):1054-63.View Related Profiles.

Rogers, Adrianne
Blusztajn, Jan
O'Brien, Michael
Yang, Shi
Mellott, Tiffany

PMID: 19047067; PMCID: PMC2660648; DOI: 10.1096/fj.08-122168;

Kudo Se, Lambert R, Allen JI, Fujii H, Fujii T, Kashida H, Matsuda T, Mori M, Saito H, Shimoda T, Tanaka S, Watanabe H, Sung JJ, Feld AD, Inadomi JM, O'Brien MJ, Lieberman DA, Ransohoff DF, Soetikno RM, Triadafilopoulos G, Zauber A, Teixeira CR, Rey JF, Jaramillo E, Rubio CA, Van Gossum A, Jung M, Vieth M, Jass JR, Hurlstone PD. Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointest Endosc. 2008 Oct; 68(4 Suppl):S3-47. PMID: 18805238; DOI: 10.1016/j.gie.2008.07.052;

Kokkotou E, Espinoza DO, Torres D, Karagiannides I, Kosteletos S, Savidge T, O'Brien M, Pothoulakis C. Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice. Gut. 2009 Jan; 58(1):34-40. PMID: 18824554; PMCID: PMC3058236; DOI: 10.1136/gut.2008.155341;

Kokkotou E, Moss AC, Torres D, Karagiannides I, Cheifetz A, Liu S, O'Brien M, Maratos-Flier E, Pothoulakis C. Melanin-concentrating hormone as a mediator of intestinal inflammation. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10613-8.View Related Profiles.

Moss, Alan
O'Brien, Michael

PMID: 18650383; PMCID: PMC2492477; DOI: 10.1073/pnas.0804536105;

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP. Corticotropin-releasing hormone deficiency is associated with reduced local inflammation in a mouse model of experimental colitis. Endocrinology. 2008 Jul; 149(7):3403-9. PMID: 18403481; PMCID: PMC2453096; DOI: 10.1210/en.2007-1703;

Kokkotou E, Moss AC, Michos A, Espinoza D, Cloud JW, Mustafa N, O'Brien M, Pothoulakis C, Kelly CP. Comparative efficacies of rifaximin and vancomycin for treatment of Clostridium difficile-associated diarrhea and prevention of disease recurrence in hamsters. Antimicrob Agents Chemother. 2008 Mar; 52(3):1121-6.View Related Profiles.

Moss, Alan
O'Brien, Michael

PMID: 18195066; PMCID: PMC2258528; DOI: 10.1128/AAC.01143-07;

Huang CS, Farraye FA, O’Brien MJ. What is a Serrated Adenoma and What do I tell my patients in terms of follow-up?. Curbside Consultation of the Colon, 49 Clinical Questions, Ed Cash BD, Farraye FA. Slack Inc. 2008; 45-47.
Huang CS, Farraye FA, O’Brien MJ . What is Hyperplastic Polyposis?. Curbside Consultation of the Colon, 49 Clinical Questions, Ed Cash BD, Farraye FA. Slack Inc. 2008; 39-44.

O'Brien MJ. Hyperplastic and serrated polyps of the colorectum. Gastroenterol Clin North Am. 2007 Dec; 36(4):947-68, viii. PMID: 17996799

Glatz K, Pritt B, Glatz D, Hartmann A, O'Brien MJ, Blaszyk H. A multinational, internet-based assessment of observer variability in the diagnosis of serrated colorectal polyps. Am J Clin Pathol. 2007 Jun; 127(6):938-45. PMID: 17509991

Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y, O'Brien MJ. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res. 2007 Apr 15; 67(8):3551-4.View Related Profiles.

O'Brien, Michael
Yang, Shi

PMID: 17440063

Katchar K, Kelly CP, Keates S, O'brien MJ, Keates AC. MIP-3alpha neutralizing monoclonal antibody protects against TNBS-induced colonic injury and inflammation in mice. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1263-71. PMID: 17272517

Jass JR, O'Brien MJ, Riddell RH, Snover DC. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma. Hum Pathol. 2007 Apr; 38(4):537-545. PMID: 17270246

O'Brien MJ, Bloom A, LaBerge JM, Roberts JP, Rosenthal P, Kerlan RK. SIR 2006 Annual Meeting Film Panel Case: Budd-Chiari syndrome in a patient with Cogan syndrome. J Vasc Interv Radiol. 2006 Dec; 17(12):1881-3. PMID: 17185682

O'Brien MJ, Yang S, Mack C, Xu H, Huang CS, Mulcahy E, Amorosino M, Farraye FA. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006 Dec; 30(12):1491-501.View Related Profiles.

Huang, Christopher
Farraye, Francis
Xu, Huihong
O'Brien, Michael
Yang, Shi

PMID: 17122504

Jass JR, O'Brien MJ, Riddell RH, Snover DC. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma. Virchows Arch. 2007 Jan; 450(1):1-13. PMID: 17334800

Gay J, Kokkotou E, O'Brien M, Pothoulakis C, Karalis KP. Interleukin-6 genetic ablation protects from trinitrobenzene sulfonic acid-induced colitis in mice. Putative effect of antiinflammatory cytokines. Neuroimmunomodulation. 2006; 13(2):114-21. PMID: 17077645

Kokkotou E, Torres D, Moss AC, O'Brien M, Grigoriadis DE, Karalis K, Pothoulakis C. Corticotropin-releasing hormone receptor 2-deficient mice have reduced intestinal inflammatory responses. J Immunol. 2006 Sep 1; 177(5):3355-61.View Related Profiles.

Moss, Alan
O'Brien, Michael

PMID: 16920976

Stucchi A, Reed K, O'Brien M, Cerda S, Andrews C, Gower A, Bushell K, Amar S, Leeman S, Becker J. A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflamm Bowel Dis. 2006 Jul; 12(7):581-7.View Related Profiles.

Gower, Adam
Stucchi, Arthur
O'Brien, Michael
Amar, Salomon
Cerda, Sandra
Leeman, Susan

PMID: 16804395

Chen X, Kokkotou EG, Mustafa N, Bhaskar KR, Sougioultzis S, O'Brien M, Pothoulakis C, Kelly CP. Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis. J Biol Chem. 2006 Aug 25; 281(34):24449-54. PMID: 16816386

Winawer SJ, Zauber AG, Fletcher RH, Stillman JS, O'Brien MJ, Levin B, Smith RA, Lieberman DA, Burt RW, Levin TR, Bond JH, Brooks D, Byers T, Hyman N, Kirk L, Thorson A, Simmang C, Johnson D, Rex DK. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. Gastroenterology. 2006 May; 130(6):1872-85. PMID: 16697750

Rex DK, Kahi CJ, Levin B, Smith RA, Bond JH, Brooks D, Burt RW, Byers T, Fletcher RH, Hyman N, Johnson D, Kirk L, Lieberman DA, Levin TR, O'Brien MJ, Simmang C, Thorson AG, Winawer SJ. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2006 May; 130(6):1865-71. PMID: 16697749

Rex DK, Kahi CJ, Levin B, Smith RA, Bond JH, Brooks D, Burt RW, Byers T, Fletcher RH, Hyman N, Johnson D, Kirk L, Lieberman DA, Levin TR, O'Brien MJ, Simmang C, Thorson AG, Winawer SJ. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and US Multi-Society Task Force on Colorectal Cancer. CA Cancer J Clin. 2006 May-Jun; 56(3):160-7; quiz 185-6. PMID: 16737948

Winawer SJ, Zauber AG, Fletcher RH, Stillman JS, O'brien MJ, Levin B, Smith RA, Lieberman DA, Burt RW, Levin TR, Bond JH, Brooks D, Byers T, Hyman N, Kirk L, Thorson A, Simmang C, Johnson D, Rex DK. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. CA Cancer J Clin. 2006 May-Jun; 56(3):143-59; quiz 184-5. PMID: 16737947

Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C. Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):5207-12.View Related Profiles.

O'Brien, Michael
Leeman, Susan

PMID: 16549770; PMCID: PMC1458819; DOI: 10.1073/pnas.0600821103;

Yantiss RK, Farraye FA, O'Brien MJ, Fruin AB, Stucchi AF, Becker JM, Reddy SI, Odze RD. Prognostic significance of superficial fissuring ulceration in patients with severe "indeterminate" colitis. Am J Surg Pathol. 2006 Feb; 30(2):165-70.View Related Profiles.

Stucchi, Arthur
Farraye, Francis
O'Brien, Michael

PMID: 16434889

Nunes D, Fleming C, Offner G, O'Brien M, Tumilty S, Fix O, Heeren T, Koziel M, Graham C, Craven DE, Stuver S, Horsburgh CR. HIV infection does not affect the performance of noninvasive markers of fibrosis for the diagnosis of hepatitis C virus-related liver disease. J Acquir Immune Defic Syndr. 2005 Dec 15; 40(5):538-44.View Related Profiles.

Horsburgh, C.
Nunes, David
Offner, Gwynneth
O'Brien, Michael
Stuver, Sherri
Heeren, Timothy

PMID: 16284529

Reed KL, Fruin AB, Gower AC, Gonzales KD, Stucchi AF, Andry CD, O'Brien M, Becker JM. NF-kappaB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci. 2005 Dec; 50(12):2366-78.View Related Profiles.

Gower, Adam
Stucchi, Arthur
Andry, Christopher
O'Brien, Michael

PMID: 16416193

Rhee SH, Im E, Riegler M, Kokkotou E, O'brien M, Pothoulakis C. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13610-5. PMID: 16157881; PMCID: PMC1224619; DOI: 10.1073/pnas.0502174102;

Huang CS, O'brien MJ, Yang S, Farraye FA. Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway. Am J Gastroenterol. 2004 Nov; 99(11):2242-55.View Related Profiles.

Huang, Christopher
Farraye, Francis
O'Brien, Michael
Yang, Shi

PMID: 15555008

Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004 Nov; 28(11):1452-9.View Related Profiles.

Farraye, Francis
O'Brien, Michael
Yang, Shi

PMID: 15489648

O'brien MJ, Winawer SJ, Zauber AG, Bushey MT, Sternberg SS, Gottlieb LS, Bond JH, Waye JD, Schapiro M. Flat adenomas in the National Polyp Study: is there increased risk for high-grade dysplasia initially or during surveillance? Clin Gastroenterol Hepatol. 2004 Oct; 2(10):905-11. PMID: 15476154

Anton PM, O'Brien M, Kokkotou E, Eisenstein B, Michaelis A, Rothstein D, Paraschos S, Kelly CP, Pothoulakis C. Rifalazil treats and prevents relapse of clostridium difficile-associated diarrhea in hamsters. Antimicrob Agents Chemother. 2004 Oct; 48(10):3975-9. PMID: 15388461; PMCID: PMC521872

Yantiss RK, Sapp HL, Farraye FA, El-Zammar O, O'Brien MJ, Fruin AB, Stucchi AF, Brien TP, Becker JM, Odze RD. Histologic predictors of pouchitis in patients with chronic ulcerative colitis. Am J Surg Pathol. 2004 Aug; 28(8):999-1006.View Related Profiles.

Stucchi, Arthur
Farraye, Francis
O'Brien, Michael

PMID: 15252305

Anton PM, Gay J, Mykoniatis A, Pan A, O'Brien M, Brown D, Karalis K, Pothoulakis C. Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci U S A. 2004 Jun 1; 101(22):8503-8. PMID: 15159534; PMCID: PMC420423

O'Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, Amorosino M, Swan N. Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol. 2004 Apr; 28(4):423-34.View Related Profiles.

Farraye, Francis
O'Brien, Michael
Yang, Shi

PMID: 15087661

Pistey RW, O'Brien MJ. Digital Imaging...Ready for Prime Time. Laboratory Medicine. 2004; 35:87-91.

Savidge TC, Pan WH, Newman P, O'brien M, Anton PM, Pothoulakis C. Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine. Gastroenterology. 2003 Aug; 125(2):413-20. PMID: 12891543

Stucchi AF, Shebani KO, Leeman SE, Wang CC, Reed KL, Fruin AB, Gower AC, McClung JP, Andry CD, O'Brien MJ, Pothoulakis C, Becker JM. A neurokinin 1 receptor antagonist reduces an ongoing ileal pouch inflammation and the response to a subsequent inflammatory stimulus. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1259-67.View Related Profiles.

Gower, Adam
Stucchi, Arthur
Andry, Christopher
O'Brien, Michael
Leeman, Susan

PMID: 12893626

Fruin AB, El-Zammer O, Stucchi AF, O'Brien M, Becker JM. Colonic metaplasia in the ileal pouch is associated with inflammation and is not the result of long-term adaptation. J Gastrointest Surg. 2003 Feb; 7(2):246-53; discussion 253-4.View Related Profiles.

Stucchi, Arthur
O'Brien, Michael

PMID: 12600449

Winawer SJ, O'Brien MJ . Management of Malignant Polyps. In Colonoscopy: Principles and Practice. Waye JD, Rex DK, Williams CB, Ed. Blackwell, Inc. London,UK. 2003; 448-449.

Zauber AG, O'Brien MJ, Winawer SJ. On finding flat adenomas: is the search worth the gain? Gastroenterology. 2002 Mar; 122(3):839-40. PMID: 11878297

Tendler DA, Aboudola S, Zacks JF, O'Brien MJ, Kelly CP. Prolapsing mucosal polyps: an underrecognized form of colonic polyp--a clinicopathological study of 15 cases. Am J Gastroenterol. 2002 Feb; 97(2):370-6. PMID: 11866275

Patriquin L, Kassarjian A, Barish M, Casserley L, O'Brien M, Andry C, Eustace S. Postmortem whole-body magnetic resonance imaging as an adjunct to autopsy: preliminary clinical experience. J Magn Reson Imaging. 2001 Feb; 13(2):277-87.View Related Profiles.

Andry, Christopher
O'Brien, Michael

PMID: 11169835

Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, Shebani K, Moore F, O'Brien M, Becker JM. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1298-306.View Related Profiles.

Stucchi, Arthur
O'Brien, Michael
Leeman, Susan

PMID: 11093954

O'Brien MJ, Keating NM, Elderiny S, Cerda S, Keaveny AP, Afdhal NH, Nunes DP. An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C. Am J Clin Pathol. 2000 Nov; 114(5):712-8.View Related Profiles.

Nunes, David
O'Brien, Michael
Cerda, Sandra

PMID: 11068544

Shie JL, Chen ZY, O'Brien MJ, Pestell RG, Lee ME, Tseng CC. Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. Am J Physiol Gastrointest Liver Physiol. 2000 Oct; 279(4):G806-14. PMID: 11005769

Winawer SJ, Stewart ET, Zauber AG, Bond JH, Ansel H, Waye JD, Hall D, Hamlin JA, Schapiro M, O'Brien MJ, Sternberg SS, Gottlieb LS. A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group. N Engl J Med. 2000 Jun 15; 342(24):1766-72. PMID: 10852998

Mulligan NJ, Yang S, Andry C, Klein M, O'Brien MJ. The role of p21ras in pancreatic neoplasia and chronic pancreatitis. Hum Pathol. 1999 Jun; 30(6):602-10.View Related Profiles.

Andry, Christopher
O'Brien, Michael
Yang, Shi

PMID: 10374765

Mulligan NJ, de las Morenas A, Soto-Wright V, O'Brien MJ. Percentages of cervical cytologic diagnoses as a quality assurance method. Acta Cytol. 1998 Jul-Aug; 42(4):928-32.View Related Profiles.

De Las Morenas, Antonio
O'Brien, Michael
Soto-Wright, Valena

PMID: 9684579

Zacks JF, de las Morenas A, Beazley RM, O'Brien MJ. Fine-needle aspiration cytology diagnosis of colloid nodule versus follicular variant of papillary carcinoma of the thyroid. Diagn Cytopathol. 1998 Feb; 18(2):87-90.View Related Profiles.

De Las Morenas, Antonio
O'Brien, Michael
Beazley, Robert

PMID: 9484634

O'Brien MJ, Takahashi M, Brugal G, Christen H, Gahm T, Goodell RM, Karakitsos P, Knesel EA, Kobler T, Kyrkou KA, Labbe S, Long EL, Mango LJ, McGoogan E, Oberholzer M, Reith A, Winkler C. Digital imagery/telecytology. International Academy of Cytology Task Force summary. Diagnostic Cytology Towards the 21st Century: An International Expert Conference and Tutorial. Acta Cytol. 1998 Jan-Feb; 42(1):148-64. PMID: 9479334

Afdhal NH, Keaveny AP, Cohen SB, Nunes DP, Maldonado N, O'Brien M, Stone PJ. Urinary assays for desmosine and hydroxylysylpyridinoline in the detection of cirrhosis. J Hepatol. 1997 Dec; 27(6):993-1002.View Related Profiles.

Nunes, David
O'Brien, Michael
Stone, Phillip

PMID: 9453424

Fogt F, Nikulasson ST, Holden JA, Alder SA, Hallgrimsson J, Jessup MJ, O'Brien MJ, Lavin PT, Goldman H. Topoisomerase II alpha expression in normal, inflammatory, and neoplastic conditions of the gastric and colonic mucosa. Mod Pathol. 1997 Apr; 10(4):296-302. PMID: 9110290

Mac Mathuna P, Siegenberg D, Gibbons D, Gorin D, O'Brien M, Afdhal NA, Chuttani R. The acute and long-term effect of balloon sphincteroplasty on papillary structure in pigs. Gastrointest Endosc. 1996 Dec; 44(6):650-5. PMID: 8979052

O'Brien MJ, Sotnikov AV. Digital imaging in anatomic pathology. Am J Clin Pathol. 1996 Oct; 106(4 Suppl 1):S25-32. PMID: 8853053

O'Brien MJ, Gibbons D. The adenoma-carcinoma sequence in colorectal neoplasia. Surg Oncol Clin N Am. 1996 Jul; 5(3):513-30. PMID: 8829316

Celen O, O'Brien MJ, Melby JC, Beazley RM. Factors influencing outcome of surgery for primary aldosteronism. Arch Surg. 1996 Jun; 131(6):646-50.View Related Profiles.

O'Brien, Michael
Beazley, Robert

PMID: 8645073

Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, Shike M, Swaroop SV, Levin B, Frühmorgen P, Lynch HT. [Prevention of colorectal carcinoma. Current WHO guidelines for early detection of colorectal carcinoma. World Health Organization Collaborating Center for the Prevention of Colorectal Cancer]. Leber Magen Darm. 1996 May; 26(3):139-40, 143. PMID: 8709827

Winawer SJ, Zauber AG, Gerdes H, O'Brien MJ, Gottlieb LS, Sternberg SS, Bond JH, Waye JD, Schapiro M, Panish JF, et al. Risk of colorectal cancer in the families of patients with adenomatous polyps. National Polyp Study Workgroup. N Engl J Med. 1996 Jan 11; 334(2):82-7. PMID: 8531963

Association of Directors of Anatomic Pathology. Recommendations for Reporting of Resected Large Intestinal Carcinomas. Hum. Pathol. 1996; 27:5-8.

Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, et al. Guidelines for the prevention of colorectal cancer: update based on new data. World Health Organization Collaborating Center for the Prevention of Colorectal Cancer. Z Gastroenterol. 1995 Sep; 33(9):574-6. PMID: 8525666

Schroy PC, Brown-Shimer S, Kim K, Johnson KA, Murnane MJ, Yang S, O'Brien MJ, Carney WP, Kupchik HZ. Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay. Cancer. 1995 Jul 15; 76(2):201-9.View Related Profiles.

Murnane, Mary
O'Brien, Michael
Schroy, Paul
Yang, Shi

PMID: 8625092

Winawer SJ, St John DJ, Bond JH, Rozen P, Burt RW, Waye JD, Kronborg O, O'Brien MJ, Bishop DT, Kurtz RC, et al. Prevention of colorectal cancer: guidelines based on new data. WHO Collaborating Center for the Prevention of Colorectal Cancer. Bull World Health Organ. 1995; 73(1):7-10. PMID: 7704928; PMCID: PMC2486580

O’Brien MJ . Colorectal Polyps in Cancer of the Colon, Rectum and Anus. Eds. Cohen A, Winawer S. McGraw-Hill,. 1994.
Waye JD, O’Brien MJ . Cancer in Polyps. Cancer of the Colon, Rectum and Anus. Eds. Cohen A, Winawer S. McGraw-Hill. 1994.

Winawer SJ, Zauber AG, Ho MN, O'Brien MJ, Gottlieb LS, Sternberg SS, Waye JD, Schapiro M, Bond JH, Panish JF, et al. Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med. 1993 Dec 30; 329(27):1977-81. PMID: 8247072

Winawer SJ, Zauber AG, Ho MN, O'Brien MJ, Gottlieb LS, Sternberg SS, Stewart ET, Bond JH, Schapiro M, Panish JF, et al. The National Polyp Study. Eur J Cancer Prev. 1993 Jun; 2 Suppl 2:83-7. PMID: 8364377

Sheahan K, O'Keane JC, Abramowitz A, Carlson JA, Burke B, Gottlieb LS, O'Brien MJ. Metastatic adenocarcinoma of an unknown primary site. A comparison of the relative contributions of morphology, minimal essential clinical data and CEA immunostaining status. Am J Clin Pathol. 1993 Jun; 99(6):729-35.View Related Profiles.

Sheahan, Kieran
O'Brien, Michael

PMID: 8322709

Kline TJ, De las Morenas T, O'Brien M, Smith BF, Afdhal NH. Squamous metaplasia of extrahepatic biliary system in an AIDS patient with cryptosporidia and cholangitis. Dig Dis Sci. 1993 May; 38(5):960-2. PMID: 8482197

Winawer SJ, Zauber AG, O'Brien MJ, Ho MN, Gottlieb L, Sternberg SS, Waye JD, Bond J, Schapiro M, Stewart ET, et al. Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. The National Polyp Study Workgroup. N Engl J Med. 1993 Apr 1; 328(13):901-6. PMID: 8446136

Fisher ER, Anderson S, Redmond C, Fisher B, Anzola E, Beecher T, Lomotan A, Newkirk R, Bennett B, Shrago S, Kingsley WB, Glenn G, O’Brien MJ, Wotiz H, Ainsworth AM, DePillis VJ, Rowand CW, Strumis P, Watts H, et al . Pathology findings from the National Surgical Adjuvant Breast Project protocol B-06: 10-year pathologic and clinical prognostic discriminants. Cancer. 1993; 2507-2514.

Winawer SJ, Zauber AG, O'Brien MJ, Gottlieb LS, Sternberg SS, Stewart ET, Bond JH, Schapiro M, Panish JF, Waye JD, et al. The National Polyp Study. Design, methods, and characteristics of patients with newly diagnosed polyps. The National Polyp Study Workgroup. Cancer. 1992 Sep 1; 70(5 Suppl):1236-45. PMID: 1511370

O'Brien MJ, O'Keane JC, Zauber A, Gottlieb LS, Winawer SJ. Precursors of colorectal carcinoma. Biopsy and biologic markers. Cancer. 1992 Sep 1; 70(5 Suppl):1317-27. PMID: 1511379

O'Keane JC, Stahl D, Sheahan K, Burke B, Gottlieb LS, O'Brien MJ. Analysis of epithelial and lymphoid phenotypic markers in relation to growth pattern of colorectal adenomas. Hum Pathol. 1992 Sep; 23(9):1038-43.View Related Profiles.

Sheahan, Kieran
O'Brien, Michael

PMID: 1381333

Winawer SJ, O'Brien MJ, Waye JD, Shike M, Kurtz RC, Schapiro M . Surveillance Following Polypectomy. In: Rossini FP, Lynch HT, Winawer SJ. In: Recent Progress in Colorectal Cancer: Biology and Management of High Risk Groups. Elsevier Science Publishers, B.V. Amsterdam. 1992; 83-88.
O'Brien MJ, Waye JD, Winawer SJ . Colorectal Polyps. Chapter 22, in Management of Gastrointestinal Diseases. Ed Winawer SJ(ed). Gower Inc. New York,NY. 1992.
O'Brien MJ, O'Keane JC, Gottlieb LS, Zauber AG, Winawer SJ. Adenoma Progression to Carcinoma: Classification of Phenotypic Changes. in Rossini FR et al(eds): Recent Progree in Colorectal Cancer: Biology and Management of High-Risk Groups. Elsevier. Amsterdam. 1992; 59-65.
O'Brien MJ, Waye JD, Winawer SJ . Colorectal Polyps. Chapter 3, in Gastrointestinal Cancer, Winawer SJ, Kurtz RC (eds). Gower. New York,NY. 1992.

Lee VW, Fuller JD, O'Brien MJ, Parker DR, Cooley TP, Liebman HA. Pulmonary Kaposi sarcoma in patients with AIDS: scintigraphic diagnosis with sequential thallium and gallium scanning. Radiology. 1991 Aug; 180(2):409-12.View Related Profiles.

Fuller, Jon
O'Brien, Michael
Cooley, Timothy

PMID: 2068302

Winawer SJ, Zauber AG, Stewart E, O'Brien MJ. The natural history of colorectal cancer. Opportunities for intervention. Cancer. 1991 Feb 15; 67(4 Suppl):1143-9. PMID: 1991272

O'Keane JC, Kupchik HZ, Schroy PC, Andry CD, Collins E, O'Brien MJ. A three-dimensional system for long-term culture of human colorectal adenomas. Am J Pathol. 1990 Dec; 137(6):1539-47.View Related Profiles.

Andry, Christopher
O'Brien, Michael
Schroy, Paul

PMID: 2260636; PMCID: PMC1877731

Loftus BM, Gilmartin LG, O'Brien MJ, Carney DN, Dervan PA. Intratubular germ cell neoplasia of the testis: identification by placental alkaline phosphatase immunostaining and argyrophilic nucleolar organizer region quantification. Hum Pathol. 1990 Sep; 21(9):941-8. PMID: 1697556

Sheahan K, O'Brien MJ, Burke B, Dervan PA, O'Keane JC, Gottlieb LS, Zamcheck N. Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am J Clin Pathol. 1990 Aug; 94(2):157-64.View Related Profiles.

Sheahan, Kieran
O'Brien, Michael

PMID: 1695478

Kupchik HZ, Collins EA, O'Brien MJ, McCaffrey RP. Chemotherapy screening assay using 3-dimensional cell culture. Cancer Lett. 1990 May 15; 51(1):11-6. PMID: 2337892

O'Brien MJ, Winawer SJ, Zauber AG, Gottlieb LS, Sternberg SS, Diaz B, Dickersin GR, Ewing S, Geller S, Kasimian D, et al. The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology. 1990 Feb; 98(2):371-9. PMID: 2403953

O'Keane JC, Okon E, Moroz K, Burke B, Sheahan K, O'Brien MJ. Anti-estradiol immunoperoxidase labeling of nuclei, not cytoplasm, in paraffin sections, determines estrogen receptor status of breast cancer. Am J Surg Pathol. 1990 Feb; 14(2):121-7.View Related Profiles.

Sheahan, Kieran
O'Brien, Michael

PMID: 2154140

Winawer SJ, O'Brien MJ, Waye JD, Kronborg O, Bond J, Frühmorgen P, Sobin LH, Burt R, Zauber A, Morson B. Risk and surveillance of individuals with colorectal polyps. Who Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990; 68(6):789-95. PMID: 2073716; PMCID: PMC2393163

Johnston PG, O'Brien MJ, Dervan PA, Carney DN. Immunohistochemical analysis of cell kinetic parameters in colonic adenocarcinomas, adenomas, and normal mucosa. Hum Pathol. 1989 Jul; 20(7):696-700. PMID: 2661411

Dervan PA, Tobbia IN, Casey M, O'Loughlin J, O'Brien M. Glomus tumours: an immunohistochemical profile of 11 cases. Histopathology. 1989 May; 14(5):483-91. PMID: 2544504

O'Brien MJ, Winawer SJ, Zauber A, Diaz B, Gottlieb LS, Bond J, Geenen J, Hogan W, Panish JF, Waye JD, Schapiro M and the National Polyp Study Workgroup . The United States National Polyp Study. In Accomplishments in Oncology. JB Lippincott. 1989; 3: 7:211-224.

Bulger K, O'Riordan M, Purdy S, O'Brien M, Lennon J. Gastrointestinal sarcoidosis resembling Crohn's disease. Am J Gastroenterol. 1988 Dec; 83(12):1415-7. PMID: 3195549

Bulger K, Griffin M, O'Brien M, Crowe J. Lymphoma in the mesenteric lymph node cavitation syndrome. Gastroenterology. 1988 Feb; 94(2):553. PMID: 3335328

Winawer SJ, Gottlieb LS, O'Brien MJ, et al . The National Polyp Study: An Overview and Preliminary Report. In Basic and Clinical Perspective of Colorectal Polyps. Karr JP, Ed. Alan R Liss, Inc. New York,NY. 1988; 35-49.

Winawer SJ, Zauber A, Diaz B, O'Brien M, Gottlieb LS, Sternberg SS, Waye JD, Shike M. The National Polyp Study: overview of program and preliminary report of patient and polyp characteristics. Prog Clin Biol Res. 1988; 279:35-49. PMID: 3054929

Murray FE, O'Brien MJ, Birkett DH, Kennedy SM, LaMont JT. Diversion colitis. Pathologic findings in a resected sigmoid colon and rectum. Gastroenterology. 1987 Dec; 93(6):1404-8. PMID: 3678755

Spigelman Z, Dowers A, Kennedy S, DiSorbo D, O'Brien M, Barr R, McCaffrey R. Antiproliferative effects of suramin on lymphoid cells. Cancer Res. 1987 Sep 1; 47(17):4694-8. PMID: 3621163

Triadafilopoulos G, Pothoulakis C, O'Brien MJ, LaMont JT. Differential effects of Clostridium difficile toxins A and B on rabbit ileum. Gastroenterology. 1987 Aug; 93(2):273-9. PMID: 3596162

Brady K, Page DV, Benn LE, de las Morenas A, O'Brien M. Ovarian myxoma. Am J Obstet Gynecol. 1987 May; 156(5):1240-2.View Related Profiles.

De Las Morenas, Antonio
O'Brien, Michael

PMID: 3555091

el-Deriny SE, O'Brien MJ, Christensen TG, Kupchik HZ. Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. Pancreas. 1987; 2(1):25-33. PMID: 3575313

Primrose WJ, McDonald GA, O'Brien MJ, Vaughan CW, Strong MS. Synergistic effects of sequential carbon dioxide and neodymium:yttrium aluminum garnet laser injuries. Experimental observations and measurements. Ann Otol Rhinol Laryngol. 1987 Jan-Feb; 96(1 Pt 1):47-52.View Related Profiles.

Strong, M.
O'Brien, Michael

PMID: 3545019

Niles RM, Wilhelm SA, Steele GD, Burke B, Christensen T, Dexter D, O'Brien MJ, Thomas P, Zamcheck N. Isolation and characterization of an undifferentiated human colon carcinoma cell line (MIP-101). Cancer Invest. 1987; 5(6):545-52. PMID: 3442732

Pietrafitta JJ, Anderson BG, O'Brien MJ, Deckers PJ. Cholecystitis secondary to infusion chemotherapy. J Surg Oncol. 1986 Apr; 31(4):287-93. PMID: 2941626

Lee VW, Peng TT, O'Brien MJ, Hauck RM. Budd-Chiari syndrome complicating hepatocellular carcinoma. Demonstration by multiple radiotracer scintigraphy. Clin Nucl Med. 1986 Feb; 11(2):102-7. PMID: 3021372

Lee VW, O'Brien MJ, Morris PM, Devereux DF, Shapiro JH. The specific diagnosis of hepatocellular carcinoma by scintigraphy. Multiple radiotracer approach. Cancer. 1985 Jul 1; 56(1):25-36. PMID: 2988735

Lee VW, O'Brien MJ, Devereux DF, Morris PM, Shapiro JH. Hepatocellular carcinoma: uptake of 99mTc-IDA in primary tumor and metastasis. AJR Am J Roentgenol. 1984 Jul; 143(1):57-61. PMID: 6328961

Devereux DF, Kavanah MT, Feldman MI, Kondi E, Hull D, O'Brien M, Deckers PJ, Mozden PJ. Small bowel exclusion from the pelvis by a polyglycolic acid mesh sling. J Surg Oncol. 1984 Jun; 26(2):107-12.View Related Profiles.

Kavanah, Maureen
O'Brien, Michael

PMID: 6330456

Tracey KJ, O'Brien MJ, Williams LF, Klibaner M, George PK, Saravis CA, Zamcheck N. Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma. Dig Dis Sci. 1984 Jun; 29(6):573-6. PMID: 6327210

Dayal Y, Doos WG, O'Brien MJ, Nunnemacher G, DeLellis RA, Wolfe HJ. Psammomatous somatostatinomas of the duodenum. Am J Surg Pathol. 1983 Oct; 7(7):653-65. PMID: 6139028

Kupchik HZ, Langer RS, Haberern C, El Deriny S, O'Brien M. A new method for the three-dimensional in vitro growth of human cancer cells. Exp Cell Res. 1983 Sep; 147(2):454-60. PMID: 6352294

Goslin RH, O'Brien MJ, Skarin AT, Zamcheck N. Immunocytochemical staining for CEA in small cell carcinoma of lung predicts clinical usefulness of the plasma assay. Cancer. 1983 Jul 15; 52(2):301-6. PMID: 6305471

deVere White R, O'Brien M, Krikorian J, Babayan R, Olsson CA. Maytansine as a cause of acute proliferative disorder of bladder urothelium in the rat. Cancer Treat Rep. 1983 Feb; 67(2):183-4.View Related Profiles.

O'Brien, Michael
Babayan, Richard

PMID: 6825127

Rau P, O'Brien M, Ezpeleta M, Williams L, Kramer P, Burakoff R. Bleeding Meckel's diverticulum in a patient with inflammatory bowel disease. J Clin Gastroenterol. 1982 Oct; 4(5):455-9. PMID: 6983539

George PK, Loewenstein MS, O'Brien MJ, Bronstein B, Koff RS, Zamcheck N. Circulating CEA levels in patients with fulminant hepatitis. Dig Dis Sci. 1982 Feb; 27(2):139-42. PMID: 7075408

Laffal LD, Bond JH, Decosse JJ, O'Brien MJ . Colorectal Cancer, Surgical Management, Clinical Roundtables. 1982; 15:1-8.

Goslin R, O'Brien MJ, Steele G, Mayer R, Wilson R, Corson JM, Zamcheck N. Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer. Am J Med. 1981 Aug; 71(2):246-53. PMID: 6167166

O'Brien MJ, Zamcheck N, Burke B, Kirkham SE, Saravis CA, Gottlieb LS. Immunocytochemical localization of carcinoembryonic antigen in benign and malignant colorectal tissues. Assessment of diagnostic value. Am J Clin Pathol. 1981 Mar; 75(3):283-90. PMID: 7010989

O'Brien MJ, Kirkham SE, Burke B, Ormerod M, Saravis CA, Gottlieb LS, Neville AM, Zamcheck N. CEA, ZGM and EMA localization in cells of pleural and peritoneal effusion: a preliminary study. Invest Cell Pathol. 1980 Jul-Sep; 3(3):251-8. PMID: 6159337

O'Brien MJ, Bronstein B, Zamcheck N, Saravis C, Burke B, Gottlieb LS. Cholestasis and hepatic metastases: a factor contributing to extreme elevations of carcinoembryonic antigen. J Natl Cancer Inst. 1980 Jun; 64(6):1291-4. PMID: 6246298

O'Brien MJ, Gottlieb LS . The Liver and Biliary Tract in: Pathologic Basis of Disease, Chapter 21. Robbins S, Cotran R, Eds. W.B. Saunders Co. Philadelphia,PA. 1979.

Saravis CA, O'Brien M, Zamcheck N. Direct tissue isoelectric focusing in agarose. J Immunol Methods. 1979; 29(1):97-100. PMID: 385785

Saravis CA, Kupchick HZ, O'Brien MJ, Zamcheck N . Zinc Glycinate Marker (ZGM). In Compendium of Assays for Immunodiagnosis of Human Cancer. Herberman R Ed. Elsevier-North Holland, Inc. 1979; 1:237-239.

Walsh MJ, O'Brien M, McCarthy CF. Chronic active liver disease: experiences with 17 patients. Ir J Med Sci. 1978 Jul; 147(7):223-9. PMID: 681148

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 161 publications over 41 distinct years, with a maximum of 13 publications in 2006

Bar chart showing 161 publications over 41 distinct years, with a maximum of 13 publications in 2006

Year	Publications
1980	2
1981	2
1982	3
1983	4
1984	3
1985	1
1986	2
1987	7
1988	4
1989	3
1990	7
1991	2
1992	7
1993	6
1994	2
1995	3
1996	7
1997	2
1998	3
1999	1
2000	4
2001	1
2002	2
2003	4
2004	8
2005	3
2006	13
2007	5
2008	8
2009	4
2010	2
2011	5
2012	5
2013	6
2014	8
2015	4
2016	2
2017	3
2020	1
2023	1
2024	1

2010 ASGE: Committee on Real Time Histological Methods in Clinical Practice

2010 Exploring Serrated Polyps of the Colon, Cleveland Clinic: NIH Consensus Conference

2009 New England Society of Pathologists: President

2009 National University of Ireland, Galway: Medtronic Distinguished Alumnus Award

2008 Irish National Cancer Screening Service: Member, International Validation Panel

2006 Royal College of Physicians of Ireland: Fellow, Faculty of Pathology (Hon)

2006-2011 Irish Cancer Society: Consultant, Cancer Research Ireland

2004 US National Taskforce on Colon Cancer: Member

2003 American College of Gastroenterology: Fellow

2001-2006 College of American Pathologists: Member, Surgical Pathology Committee

1997 International Academy of Cytology: Chairman, Task Force on Digital Imaging

1992 Management of Colon Polyps, American College of Gastroenterology: Consultant to Committee on Practice Guidelines

1992 WHO: Committee on Guidelines for colorectal cancer screening and surveillance

1992 American Journal of Surgical Pathology: Editorial Board

1989-2012 Fellow of the Royal College of Pathologists (UK)

1988-1998 World Health Organization Collaborating Center for Prevention of Colorectal Cancer: Advisory Board

1981-1991 National Polyp Study: Consultant Pathologist

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Anatomic pathology
Cytopathology
Colorectal Cancer

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