Mary Brophy | Profiles RNS

Mary Brophy, MD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Hematology & Medical Oncology

MD, Tufts University School of Medicine
BS, Stonehill College

Websites

	MAVERIC
	BUSM
	Harvard
	Research Gate

Member
Boston University
BU-BMC Cancer Center

VA Boston Healthcare System

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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La J, Hshieh T, Hamparsumian A, Zwolinski R, Wood J, Dharne M, Gaziano JM, Brophy MT, Do NV, Munshi NC, Driver JA, Abel GA, Fillmore NR, DuMontier C. Potentially Inappropriate Medications, Frailty, and Outcomes in Patients With Cancer Managed in a National Health Care System. J Natl Compr Canc Netw. 2025 Sep; 23(9):363-370.View Related Profiles.

Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 40930142

Barry A, England BR, Sayles H, Helget LN, Androsenko M, Wu H, Michaud K, Kramer B, Newcomb JA, Brophy MT, Davis-Karim A, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, O'Dell JR, Mikuls TR. Improvements in Health-Related Quality of Life With Treat-to-Target Urate-Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial. Arthritis Care Res (Hoboken). 2025 Aug 07.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 40771143; DOI: 10.1002/acr.25618;

Kohn S, Sayles H, Helget LN, England BR, Roul P, Newcomb JA, Kramer B, Davis-Karim A, Brophy MT, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, O'Dell JR, Mikuls TR. Real-world persistence of urate-lowering therapy following a treat-to-target intervention: A two-year follow-up analysis of the STOP gout trial. Semin Arthritis Rheum. 2025 Oct; 74:152800.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 40782426; DOI: 10.1016/j.semarthrit.2025.152800;

Kim DY, Huhmann L, Hippe DS, Wheless L, Pavlis M, Hwang JC, Brophy MT, Do NV, Nghiem P, Fillmore N, Hartman RI. Treatment and disease-specific survival differences among veterans with Merkel cell carcinoma. J Am Acad Dermatol. 2025 Oct; 93(4):1103-1106.View Related Profiles.

Brophy, Mary
Fillmore, Nathanael

PMID: 40490100

Moncayo AK, Ferguson JM, Dizon MP, Huhmann L, Kim DY, Do N, Brophy MT, Osborne TF, Spence AC, Fillmore NR, Swetter SM, Hartman RI. Area Deprivation Index and Melanoma Thickness in Veterans. JAMA Dermatol. 2025 Jun 01; 161(6):582-588.View Related Profiles.

Brophy, Mary
Fillmore, Nathanael

PMID: 40047783; PMCID: PMC11886871; DOI: 10.1001/jamadermatol.2025.0311;

Lee MH, La J, Brophy MT, Do NV, Edwards CV, DuMontier C, Hobbs GS, Fillmore NR. Psychiatric and substance use disorders predict poor outcomes in older veterans with acute myeloid leukemia. Blood Adv. 2025 Apr 08; 9(7):1555-1558.View Related Profiles.

Edwards, Camille
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 39715463; PMCID: PMC11986211; DOI: 10.1182/bloodadvances.2024014468;

Larsen JR, Zheng C, La J, Wu JT, Kelley M, Gaziano JM, Brophy M, Do NV, Kim DH, Driver JA, DuMontier C, Fillmore NR. Multimorbidity and Its Impact in Older U.S. Veterans Newly Treated for Advanced Non-Small Cell Lung Cancer. Ann Am Thorac Soc. 2025 Apr; 22(4):598-608.View Related Profiles.

Zheng, Chunlei
Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 39680869; PMCID: PMC12005025; DOI: 10.1513/AnnalsATS.202406-587OC;

Swinnerton K, Fillmore NR, Vo A, La J, Elbers D, Brophy M, Do NV, Monach PA, Branch-Elliman W. Leveraging near-real-time patient and population data to incorporate fluctuating risk of severe COVID-19: development and prospective validation of a personalised risk prediction tool. EClinicalMedicine. 2025 Mar; 81:103114.View Related Profiles.

Elbers, Danne
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Branch-Elliman, Westyn

PMID: 40070694; PMCID: PMC11893359; DOI: 10.1016/j.eclinm.2025.103114;

Swinnerton K, Fillmore NR, Oboho I, Grubber J, Brophy M, Do NV, Monach PA, Branch-Elliman W. Pulmonary aspergillosis in US Veterans with COVID-19: a nationwide, retrospective cohort study. Antimicrob Steward Healthc Epidemiol. 2025; 5(1):e28.View Related Profiles.

Brophy, Mary
Fillmore, Nathanael
Branch-Elliman, Westyn

PMID: 39911504; PMCID: PMC11795435; DOI: 10.1017/ash.2024.476;

Ferri GM, Yildirim C, Do NV, Brophy M, Park JS, Munshi NC, Fillmore NR, Edwards CV. Lymphopenia predicts poor outcomes in newly diagnosed multiple myeloma. Blood Adv. 2025 Jan 14; 9(1):78-88.View Related Profiles.

Edwards, Camille
Ferri, Grace
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 39471425; PMCID: PMC11742561; DOI: 10.1182/bloodadvances.2024014125;

Showing 10 of 123 results. Show More

Wu JT, Corrigan J, Su C, Dumontier C, La J, Khan A, Arya S, Harris AHS, Backhus L, Das M, Do NV, Brophy MT, Han SS, Kelley M, Fillmore NR. Correction: The performance status gap in immunotherapy for frail patients with advanced non-small cell lung cancer. Cancer Immunol Immunother. 2024 Dec 30; 74(1):34.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 39739108; PMCID: PMC11685335; DOI: 10.1007/s00262-024-03875-3;

Dulberger KN, La J, Li A, Lotfollahzadeh S, Jose A, Do NV, Brophy MT, Gaziano JM, Ravid K, Chitalia VC, Fillmore NR. External validation of a novel cancer-associated venous thromboembolism risk assessment score in a safety-net hospital. Res Pract Thromb Haemost. 2025 Jan; 9(1):102650.View Related Profiles.

Jose, Asha
Gaziano, J. Michael
La, Jennifer
Dulberger, Karlynn
Ravid, Katya
Brophy, Mary
Fillmore, Nathanael
Lotfollahzadeh, Saran
Chitalia, Vipul

PMID: 39839661; PMCID: PMC11745955; DOI: 10.1016/j.rpth.2024.102650;

La J, Wang L, Corrigan JK, Lang D, Lee MH, Do NV, Brophy MT, Paller CJ, Fillmore NR. Abiraterone or Enzalutamide for Patients With Metastatic Castration-Resistant Prostate Cancer. JAMA Netw Open. 2024 Aug 01; 7(8):e2428444.View Related Profiles.

Lang, Deborah
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 39150709; PMCID: PMC11329885; DOI: 10.1001/jamanetworkopen.2024.28444;

Barry A, Helget LN, Androsenko M, Wu H, Kramer B, Newcomb JA, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Merriman TR, O'Dell JR, Mikuls TR. Comparison of Gout Flares With the Initiation of Treat-to-Target Allopurinol and Febuxostat: A Post-Hoc Analysis of a Randomized Multicenter Trial. Arthritis Rheumatol. 2024 Oct; 76(10):1552-1559.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 38925627; PMCID: PMC11421957; DOI: 10.1002/art.42927;

Kim RB, Zhou E, Swinnerton KN, La J, Ma S, Ranjan M, Do NV, Brophy MT, Fillmore NR, Li A. Racial and Ethnic Disparity for Cancer Mortality in General and Single-Payer Healthcare Systems in the United States. J Racial Ethn Health Disparities. 2025 Aug; 12(4):2646-2654.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 38955957; PMCID: PMC11693772; DOI: 10.1007/s40615-024-02077-y;

Wu JT, Corrigan J, Su C, Dumontier C, La J, Khan A, Arya S, Harris AHS, Backhus L, Das M, Do NV, Brophy MT, Han SS, Kelley M, Fillmore NR. The performance status gap in immunotherapy for frail patients with advanced non-small cell lung cancer. Cancer Immunol Immunother. 2024 Jul 02; 73(9):172.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 38954019; PMCID: PMC11219626; DOI: 10.1007/s00262-024-03763-w;

Goryachev SD, Yildirim C, DuMontier C, La J, Dharne M, Gaziano JM, Brophy MT, Munshi NC, Driver JA, Do NV, Fillmore NR. Natural Language Processing Algorithm to Extract Multiple Myeloma Stage From Oncology Notes in the Veterans Affairs Healthcare System. JCO Clin Cancer Inform. 2024 Jul; 8:e2300197.View Related Profiles.

Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 39038255; PMCID: PMC11371094; DOI: 10.1200/CCI.23.00197;

Helget LN, Davis-Karim A, O'Dell JR, Mikuls TR, Newcomb JA, Androsenko M, Brophy MT, England BR, Ferguson R, Pillinger MH, Neogi T, Wu H, Palevsky PM. Efficacy and Safety of Allopurinol and Febuxostat in Patients With Gout and CKD: Subgroup Analysis of the STOP Gout Trial. Am J Kidney Dis. 2024 Nov; 84(5):538-545.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 38906504

Ramos-Cejudo J, Corrigan JK, Zheng C, Swinnerton KN, Jacobson SR, La J, Betensky RA, Osorio RS, Madanes S, Pomara N, Iosifescu D, Brophy M, Do NV, Fillmore NR. Antidepressant exposure and long-term dementia risk in a nationwide retrospective study on US veterans with midlife major depressive disorder. Alzheimers Dement. 2024 Jun; 20(6):4106-4114.View Related Profiles.

Zheng, Chunlei
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 38717046; PMCID: PMC11180845; DOI: 10.1002/alz.13853;

Feldman TC, Kaplan DE, Lin A, La J, Lee JSH, Aljehani M, Tuck DP, Brophy MT, Fillmore NR, Do NV. Phenotyping Hepatic Immune-Related Adverse Events in the Setting of Immune Checkpoint Inhibitor Therapy. JCO Clin Cancer Inform. 2024 May; 8:e2300159.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 38728613; PMCID: PMC11161238; DOI: 10.1200/CCI.23.00159;

Bigdeli TB, Barr PB, Rajeevan N, Graham DP, Li Y, Meyers JL, Gorman BR, Peterson RE, Sayward F, Radhakrishnan K, Natarajan S, Nielsen DA, Wilkinson AV, Malhotra AK, Zhao H, Brophy M, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Pyarajan S, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, DeLisi LE, Kimbrel NA, Beckham JC, Swann AC, Kosten TR, Fanous AH, Aslan M, Harvey PD. Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder. Mol Psychiatry. 2024 Aug; 29(8):2399-2407.View Related Profiles.

Gaziano, J. Michael
Brophy, Mary

PMID: 38491344

Anand ST, Vo AD, La J, Do NV, Fillmore NR, Brophy M, Branch-Elliman W, Monach PA. Severe COVID-19 in Vaccinated Adults With Hematologic Cancers in the Veterans Health Administration. JAMA Netw Open. 2024 Feb 05; 7(2):e240288.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Branch-Elliman, Westyn

PMID: 38393725; PMCID: PMC10891464; DOI: 10.1001/jamanetworkopen.2024.0288;

Bihn JR, Cioffi G, Waite KA, Kruchko C, Neff C, Price M, Ostrom QT, Swinnerton KN, Elbers DC, Mooney MA, Rachlin J, Stein TD, Brophy MT, Do NV, Ferguson RE, Priemer DS, Perl DP, Hickman RA, Nabors B, Rusiecki J, Barnholtz-Sloan JS, Fillmore NR. Brain tumors in United States military veterans. Neuro Oncol. 2024 Feb 02; 26(2):387-396.View Related Profiles.

Elbers, Danne
Brophy, Mary
Fillmore, Nathanael
Ferguson, Ryan
Stein, Thor

PMID: 37738677; PMCID: PMC10836768; DOI: 10.1093/neuonc/noad182;

Clark M, Meyer C, Ramos-Cejudo J, Elbers DC, Pierce-Murray K, Fricks R, Alterovitz G, Rao L, Brophy MT, Do NV, Grossman RL, Fillmore NR. Transfer Learning for Mortality Prediction in Non-Small Cell Lung Cancer with Low-Resolution Histopathology Slide Snapshots. Stud Health Technol Inform. 2024 Jan 25; 310:735-739.View Related Profiles.

Elbers, Danne
Brophy, Mary
Fillmore, Nathanael
Fricks, Rafael

PMID: 38269906; PMCID: PMC11128309; DOI: 10.3233/SHTI231062;

Do NV, Elbers DC, Fillmore NR, Ajjarapu S, Bergstrom SJ, Bihn J, Corrigan JK, Dhond R, Dipietro S, Dolgin A, Feldman TC, Goryachev SD, Huhmann LB, La J, Marcantonio PA, McGrath KM, Miller SJ, Nguyen VQ, Schneeloch GR, Sung FC, Swinnerton KN, Tarren AH, Tosi HM, Valley D, Vo AD, Yildirim C, Zheng C, Zwolinski R, Sarosy GA, Loose D, Shannon C, Brophy MT. Matching Patients to Accelerate Clinical Trials (MPACT): Enabling Technology for Oncology Clinical Trial Workflow. Stud Health Technol Inform. 2024 Jan 25; 310:1086-1090.View Related Profiles.

Zheng, Chunlei
Elbers, Danne
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Ajjarapu, Samuel

PMID: 38269982; PMCID: PMC11128308; DOI: 10.3233/SHTI231132;

Elbers DC, Fillmore NR, La J, Tosi HM, Ajjarapu S, Dhond R, Murray K, Valley D, Shannon C, Brophy MT, Do NV. Building Research Infrastructure to Develop Greater Learning Efficiencies (BRIDGE). Stud Health Technol Inform. 2024 Jan 25; 310:1131-1135.View Related Profiles.

Elbers, Danne
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Ajjarapu, Samuel

PMID: 38269991; PMCID: PMC11166042; DOI: 10.3233/SHTI231141;

Hernandez KM, Venkat A, Elbers DC, Bihn JR, Brophy MT, Do NV, La J, Liu Q, Prokhorenkov A, Metoki-Shlubsky N, Sung FC, Paller CJ, Fillmore NR, Grossman RL. Prostate cancer patient stratification by molecular signatures in the Veterans Precision Oncology Data Commons. Cold Spring Harb Mol Case Stud. 2023 Dec; 9(4).View Related Profiles.

Elbers, Danne
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 38050021; PMCID: PMC10815278; DOI: 10.1101/mcs.a006298;

Helget LN, O'Dell JR, Newcomb JA, Androsenko M, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, Kramer B, Mikuls TR. Determinants of Achieving Serum Urate Goal with Treat-to-Target Urate-Lowering Therapy in Gout. Arthritis Rheumatol. 2024 Apr; 76(4):638-646.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 37842953; PMCID: PMC10965366; DOI: 10.1002/art.42731;

Anand ST, Vo AD, La J, Brophy M, Do NV, Fillmore NR, Branch-Elliman W, Monach PA. Risk of severe coronavirus disease 2019 despite vaccination in patients requiring treatment with immune-suppressive drugs: A nationwide cohort study of US Veterans. Transpl Infect Dis. 2024 Feb; 26(1):e14168.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Branch-Elliman, Westyn

PMID: 37966134

Fillmore NR, La J, Wu JT, Corrigan JK, Branch-Elliman W, Monach P, Brophy MT, Do NV, Munshi NC. Even after SARS-CoV-2 booster, there is increased COVID-19 breakthrough infection in patients with plasma cell disorders. Blood Adv. 2023 Nov 14; 7(21):6767-6770.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.
Branch-Elliman, Westyn

PMID: 37647600; PMCID: PMC10659994; DOI: 10.1182/bloodadvances.2023011063;

DuMontier C, La J, Bihn J, Corrigan J, Yildirim C, Dharne M, Hassan H, Yellapragada S, Abel GA, Gaziano JM, Do NV, Brophy M, Kim DH, Munshi NC, Fillmore NR, Driver JA. More intensive therapy has a better effect for frail parents with multiple myeloma. Blood Adv. 2023 Oct 24; 7(20):6275-6284.View Related Profiles.

Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 37582048; PMCID: PMC10589796; DOI: 10.1182/bloodadvances.2023011019;

La J, Lee MH, Brophy MT, Do NV, Driver JA, Tuck DP, Fillmore NR, Dumontier C. Baseline correlates of frailty and its association with survival in United States veterans with acute myeloid leukemia. Leuk Lymphoma. 2023 Dec; 64(13):2081-2090.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 37671705; PMCID: PMC12087472; DOI: 10.1080/10428194.2023.2254434;

Merjanah S, Liew JW, Bihn J, Fillmore NR, Brophy MT, Do NV, Dubreuil M. Trends in Fracture Rates Over Two Decades Among Veterans With Ankylosing Spondylitis. Arthritis Care Res (Hoboken). 2023 Dec; 75(12):2481-2488.View Related Profiles.

Liew, Jean
Brophy, Mary
Dubreuil, Maureen
Fillmore, Nathanael
Merjanah, Sali

PMID: 37308459; PMCID: PMC10704387; DOI: 10.1002/acr.25166;

Martens KL, Li A, La J, May SB, Swinnerton KN, Tosi H, Elbers DC, Do NV, Brophy MT, Gaziano JM, Lotfollahzadeh S, Chitalia V, Ravid K, Fillmore NR. Epidemiology of Cancer-Associated Venous Thromboembolism in Patients With Solid and Hematologic Neoplasms in the Veterans Affairs Health Care System. JAMA Netw Open. 2023 Jun 01; 6(6):e2317945.View Related Profiles.

Elbers, Danne
Gaziano, J. Michael
La, Jennifer
Ravid, Katya
Brophy, Mary
Fillmore, Nathanael
Lotfollahzadeh, Saran
Chitalia, Vipul

PMID: 37306999; PMCID: PMC10261992; DOI: 10.1001/jamanetworkopen.2023.17945;

Li A, May SB, La J, Martens KL, Amos CI, Flowers CR, Do NV, Brophy MT, Chitalia V, Ravid K, Gaziano JM, Fillmore NR. Venous thromboembolism risk in cancer patients receiving first-line immune checkpoint inhibitor versus chemotherapy. Am J Hematol. 2023 Aug; 98(8):1214-1222.View Related Profiles.

Gaziano, J. Michael
La, Jennifer
Ravid, Katya
Brophy, Mary
Fillmore, Nathanael
Chitalia, Vipul

PMID: 37161855; PMCID: PMC10569448; DOI: 10.1002/ajh.26954;

Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, Regev A, Ayandeh S, Brophy MT, Do NV, Kraft P, Wolpin BM, Rosenthal MH, Fillmore NR, Brunak S, Sander C. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nat Med. 2023 May; 29(5):1113-1122.View Related Profiles.

Zheng, Chunlei
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 37156936; PMCID: PMC10202814; DOI: 10.1038/s41591-023-02332-5;

Ferguson RE, Leatherman SM, Woods P, Hau C, Lew R, Cushman WC, Brophy MT, Fiore L, Ishani A. Practical issues in pragmatic trials: the implementation of the Diuretic Comparison Project. Clin Trials. 2023 Jun; 20(3):276-283.View Related Profiles.

Fiore, Louis
Brophy, Mary
Lew, Robert
Ferguson, Ryan
Leatherman, Sarah

PMID: 36992530

Bigdeli TB, Barr PB, Rajeevan N, Graham DP, Li Y, Meyers JL, Gorman BR, Peterson RE, Sayward F, Radhakrishnan K, Natarajan S, Nielsen DA, Wilkinson AV, Malhotra AK, Zhao H, Brophy M, Shi Y, Oâ Leary TJ, Gleason T, Przygodzki R, Pyarajan S, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, DeLisi LE, Kimbrel NA, Beckham JC, Swann AC, Kosten TR, Fanous AH, Aslan M, Harvey PD. Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder. medRxiv. 2023 Mar 08.View Related Profiles.

Gaziano, J. Michael
DeLisi, Lynn
Brophy, Mary

PMID: 36945597; PMCID: PMC10029042; DOI: 10.1101/2023.03.06.23286866;

Ganti AK, Fillmore NR, Bihn J, La J, Brophy MT, Do NV, Kelley M. Risk factors of SARS-CoV-2 infection and complications from COVID-19 in lung cancer patients. Int J Clin Oncol. 2023 Apr; 28(4):531-542.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 36859565; PMCID: PMC9977088; DOI: 10.1007/s10147-023-02311-3;

Elbers DC, La J, Minot JR, Gramling R, Brophy MT, Do NV, Fillmore NR, Dodds PS, Danforth CM. Sentiment analysis of medical record notes for lung cancer patients at the Department of Veterans Affairs. PLoS One. 2023; 18(1):e0280931.View Related Profiles.

Elbers, Danne
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 36696437; PMCID: PMC9876289; DOI: 10.1371/journal.pone.0280931;

Li A, La J, May SB, Guffey D, da Costa WL, Amos CI, Bandyo R, Milner EM, Kurian KM, Chen DCR, Do NV, Granada C, Riaz N, Brophy MT, Chitalia V, Gaziano JM, Garcia DA, Carrier M, Flowers CR, Zakai NA, Fillmore NR. Derivation and Validation of a Clinical Risk Assessment Model for Cancer-Associated Thrombosis in Two Unique US Health Care Systems. J Clin Oncol. 2023 Jun 01; 41(16):2926-2938.View Related Profiles.

Chen, Daniel
Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Chitalia, Vipul

PMID: 36626707; PMCID: PMC10431461; DOI: 10.1200/JCO.22.01542;

Dassum SR, Ferguson R, Woods P, Flynn M, Visnaw K, Holmberg E, Schiller S, Shannon C, Brophy M, Monach P, Leatherman S, Branch-Elliman W. Patient- reported reasons for non-participation in a COVID-19 therapeutics clinical trial: Findings from a multi-center investigation. Contemp Clin Trials. 2023 Mar; 126:107082.View Related Profiles.

Brophy, Mary
Leatherman, Sarah
Branch-Elliman, Westyn

PMID: 36632925; PMCID: PMC9827740; DOI: 10.1016/j.cct.2023.107082;

Lin E, Zwolinski R, Wu JT, La J, Goryachev S, Huhmann L, Yildrim C, Tuck DP, Elbers DC, Brophy MT, Do NV, Fillmore NR. Machine learning-based natural language processing to extract PD-L1 expression levels from clinical notes. Health Informatics J. 2023; 29(3):14604582231198021.View Related Profiles.

Elbers, Danne
Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 37635280

La J, DuMontier C, Hassan H, Abdallah M, Edwards C, Verma K, Ferri G, Dharne M, Yildirim C, Corrigan J, Gaziano JM, Do NV, Brophy MT, Driver JA, Munshi NC, Fillmore NR. Validation of algorithms to select patients with multiple myeloma and patients initiating myeloma treatment in the national Veterans Affairs Healthcare System. Pharmacoepidemiol Drug Saf. 2023 May; 32(5):558-566.View Related Profiles.

Edwards, Camille
Ferri, Grace
Hassan, Hamza
Gaziano, J. Michael
La, Jennifer
Verma, Karina
Brophy, Mary
Abdallah, Maya
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 36458420; PMCID: PMC10448707; DOI: 10.1002/pds.5579;

Ishani A, Cushman WC, Leatherman SM, Lew RA, Woods P, Glassman PA, Taylor AA, Hau C, Klint A, Huang GD, Brophy MT, Fiore LD, Ferguson RE. Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events. N Engl J Med. 2022 Dec 29; 387(26):2401-2410.View Related Profiles.

Fiore, Louis
Brophy, Mary
Lew, Robert
Ferguson, Ryan
Leatherman, Sarah

PMID: 36516076

La J, Fillmore NR, Do NV, Brophy M, Monach PA, Branch-Elliman W. Factors associated with the speed and scope of diffusion of COVID-19 therapeutics in a nationwide healthcare setting: a mixed-methods investigation. Health Res Policy Syst. 2022 Dec 14; 20(1):134.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Branch-Elliman, Westyn

PMID: 36517793; PMCID: PMC9749626; DOI: 10.1186/s12961-022-00935-x;

Fillmore NR, Szalat RE, La J, Branch-Elliman W, Monach PA, Nguyen V, Samur MK, Brophy MT, Do NV, Munshi NC. Recent common human coronavirus infection protects against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A Veterans Affairs cohort study. Proc Natl Acad Sci U S A. 2022 Nov 16; 119(46):e2213783119.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.
Szalat, Raphael
Branch-Elliman, Westyn

PMID: 36343242; PMCID: PMC9674225; DOI: 10.1073/pnas.2213783119;

Vo AD, La J, Wu JT, Strymish JM, Ronan M, Brophy M, Do NV, Branch-Elliman W, Fillmore NR, Monach PA. Factors Associated With Severe COVID-19 Among Vaccinated Adults Treated in US Veterans Affairs Hospitals. JAMA Netw Open. 2022 Oct 03; 5(10):e2240037.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Branch-Elliman, Westyn

PMID: 36264571; PMCID: PMC9585432; DOI: 10.1001/jamanetworkopen.2022.40037;

Bigdeli TB, Voloudakis G, Barr PB, Gorman BR, Genovese G, Peterson RE, Burstein DE, Velicu VI, Li Y, Gupta R, Mattheisen M, Tomasi S, Rajeevan N, Sayward F, Radhakrishnan K, Natarajan S, Malhotra AK, Shi Y, Zhao H, Kosten TR, Concato J, O'Leary TJ, Przygodzki R, Gleason T, Pyarajan S, Brophy M, Huang GD, Muralidhar S, Gaziano JM, Aslan M, Fanous AH, Harvey PD, Roussos P. Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System. JAMA Psychiatry. 2022 Sep 14; 79(11):1092-101.View Related Profiles.

Gaziano, J. Michael
Brophy, Mary

PMID: 36103194; PMCID: PMC9475441; DOI: 10.1001/jamapsychiatry.2022.2742;

La J, Wu JT, Branch-Elliman W, Huhmann L, Han SS, Brophy M, Do NV, Lin AY, Fillmore NR, Munshi NC. Increased COVID-19 breakthrough infection risk in patients with plasma cell disorders. Blood. 2022 Aug 18; 140(7):782-785.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.
Branch-Elliman, Westyn

PMID: 35605185; PMCID: PMC9130311; DOI: 10.1182/blood.2022016317;

Corrigan JK, La J, Fillmore NR, Do NV, Brophy M, Doron S, Monach PA, Branch-Elliman W. Coronavirus disease 2019 (COVID-19) hospitalization metrics that do not account for disease severity underestimate protection provided by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) vaccination and boosting: A retrospective cohort study. Infect Control Hosp Epidemiol. 2023 Jan; 44(1):149-151.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Branch-Elliman, Westyn

PMID: 35599374; PMCID: PMC9171062; DOI: 10.1017/ice.2022.79;

Chang MS, La J, Trepanowski N, Cheng D, Bihn JR, Do N, Brophy M, Fillmore NR, Hartman RI. Increased relative proportions of advanced melanoma among veterans: A comparative analysis with the Surveillance, Epidemiology, and End Results registry. J Am Acad Dermatol. 2022 Jul; 87(1):72-79.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 35595121

Ishani A, Leatherman SM, Woods P, Hau C, Klint A, Lew RA, Taylor AA, Glassman PA, Brophy MT, Fiore LD, Ferguson RE, Cushman WC. Design of a pragmatic clinical trial embedded in the Electronic Health Record: The VA's Diuretic Comparison Project. Contemp Clin Trials. 2022 May; 116:106754.View Related Profiles.

Fiore, Louis
Brophy, Mary
Lew, Robert
Ferguson, Ryan
Leatherman, Sarah

PMID: 35390512

Cheng D, Dumontier C, Sheikh AR, La J, Brophy MT, Do NV, Driver JA, Tuck DP, Fillmore NR. Prognostic value of the veterans affairs frailty index in older patients with non-small cell lung cancer. Cancer Med. 2022 Aug; 11(15):3009-3022.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 35338613; PMCID: PMC9359868; DOI: 10.1002/cam4.4658;

Branch-Elliman W, Ferguson R, Doros G, Woods P, Leatherman S, Strymish J, Datta R, Goswami R, Jankowich MD, Shah NR, Taylor TH, Page ST, Schiller SJ, Shannon C, Hau C, Flynn M, Holmberg E, Visnaw K, Dhond R, Brophy M, Monach PA. Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial. PLoS One. 2022; 17(2):e0263591.View Related Profiles.

Doros, Gheorghe
Brophy, Mary
Dhond, Rupali
Leatherman, Sarah
Branch-Elliman, Westyn

PMID: 35213547; PMCID: PMC8880885; DOI: 10.1371/journal.pone.0263591;

O'Dell JR, Brophy MT, Pillinger MH, Neogi T, Palevsky PM, Wu H, Davis-Karim A, Newcomb JA, Ferguson R, Pittman D, Cannon GW, Taylor T, Terkeltaub R, Cannella AC, England BR, Helget LN, Mikuls TR. Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management. NEJM Evid. 2022 Mar; 1(3).View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 35434725; PMCID: PMC9012032; DOI: 10.1056/evidoa2100028;

Cheng D, DuMontier C, Yildirim C, Charest B, Hawley CE, Zhuo M, Paik JM, Yaksic E, Gaziano JM, Do N, Brophy M, Cho K, Kim DH, Driver JA, Fillmore NR, Orkaby AR. Corrigendum to: Updating and Validating the U.S. Veterans Affairs Frailty Index: Transitioning From ICD-9 to ICD-10. J Gerontol A Biol Sci Med Sci. 2022 Feb 03; 77(2):e107.View Related Profiles.

Orkaby, Ariela
Hawley, Chelsea
Gaziano, J. Michael
Brophy, Mary
Fillmore, Nathanael

PMID: 34272940; PMCID: PMC8824613; DOI: 10.1093/gerona/glab159;

Wu JT, La J, Branch-Elliman W, Huhmann LB, Han SS, Parmigiani G, Tuck DP, Brophy MT, Do NV, Lin AY, Munshi NC, Fillmore NR. Association of COVID-19 Vaccination With SARS-CoV-2 Infection in Patients With Cancer: A US Nationwide Veterans Affairs Study. JAMA Oncol. 2022 02 01; 8(2):281-286.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.
Branch-Elliman, Westyn

PMID: 34854921; PMCID: PMC8640949; DOI: 10.1001/jamaoncol.2021.5771;

Dhond R, Acher R, Leatherman S, Page S, Sanford R, Elbers D, Meng F, Ferguson R, Brophy MT, Do NV. Rapid implementation of a modular clinical trial informatics solution for COVID-19 research. Inform Med Unlocked. 2021; 27:100788.View Related Profiles.

Elbers, Danne
Meng, Frank
Brophy, Mary
Van Do, Nhan
Dhond, Rupali
Leatherman, Sarah

PMID: 34786452; PMCID: PMC8588694; DOI: 10.1016/j.imu.2021.100788;

Whiteaker JR, Lundeen RA, Zhao L, Schoenherr RM, Burian A, Huang D, Voytovich U, Wang T, Kennedy JJ, Ivey RG, Lin C, Murillo OD, Lorentzen TD, Thiagarajan M, Colantonio S, Caceres TW, Roberts RR, Knotts JG, Reading JJ, Kaczmarczyk JA, Richardson CW, Garcia-Buntley SS, Bocik W, Hewitt SM, Murray KE, Do N, Brophy M, Wilz SW, Yu H, Ajjarapu S, Boja E, Hiltke T, Rodriguez H, Paulovich AG. Targeted Mass Spectrometry Enables Multiplexed Quantification of Immunomodulatory Proteins in Clinical Biospecimens. Front Immunol. 2021; 12:765898.View Related Profiles.

Brophy, Mary
Van Do, Nhan
Ajjarapu, Samuel
Wilz, Stephen

PMID: 34858420; PMCID: PMC8632241; DOI: 10.3389/fimmu.2021.765898;

Fillmore N, Bell S, Shen C, Nguyen V, La J, Dubreuil M, Strymish J, Brophy M, Mehta G, Wu H, Lieberman J, Do N, Sander C. Disulfiram use is associated with lower risk of COVID-19: A retrospective cohort study. PLoS One. 2021; 16(10):e0259061.View Related Profiles.

La, Jennifer
Brophy, Mary
Dubreuil, Maureen
Fillmore, Nathanael
Van Do, Nhan

PMID: 34710137; PMCID: PMC8553043; DOI: 10.1371/journal.pone.0259061;

Fillmore NR, Cirstea D, Munjuluri A, Yameen H, Yellapragada SV, Do NV, Brophy MT, Szalat RE, Munshi NC. Lack of differential impact of del17p on survival in African Americans compared with White patients with multiple myeloma: a VA study. Blood Adv. 2021 09 28; 5(18):3511-3514.View Related Profiles.

Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.
Szalat, Raphael

PMID: 34428278; PMCID: PMC8945588; DOI: 10.1182/bloodadvances.2020004001;

Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 Jun; 18(6):1248-1259.View Related Profiles.

Zheng, Chunlei
Brophy, Mary
Dubreuil, Maureen
Fillmore, Nathanael
Van Do, Nhan
Au, Rhoda
Qiu, Wendy

PMID: 34569707; PMCID: PMC8957621; DOI: 10.1002/alz.12465;

Dhond R, Elbers D, Majahalme N, Dipietro S, Goryachev S, Acher R, Leatherman S, Anglin-Foote T, Liu Q, Su S, Seerapu R, Hall R, Ferguson R, Brophy MT, Ferraro J, DuVall SL, Do NV. ProjectFlow: a configurable workflow management application for point of care research. JAMIA Open. 2021 Jul; 4(3):ooab074.View Related Profiles.

Elbers, Danne
Brophy, Mary
Van Do, Nhan
Dhond, Rupali
Leatherman, Sarah

PMID: 34485848; PMCID: PMC8411372; DOI: 10.1093/jamiaopen/ooab074;

Fillmore NR, DuMontier C, Yildirim C, La J, Epstein MM, Cheng D, Cirstea D, Yellapragada S, Abel GA, Gaziano JM, Do N, Brophy M, Kim DH, Munshi NC, Driver JA. Defining Multimorbidity and Its Impact in Older United States Veterans Newly Treated for Multiple Myeloma. J Natl Cancer Inst. 2021 08 02; 113(8):1084-1093.View Related Profiles.

Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Munshi, Nikhil C.

PMID: 33523236; PMCID: PMC8328982; DOI: 10.1093/jnci/djab007;

DuMontier C, Fillmore NR, Yildirim C, Cheng D, La J, Orkaby AR, Charest B, Cirstea D, Yellapragada S, Gaziano JM, Do N, Brophy MT, Kim DH, Munshi NC, Driver JA. Contemporary Analysis of Electronic Frailty Measurement in Older Adults with Multiple Myeloma Treated in the National US Veterans Affairs Healthcare System. Cancers (Basel). 2021 Jun 18; 13(12).View Related Profiles.

Orkaby, Ariela
Gaziano, J. Michael
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.

PMID: 34207459; PMCID: PMC8233717; DOI: 10.3390/cancers13123053;

Cheng D, DuMontier C, Yildirim C, Charest B, Hawley CE, Zhuo M, Paik JM, Yaksic E, Gaziano JM, Do N, Brophy M, Cho K, Kim DH, Driver JA, Fillmore NR, Orkaby AR. Updating and Validating the U.S. Veterans Affairs Frailty Index: Transitioning From ICD-9 to ICD-10. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):1318-1325.View Related Profiles.

Orkaby, Ariela
Hawley, Chelsea
Gaziano, J. Michael
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 33693638; PMCID: PMC8202143; DOI: 10.1093/gerona/glab071;

Fillmore NR, La J, Szalat RE, Tuck DP, Nguyen V, Yildirim C, Do NV, Brophy MT, Munshi NC. Prevalence and Outcome of COVID-19 Infection in Cancer Patients: A National Veterans Affairs Study. J Natl Cancer Inst. 2021 06 01; 113(6):691-698.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.
Szalat, Raphael

PMID: 33031532; PMCID: PMC7665587; DOI: 10.1093/jnci/djaa159;

Bigdeli TB, Fanous AH, Li Y, Rajeevan N, Sayward F, Genovese G, Gupta R, Radhakrishnan K, Malhotra AK, Sun N, Lu Q, Hu Y, Li B, Chen Q, Mane S, Miller P, Cheung KH, Gur RE, Greenwood TA, Braff DL, Achtyes ED, Buckley PF, Escamilla MA, Lehrer D, Malaspina DP, McCarroll SA, Rapaport MH, Vawter MP, Pato MT, Pato CN, Zhao H, Kosten TR, Brophy M, Pyarajan S, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, Aslan M, Harvey PD. Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. Schizophr Bull. 2021 03 16; 47(2):517-529.View Related Profiles.

Gaziano, J. Michael
Brophy, Mary

PMID: 33169155; PMCID: PMC7965063; DOI: 10.1093/schbul/sbaa133;

Fillmore NR, Elbers DC, La J, Feldman TC, Sung FC, Hall RB, Nguyen V, Link N, Zwolinski R, Dipietro S, Miller SJ, Aleksanyan A, Goryachev SD, Corcoran P, Bergstrom SJ, Parenteau MA, Sprague RS, Thornton DJ, Driver JA, Strymish JM, Evans S, Colonna B, Brophy MT, Do NV. Corrigendum to: An Application to Support COVID-19 Occupational Health and Patient Tracking at a Veterans Affairs Medical Center. J Am Med Inform Assoc. 2021 03 01; 28(3):673.View Related Profiles.

Elbers, Danne
Thornton, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael

PMID: 33306790; PMCID: PMC7799026; DOI: 10.1093/jamia/ocaa317;

Hartman RI, La J, Chang MS, Cheng D, Do N, Brophy M, Fillmore NR. Risk factors for thick melanoma among veterans: A cross-sectional study. J Am Acad Dermatol. 2021 Jun; 84(6):1766-1769.View Related Profiles.

La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 33422630

Fillmore NR, Elbers DC, La J, Feldman TC, Sung FC, Hall RB, Nguyen V, Link N, Zwolinski R, Dipietro S, Miller SJ, Aleksanyan A, Goryachev SD, Corcoran P, Bergstrom SJ, Parenteau MA, Sprague RS, Thornton DJ, Driver JA, Strymish JM, Evans S, Colonna B, Brophy MT, Do NV. An application to support COVID-19 occupational health and patient tracking at a Veterans Affairs medical center. J Am Med Inform Assoc. 2020 11 01; 27(11):1716-1720.View Related Profiles.

Elbers, Danne
Thornton, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 33067628; PMCID: PMC7665524; DOI: 10.1093/jamia/ocaa162;

La J, Cheng D, Brophy MT, Do NV, Lee JSH, Tuck D, Fillmore NR. Real-World Outcomes for Patients Treated With Immune Checkpoint Inhibitors in the Veterans Affairs System. JCO Clin Cancer Inform. 2020 10; 4:918-928.View Related Profiles.

Tuck, David
La, Jennifer
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 33074743; PMCID: PMC7608595; DOI: 10.1200/CCI.20.00084;

Elbers DC, Fillmore NR, Sung FC, Ganas SS, Prokhorenkov A, Meyer C, Hall RB, Ajjarapu SJ, Chen DC, Meng F, Grossman RL, Brophy MT, Do NV. The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database. Patterns (N Y). 2020 Sep 11; 1(6):100083.View Related Profiles.

Chen, Daniel
Elbers, Danne
Meng, Frank
Brophy, Mary
Fillmore, Nathanael
Ajjarapu, Samuel

PMID: 33205130; PMCID: PMC7660389; DOI: 10.1016/j.patter.2020.100083;

Yellapragada SV, Fillmore NR, Frolov A, Zhou Y, Dev P, Yameen H, Ifeorah C, Do NV, Brophy MT, Munshi NC. Vitamin D deficiency predicts for poor overall survival in white but not African American patients with multiple myeloma. Blood Adv. 2020 04 28; 4(8):1643-1646.View Related Profiles.

Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.

PMID: 32315398; PMCID: PMC7189302; DOI: 10.1182/bloodadvances.2019001411;

Hunter-Zinck H, Shi Y, Li M, Gorman BR, Ji SG, Sun N, Webster T, Liem A, Hsieh P, Devineni P, Karnam P, Gong X, Radhakrishnan L, Schmidt J, Assimes TL, Huang J, Pan C, Humphries D, Brophy M, Moser J, Muralidhar S, Huang GD, Przygodzki R, Concato J, Gaziano JM, Gelernter J, O'Donnell CJ, Hauser ER, Zhao H, O'Leary TJ, Tsao PS, Pyarajan S. Genotyping Array Design and Data Quality Control in the Million Veteran Program. Am J Hum Genet. 2020 04 02; 106(4):535-548.View Related Profiles.

O'Donnell, Christopher
Gaziano, J. Michael
Brophy, Mary

PMID: 32243820; PMCID: PMC7118558; DOI: 10.1016/j.ajhg.2020.03.004;

Addo-Tabiri NO, Chudasama R, Vasudeva R, Leiva O, Garcia B, Ravid JD, Bunze T, Rosen L, Belghasem M, Francis J, Brophy M, Johnson B, Ferguson R, Weinberg J, Chitalia VC. Black Patients Experience Highest Rates of Cancer-associated Venous Thromboembolism. Am J Clin Oncol. 2020 02; 43(2):94-100.View Related Profiles.

Weinberg, Janice
Francis, Jean
Brophy, Mary
Belghasem, Mostafa
Addo-Tabiri, Nana
Chitalia, Vipul

PMID: 31809329; PMCID: PMC9743359; DOI: 10.1097/COC.0000000000000639;

Lin DW, Shih MC, Aronson W, Basler J, Beer TM, Brophy M, Cooperberg M, Garzotto M, Kelly WK, Lee K, McGuire V, Wang Y, Lu Y, Markle V, Nseyo U, Ringer R, Savage SJ, Sinnott P, Uchio E, Yang CC, Montgomery RB. Veterans Affairs Cooperative Studies Program Study #553: Chemotherapy After Prostatectomy for High-risk Prostate Carcinoma: A Phase III Randomized Study. Eur Urol. 2020 05; 77(5):563-572. PMID: 31924316

Harvey PD, Sun N, Bigdeli TB, Fanous AH, Aslan M, Malhotra AK, Lu Q, Hu Y, Li B, Chen Q, Mane S, Miller P, Rajeevan N, Sayward F, Cheung KH, Li Y, Greenwood TA, Gur RE, Braff DL, Brophy M, Pyarajan S, O'Leary TJ, Gleason T, Przygodszki R, Muralidhar S, Gaziano JM, Concato J, Zhao H, Siever LJ. Genome-wide association study of cognitive performance in U.S. veterans with schizophrenia or bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2020 04; 183(3):181-194.View Related Profiles.

Gaziano, J. Michael
Brophy, Mary

PMID: 31872970

Cheng D, Ramos-Cejudo J, Tuck D, Elbers D, Brophy M, Do N, Fillmore N. External validation of a prognostic model for mortality among patients with non-small-cell lung cancer using the Veterans Precision Oncology Data Commons. Semin Oncol. 2019 Aug - Oct; 46(4-5):327-333.View Related Profiles.

Elbers, Danne
Tuck, David
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 31708233; PMCID: PMC11068418; DOI: 10.1053/j.seminoncol.2019.09.006;

Schiller SJ, Shannon C, Brophy MT, Denicoff AM, Good MJ, Prindiville SA, Huang GD. The National Cancer Institute and Department of Veterans Affairs Interagency Group to Accelerate Trials Enrollment (NAVIGATE): A federal collaboration to improve cancer care. Semin Oncol. 2019 Aug - Oct; 46(4-5):308-313. PMID: 31711680

Do N, Grossman R, Feldman T, Fillmore N, Elbers D, Tuck D, Dhond R, Selva L, Meng F, Fitzsimons M, Ajjarapu S, Ayandeh S, Hall R, Do S, Brophy M. The Veterans Precision Oncology Data Commons: Transforming VA data into a national resource for research in precision oncology. Semin Oncol. 2019 Aug - Oct; 46(4-5):314-320.View Related Profiles.

Elbers, Danne
Tuck, David
Meng, Frank
Selva, Luis
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Dhond, Rupali
Ajjarapu, Samuel

PMID: 31629530

Do NV, Ramos JC, Fillmore NR, Grossman RL, Fitzsimons M, Elbers DC, Meng F, Johnson BR, Ajjarapu S, DeDomenico CL, Pierce-Murray KE, Hall RB, Do AF, Gaynor K, Elkin PL, Brophy MT. Machine Learning Methods to Predict Lung Cancer Survival Using the Veterans Affairs Research Precision Oncology Data Commons. Stud Health Technol Inform. 2019 Aug 21; 264:1453.View Related Profiles.

Elbers, Danne
Meng, Frank
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Ajjarapu, Samuel

PMID: 31438177

Fillmore N, Do N, Brophy M, Zimolzak A. Interactive Machine Learning for Laboratory Data Integration. Stud Health Technol Inform. 2019 Aug 21; 264:133-137.View Related Profiles.

Zimolzak, Andrew
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan

PMID: 31437900; PMCID: PMC11166040; DOI: 10.3233/SHTI190198;

Fillmore NR, Yellapragada SV, Ifeorah C, Mehta A, Cirstea D, White PS, Rivero G, Zimolzak A, Pyarajan S, Do N, Brophy M, Munshi NC. With equal access, African American patients have superior survival compared to white patients with multiple myeloma: a VA study. Blood. 2019 06 13; 133(24):2615-2618.View Related Profiles.

Zimolzak, Andrew
Brophy, Mary
Fillmore, Nathanael
Van Do, Nhan
Munshi, Nikhil C.

PMID: 31003998; PMCID: PMC6566591; DOI: 10.1182/blood.2019000406;

Khalil L, McNeil RB, Sims KJ, Felder KA, Hauser ER, Goldstein KM, Voils CI, Klimas NG, Brophy MT, Thomas CM, Whitley RL, Dursa EK, Helmer DA, Provenzale DT. The Gulf War Era Cohort and Biorepository: A Longitudinal Research Resource of Veterans of the 1990-1991 Gulf War Era. Am J Epidemiol. 2018 11 01; 187(11):2279-2291. PMID: 30060060

Timilsina S, Brittan K, O'Dell JR, Brophy M, Davis-Karim A, Henrie AM, Neogi T, Newcomb J, Palevsky PM, Pillinger MH, Pittman D, Taylor TH, Wu H, Mikuls TR. Design and Rationale for the Veterans Affairs "Cooperative Study Program 594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat" Trial. Contemp Clin Trials. 2018 05; 68:102-108.View Related Profiles.

Brophy, Mary
Neogi, Tuhina

PMID: 29597007

Weisbord SD, Gallagher M, Jneid H, Garcia S, Cass A, Thwin SS, Conner TA, Chertow GM, Bhatt DL, Shunk K, Parikh CR, McFalls EO, Brophy M, Ferguson R, Wu H, Androsenko M, Myles J, Kaufman J, Palevsky PM. Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine. N Engl J Med. 2018 02 15; 378(7):603-614.View Related Profiles.

Brophy, Mary
Ferguson, Ryan
Thwin, Soe Soe

PMID: 29130810

Bae E, White P, Brophy M, Lichtman M, Krathen MS, Mahalingam M. Cutaneous Rosai-Dorfman Disease With Linear Lesions and Monoclonal Gammopathy. Am J Dermatopathol. 2017 Oct; 39(10):776-781.View Related Profiles.

Brophy, Mary
Lichtman, Michael

PMID: 28930107

Peper SM, Lew R, Mikuls T, Brophy M, Rybin D, Wu H, O'Dell J. Rheumatoid Arthritis Treatment After Methotrexate: The Durability of Triple Therapy Versus Etanercept. Arthritis Care Res (Hoboken). 2017 Oct; 69(10):1467-1472.View Related Profiles.

Brophy, Mary
Lew, Robert

PMID: 28388820; DOI: 10.1002/acr.23255;

Bansback N, Phibbs CS, Sun H, O'Dell JR, Brophy M, Keystone EC, Leatherman S, Mikuls TR, Anis AH. Triple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis: A Cost-Effectiveness Analysis. Ann Intern Med. 2017 Jul 04; 167(1):8-16.View Related Profiles.

Brophy, Mary
Leatherman, Sarah

PMID: 28554192

Fiore LD, Brophy MT, Ferguson RE, Shannon C, Turek SJ, Pierce-Murray K, Ajjarapu S, Huang GD, Lee C, Lavori PW. Data Sharing, Clinical Trials, and Biomarkers in Precision Oncology: Challenges, Opportunities, and Programs at the Department of Veterans Affairs. Clin Pharmacol Ther. 2017 May; 101(5):586-589.View Related Profiles.

Fiore, Louis
Brophy, Mary
Ferguson, Ryan
Ajjarapu, Samuel

PMID: 28182272; PMCID: PMC5414893; DOI: 10.1002/cpt.660;

Quach LT, Chang BH, Brophy MT, Soe Thwin S, Hannagan K, O'Dell JR. Rheumatoid arthritis triple therapy compared with etanercept: difference in infectious and gastrointestinal adverse events. Rheumatology (Oxford). 2017 Mar 01; 56(3):378-383. PMID: 27994091; PMCID: PMC5850115; DOI: 10.1093/rheumatology/kew412;

Lederle FA, Cushman WC, Ferguson RE, Brophy MT, Fiore Md LD. Chlorthalidone Versus Hydrochlorothiazide: A New Kind of Veterans Affairs Cooperative Study. Ann Intern Med. 2016 11 01; 165(9):663-664.View Related Profiles.

Brophy, Mary
Ferguson, Ryan

PMID: 27538129; DOI: 10.7326/M16-1208;

Fiore LD, Brophy MT, Turek S, Kudesia V, Ramnath N, Shannon C, Ferguson R, Pyarajan S, Fiore MA, Hornberger J, Lavori P. The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine. Biomark Cancer. 2016; 8:9-16.View Related Profiles.

Fiore, Louis
Brophy, Mary
Ferguson, Ryan
Kudesia, Valmeek

PMID: 26949343; PMCID: PMC4772906; DOI: 10.4137/BIC.S37548;

Fiore L, Ferguson RE, Brophy M, Kudesia V, Shannon C, Zimolzak A, Pierce-Murray K, Turek S, Lavori P. Implementation of a Precision Oncology Program as an Exemplar of a Learning Health Care System in the VA. Fed Pract. 2016 Feb; 33(Suppl 1):26S-30S.View Related Profiles.

Fiore, Louis
Brophy, Mary
Ferguson, Ryan

PMID: 30766202; PMCID: PMC6375409

Bansback N, Keystone E, O'Dell J, Phibbs CS, Hannagan K, Brophy M, Anis A. Making smart investment decisions in clinical research. Trials. 2015 Dec 29; 16:590. PMID: 26712327; PMCID: PMC4693420; DOI: 10.1186/s13063-015-1123-1;

Gaziano JM, Concato J, Brophy M, Fiore L, Pyarajan S, Breeling J, Whitbourne S, Deen J, Shannon C, Humphries D, Guarino P, Aslan M, Anderson D, LaFleur R, Hammond T, Schaa K, Moser J, Huang G, Muralidhar S, Przygodzki R, O'Leary TJ. Million Veteran Program: A mega-biobank to study genetic influences on health and disease. J Clin Epidemiol. 2016 Feb; 70:214-23.View Related Profiles.

Gaziano, J. Michael
Fiore, Louis
Brophy, Mary

PMID: 26441289; DOI: 10.1016/j.jclinepi.2015.09.016;

Harvey PD, Siever LJ, Huang GD, Muralidhar S, Zhao H, Miller P, Aslan M, Mane S, McNamara M, Gleason T, Brophy M, Przygodszki R, O'Leary TJ, Gaziano M, Concato J. The genetics of functional disability in schizophrenia and bipolar illness: Methods and initial results for VA cooperative study #572. Am J Med Genet B Neuropsychiatr Genet. 2014 Jun; 165B(4):381-9. PMID: 24798943; DOI: 10.1002/ajmg.b.32242;

Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W, Leehey DJ, McCullough PA, O'Connor T, Palevsky PM, Reilly RF, Seliger SL, Warren SR, Watnick S, Peduzzi P, Guarino P. Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. 2013 Nov 14; 369(20):1892-903. PMID: 24206457; DOI: 10.1056/NEJMoa1303154;

O'Dell JR, Mikuls TR, Taylor TH, Ahluwalia V, Brophy M, Warren SR, Lew RA, Cannella AC, Kunkel G, Phibbs CS, Anis AH, Leatherman S, Keystone E. Therapies for active rheumatoid arthritis after methotrexate failure. N Engl J Med. 2013 Jul 25; 369(4):307-18.View Related Profiles.

Brophy, Mary
Lew, Robert
Leatherman, Sarah

PMID: 23755969; DOI: 10.1056/NEJMoa1303006;

Weisbord SD, Gallagher M, Kaufman J, Cass A, Parikh CR, Chertow GM, Shunk KA, McCullough PA, Fine MJ, Mor MK, Lew RA, Huang GD, Conner TA, Brophy MT, Lee J, Soliva S, Palevsky PM. Prevention of contrast-induced AKI: a review of published trials and the design of the prevention of serious adverse events following angiography (PRESERVE) trial. Clin J Am Soc Nephrol. 2013 Sep; 8(9):1618-31.View Related Profiles.

Kaufman, James
Brophy, Mary
Lew, Robert

PMID: 23660180; PMCID: PMC3805082; DOI: 10.2215/CJN.11161012;

D'Avolio L, Ferguson R, Goryachev S, Woods P, Sabin T, O'Neil J, Conrad C, Gillon J, Escalera J, Brophy M, Lavori P, Fiore L. Implementation of the Department of Veterans Affairs' first point-of-care clinical trial. J Am Med Inform Assoc. 2012 Jun; 19(e1):e170-6.View Related Profiles.

Conrad, Chester
Fiore, Louis
Brophy, Mary
Ferguson, Ryan

PMID: 22366293; PMCID: PMC3392864; DOI: 10.1136/amiajnl-2011-000623;

Munshi NC, Lee S, Kambhampati S, Mohiuddin A, Rose MG, Behler C, Han A, Efebera YA, Houranieh A, Brophy MT, Zimelman A, Prabhala RH, Grady T, Klein CE, Mehta P, Hayes TG, Roodman GD, Lichtenstein A. Efficacy and improved toxicity profile of once a week bortezomib (BZ) with dexamethasone (dex) in newly diagnosed multiple myeloma (NDMM) patients (pts) with older age and comorbidities: Preliminary results of an ongoing clinical study. J Clin Oncol. 2011 May 20; 29(15_suppl):8074. PMID: 28023488

Fiore LD, Brophy M, Ferguson RE, D'Avolio L, Hermos JA, Lew RA, Doros G, Conrad CH, O'Neil JA, Sabin TP, Kaufman J, Swartz SL, Lawler E, Liang MH, Gaziano JM, Lavori PW. A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen. Clin Trials. 2011 Apr; 8(2):183-95.View Related Profiles.

Conrad, Chester
Doros, Gheorghe
Gaziano, J. Michael
Kaufman, James
Hermos, John
Fiore, Louis
Brophy, Mary
Lew, Robert
Ferguson, Ryan

PMID: 21478329; PMCID: PMC3195898; DOI: 10.1177/1740774510395635;

Fried LF, Duckworth W, Zhang JH, O'Connor T, Brophy M, Emanuele N, Huang GD, McCullough PA, Palevsky PM, Seliger S, Warren SR, Peduzzi P. Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D). Clin J Am Soc Nephrol. 2009 Feb; 4(2):361-8. PMID: 19118120; PMCID: PMC2637584; DOI: 10.2215/CJN.03350708;

Montgomery B, Lavori P, Garzotto M, Lee K, Brophy M, Thaneemit-Chen S, Kelly W, Basler J, Ringer R, Yu W, Whittemore A, Lin DW. Veterans Affairs Cooperative Studies Program study 553: Chemotherapy after prostatectomy, a phase III randomized study of prostatectomy versus prostatectomy with adjuvant docetaxel for patients with high-risk, localized prostate cancer. Urology. 2008 Sep; 72(3):474-80. PMID: 18407333; DOI: 10.1016/j.urology.2008.02.050;

Hermos JA, Cohen SA, Hall R, Gagnon DR, Brophy MT, Fiore LD. Association of elevated alanine aminotransferase with BMI and diabetes in older veteran outpatients. Diabetes Res Clin Pract. 2008 Apr; 80(1):153-8.View Related Profiles.

Gagnon, David
Hermos, John
Fiore, Louis
Brophy, Mary

PMID: 18178283; DOI: 10.1016/j.diabres.2007.11.008;

Farwell WR, Scranton RE, Lawler EV, Lew RA, Brophy MT, Fiore LD, Gaziano JM. The association between statins and cancer incidence in a veterans population. J Natl Cancer Inst. 2008 Jan 16; 100(2):134-9.View Related Profiles.

Gaziano, J. Michael
Fiore, Louis
Brophy, Mary
Lew, Robert

PMID: 18182618; DOI: 10.1093/jnci/djm286;

Fincke BG, Snyder K, Cantillon C, Gaehde S, Standring P, Fiore L, Brophy M, Gagnon DR. Three complementary definitions of polypharmacy: methods, application and comparison of findings in a large prescription database. Pharmacoepidemiol Drug Saf. 2005 Feb; 14(2):121-8.View Related Profiles.

Fincke, Benjamin
Gagnon, David
Fiore, Louis
Brophy, Mary
Gaehde, Stephan

PMID: 15386712

Brophy MT, Snyder KE, Gaehde S, Ives C, Gagnon D, Fiore LD. Anticoagulant use for atrial fibrillation in the elderly. J Am Geriatr Soc. 2004 Jul; 52(7):1151-6.View Related Profiles.

Gagnon, David
Fiore, Louis
Brophy, Mary
Gaehde, Stephan

PMID: 15209654

LeBlanc K, Brophy MT. Simvastatin. Ann Intern Med. 2003 Jun 17; 138(12):E1014. PMID: 12809481

Lavori PW, Krause-Steinrauf H, Brophy M, Buxbaum J, Cockroft J, Cox DR, Fiore L, Greely HT, Greenberg H, Holmes EW, Nelson LM, Sugarman J. Principles, organization, and operation of a DNA bank for clinical trials: a Department of Veterans Affairs cooperative study. Control Clin Trials. 2002 Jun; 23(3):222-39.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 12057876

Fiore LD, Ezekowitz MD, Brophy MT, Lu D, Sacco J, Peduzzi P. Department of Veterans Affairs Cooperative Studies Program Clinical Trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results of the CHAMP study. Circulation. 2002 Feb 5; 105(5):557-63.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 11827919

Scola M, Brophy M, Fiore L. Localized consumptive coagulopathy. Circulation. 2001 Jul 3; 104(1):120-1.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 11435349

Fiore LD, Scola MA, Cantillon CE, Brophy MT. Anaphylactoid reactions to vitamin K. J Thromb Thrombolysis. 2001 Apr; 11(2):175-83.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 11406734

O'Regan AW, Brophy MT. Pulmonary Langerhans'-cell histiocytosis. N Engl J Med. 2000 Nov 30; 343(22):1654-6. PMID: 11184985

Cersosimo RJ, Brophy MT. Hiccups with high dose dexamethasone administration: a case report. Cancer. 1998 Jan 15; 82(2):412-4. PMID: 9445200

Winward DB, Brophy MT. Acute renal failure after administration of intravenous immunoglobulin: review of the literature and case report. Pharmacotherapy. 1995 Nov-Dec; 15(6):765-72. PMID: 8602385

Cappelleri JC, Fiore LD, Brophy MT, Deykin D, Lau J. Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis. Am Heart J. 1995 Sep; 130(3 Pt 1):547-52.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 7661074

Brophy MT, Fiore LD, Lau J, Goodwin R, Lopez A, Deykin D. Comparison of a standard and a sensitive thromboplastin in monitoring low intensity oral anticoagulant therapy. Am J Clin Pathol. 1994 Jul; 102(1):134-7.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 8037160

Brophy MT, Fiore LD, Lau J, Headley E, Allen M, Deykin D. A clinical study monitoring low-intensity anticoagulant therapy with a standard-sensitivity thromboplastin. Arch Pathol Lab Med. 1993 Jun; 117(6):618-21.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 8503734

Fiore LD, Brophy MT, Lopez A, Janson P, Deykin D. The bleeding time response to aspirin. Identifying the hyperresponder. Am J Clin Pathol. 1990 Sep; 94(3):292-6.View Related Profiles.

Fiore, Louis
Brophy, Mary

PMID: 2396603

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 123 publications over 27 distinct years, with a maximum of 17 publications in 2024

Bar chart showing 123 publications over 27 distinct years, with a maximum of 17 publications in 2024

Year	Publications
1990	1
1993	1
1994	1
1995	2
1998	1
2000	1
2001	2
2002	2
2003	1
2004	1
2005	1
2008	4
2011	2
2012	1
2013	3
2014	1
2015	2
2016	3
2017	6
2018	2
2019	7
2020	7
2021	13
2022	15
2023	16
2024	17
2025	10

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