Martin Larson | Profiles RNS

Martin G. Larson, SD

Research Professor

Boston University School of Public Health

Biostatistics

SD, Harvard School of Public Health
AB, Harvard University

Martin G. Larson, SD, is a research professor in the department of biostatistics at the Boston University School of Public Health. He also serves as a research associate professor in the field of preventive medicine & epidemiology. He has served as a doctoral advisor and served on multiple committees within the Framingham Heart Study. He is prolific in his field, having published over 500 papers.

Research Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Preventive Medicine & Epidemiology

Primary Investigator
Framingham Heart Study

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Research Professor
Boston University
Mathematics and Statistics

BU Research

Trans-omics Analysis to Unravel Molecular Underpinnings of Heart, Lung and Blood Disease Risk Factors
05/01/2018 - 04/30/2020 (Subcontract PI)
University of Texas, Houston NIH NHLBI
5R01HL142003-02

Extracellular RNAs: Biomarkers for Cardivascular Risk and Disease
08/01/2015 - 07/31/2019 (Subcontract PI)
University of Massachusetts, Worcester NIH NCATS
5UH3TR000921-05

Metabolic Profiling of Exercise to Predict Cardiometabolic Risk
07/01/2015 - 06/30/2019 (Subcontract PI)
Massachusetts General Hospital American Heart Assoc

Chronic Inflammation, Cardiovascular Aging, and Longevity
02/01/2015 - 01/31/2017 (Subcontract PI)
The Brigham and Women's Hospital, Inc. American Heart Assoc

FHS SABRE Project: A Biomarker Discovery Study for Metabolic Syndrome Risk Factors Atheroscerotic Cardiovascular Disease
08/01/2008 - 01/07/2014 (PI)
BG Medicine, Inc.

SCCOR: Project 1 Variance Affecting Hypertension and its Consequences
02/23/2001 - 01/31/2006 (PI)
Yale University NIH NHLBI

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Mitchell GF, Rong J, Larson MG, Korzinski TJ, Xanthakis V, Sigurdsson S, Gudnason V, Launer LJ, Aspelund T, Hamburg NM, Gotal JD, Vasan RS. Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach: The AI-VascularAge Model. Hypertension. 2023 Oct 30.View Related Profiles.

Larson, Martin
Hamburg, Naomi
Xanthakis, Vanessa

PMID: 37901957

Feofanova EV, Brown MR, Alkis T, Manuel AM, Li X, Tahir UA, Li Z, Mendez KM, Kelly RS, Qi Q, Chen H, Larson MG, Lemaitre RN, Morrison AC, Grieser C, Wong KE, Gerszten RE, Zhao Z, Lasky-Su J, Yu B. Author Correction: Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations. Nat Commun. 2023 Oct 19; 14(1):6611. PMID: 37857625; PMCID: PMC10587143; DOI: 10.1038/s41467-023-42472-3;

Nayor M, Gajjar P, Miller P, Murthy VL, Shah RV, Houstis NE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD, Mitchell GF. Arterial Stiffness and Cardiorespiratory Fitness Impairment in the Community. J Am Heart Assoc. 2023 Nov 07; 12(21):e029619.View Related Profiles.

Larson, Martin
Nayor, Matthew
Velagaleti, Raghava

PMID: 37850464

Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of healthy dietary patterns and cardiorespiratory fitness in the community. Eur J Prev Cardiol. 2023 Oct 10; 30(14):1450-1461.View Related Profiles.

Larson, Martin
Nayor, Matthew
Walker, Maura
Xanthakis, Vanessa

PMID: 37164358; PMCID: PMC10562138; DOI: 10.1093/eurjpc/zwad113;

Ngo D, Pratte KA, Flexeder C, Petersen H, Dang H, Ma Y, Keyes MJ, Gao Y, Deng S, Peterson BD, Farrell LA, Bhambhani VM, Palacios C, Quadir J, Gillenwater L, Xu H, Emson C, Gieger C, Suhre K, Graumann J, Jain D, Conomos MP, Tracy RP, Guo X, Liu Y, Johnson WC, Cornell E, Durda P, Taylor KD, Papanicolaou GJ, Rich SS, Rotter JI, Rennard SI, Curtis JL, Woodruff PG, Comellas AP, Silverman EK, Crapo JD, Larson MG, Vasan RS, Wang TJ, Correa A, Sims M, Wilson JG, Gerszten RE, O'Connor GT, Barr RG, Couper D, Dupuis J, Manichaikul A, O'Neal WK, Tesfaigzi Y, Schulz H, Bowler RP. Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts. Ann Am Thorac Soc. 2023 Aug; 20(8):1124-1135.View Related Profiles.

O'Connor, George
Dupuis, Josee
Larson, Martin

PMID: 37351609; PMCID: PMC10405603; DOI: 10.1513/AnnalsATS.202210-857OC;

Brant LCC, Ribeiro AH, Pinto-Filho MM, Kornej J, Preis SR, Fetterman JL, Eromosele OB, Magnani JW, Murabito JM, Larson MG, Benjamin EJ, Ribeiro ALP, Lin H. Association Between Electrocardiographic Age and Cardiovascular Events in Community Settings: The Framingham Heart Study. Circ Cardiovasc Qual Outcomes. 2023 Jul; 16(7):e009821.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Fetterman, Jessica
Murabito, Joanne
Larson, Martin
Preis, Sarah

PMID: 37381910; PMCID: PMC10524985; DOI: 10.1161/CIRCOUTCOMES.122.009821;

Mitchell GF, Rong J, Larson MG, Cooper LL, Xanthakis V, Benjamin EJ, Hamburg NM, Vasan RS. Longitudinal Hemodynamic Correlates of and Sex Differences in the Evolution of Blood Pressure Across the Adult Lifespan: The Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e027329.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Xanthakis, Vanessa

PMID: 37318016; PMCID: PMC10356050; DOI: 10.1161/JAHA.122.027329;

Li Y, Gray A, Xue L, Farb MG, Ayalon N, Andersson C, Ko D, Benjamin EJ, Levy D, Vasan RS, Larson MG, Rong J, Xanthakis V, Liu C, Fetterman JL, Gopal DM. Metabolomic Profiles, Ideal Cardiovascular Health, and Risk of Heart Failure and Atrial Fibrillation: Insights From the Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e028022.View Related Profiles.

Ko, Darae
Gopal, Deepa
Benjamin, Emelia
Fetterman, Jessica
Larson, Martin
Farb, Melissa
Ayalon, Nir
Xanthakis, Vanessa

PMID: 37301766; PMCID: PMC10356055; DOI: 10.1161/JAHA.122.028022;

Feofanova EV, Brown MR, Alkis T, Manuel AM, Li X, Tahir UA, Li Z, Mendez KM, Kelly RS, Qi Q, Chen H, Larson MG, Lemaitre RN, Morrison AC, Grieser C, Wong KE, Gersztern RE, Zhao Z, Lasky-Su J, Yu B. Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations. Nat Commun. 2023 May 30; 14(1):3111. PMID: 37253714; PMCID: PMC10229598; DOI: 10.1038/s41467-023-38800-2;

Lin H, Kwan AC, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Salto G, Mitchell GF, Larson MG, Vasan RS, Cheng S. Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography. Sci Rep. 2023 Apr 08; 13(1):5786.View Related Profiles.

Lin, Honghuang
Larson, Martin
Xanthakis, Vanessa

PMID: 37031215; PMCID: PMC10082757; DOI: 10.1038/s41598-023-32577-6;

Showing 10 of 621 results. Show More

Suthahar N, Wang D, Aboumsallem JP, Shi C, de Wit S, Liu EE, Lau ES, Bakker SJL, Gansevoort RT, van der Vegt B, Jovani M, Kreger BE, Lee Splansky G, Benjamin EJ, Vasan RS, Larson MG, Levy D, Ho JE, de Boer RA. Association of Initial and Longitudinal Changes in C-reactive Protein With the Risk of Cardiovascular Disease, Cancer, and Mortality. Mayo Clin Proc. 2023 Apr; 98(4):549-558.View Related Profiles.

Benjamin, Emelia
Larson, Martin

PMID: 37019514

Taylor CN, Wang D, Larson MG, Lau ES, Benjamin EJ, D'Agostino RB, Vasan RS, Levy D, Cheng S, Ho JE. Family History of Modifiable Risk Factors and Association With Future Cardiovascular Disease. J Am Heart Assoc. 2023 Mar 21; 12(6):e027881.View Related Profiles.

Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph

PMID: 36892090; PMCID: PMC10111537; DOI: 10.1161/JAHA.122.027881;

Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of Healthy Dietary Patterns and Cardiorespiratory Fitness in the Community. medRxiv. 2023 Feb 10.View Related Profiles.

Larson, Martin
Nayor, Matthew
Xanthakis, Vanessa

PMID: 36798343; PMCID: PMC9934801; DOI: 10.1101/2023.02.09.23285714;

Sarma AA, Paniagua SM, Lau ES, Wang D, Liu EE, Larson MG, Hamburg NM, Mitchell GF, Kizer J, Psaty BM, Allen NB, Lely AT, Gansevoort RT, Rosenberg E, Mukamal K, Benjamin EJ, Vasan RS, Cheng S, Levy D, Boer RA, Gottdiener JS, Shah SJ, Ho JE. Multiple Prior Live Births Are Associated With Cardiac Remodeling and Heart Failure Risk in Women. J Card Fail. 2023 Jul; 29(7):1032-1042.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi

PMID: 36638956; PMCID: PMC10333450; DOI: 10.1016/j.cardfail.2022.12.014;

Paluch AE, Bajpai S, Ballin M, Bassett DR, Buford TW, Carnethon MR, Chernofsky A, Dooley EE, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kong L, Kraus WE, Larson MG, Lee IM, Matthews CE, Newton RL, Nordström A, Nordström P, Palta P, Patel AV, Pettee Gabriel K, Pieper CF, Pompeii L, Rees-Punia E, Spartano NL, Vasan RS, Whincup PH, Yang S, Fulton JE. Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis. Circulation. 2023 Jan 10; 147(2):122-131.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 36537288; PMCID: PMC9839547; DOI: 10.1161/CIRCULATIONAHA.122.061288;

Spetko N, Rong J, Larson MG, Haidar M, Raber I, Peters K, Benjamin EJ, O'Donnell CJ, Manning WJ, Vasan RS, Mitchell GF, Tsao CW. Cross-Sectional Relationships of Proximal Aortic Stiffness and Left Ventricular Diastolic Function in Adults in the Community. J Am Heart Assoc. 2022 Dec 20; 11(24):e027230.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin

PMID: 36533620; PMCID: PMC9798804; DOI: 10.1161/JAHA.122.027230;

Takvorian KS, Wang D, Courchesne P, Vasan RS, Benjamin EJ, Cheng S, Larson MG, Levy D, Ho JE. The Association of Protein Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. Circ Heart Fail. 2023 Jan; 16(1):e009446.View Related Profiles.

Benjamin, Emelia
Larson, Martin

PMID: 36475777; PMCID: PMC9937440; DOI: 10.1161/CIRCHEARTFAILURE.121.009446;

Nayor M, Gajjar P, Murthy VL, Miller PE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD, Mitchell GF, Shah RV. Blood Pressure Responses During Exercise: Physiological Correlates and Clinical Implications. Arterioscler Thromb Vasc Biol. 2023 Jan; 43(1):163-173.View Related Profiles.

Larson, Martin
Nayor, Matthew
Velagaleti, Raghava

PMID: 36384270; PMCID: PMC9780190; DOI: 10.1161/ATVBAHA.122.318512;

Tromp J, Bauer D, Claggett BL, Frost M, Iversen MB, Prasad N, Petrie MC, Larson MG, Ezekowitz JA, Solomon SD. A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram. Nat Commun. 2022 Nov 09; 13(1):6776. PMID: 36351912; PMCID: PMC9646849; DOI: 10.1038/s41467-022-34245-1;

Cooper LL, Rong J, Maillard P, Beiser A, Hamburg NM, Larson MG, DeCarli C, Vasan RS, Seshadri S, Mitchell GF. Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study. Front Cardiovasc Med. 2022; 9:1013876.View Related Profiles.

Beiser, Alexa
Larson, Martin
Hamburg, Naomi
Seshadri, Sudha

PMID: 36386360; PMCID: PMC9663798; DOI: 10.3389/fcvm.2022.1013876;

Gonzalez Izundegui D, Miller PE, Shah RV, Clish CB, Walker ME, Mitchell GF, Gerszten RE, Larson MG, Vasan RS, Nayor M. Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community. Cardiovasc Diabetol. 2022 Oct 15; 21(1):213.View Related Profiles.

Izundegui, Daniel
Larson, Martin
Nayor, Matthew
Walker, Maura

PMID: 36243866; PMCID: PMC9568897; DOI: 10.1186/s12933-022-01647-w;

Shah RV, Miller P, Colangelo LA, Chernofsky A, Houstis NE, Malhotra R, Velagaleti RS, Jacobs DR, Gabriel KP, Reis JP, Lloyd-Jones DM, Clish CB, Larson MG, Vasan RS, Murthy VL, Lewis GD, Nayor M. Blood-Based Fingerprint of Cardiorespiratory Fitness and Long-Term Health Outcomes in Young Adulthood. J Am Heart Assoc. 2022 Sep 20; 11(18):e026670.View Related Profiles.

Larson, Martin
Nayor, Matthew
Velagaleti, Raghava

PMID: 36073631; PMCID: PMC9683648; DOI: 10.1161/JAHA.122.026670;

McNeill J, Chernofsky A, Nayor M, Rahaghi FN, San Jose Estepar R, Washko G, Synn A, Vasan RS, O'Connor G, Larson MG, Ho JE, Lewis GD. The association of lung function and pulmonary vasculature volume with cardiorespiratory fitness in the community. Eur Respir J. 2022 Aug; 60(2).View Related Profiles.

O'Connor, George
Larson, Martin
Nayor, Matthew

PMID: 34996832; PMCID: PMC9259762; DOI: 10.1183/13993003.01821-2021;

Jovani M, Liu EE, Paniagua SM, Lau ES, Li SX, Takvorian KS, Kreger BE, Splansky GL, de Boer RA, Joshi AD, Hwang SJ, Yao C, Huan T, Courchesne P, Larson MG, Levy D, Chan AT, Ho JE. Cardiovascular disease related circulating biomarkers and cancer incidence and mortality: is there an association? Cardiovasc Res. 2022 Jul 27; 118(10):2317-2328.View Related Profiles.

Larson, Martin
Hwang, Shih-Jen

PMID: 34469519; PMCID: PMC9328284; DOI: 10.1093/cvr/cvab282;

Cooper LL, O'Donnell A, Beiser AS, Thibault EG, Sanchez JS, Benjamin EJ, Hamburg NM, Vasan RS, Larson MG, Johnson KA, Mitchell GF, Seshadri S. Association of Aortic Stiffness and Pressure Pulsatility With Global Amyloid-ß and Regional Tau Burden Among Framingham Heart Study Participants Without Dementia. JAMA Neurol. 2022 Jul 01; 79(7):710-719.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Seshadri, Sudha

PMID: 35666520; PMCID: PMC9171656; DOI: 10.1001/jamaneurol.2022.1261;

Henglin M, Claggett BL, Antonelli J, Alotaibi M, Magalang GA, Watrous JD, Lagerborg KA, Ovsak G, Musso G, Demler OV, Vasan RS, Larson MG, Jain M, Cheng S. Quantitative Comparison of Statistical Methods for Analyzing Human Metabolomics Data. Metabolites. 2022 Jun 04; 12(6). PMID: 35736452; PMCID: PMC9227835; DOI: 10.3390/metabo12060519;

Nayor M, Chernofsky A, Miller PE, Spartano NL, Murthy VL, Malhotra R, Houstis NE, Murabito JM, Clish CB, Larson MG, Vasan RS, Shah RV, Lewis GD. Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness. Circ Genom Precis Med. 2022 Jun; 15(3):e003592.View Related Profiles.

Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole

PMID: 35536222; PMCID: PMC9233103; DOI: 10.1161/CIRCGEN.121.003592;

Liu EE, Suthahar N, Paniagua SM, Wang D, Lau ES, Li SX, Jovani M, Takvorian KS, Kreger BE, Benjamin EJ, Meijers WC, Bakker SJL, Kieneker LM, Gruppen EG, van der Vegt B, de Bock GH, Gansevoort RT, Hussain SK, Hoffmann U, Splansky GL, Vasan RS, Larson MG, Levy D, Cheng S, de Boer RA, Ho JE. Association of Cardiometabolic Disease With Cancer in the Community. JACC CardioOncol. 2022 Mar; 4(1):69-81.View Related Profiles.

Benjamin, Emelia
Larson, Martin

PMID: 35492825; PMCID: PMC9040108; DOI: 10.1016/j.jaccao.2022.01.095;

Paluch AE, Bajpai S, Bassett DR, Carnethon MR, Ekelund U, Evenson KR, Galuska DA, Jefferis BJ, Kraus WE, Lee IM, Matthews CE, Omura JD, Patel AV, Pieper CF, Rees-Punia E, Dallmeier D, Klenk J, Whincup PH, Dooley EE, Pettee Gabriel K, Palta P, Pompeii LA, Chernofsky A, Larson MG, Vasan RS, Spartano N, Ballin M, Nordström P, Nordström A, Anderssen SA, Hansen BH, Cochrane JA, Dwyer T, Wang J, Ferrucci L, Liu F, Schrack J, Urbanek J, Saint-Maurice PF, Yamamoto N, Yoshitake Y, Newton RL, Yang S, Shiroma EJ, Fulton JE. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public Health. 2022 03; 7(3):e219-e228.View Related Profiles.

Dallmeier Rojas, Dhayana
Larson, Martin
Spartano, Nicole

PMID: 35247352; PMCID: PMC9289978; DOI: 10.1016/S2468-2667(21)00302-9;

Vasan RS, Pan S, Xanthakis V, Beiser A, Larson MG, Seshadri S, Mitchell GF. Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study. Hypertension. 2022 May; 79(5):1045-1056.View Related Profiles.

Beiser, Alexa
Larson, Martin
Seshadri, Sudha
Xanthakis, Vanessa

PMID: 35168368; PMCID: PMC9009137; DOI: 10.1161/HYPERTENSIONAHA.121.18776;

Conner SC, Beiser A, Benjamin EJ, LaValley MP, Larson MG, Trinquart L. A comparison of statistical methods to predict the residual lifetime risk. Eur J Epidemiol. 2022 Feb; 37(2):173-194.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Trinquart, Ludovic
Larson, Martin
LaValley, Michael

PMID: 34978669; PMCID: PMC8960348; DOI: 10.1007/s10654-021-00815-8;

Trethewey RE, Spartano NL, Vasan RS, Larson MG, O'Connor GT, Esliger DW, Petherick ES, Steiner MC. Body mass index across adulthood and the development of airflow obstruction and emphysema. Chron Respir Dis. 2022; 19:14799731221139294.View Related Profiles.

O'Connor, George
Larson, Martin
Spartano, Nicole

PMID: 36351077; PMCID: PMC9661572; DOI: 10.1177/14799731221139294;

Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano NL, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey PC, Wijndaele K, Anderssen SA, Lee IM, Ekelund U. Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. Br J Sports Med. 2022 Jul; 56(13):725-732.View Related Profiles.

Larson, Martin
Spartano, Nicole

PMID: 34876405; PMCID: PMC9209690; DOI: 10.1136/bjsports-2021-104827;

Malhotra R, Nicholson CJ, Wang D, Bhambhani V, Paniagua S, Slocum C, Sigurslid HH, Lino Cardenas CL, Li R, Boerboom SL, Chen YC, Hwang SJ, Yao C, Ichinose F, Bloch DB, Lindsay ME, Lewis GD, Aragam JR, Hoffmann U, Mitchell GF, Hamburg NM, Vasan RS, Benjamin EJ, Larson MG, Zapol WM, Cheng S, Roh JD, O'Donnell CJ, Nguyen C, Levy D, Ho JE. Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction. Arterioscler Thromb Vasc Biol. 2022 02; 42(2):e61-e73.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Hamburg, Naomi
Hwang, Shih-Jen

PMID: 34809448; PMCID: PMC8792238; DOI: 10.1161/ATVBAHA.121.316664;

Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575.View Related Profiles.

Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole
Velagaleti, Raghava

PMID: 34436560; PMCID: PMC8633734; DOI: 10.1093/eurheartj/ehab580;

Vasan RS, Pan S, Larson MG, Mitchell GF, Xanthakis V. Arteriosclerosis, Atherosclerosis, and Cardiovascular Health: Joint Relations to the Incidence of Cardiovascular Disease. Hypertension. 2021 11; 78(5):1232-1240.View Related Profiles.

Larson, Martin
Xanthakis, Vanessa

PMID: 34601961; PMCID: PMC8516717; DOI: 10.1161/HYPERTENSIONAHA.121.18075;

Sun X, Ho JE, Gao H, Evangelou E, Yao C, Huan T, Hwang SJ, Courchesne P, Larson MG, Levy D, Ma J, Liu C. Associations of Alcohol Consumption with Cardiovascular Disease-Related Proteomic Biomarkers: The Framingham Heart Study. J Nutr. 2021 09 04; 151(9):2574-2582.View Related Profiles.

Liu, Chunyu
Larson, Martin
Hwang, Shih-Jen

PMID: 34159370; PMCID: PMC8417922; DOI: 10.1093/jn/nxab186;

Nayor M, Shah RV, Tanguay M, Blodgett JB, Chernofsky A, Miller PE, Xanthakis V, Malhotra R, Houstis NE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD. Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample. Am J Cardiol. 2021 10 15; 157:56-63.View Related Profiles.

Larson, Martin
Nayor, Matthew
Velagaleti, Raghava
Xanthakis, Vanessa

PMID: 34391575; PMCID: PMC9252421; DOI: 10.1016/j.amjcard.2021.07.020;

Cooper LL, Rong J, Larson MG, Benjamin EJ, Hamburg NM, Vasan RS, Mitchell GF. Discrepancies in Observed and Predicted Longitudinal Change in Central Hemodynamic Measures: The Framingham Heart Study. Hypertension. 2021 09; 78(4):973-982.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Hamburg, Naomi

PMID: 34365810

Lau ES, Paniagua SM, Zarbafian S, Hoffman U, Long MT, Hwang SJ, Courchesne P, Yao C, Ma J, Larson MG, Levy D, Shah RV, Ho JE. Cardiovascular Biomarkers of Obesity and Overlap With Cardiometabolic Dysfunction. J Am Heart Assoc. 2021 07 20; 10(14):e020215.View Related Profiles.

Larson, Martin
Long, Michelle
Hwang, Shih-Jen

PMID: 34219465; PMCID: PMC8483498; DOI: 10.1161/JAHA.120.020215;

Cooper LL, Wang N, Beiser AS, Romero JR, Aparicio HJ, Lioutas VA, Benjamin EJ, Larson MG, Vasan RS, Mitchell GF, Seshadri S, Hamburg NM. Digital Peripheral Arterial Tonometry and Cardiovascular Disease Events: The Framingham Heart Study. Stroke. 2021 08; 52(9):2866-2873.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Aparicio, Hugo
Larson, Martin
Hamburg, Naomi
Seshadri, Sudha

PMID: 34192894; PMCID: PMC8378441; DOI: 10.1161/STROKEAHA.120.031102;

Shah RV, Schoenike MW, Armengol de la Hoz MÁ, Cunningham TF, Blodgett JB, Tanguay M, Sbarbaro JA, Nayor M, Rouvina J, Kowal A, Houstis N, Baggish AL, Ho JE, Hardin C, Malhotra R, Larson MG, Vasan RS, Lewis GD. Metabolic Cost of Exercise Initiation in Patients With Heart Failure With Preserved Ejection Fraction vs Community-Dwelling Adults. JAMA Cardiol. 2021 06 01; 6(6):653-660.View Related Profiles.

Larson, Martin
Nayor, Matthew

PMID: 33729454; PMCID: PMC7970388; DOI: 10.1001/jamacardio.2021.0292;

Katz DH, Tahir UA, Ngo D, Benson MD, Gao Y, Shi X, Nayor M, Keyes MJ, Larson MG, Hall ME, Correa A, Sinha S, Shen D, Herzig M, Yang Q, Robbins JM, Chen ZZ, Cruz DE, Peterson B, Vasan RS, Wang TJ, Wilson JG, Gerszten RE. Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults. Circ Genom Precis Med. 2021 06; 14(3):e003191.View Related Profiles.

Larson, Martin
Nayor, Matthew
Yang, Qiong

PMID: 34019435; PMCID: PMC8497179; DOI: 10.1161/CIRCGEN.120.003191;

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O'Donnell, Christopher
Liu, Chunyu
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Lin H, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Kwan AC, Mitchell GF, Larson MG, Vasan RS, Cheng S. Shared Genetic and Environmental Architecture of Cardiac Phenotypes Assessed via Echocardiography: The Framingham Heart Study. Circ Genom Precis Med. 2021 04; 14(2):e003244.View Related Profiles.

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Tromp J, Paniagua SMA, Lau ES, Allen NB, Blaha MJ, Gansevoort RT, Hillege HL, Lee DE, Levy D, Vasan RS, van der Harst P, van Gilst WH, Larson MG, Shah SJ, de Boer RA, Lam CSP, Ho JE. Age dependent associations of risk factors with heart failure: pooled population based cohort study. BMJ. 2021 03 23; 372:n461.View Related Profiles.

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Lau ES, Paniagua SM, Liu E, Jovani M, Li SX, Takvorian K, Suthahar N, Cheng S, Splansky GL, Januzzi JL, Wang TJ, Vasan RS, Kreger B, Larson MG, Levy D, de Boer RA, Ho JE. Cardiovascular Risk Factors are Associated with Future Cancer. JACC CardioOncol. 2021 Mar; 3(1):48-58. PMID: 33870217; PMCID: PMC8045786; DOI: 10.1016/j.jaccao.2020.12.003;

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O'Donnell, Christopher
Liu, Chunyu
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Larson, Martin
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PMID: 33230300; PMCID: PMC7610439; DOI: 10.1038/s41588-020-00713-x;

Hoekstra M, Chen HY, Rong J, Dufresne L, Yao J, Guo X, Tsai MY, Tsimikas S, Post WS, Vasan RS, Rotter JI, Larson MG, Thanassoulis G, Engert JC. Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):458-464. PMID: 33115273; PMCID: PMC7769958; DOI: 10.1161/ATVBAHA.120.314965;

Echouffo-Tcheugui JB, Niiranen TJ, McCabe EL, Henglin M, Jain M, Vasan RS, Larson MG, Cheng S. An Early-Onset Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study. Diabetes Care. 2020 12; 43(12):3086-3093. PMID: 33033069; PMCID: PMC7770277; DOI: 10.2337/dc19-1758;

Palmu J, Watrous JD, Mercader K, Havulinna AS, Lagerborg KA, Salosensaari A, Inouye M, Larson MG, Rong J, Vasan RS, Lahti L, Andres A, Cheng S, Jousilahti P, Salomaa V, Jain M, Niiranen TJ. Eicosanoid Inflammatory Mediators Are Robustly Associated With Blood Pressure in the General Population. J Am Heart Assoc. 2020 10 20; 9(19):e017598. PMID: 32975162; PMCID: PMC7792391; DOI: 10.1161/JAHA.120.017598;

Suthahar N, Lau ES, Blaha MJ, Paniagua SM, Larson MG, Psaty BM, Benjamin EJ, Allison MA, Bartz TM, Januzzi JL, Levy D, Meems LMG, Bakker SJL, Lima JAC, Cushman M, Lee DS, Wang TJ, deFilippi CR, Herrington DM, Nayor M, Vasan RS, Gardin JM, Kizer JR, Bertoni AG, Allen NB, Gansevoort RT, Shah SJ, Gottdiener JS, Ho JE, de Boer RA. Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure. J Am Coll Cardiol. 2020 09 22; 76(12):1455-1465.View Related Profiles.

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PMID: 32943164; PMCID: PMC7493711; DOI: 10.1016/j.jacc.2020.07.044;

Ngo D, Wen D, Gao Y, Keyes MJ, Drury ER, Katz DH, Benson MD, Sinha S, Shen D, Farrell LA, Peterson BD, Friedman DJ, Elmariah S, Young BA, Smith JG, Yang Q, Vasan RS, Larson MG, Correa A, Humphreys BD, Wang TJ, Pollak MR, Wilson JG, Gerszten RE, Rhee EP. Circulating testican-2 is a podocyte-derived marker of kidney health. Proc Natl Acad Sci U S A. 2020 10 06; 117(40):25026-25035.View Related Profiles.

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Nayor M, Shah RV, Miller PE, Blodgett JB, Tanguay M, Pico AR, Murthy VL, Malhotra R, Houstis NE, Deik A, Pierce KA, Bullock K, Dailey L, Velagaleti RS, Moore SA, Ho JE, Baggish AL, Clish CB, Larson MG, Vasan RS, Lewis GD. Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community. Circulation. 2020 11 17; 142(20):1905-1924.View Related Profiles.

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Andersson C, Liu C, Cheng S, Wang TJ, Gerszten RE, Larson MG, Vasan RS. Metabolomic signatures of cardiac remodelling and heart failure risk in the community. ESC Heart Fail. 2020 Dec; 7(6):3707-3715.View Related Profiles.

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Afshar M, Rong J, Zhan Y, Chen HY, Engert JC, Sniderman AD, Larson MG, Vasan RS, Thanassoulis G. Risks of Incident Cardiovascular Disease Associated With Concomitant Elevations in Lipoprotein(a) and Low-Density Lipoprotein Cholesterol-The Framingham Heart Study. J Am Heart Assoc. 2020 09 15; 9(18):e014711. PMID: 32892691; PMCID: PMC7726982; DOI: 10.1161/JAHA.119.014711;

Velagaleti RS, Larson MG, Enserro D, Song RJ, Vasan RS. Clinical course after a first episode of heart failure: insights from the Framingham Heart Study. Eur J Heart Fail. 2020 10; 22(10):1768-1776.View Related Profiles.

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Chen HY, Cairns BJ, Small AM, Burr HA, Ambikkumar A, Martinsson A, Thériault S, Munter HM, Steffen B, Zhang R, Levinson RT, Shaffer CM, Rong J, Sonestedt E, Dufresne L, Ljungberg J, Näslund U, Johansson B, Ranatunga DK, Whitmer RA, Budoff MJ, Nguyen A, Vasan RS, Larson MG, Harris WS, Damrauer SM, Stark KD, Boekholdt SM, Wareham NJ, Pibarot P, Arsenault BJ, Mathieu P, Gudnason V, O'Donnell CJ, Rotter JI, Tsai MY, Post WS, Clarke R, Söderberg S, Bossé Y, Wells QS, Smith JG, Rader DJ, Lathrop M, Engert JC, Thanassoulis G. Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis. JAMA Cardiol. 2020 06 01; 5(6):694-702.View Related Profiles.

O'Donnell, Christopher
Larson, Martin

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Nayor M, Short MI, Rasheed H, Lin H, Jonasson C, Yang Q, Hveem K, Felix JF, Morrison AC, Wild PS, Morley MP, Cappola TP, Benson MD, Ngo D, Sinha S, Keyes MJ, Shen D, Wang TJ, Larson MG, Brumpton BM, Gerszten RE, Omland T, Vasan RS. Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits. Circ Heart Fail. 2020 05; 13(5):e006749.View Related Profiles.

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Nayor M, Xanthakis V, Tanguay M, Blodgett JB, Shah RV, Schoenike M, Sbarbaro J, Farrell R, Malhotra R, Houstis NE, Velagaleti RS, Moore SA, Baggish AL, O'Connor GT, Ho JE, Larson MG, Vasan RS, Lewis GD. Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function. Circ Heart Fail. 2020 05; 13(5):e006729.View Related Profiles.

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Velagaleti RS, Short MI, Larson MG, Vasan RS. Prognosis of "pre-heart failure" clinical phenotypes. PLoS One. 2020; 15(4):e0231254.View Related Profiles.

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Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, Polfus LM, Benjamin EJ, Bis JC, Bowler R, Cade BE, Choi WJ, Comellas AP, Correa A, Cruz P, Doddapaneni H, Durda P, Gogarten SM, Jain D, Kim RW, Kral BG, Lange LA, Larson MG, Laurie C, Lee J, Lee S, Lewis JP, Metcalf GA, Mitchell BD, Momin Z, Muzny DM, Pankratz N, Park CJ, Rich SS, Rotter JI, Ryan K, Seo D, Tracy RP, Viaud-Martinez KA, Yanek LR, Zhao LP, Lin X, Li B, Li Y, Dupuis J, Reiner AP, Mohlke KL, Auer PL. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. Am J Hum Genet. 2020 01 02; 106(1):112-120.View Related Profiles.

Wang, Biqi
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Yin X, Willinger CM, Keefe J, Liu J, Fernández-Ortiz A, Ibáñez B, Peñalvo J, Adourian A, Chen G, Corella D, Pamplona R, Portero-Otin M, Jove M, Courchesne P, van Duijn CM, Fuster V, Ordovás JM, Demirkan A, Larson MG, Levy D. Lipidomic profiling identifies signatures of metabolic risk. EBioMedicine. 2020 Jan; 51:102520. PMID: 31877415; PMCID: PMC6938899; DOI: 10.1016/j.ebiom.2019.10.046;

Andersson C, Lin H, Liu C, Levy D, Mitchell GF, Larson MG, Vasan RS. Integrated Multiomics Approach to Identify Genetic Underpinnings of Heart Failure and Its Echocardiographic Precursors: Framingham Heart Study. Circ Genom Precis Med. 2019 12; 12(12):e002489.View Related Profiles.

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Gómez-Banoy N, Guseh JS, Li G, Rubio-Navarro A, Chen T, Poirier B, Putzel G, Rosselot C, Pabón MA, Camporez JP, Bhambhani V, Hwang SJ, Yao C, Perry RJ, Mukherjee S, Larson MG, Levy D, Dow LE, Shulman GI, Dephoure N, Garcia-Ocana A, Hao M, Spiegelman BM, Ho JE, Lo JC. Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans. Nat Med. 2019 11; 25(11):1739-1747.View Related Profiles.

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Lau ES, Paniagua SM, Guseh JS, Bhambhani V, Zanni MV, Courchesne P, Lyass A, Larson MG, Levy D, Ho JE. Sex Differences in Circulating Biomarkers of Cardiovascular Disease. J Am Coll Cardiol. 2019 09 24; 74(12):1543-1553. PMID: 31537263; PMCID: PMC6756178; DOI: 10.1016/j.jacc.2019.06.077;

Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 08 21; 366:l4570.View Related Profiles.

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Beiser, Alexa
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PMID: 31393881; PMCID: PMC6687152; DOI: 10.1371/journal.pone.0219261;

Huan T, Mendelson M, Joehanes R, Yao C, Liu C, Song C, Bhattacharya A, Rong J, Tanriverdi K, Keefe J, Murabito JM, Courchesne P, Larson MG, Freedman JE, Levy D. Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits. Epigenetics. 2020 Jan - Feb; 15(1-2):183-198.View Related Profiles.

Liu, Chunyu
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Behnam V, Rong J, Larson MG, Gotal JD, Benjamin EJ, Hamburg NM, Vasan RS, Mitchell GF. Windkessel Measures Derived From Pressure Waveforms Only: The Framingham Heart Study. J Am Heart Assoc. 2019 07 16; 8(14):e012300.View Related Profiles.

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Henglin M, Niiranen T, Watrous JD, Lagerborg KA, Antonelli J, Claggett BL, Demosthenes EJ, von Jeinsen B, Demler O, Vasan RS, Larson MG, Jain M, Cheng S. A Single Visualization Technique for Displaying Multiple Metabolite-Phenotype Associations. Metabolites. 2019 Jul 02; 9(7). PMID: 31269707; PMCID: PMC6680673; DOI: 10.3390/metabo9070128;

Kaess BM, Andersson C, Duncan MS, Larson MG, Aasbjerg K, Gislason GH, Torp-Pedersen C, Vasan RS. Familial Clustering of Cardiac Conduction Defects and Pacemaker Insertion. Circ Arrhythm Electrophysiol. 2019 07; 12(7):e007150.View Related Profiles.

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Ko D, Benson MD, Ngo D, Yang Q, Larson MG, Wang TJ, Trinquart L, McManus DD, Lubitz SA, Ellinor PT, Vasan RS, Gerszten RE, Benjamin EJ, Lin H. Proteomics Profiling and Risk of New-Onset Atrial Fibrillation: Framingham Heart Study. J Am Heart Assoc. 2019 03 19; 8(6):e010976.View Related Profiles.

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Echouffo-Tcheugui JB, Short MI, Xanthakis V, Field P, Sponholtz TR, Larson MG, Vasan RS. Natural History of Obesity Subphenotypes: Dynamic Changes Over Two Decades and Prognosis in the Framingham Heart Study. J Clin Endocrinol Metab. 2019 03 01; 104(3):738-752.View Related Profiles.

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Spartano NL, Lyass A, Larson MG, Tran T, Andersson C, Blease SJ, Esliger DW, Vasan RS, Murabito JM. Objective physical activity and physical performance in middle-aged and older adults. Exp Gerontol. 2019 05; 119:203-211.View Related Profiles.

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Dörr M, Hamburg NM, Müller C, Smith NL, Gustafsson S, Lehtimäki T, Teumer A, Zeller T, Li X, Lind L, Raitakari OT, Völker U, Blankenberg S, McKnight B, Morris AP, Kähönen M, Lemaitre RN, Wild PS, Nauck M, Völzke H, Münzel T, Mitchell GF, Psaty BM, Lindgren CM, Larson MG, Felix SB, Ingelsson E, Lyytikäinen LP, Herrington D, Benjamin EJ, Schnabel RB. Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. Circ Genom Precis Med. 2019 02; 12(2):e002409.View Related Profiles.

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Watrous JD, Niiranen TJ, Lagerborg KA, Henglin M, Xu YJ, Rong J, Sharma S, Vasan RS, Larson MG, Armando A, Mora S, Quehenberger O, Dennis EA, Cheng S, Jain M. Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins. Cell Chem Biol. 2019 03 21; 26(3):433-442.e4. PMID: 30661990; PMCID: PMC6636917; DOI: 10.1016/j.chembiol.2018.11.015;

Lin H, Lunetta KL, Zhao Q, Mandaviya PR, Rong J, Benjamin EJ, Joehanes R, Levy D, van Meurs JBJ, Larson MG, Murabito JM. Whole Blood Gene Expression Associated With Clinical Biological Age. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):81-88.View Related Profiles.

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Ghorbani A, Bhambhani V, Christenson RH, Meijers WC, de Boer RA, Levy D, Larson MG, Ho JE. Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes. J Am Coll Cardiol. 2018 12 25; 72(25):3246-3254. PMID: 30573026; PMCID: PMC6516745; DOI: 10.1016/j.jacc.2018.09.076;

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Shah RV, Rong J, Larson MG, Yeri A, Ziegler O, Tanriverdi K, Murthy V, Liu X, Xiao C, Pico AR, Huan T, Levy D, Lewis GD, Rosenzweig A, Vasan RS, Das S, Freedman JE. Associations of Circulating Extracellular RNAs With Myocardial Remodeling and Heart Failure. JAMA Cardiol. 2018 09 01; 3(9):871-876. PMID: 30090932; PMCID: PMC6233646; DOI: 10.1001/jamacardio.2018.2371;

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Ho JE, Lyass A, Courchesne P, Chen G, Liu C, Yin X, Hwang SJ, Massaro JM, Larson MG, Levy D. Protein Biomarkers of Cardiovascular Disease and Mortality in the Community. J Am Heart Assoc. 2018 07 13; 7(14).View Related Profiles.

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Tsao CW, Lyass A, Enserro D, Larson MG, Ho JE, Kizer JR, Gottdiener JS, Psaty BM, Vasan RS. Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction. JACC Heart Fail. 2018 08; 6(8):678-685. PMID: 30007560; PMCID: PMC6076350; DOI: 10.1016/j.jchf.2018.03.006;

Savji N, Meijers WC, Bartz TM, Bhambhani V, Cushman M, Nayor M, Kizer JR, Sarma A, Blaha MJ, Gansevoort RT, Gardin JM, Hillege HL, Ji F, Kop WJ, Lau ES, Lee DS, Sadreyev R, van Gilst WH, Wang TJ, Zanni MV, Vasan RS, Allen NB, Psaty BM, van der Harst P, Levy D, Larson M, Shah SJ, de Boer RA, Gottdiener JS, Ho JE. The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF. JACC Heart Fail. 2018 08; 6(8):701-709.View Related Profiles.

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Benjamin, Emelia
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Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 05 09; 73(6):757-762.View Related Profiles.

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PMID: 28977464; PMCID: PMC5946832; DOI: 10.1093/gerona/glx144;

Echouffo-Tcheugui JB, Niiranen TJ, McCabe EL, Jain M, Vasan RS, Larson MG, Cheng S. Lifetime Prevalence and Prognosis of Prediabetes Without Progression to Diabetes. Diabetes Care. 2018 07; 41(7):e117-e118. PMID: 29724784; PMCID: PMC6014534; DOI: 10.2337/dc18-0524;

Niiranen TJ, Henglin M, Claggett B, Muggeo VMR, McCabe E, Jain M, Vasan RS, Larson MG, Cheng S. Trajectories of Blood Pressure Elevation Preceding Hypertension Onset: An Analysis of the Framingham Heart Study Original Cohort. JAMA Cardiol. 2018 05 01; 3(5):427-431. PMID: 29562081; PMCID: PMC5875333; DOI: 10.1001/jamacardio.2018.0250;

Niiranen TJ, Lin H, Larson MG, Vasan RS. Familial clustering of hypertensive target organ damage in the community. J Hypertens. 2018 05; 36(5):1086-1093.View Related Profiles.

Lin, Honghuang
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PMID: 29369144; DOI: 10.1097/HJH.0000000000001679;

Staerk L, Wang B, Preis SR, Larson MG, Lubitz SA, Ellinor PT, McManus DD, Ko D, Weng LC, Lunetta KL, Frost L, Benjamin EJ, Trinquart L. Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study. BMJ. 2018 04 26; 361:k1453.View Related Profiles.

Wang, Biqi
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PMID: 29699974; PMCID: PMC5917175; DOI: 10.1136/bmj.k1453;

Andersson C, Lyass A, Lin H, Køber L, Larson MG, Vasan RS. Association of Genetic Variation in Coronary Artery Disease-Related Loci With the Risk of Heart Failure With Preserved Versus Reduced Ejection Fraction. Circulation. 2018 03 20; 137(12):1290-1292.View Related Profiles.

Lin, Honghuang
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PMID: 29555712; PMCID: PMC5870132; DOI: 10.1161/CIRCULATIONAHA.117.032491;

Nayor M, Enserro DM, Xanthakis V, Larson MG, Benjamin EJ, Aragam J, Mitchell GF, Vasan RS. Comorbidities and Cardiometabolic Disease: Relationship With Longitudinal Changes in Diastolic Function. JACC Heart Fail. 2018 04; 6(4):317-325.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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PMID: 29525334; PMCID: PMC5878123; DOI: 10.1016/j.jchf.2017.12.018;

Tynkkynen J, Chouraki V, van der Lee SJ, Hernesniemi J, Yang Q, Li S, Beiser A, Larson MG, Sääksjärvi K, Shipley MJ, Singh-Manoux A, Gerszten RE, Wang TJ, Havulinna AS, Würtz P, Fischer K, Demirkan A, Ikram MA, Amin N, Lehtimäki T, Kähönen M, Perola M, Metspalu A, Kangas AJ, Soininen P, Ala-Korpela M, Vasan RS, Kivimäki M, van Duijn CM, Seshadri S, Salomaa V. Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts. Alzheimers Dement. 2018 06; 14(6):723-733.View Related Profiles.

Beiser, Alexa
Larson, Martin
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PMID: 29519576; PMCID: PMC6082422; DOI: 10.1016/j.jalz.2018.01.003;

Puurunen MK, Hwang SJ, Larson MG, Vasan RS, O'Donnell CJ, Tofler G, Johnson AD. ADP Platelet Hyperreactivity Predicts Cardiovascular Disease in the FHS (Framingham Heart Study). J Am Heart Assoc. 2018 03 03; 7(5).View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 29502103; PMCID: PMC5866343; DOI: 10.1161/JAHA.118.008522;

de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Shah SJ, Levy D, Herrington DM, Larson MG, van Gilst WH, Gottdiener JS, Bertoni AG, Ho JE. Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. JAMA Cardiol. 2018 03 01; 3(3):215-224.View Related Profiles.

Benjamin, Emelia
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PMID: 29322198; PMCID: PMC5862778; DOI: 10.1001/jamacardio.2017.4987;

Liu C, Fetterman JL, Liu P, Luo Y, Larson MG, Vasan RS, Zhu J, Levy D. Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes. Hum Genet. 2018 Mar; 137(3):203-213.View Related Profiles.

Liu, Chunyu
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PMID: 29423652; PMCID: PMC6335583; DOI: 10.1007/s00439-018-1873-4;

Nayor M, Duncan MS, Musani SK, Xanthakis V, LaValley MP, Larson MG, Fox ER, Vasan RS. Incidence of cardiovascular disease in individuals affected by recent changes to US blood pressure treatment guidelines. J Hypertens. 2018 02; 36(2):436-443.View Related Profiles.

Larson, Martin
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PMID: 29084083; PMCID: PMC6062206; DOI: 10.1097/HJH.0000000000001570;

Lieb W, Enserro DM, Larson MG, Vasan RS. Residual cardiovascular risk in individuals on lipid-lowering treatment: quantifying absolute and relative risk in the community. Open Heart. 2018; 5(1):e000722. PMID: 29387429; PMCID: PMC5786911; DOI: 10.1136/openhrt-2017-000722;

Zachariah JP, Rong J, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Mitchell GF. Metabolic Predictors of Change in Vascular Function: Prospective Associations From a Community-Based Cohort. Hypertension. 2018 02; 71(2):237-242.View Related Profiles.

Benjamin, Emelia
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PMID: 29279312; PMCID: PMC5764805; DOI: 10.1161/HYPERTENSIONAHA.117.10054;

Benson MD, Yang Q, Ngo D, Zhu Y, Shen D, Farrell LA, Sinha S, Keyes MJ, Vasan RS, Larson MG, Smith JG, Wang TJ, Gerszten RE. Genetic Architecture of the Cardiovascular Risk Proteome. Circulation. 2018 03 13; 137(11):1158-1172.View Related Profiles.

Larson, Martin
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PMID: 29258991; PMCID: PMC5849518; DOI: 10.1161/CIRCULATIONAHA.117.029536;

Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Levy D, Herrington DM, van Gilst WH, Bertoni AG, Larson MG, de Boer RA, Gottdiener JS, Shah SJ, Ho JE. Predictors and outcomes of heart failure with mid-range ejection fraction. Eur J Heart Fail. 2018 04; 20(4):651-659.View Related Profiles.

Benjamin, Emelia
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PMID: 29226491; PMCID: PMC5899688; DOI: 10.1002/ejhf.1091;

Weng LC, Preis SR, Hulme OL, Larson MG, Choi SH, Wang B, Trinquart L, McManus DD, Staerk L, Lin H, Lunetta KL, Ellinor PT, Benjamin EJ, Lubitz SA. Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. Circulation. 2018 03 06; 137(10):1027-1038.View Related Profiles.

Wang, Biqi
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PMID: 29129827; PMCID: PMC5840011; DOI: 10.1161/CIRCULATIONAHA.117.031431;

Lin H, Lunetta KL, Zhao Q, Rong J, Benjamin EJ, Mendelson MM, Joehanes R, Levy D, Larson MG, Murabito JM. Transcriptome-wide association study of inflammatory biologic age. Aging (Albany NY). 2017 Nov 11; 9(11):2288-2301.View Related Profiles.

Benjamin, Emelia
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PMID: 29135455; PMCID: PMC5723687; DOI: 10.18632/aging.101321;

Qazi S, Gona PN, Salton CJ, Bajaj NS, Larson MG, O'Donnell CJ, Manning WJ, Chuang ML. Impact of Left Ventricular Trabeculations and Papillary Muscles on Mass, Geometry, and Association With Incident Adverse Cardiovascular Events: The Framingham Heart Study. JACC Cardiovasc Imaging. 2018 Apr; 11(4):653-654.View Related Profiles.

O'Donnell, Christopher
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Huan T, Chen G, Liu C, Bhattacharya A, Rong J, Chen BH, Seshadri S, Tanriverdi K, Freedman JE, Larson MG, Murabito JM, Levy D. Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits. Aging Cell. 2018 02; 17(1).View Related Profiles.

Liu, Chunyu
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PMID: 29044988; PMCID: PMC5770777; DOI: 10.1111/acel.12687;

Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2018 01; 11(1):1-11.View Related Profiles.

Benjamin, Emelia
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PMID: 28917679; PMCID: PMC5756128; DOI: 10.1016/j.jcmg.2017.08.007;

Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, Larson MG, Levy D. MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage. Circ Cardiovasc Genet. 2017 Oct; 10(5).View Related Profiles.

Benjamin, Emelia
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PMID: 29030400; PMCID: PMC5683429; DOI: 10.1161/CIRCGENETICS.116.001678;

Niiranen TJ, Larson MG, McCabe EL, Xanthakis V, Vasan RS, Cheng S. Prognosis of Prehypertension Without Progression to Hypertension. Circulation. 2017 09 26; 136(13):1262-1264.View Related Profiles.

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PMID: 28947482; PMCID: PMC5658013; DOI: 10.1161/CIRCULATIONAHA.117.029317;

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J. 2017 Aug 01; 38(29):2300-2308.View Related Profiles.

Larson, Martin
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PMID: 28430902; PMCID: PMC6075041; DOI: 10.1093/eurheartj/ehx134;

Murabito JM, Rong J, Lunetta KL, Huan T, Lin H, Zhao Q, Freedman JE, Tanriverdi K, Levy D, Larson MG. Cross-sectional relations of whole-blood miRNA expression levels and hand grip strength in a community sample. Aging Cell. 2017 Aug; 16(4):888-894.View Related Profiles.

Lin, Honghuang
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PMID: 28597569; PMCID: PMC5506437; DOI: 10.1111/acel.12622;

Chouraki V, Preis SR, Yang Q, Beiser A, Li S, Larson MG, Weinstein G, Wang TJ, Gerszten RE, Vasan RS, Seshadri S. Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study. Alzheimers Dement. 2017 Dec; 13(12):1327-1336.View Related Profiles.

Beiser, Alexa
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PMID: 28602601; PMCID: PMC5722716; DOI: 10.1016/j.jalz.2017.04.009;

Niiranen TJ, Lyass A, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study. Hypertension. 2017 Aug; 70(2):267-274.View Related Profiles.

Benjamin, Emelia
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PMID: 28559398; PMCID: PMC5509504; DOI: 10.1161/HYPERTENSIONAHA.117.09026;

Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ. 2017 May 12; 357:j1949.View Related Profiles.

Larson, Martin
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PMID: 28500036; PMCID: PMC5430541; DOI: 10.1136/bmj.j1949;

Kimberly WT, O'Sullivan JF, Nath AK, Keyes M, Shi X, Larson MG, Yang Q, Long MT, Vasan R, Peterson RT, Wang TJ, Corey KE, Gerszten RE. Metabolite profiling identifies anandamide as a biomarker of nonalcoholic steatohepatitis. JCI Insight. 2017 May 04; 2(9).View Related Profiles.

Larson, Martin
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Long MT, Yin X, Larson MG, Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Staerk L, Ko D, Helm RH, Hoffmann U, Chung RT, Benjamin EJ. Relations of Liver Fat With Prevalent and Incident Atrial Fibrillation in the Framingham Heart Study. J Am Heart Assoc. 2017 May 02; 6(5).View Related Profiles.

Ko, Darae
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PMID: 28465298; PMCID: PMC5524082; DOI: 10.1161/JAHA.116.005227;

Ho JE, McCabe EL, Wang TJ, Larson MG, Levy D, Tsao C, Aragam J, Mitchell GF, Benjamin EJ, Vasan RS, Cheng S. Cardiometabolic Traits and Systolic Mechanics in the Community. Circ Heart Fail. 2017 May; 10(5).View Related Profiles.

Levy, Daniel
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PMID: 28495953; PMCID: PMC5500189; DOI: 10.1161/CIRCHEARTFAILURE.116.003536;

Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundström J, Minelli C, Ruggiero D, Lyytikäinen LP, Tiller D, Smith JG, Monnereau C, Di Tullio MR, Musani SK, Morrison AC, Pers TH, Morley M, Kleber ME, Aragam J, Benjamin EJ, Bis JC, Bisping E, Broeckel U, Cheng S, Deckers JW, Del Greco M F, Edelmann F, Fornage M, Franke L, Friedrich N, Harris TB, Hofer E, Hofman A, Huang J, Hughes AD, Kähönen M, Investigators K, Kruppa J, Lackner KJ, Lannfelt L, Laskowski R, Launer LJ, Leosdottir M, Lin H, Lindgren CM, Loley C, MacRae CA, Mascalzoni D, Mayet J, Medenwald D, Morris AP, Müller C, Müller-Nurasyid M, Nappo S, Nilsson PM, Nuding S, Nutile T, Peters A, Pfeufer A, Pietzner D, Pramstaller PP, Raitakari OT, Rice KM, Rivadeneira F, Rotter JI, Ruohonen ST, Sacco RL, Samdarshi TE, Schmidt H, Sharp ASP, Shields DC, Sorice R, Sotoodehnia N, Stricker BH, Surendran P, Thom S, Töglhofer AM, Uitterlinden AG, Wachter R, Völzke H, Ziegler A, Münzel T, März W, Cappola TP, Hirschhorn JN, Mitchell GF, Smith NL, Fox ER, Dueker ND, Jaddoe VWV, Melander O, Russ M, Lehtimäki T, Ciullo M, Hicks AA, Lind L, Gudnason V, Pieske B, Barron AJ, Zweiker R, Schunkert H, Ingelsson E, Liu K, Arnett DK, Psaty BM, Blankenberg S, Larson MG, Felix SB, Franco OH, Zeller T, Vasan RS, Dörr M. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest. 2017 May 01; 127(5):1798-1812.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
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PMID: 28394258; PMCID: PMC5409098; DOI: 10.1172/JCI84840;

Niiranen TJ, Kalesan B, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Aortic-Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community: The Framingham Heart Study. Hypertension. 2017 Jun; 69(6):1022-1028.View Related Profiles.

Kalesan, Bindu
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PMID: 28396534; PMCID: PMC5426958; DOI: 10.1161/HYPERTENSIONAHA.116.08917;

Torjesen A, Cooper LL, Rong J, Larson MG, Hamburg NM, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study. Hypertension. 2017 Apr; 69(4):685-690.View Related Profiles.

Levy, Daniel
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PMID: 28264924; PMCID: PMC5382873; DOI: 10.1161/HYPERTENSIONAHA.116.08116;

McMahon GM, Hwang SJ, Clish CB, Tin A, Yang Q, Larson MG, Rhee EP, Li M, Levy D, O'Donnell CJ, Coresh J, Young JH, Gerszten RE, Fox CS. Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease. Kidney Int. 2017 Jun; 91(6):1426-1435.View Related Profiles.

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PMID: 28302371; DOI: 10.1016/j.kint.2017.01.007;

Mick E, Shah R, Tanriverdi K, Murthy V, Gerstein M, Rozowsky J, Kitchen R, Larson MG, Levy D, Freedman JE. Stroke and Circulating Extracellular RNAs. Stroke. 2017 Apr; 48(4):828-834.View Related Profiles.

Levy, Daniel
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PMID: 28289238; PMCID: PMC5373984; DOI: 10.1161/STROKEAHA.116.015140;

Nayor M, Larson MG, Wang N, Santhanakrishnan R, Lee DS, Tsao CW, Cheng S, Benjamin EJ, Vasan RS, Levy D, Fox CS, Ho JE. The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction. Eur J Heart Fail. 2017 May; 19(5):615-623.View Related Profiles.

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PMID: 28217978; PMCID: PMC5423843; DOI: 10.1002/ejhf.778;

Shah R, Murthy V, Pacold M, Danielson K, Tanriverdi K, Larson MG, Hanspers K, Pico A, Mick E, Reis J, de Ferranti S, Freinkman E, Levy D, Hoffmann U, Osganian S, Das S, Freedman JE. Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes. Diabetes Care. 2017 Apr; 40(4):546-553. PMID: 28183786; PMCID: PMC5360281; DOI: 10.2337/dc16-1354;

McManus DD, Rong J, Huan T, Lacey S, Tanriverdi K, Munson PJ, Larson MG, Joehanes R, Murthy V, Shah R, Freedman JE, Levy D. Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors. BMC Genomics. 2017 Feb 08; 18(1):139. PMID: 28178938; PMCID: PMC5299677; DOI: 10.1186/s12864-017-3533-9;

Watrous JD, Henglin M, Claggett B, Lehmann KA, Larson MG, Cheng S, Jain M. Visualization, Quantification, and Alignment of Spectral Drift in Population Scale Untargeted Metabolomics Data. Anal Chem. 2017 02 07; 89(3):1399-1404. PMID: 28208263; PMCID: PMC5455767; DOI: 10.1021/acs.analchem.6b04337;

Spartano NL, Stevenson MD, Xanthakis V, Larson MG, Andersson C, Murabito JM, Vasan RS. Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes. 2017 Apr; 7(2):59-69.View Related Profiles.

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PMID: 28112860; PMCID: PMC5339058; DOI: 10.1111/cob.12177;

Bell V, McCabe EL, Larson MG, Rong J, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Benjamin EJ, Hamburg NM, Vasan RS, Mitchell GF, Cheng S. Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community. J Am Heart Assoc. 2017 Jan 09; 6(1).View Related Profiles.

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PMID: 28069573; PMCID: PMC5523643; DOI: 10.1161/JAHA.116.004903;

Lin H, Yin X, Xie Z, Lunetta KL, Lubitz SA, Larson MG, Ko D, Magnani JW, Mendelson MM, Liu C, McManus DD, Levy D, Ellinor PT, Benjamin EJ. Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study. Sci Rep. 2017 01 09; 7:40377.View Related Profiles.

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PMID: 28067321; PMCID: PMC5220313; DOI: 10.1038/srep40377;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Reply. J Hypertens. 2016 12; 34(12):2489-2490.View Related Profiles.

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PMID: 27805916

Cooper LL, Palmisano JN, Benjamin EJ, Larson MG, Vasan RS, Mitchell GF, Hamburg NM. Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study. Circ Cardiovasc Imaging. 2016 Dec; 9(12).View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27956408; PMCID: PMC5557409; DOI: 10.1161/CIRCIMAGING.116.004979;

Lubitz SA, Yin X, Lin HJ, Kolek M, Smith JG, Trompet S, Rienstra M, Rost NS, Teixeira PL, Almgren P, Anderson CD, Chen LY, Engström G, Ford I, Furie KL, Guo X, Larson MG, Lunetta KL, Macfarlane PW, Psaty BM, Soliman EZ, Sotoodehnia N, Stott DJ, Taylor KD, Weng LC, Yao J, Geelhoed B, Verweij N, Siland JE, Kathiresan S, Roselli C, Roden DM, van der Harst P, Darbar D, Jukema JW, Melander O, Rosand J, Rotter JI, Heckbert SR, Ellinor PT, Alonso A, Benjamin EJ. Genetic Risk Prediction of Atrial Fibrillation. Circulation. 2017 Apr 04; 135(14):1311-1320.View Related Profiles.

Benjamin, Emelia
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PMID: 27793994; PMCID: PMC5380586; DOI: 10.1161/CIRCULATIONAHA.116.024143;

Bretón-Romero R, Wang N, Palmisano J, Larson MG, Vasan RS, Mitchell GF, Benjamin EJ, Vita JA, Hamburg NM. Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2452-2459.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27789476; PMCID: PMC5557404; DOI: 10.1161/ATVBAHA.116.307948;

McManus DD, Yin X, Gladstone R, Vittinghoff E, Vasan RS, Larson MG, Benjamin EJ, Marcus GM. Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation. J Am Heart Assoc. 2016 Sep 14; 5(9).View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27628571; PMCID: PMC5079048; DOI: 10.1161/JAHA.116.004060;

Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S, Guo X, Palmas W, Martin LW, Chen YD, Surendran P, Drenos F, Cook JP, Auer PL, Chu AY, Giri A, Zhao W, Jakobsdottir J, Lin LA, Stafford JM, Amin N, Mei H, Yao J, Voorman A, Larson MG, Grove ML, Smith AV, Hwang SJ, Chen H, Huan T, Kosova G, Stitziel NO, Kathiresan S, Samani N, Schunkert H, Deloukas P, Li M, Fuchsberger C, Pattaro C, Gorski M, Kooperberg C, Papanicolaou GJ, Rossouw JE, Faul JD, Kardia SL, Bouchard C, Raffel LJ, Uitterlinden AG, Franco OH, Vasan RS, O'Donnell CJ, Taylor KD, Liu K, Bottinger EP, Gottesman O, Daw EW, Giulianini F, Ganesh S, Salfati E, Harris TB, Launer LJ, Dörr M, Felix SB, Rettig R, Völzke H, Kim E, Lee WJ, Lee IT, Sheu WH, Tsosie KS, Edwards DR, Liu Y, Correa A, Weir DR, Völker U, Ridker PM, Boerwinkle E, Gudnason V, Reiner AP, van Duijn CM, Borecki IB, Edwards TL, Chakravarti A, Rotter JI, Psaty BM, Loos RJ, Fornage M, Ehret GB, Newton-Cheh C, Levy D, Chasman DI. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nat Genet. 2016 Oct; 48(10):1162-70.View Related Profiles.

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PMID: 27618448; PMCID: PMC5320952; DOI: 10.1038/ng.3660;

Meneton P, Lemogne C, Herquelot E, Bonenfant S, Larson MG, Vasan RS, Ménard J, Goldberg M, Zins M. A Global View of the Relationships between the Main Behavioural and Clinical Cardiovascular Risk Factors in the GAZEL Prospective Cohort. PLoS One. 2016; 11(9):e0162386.View Related Profiles.

Larson, Martin
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PMID: 27598908; PMCID: PMC5012694; DOI: 10.1371/journal.pone.0162386;

Mitchell GF, Hwang SJ, Larson MG, Hamburg NM, Benjamin EJ, Vasan RS, Levy D, Vita JA. Transfer function-derived central pressure and cardiovascular disease events: the Framingham Heart Study. J Hypertens. 2016 Aug; 34(8):1528-34.View Related Profiles.

Levy, Daniel
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PMID: 27219486; PMCID: PMC6206853; DOI: 10.1097/HJH.0000000000000968;

Ngo D, Sinha S, Shen D, Kuhn EW, Keyes MJ, Shi X, Benson MD, O'Sullivan JF, Keshishian H, Farrell LA, Fifer MA, Vasan RS, Sabatine MS, Larson MG, Carr SA, Wang TJ, Gerszten RE. Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease. Circulation. 2016 Jul 26; 134(4):270-85.View Related Profiles.

Larson, Martin
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PMID: 27444932; PMCID: PMC4963294; DOI: 10.1161/CIRCULATIONAHA.116.021803;

Rhee EP, Yang Q, Yu B, Liu X, Cheng S, Deik A, Pierce KA, Bullock K, Ho JE, Levy D, Florez JC, Kathiresan S, Larson MG, Vasan RS, Clish CB, Wang TJ, Boerwinkle E, O'Donnell CJ, Gerszten RE. An exome array study of the plasma metabolome. Nat Commun. 2016 07 25; 7:12360.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 27453504; PMCID: PMC4962516; DOI: 10.1038/ncomms12360;

Andersson C, Quiroz R, Enserro D, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Mitchell GF, Vasan RS. Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):584-9.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Larson, Martin
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PMID: 27456526; PMCID: PMC5002314; DOI: 10.1161/HYPERTENSIONAHA.116.07426;

Shaikh AY, Wang N, Yin X, Larson MG, Vasan RS, Hamburg NM, Magnani JW, Ellinor PT, Lubitz SA, Mitchell GF, Benjamin EJ, McManus DD. Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study. Hypertension. 2016 Sep; 68(3):590-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27456517; DOI: 10.1161/HYPERTENSIONAHA.116.07650;

Puurunen MK, Enserro D, Xanthakis V, Larson MG, Benjamin EJ, Tofler GH, Wollert KC, O'Donnell CJ, Vasan RS. Biomarkers for the prediction of venous thromboembolism in the community. Thromb Res. 2016 Sep; 145:34-9.View Related Profiles.

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PMID: 27447083; DOI: 10.1016/j.thromres.2016.07.006;

Rahman F, Yin X, Larson MG, Ellinor PT, Lubitz SA, Vasan RS, McManus DD, Magnani JW, Benjamin EJ. Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study. Hypertension. 2016 Sep; 68(3):597-605.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 27512109; PMCID: PMC4982514; DOI: 10.1161/HYPERTENSIONAHA.116.07683;

Xanthakis V, Enserro DM, Larson MG, Wollert KC, Januzzi JL, Levy D, Aragam J, Benjamin EJ, Cheng S, Wang TJ, Mitchell GF, Vasan RS. Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community. JACC Heart Fail. 2016 Oct; 4(10):808-815.View Related Profiles.

Levy, Daniel
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PMID: 27395350; DOI: 10.1016/j.jchf.2016.05.001;

Puurunen MK, Gona PN, Larson MG, Murabito JM, Magnani JW, O'Donnell CJ. Epidemiology of venous thromboembolism in the Framingham Heart Study. Thromb Res. 2016 Sep; 145:27-33.View Related Profiles.

O'Donnell, Christopher
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PMID: 27442716; PMCID: PMC5385100; DOI: 10.1016/j.thromres.2016.06.033;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction". Circulation. 2016 Jun 7; 133(23):e692-3.View Related Profiles.

Levy, Daniel
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Larson, Martin
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PMID: 27267541; PMCID: PMC4902166; DOI: 10.1161/CIRCULATIONAHA.116.022835;

Ho JE, Enserro D, Brouwers FP, Kizer JR, Shah SJ, Psaty BM, Bartz TM, Santhanakrishnan R, Lee DS, Chan C, Liu K, Blaha MJ, Hillege HL, van der Harst P, van Gilst WH, Kop WJ, Gansevoort RT, Vasan RS, Gardin JM, Levy D, Gottdiener JS, de Boer RA, Larson MG. Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes. Circ Heart Fail. 2016 Jun; 9(6).View Related Profiles.

Levy, Daniel
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PMID: 27266854; PMCID: PMC4902276; DOI: 10.1161/CIRCHEARTFAILURE.115.003116;

Tsao CW, Lyass A, Larson MG, Cheng S, Lam CS, Aragam JR, Benjamin EJ, Vasan RS. Prognosis of Adults With Borderline Left Ventricular Ejection Fraction. JACC Heart Fail. 2016 Jun; 4(6):502-10.View Related Profiles.

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PMID: 27256754; PMCID: PMC4932891; DOI: 10.1016/j.jchf.2016.03.003;

Spartano NL, Lyass A, Larson MG, Lewis GD, Vasan RS. Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study. J Am Heart Assoc. 2016 May 27; 5(6).View Related Profiles.

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PMID: 27233297; PMCID: PMC4937245; DOI: 10.1161/JAHA.115.002821;

Christophersen IE, Yin X, Larson MG, Lubitz SA, Magnani JW, McManus DD, Ellinor PT, Benjamin EJ. A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study. Am Heart J. 2016 Aug; 178:45-54.View Related Profiles.

Benjamin, Emelia
Larson, Martin

PMID: 27502851; PMCID: PMC5344697; DOI: 10.1016/j.ahj.2016.05.004;

Kim EJ, Yin X, Fontes JD, Magnani JW, Lubitz SA, McManus DD, Seshadri S, Vasan RS, Ellinor PT, Larson MG, Benjamin EJ, Rienstra M. Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study). Am Heart J. 2016 Jul; 177:138-44.View Related Profiles.

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PMID: 27297859; PMCID: PMC4908973; DOI: 10.1016/j.ahj.2016.03.023;

Shah R, Tanriverdi K, Levy D, Larson M, Gerstein M, Mick E, Rozowsky J, Kitchen R, Murthy V, Mikalev E, Freedman JE. Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources. PLoS One. 2016; 11(4):e0153691. PMID: 27123852; PMCID: PMC4849639; DOI: 10.1371/journal.pone.0153691;

McCabe EL, Larson MG, Lunetta KL, Newman AB, Cheng S, Murabito JM. Association of an Index of Healthy Aging With Incident Cardiovascular Disease and Mortality in a Community-Based Sample of Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Dec; 71(12):1695-1701.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
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PMID: 27117172; PMCID: PMC5106860; DOI: 10.1093/gerona/glw077;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Cheng S, Aragam J, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 25; 5(3):e002693.View Related Profiles.

Kaess, Bernhard
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PMID: 27016574; PMCID: PMC4943246; DOI: 10.1161/JAHA.115.002693;

Santhanakrishnan R, Wang N, Larson MG, Magnani JM, Vasan RS, Wang TJ, Yap J, Feng L, Yap KB, Ong HY, Ng TP, Richards AM, Lam CS, Ho JE. Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians. J Am Heart Assoc. 2016 Mar 25; 5(3):e002956.View Related Profiles.

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PMID: 27016575; PMCID: PMC4943269; DOI: 10.1161/JAHA.115.002956;

Delling FN, Rong J, Larson MG, Lehman B, Fuller D, Osypiuk E, Stantchev P, Hackman B, Manning WJ, Benjamin EJ, Levine RA, Vasan RS. Evolution of Mitral Valve Prolapse: Insights From the Framingham Heart Study. Circulation. 2016 Apr 26; 133(17):1688-95.View Related Profiles.

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PMID: 27006478; PMCID: PMC4856536; DOI: 10.1161/CIRCULATIONAHA.115.020621;

Schnabel RB, Maas R, Wang N, Yin X, Larson MG, Levy D, Ellinor PT, Lubitz SA, McManus DD, Magnani JW, Atzler D, Böger RH, Schwedhelm E, Vasan RS, Benjamin EJ. Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation. Am Heart J. 2016 Jun; 176:100-6.View Related Profiles.

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PMID: 27264226; PMCID: PMC4899814; DOI: 10.1016/j.ahj.2016.03.007;

Yin X, Subramanian S, Willinger CM, Chen G, Juhasz P, Courchesne P, Chen BH, Li X, Hwang SJ, Fox CS, O'Donnell CJ, Muntendam P, Fuster V, Bobeldijk-Pastorova I, Sookoian SC, Pirola CJ, Gordon N, Adourian A, Larson MG, Levy D. Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes. J Clin Endocrinol Metab. 2016 Apr; 101(4):1779-89.View Related Profiles.

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Levy, Daniel
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PMID: 26908103; PMCID: PMC4880163; DOI: 10.1210/jc.2015-2555;

Andersson C, Enserro D, Sullivan L, Wang TJ, Januzzi JL, Benjamin EJ, Vita JA, Hamburg NM, Larson MG, Mitchell GF, Vasan RS. Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis. 2016 May; 248:245-51.View Related Profiles.

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PMID: 26972631; PMCID: PMC5018232; DOI: 10.1016/j.atherosclerosis.2016.02.013;

Ho JE, Larson MG, Ghorbani A, Cheng S, Chen MH, Keyes M, Rhee EP, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes. PLoS One. 2016; 11(2):e0148361.View Related Profiles.

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PMID: 26863521; PMCID: PMC4749349; DOI: 10.1371/journal.pone.0148361;

Tsao CW, Himali JJ, Beiser AS, Larson MG, DeCarli C, Vasan RS, Mitchell GF, Seshadri S. Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology. 2016 Feb 16; 86(7):619-26.View Related Profiles.

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PMID: 26791155; PMCID: PMC4762417; DOI: 10.1212/WNL.0000000000002368;

Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S. Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension. 2016 Mar; 67(3):513-9.View Related Profiles.

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PMID: 26754644; PMCID: PMC4752398; DOI: 10.1161/HYPERTENSIONAHA.115.06610;

Santhanakrishnan R, Wang N, Larson MG, Magnani JW, McManus DD, Lubitz SA, Ellinor PT, Cheng S, Vasan RS, Lee DS, Wang TJ, Levy D, Benjamin EJ, Ho JE. Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction. Circulation. 2016 Feb 2; 133(5):484-92.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
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Ramachandran, Vasan

PMID: 26746177; PMCID: PMC4738087; DOI: 10.1161/CIRCULATIONAHA.115.018614;

Nayor M, Wang N, Larson MG, Vasan RS, Levy D, Ho JE. Circulating Galectin-3 Is Associated With Cardiometabolic Disease in the Community. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles.

Larson, Martin
Nayor, Matthew
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PMID: 26722123; PMCID: PMC4859357; DOI: 10.1161/JAHA.115.002347;

Liu CK, Lyass A, Larson MG, Massaro JM, Wang N, D'Agostino RB, Benjamin EJ, Murabito JM. Biomarkers of oxidative stress are associated with frailty: the Framingham Offspring Study. Age (Dordr). 2016 Feb; 38(1):1.View Related Profiles.

Liu, Christine
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PMID: 26695510; PMCID: PMC5005887; DOI: 10.1007/s11357-015-9864-z;

Zachariah JP, Hwang S, Hamburg NM, Benjamin EJ, Larson MG, Levy D, Vita JA, Sullivan LM, Mitchell GF, Vasan RS. Circulating Adipokines and Vascular Function: Cross-Sectional Associations in a Community-Based Cohort. Hypertension. 2016 Feb; 67(2):294-300.View Related Profiles.

Levy, Daniel
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PMID: 26628673; PMCID: PMC4845672; DOI: 10.1161/HYPERTENSIONAHA.115.05949;

Chami HA, Vasan RS, Larson MG, Benjamin EJ, Mitchell GF, Gottlieb DJ. The association between sleep-disordered breathing and aortic stiffness in a community cohort. Sleep Med. 2016 Mar; 19:69-74.View Related Profiles.

Benjamin, Emelia
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PMID: 27198950; PMCID: PMC4875564; DOI: 10.1016/j.sleep.2015.11.009;

Tsao CW, Lyass A, Larson MG, Levy D, Hamburg NM, Vita JA, Benjamin EJ, Mitchell GF, Vasan RS. Relation of Central Arterial Stiffness to Incident Heart Failure in the Community. J Am Heart Assoc. 2015 Nov; 4(11).View Related Profiles.

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PMID: 26597152; PMCID: PMC4845230; DOI: 10.1161/JAHA.115.002189;

Yin X, Levy D, Willinger C, Adourian A, Larson MG. Multiple imputation and analysis for high-dimensional incomplete proteomics data. Stat Med. 2016 Apr 15; 35(8):1315-26. PMID: 26565662; PMCID: PMC4777663; DOI: 10.1002/sim.6800;

Cheng S, McCabe EL, Larson MG, Merz AA, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Distinct Aspects of Left Ventricular Mechanical Function Are Differentially Associated With Cardiovascular Outcomes and All-Cause Mortality in the Community. J Am Heart Assoc. 2015 Oct; 4(10):e002071.View Related Profiles.

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PMID: 26508740; PMCID: PMC4845131; DOI: 10.1161/JAHA.115.002071;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Response to Letter Regarding Article, "Familial Clustering of Mitral Valve Prolapse in the Community". Circulation. 2015 Oct 6; 132(14):e187-8.View Related Profiles.

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PMID: 26438779; PMCID: PMC4620666; DOI: 10.1161/CIRCULATIONAHA.115.016788;

Andersson C, Lyass A, Larson MG, Robins SJ, Vasan RS. Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study. Diabetologia. 2015 Dec; 58(12):2774-80.View Related Profiles.

Larson, Martin
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PMID: 26409460; PMCID: PMC4631796; DOI: 10.1007/s00125-015-3762-x;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Erratum: Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:7317.View Related Profiles.

O'Donnell, Christopher
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PMID: 25993905; DOI: 10.1038/ncomms8317;

Schnabel RB, Yin X, Gona P, Larson MG, Beiser AS, McManus DD, Newton-Cheh C, Lubitz SA, Magnani JW, Ellinor PT, Seshadri S, Wolf PA, Vasan RS, Benjamin EJ, Levy D. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. Lancet. 2015 Jul 11; 386(9989):154-62.View Related Profiles.

Beiser, Alexa
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PMID: 25960110; PMCID: PMC4553037; DOI: 10.1016/S0140-6736(14)61774-8;

Andersson C, Enserro D, Larson MG, Xanthakis V, Vasan RS. Implications of the US cholesterol guidelines on eligibility for statin therapy in the community: comparison of observed and predicted risks in the Framingham Heart Study Offspring Cohort. J Am Heart Assoc. 2015 Apr; 4(4).View Related Profiles.

Larson, Martin
Xanthakis, Vanessa
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PMID: 25888372; PMCID: PMC4579932; DOI: 10.1161/JAHA.115.001888;

Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Distinct metabolomic signatures are associated with longevity in humans. Nat Commun. 2015; 6:6791.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
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PMID: 25864806; PMCID: PMC4396657; DOI: 10.1038/ncomms7791;

Fontes JD, Rahman F, Lacey S, Larson MG, Vasan RS, Benjamin EJ, Harris WS, Robins SJ. Red blood cell fatty acids and biomarkers of inflammation: a cross-sectional study in a community-based cohort. Atherosclerosis. 2015 Jun; 240(2):431-6.View Related Profiles.

Benjamin, Emelia
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PMID: 25897795; PMCID: PMC4511480; DOI: 10.1016/j.atherosclerosis.2015.03.043;

Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito JM, Yao C, Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE. Genome-wide identification of microRNA expression quantitative trait loci. Nat Commun. 2015; 6:6601.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
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Larson, Martin
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PMID: 25791433; PMCID: PMC4369777; DOI: 10.1038/ncomms7601;

Andersson C, Lyass A, Larson MG, Spartano NL, Vita JA, Benjamin EJ, Murabito JM, Esliger DW, Blease SJ, Hamburg NM, Mitchell GF, Vasan RS. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults. J Am Heart Assoc. 2015 Mar; 4(3):e001528.View Related Profiles.

Benjamin, Emelia
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PMID: 25792127; PMCID: PMC4392434; DOI: 10.1161/JAHA.114.001528;

Lubitz SA, Yin X, Rienstra M, Schnabel RB, Walkey AJ, Magnani JW, Rahman F, McManus DD, Tadros TM, Levy D, Vasan RS, Larson MG, Ellinor PT, Benjamin EJ. Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study. Circulation. 2015 May 12; 131(19):1648-55.View Related Profiles.

Walkey, Allan
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Larson, Martin
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Yin, Xiaoyan

PMID: 25769640; PMCID: PMC4430386; DOI: 10.1161/CIRCULATIONAHA.114.014058;

Long MT, Wang N, Larson MG, Mitchell GF, Palmisano J, Vasan RS, Hoffmann U, Speliotes EK, Vita JA, Benjamin EJ, Fox CS, Hamburg NM. Nonalcoholic fatty liver disease and vascular function: cross-sectional analysis in the Framingham heart study. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1284-91.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Long, Michelle
Hamburg, Naomi
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PMID: 25745056; PMCID: PMC4520415; DOI: 10.1161/ATVBAHA.114.305200;

Huan T, Rong J, Tanriverdi K, Meng Q, Bhattacharya A, McManus DD, Joehanes R, Assimes TL, McPherson R, Samani NJ, Erdmann J, Schunkert H, Courchesne P, Munson PJ, Johnson AD, O'Donnell CJ, Zhang B, Larson MG, Freedman JE, Levy D, Yang X. Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses. Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4):1011-21.View Related Profiles.

O'Donnell, Christopher
Larson, Martin

PMID: 25657313; PMCID: PMC4376567; DOI: 10.1161/ATVBAHA.114.305176;

Lieb W, Chen MH, Larson MG, Safa R, Teumer A, Baumeister SE, Lin H, Smith HM, Koch M, Lorbeer R, Völker U, Nauck M, Völzke H, Wallaschofski H, Sawyer DB, Vasan RS. Genome-wide association study for endothelial growth factors. Circ Cardiovasc Genet. 2015 Apr; 8(2):389-97.View Related Profiles.

Lin, Honghuang
Larson, Martin
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PMID: 25552591; PMCID: PMC4406801; DOI: 10.1161/CIRCGENETICS.114.000597;

Kaess BM, Harris WS, Lacey S, Larson MG, Hamburg NM, Vita JA, Robins SJ, Benjamin EJ, Mitchell GF, Vasan RS. The relation of red blood cell fatty acids with vascular stiffness, cardiac structure and left ventricular function: the Framingham Heart Study. Vasc Med. 2015 Feb; 20(1):5-13.View Related Profiles.

Kaess, Bernhard
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Vita, Joseph
Larson, Martin
Hamburg, Naomi
Robins, Sander
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PMID: 25520318; DOI: 10.1177/1358863X14560808;

Tintle NL, Pottala JV, Lacey S, Ramachandran V, Westra J, Rogers A, Clark J, Olthoff B, Larson M, Harris W, Shearer GC. A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. Prostaglandins Leukot Essent Fatty Acids. 2015 Mar; 94:65-72.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25500335; PMCID: PMC4339483; DOI: 10.1016/j.plefa.2014.11.007;

Cheng S, McCabe EL, Larson MG, Chen MH, Osypiuk E, Lehman BT, Stantchev P, Aragam J, Solomon SD, Benjamin EJ, Vasan RS. Left ventricular mechanical function: clinical correlates, heritability, and association with parental heart failure. Eur J Heart Fail. 2015 Jan; 17(1):44-50.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
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Larson, Martin
Ramachandran, Vasan

PMID: 25445300; PMCID: PMC5467740; DOI: 10.1002/ejhf.202;

Franklin SS, Gokhale SS, Chow VH, Larson MG, Levy D, Vasan RS, Mitchell GF, Wong ND. Does low diastolic blood pressure contribute to the risk of recurrent hypertensive cardiovascular disease events? The Framingham Heart Study. Hypertension. 2015 Feb; 65(2):299-305.View Related Profiles.

Levy, Daniel
Larson, Martin
Ramachandran, Vasan

PMID: 25421982; DOI: 10.1161/HYPERTENSIONAHA.114.04581;

Cooper LL, Rong J, Benjamin EJ, Larson MG, Levy D, Vita JA, Hamburg NM, Vasan RS, Mitchell GF. Components of hemodynamic load and cardiovascular events: the Framingham Heart Study. Circulation. 2015 Jan 27; 131(4):354-61; discussion 361.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
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PMID: 25416177; PMCID: PMC4308473; DOI: 10.1161/CIRCULATIONAHA.114.011357;

Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Hum Genet. 2015 Feb; 134(2):169-79.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 25381465; PMCID: PMC4303043; DOI: 10.1007/s00439-014-1505-6;

Delling FN, Rong J, Larson MG, Lehman B, Osypiuk E, Stantchev P, Slaugenhaupt SA, Benjamin EJ, Levine RA, Vasan RS. Familial clustering of mitral valve prolapse in the community. Circulation. 2015 Jan 20; 131(3):263-8.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
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Larson, Martin
Ramachandran, Vasan

PMID: 25361552; PMCID: PMC4301989; DOI: 10.1161/CIRCULATIONAHA.114.012594;

Andersson C, Gislason GH, Hlatky MA, Søndergaard KB, Pallisgaard J, Smith JG, Vasan RS, Larson MG, Jensen PF, Køber L, Torp-Pedersen C. A risk score for predicting 30-day mortality in heart failure patients undergoing non-cardiac surgery. Eur J Heart Fail. 2014 Dec; 16(12):1310-6.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 25359203; DOI: 10.1002/ejhf.182;

Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community. Clin Chem. 2014 Nov; 60(11):1402-8.View Related Profiles.

Gopal, Deepa
Ho, Jennifer
Polak, Joseph
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 25237063; PMCID: PMC4376479; DOI: 10.1373/clinchem.2014.227116;

Lieb W, Gona P, Larson MG, Aragam J, Zile MR, Cheng S, Benjamin EJ, Vasan RS. The natural history of left ventricular geometry in the community: clinical correlates and prognostic significance of change in LV geometric pattern. JACC Cardiovasc Imaging. 2014 Sep; 7(9):870-8.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
Ramachandran, Vasan

PMID: 25129518; PMCID: PMC4163746; DOI: 10.1016/j.jcmg.2014.05.008;

Torjesen AA, Wang N, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Forward and backward wave morphology and central pressure augmentation in men and women in the Framingham Heart Study. Hypertension. 2014 Aug; 64(2):259-65.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
Ramachandran, Vasan

PMID: 24866142; PMCID: PMC4184952; DOI: 10.1161/HYPERTENSIONAHA.114.03371;

Kwan JS, Hsu YH, Cheung CL, Dupuis J, Saint-Pierre A, Eriksson J, Handelman SK, Aragaki A, Karasik D, Pramstaller PP, Kooperberg C, Lacroix AZ, Larson MG, Lau KS, Lorentzon M, Pichler I, Sham PC, Taliun D, Vandenput L, Kiel DP, Hicks AA, Jackson RD, Ohlsson C, Benjamin EJ, Kung AW. Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Hum Mol Genet. 2014 Dec 15; 23(24):6684-93.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Larson, Martin

PMID: 25080503; PMCID: PMC4240210; DOI: 10.1093/hmg/ddu386;

Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2100-5.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Ho, Jennifer
Larson, Martin

PMID: 25060794; PMCID: PMC4142677; DOI: 10.1161/ATVBAHA.114.303579;

Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace. 2014 Oct; 16(10):1426-33.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Larson, Martin
Pencina, Michael
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PMID: 25037055; PMCID: PMC4197895; DOI: 10.1093/europace/euu175;

Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 3; 95(1):49-65.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24975945; PMCID: PMC4085637; DOI: 10.1016/j.ajhg.2014.06.002;

Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikäinen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai ÅT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polašek O, Wright AF, Griffin M, Daly MJ, Arnar DO, Hólm H, Thorsteinsdottir U, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O'Donnell CJ, Yin X, Bobbo M, D'Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jöckel KH, Kälsch H, Nöthen MM, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, Prucha H, Sinner MF, Waldenberger M, de Boer RA, Franke L, van der Vleuten PA, Beckmann BM, Martens E, Bardai A, Hofman N, Wilde AA, Behr ER, Dalageorgou C, Giudicessi JR, Medeiros-Domingo A, Barc J, Kyndt F, Probst V, Ghidoni A, Insolia R, Hamilton RM, Scherer SW, Brandimarto J, Margulies K, Moravec CE, del Greco M F, Fuchsberger C, O'Connell JR, Lee WK, Watt GC, Campbell H, Wild SH, El Mokhtari NE, Frey N, Asselbergs FW, Mateo Leach I, Navis G, van den Berg MP, van Veldhuisen DJ, Kellis M, Krijthe BP, Franco OH, Hofman A, Kors JA, Uitterlinden AG, Witteman JC, Kedenko L, Lamina C, Oostra BA, Abecasis GR, Lakatta EG, Mulas A, Orrú M, Schlessinger D, Uda M, Markus MR, Völker U, Snieder H, Spector TD, Ärnlöv J, Lind L, Sundström J, Syvänen AC, Kivimaki M, Kähönen M, Mononen N, Raitakari OT, Viikari JS, Adamkova V, Kiechl S, Brion M, Nicolaides AN, Paulweber B, Haerting J, Dominiczak AF, Nyberg F, Whincup PH, Hingorani AD, Schott JJ, Bezzina CR, Ingelsson E, Ferrucci L, Gasparini P, Wilson JF, Rudan I, Franke A, Mühleisen TW, Pramstaller PP, Lehtimäki TJ, Paterson AD, Parsa A, Liu Y, van Duijn CM, Siscovick DS, Gudnason V, Jamshidi Y, Salomaa V, Felix SB, Sanna S, Ritchie MD, Stricker BH, Stefansson K, Boyer LA, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet. 2014 Aug; 46(8):826-36.View Related Profiles.

O'Donnell, Christopher
Larson, Martin

PMID: 24952745; PMCID: PMC4124521; DOI: 10.1038/ng.3014;

Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 3; 95(1):24-38.View Related Profiles.

Larson, Martin
Ramachandran, Vasan

PMID: 24954895; PMCID: PMC4085636; DOI: 10.1016/j.ajhg.2014.05.010;

McMahon GM, Olden M, Garnaas M, Yang Q, Liu X, Hwang SJ, Larson MG, Goessling W, Fox CS. Sequencing of LRP2 reveals multiple rare variants associated with urinary trefoil factor-3. J Am Soc Nephrol. 2014 Dec; 25(12):2896-905.View Related Profiles.

Larson, Martin
Yang, Qiong
Hwang, Shih-Jen

PMID: 24876117; PMCID: PMC4243354; DOI: 10.1681/ASN.2013111240;

Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, Morris A, Pendergrass SA, Sun YV, Ritchie MD, Vaez A, Lin H, Ligthart S, Marullo L, Rohde R, Shao Y, Ziegler MA, Im HK, Schnabel RB, Jørgensen T, Jørgensen ME, Hansen T, Pedersen O, Stolk RP, Snieder H, Hofman A, Uitterlinden AG, Franco OH, Ikram MA, Richards JB, Rotimi C, Wilson JG, Lange L, Ganesh SK, Nalls M, Rasmussen-Torvik LJ, Pankow JS, Coresh J, Tang W, Linda Kao WH, Boerwinkle E, Morrison AC, Ridker PM, Becker DM, Rotter JI, Kardia SL, Loos RJ, Larson MG, Hsu YH, Province MA, Tracy R, Voight BF, Vaidya D, O'Donnell CJ, Benjamin EJ, Alizadeh BZ, Prokopenko I, Meigs JB, Borecki IB. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Lin, Honghuang
Dupuis, Josee
Larson, Martin

PMID: 24981077; PMCID: PMC4122618; DOI: 10.1016/j.ymgme.2014.04.007;

Ho JE, Larson MG, Ghorbani A, Cheng S, Coglianese EE, Vasan RS, Wang TJ. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. J Am Heart Assoc. 2014 Jun; 3(3):e000668.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 24811610; PMCID: PMC4309047; DOI: 10.1161/JAHA.113.000668;

Lin H, Yin X, Lunetta KL, Dupuis J, McManus DD, Lubitz SA, Magnani JW, Joehanes R, Munson PJ, Larson MG, Levy D, Ellinor PT, Benjamin EJ. Whole blood gene expression and atrial fibrillation: the Framingham Heart Study. PLoS One. 2014; 9(5):e96794.View Related Profiles.

Levy, Daniel
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Lin, Honghuang
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PMID: 24805109; PMCID: PMC4013062; DOI: 10.1371/journal.pone.0096794;

Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014 Nov 7; 35(42):2972-9.View Related Profiles.

Ho, Jennifer
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PMID: 24742886; PMCID: PMC4223610; DOI: 10.1093/eurheartj/ehu153;

Pottala JV, Djira GD, Espeland MA, Ye J, Larson MG, Harris WS. Structural equation modeling for analyzing erythrocyte fatty acids in Framingham. Comput Math Methods Med. 2014; 2014:160520. PMID: 24959197; PMCID: PMC4052884; DOI: 10.1155/2014/160520;

Ho JE, Yin X, Levy D, Vasan RS, Magnani JW, Ellinor PT, McManus DD, Lubitz SA, Larson MG, Benjamin EJ. Galectin 3 and incident atrial fibrillation in the community. Am Heart J. 2014 May; 167(5):729-34.e1.View Related Profiles.

Benjamin, Emelia
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PMID: 24766984; PMCID: PMC4007212; DOI: 10.1016/j.ahj.2014.02.009;

Yin X, Subramanian S, Hwang SJ, O'Donnell CJ, Fox CS, Courchesne P, Muntendam P, Gordon N, Adourian A, Juhasz P, Larson MG, Levy D. Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):939-45.View Related Profiles.

O'Donnell, Christopher
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PMID: 24526693; PMCID: PMC4061732; DOI: 10.1161/ATVBAHA.113.302918;

Beaulieu LM, Lin E, Mick E, Koupenova M, Weinberg EO, Kramer CD, Genco CA, Tanriverdi K, Larson MG, Benjamin EJ, Freedman JE. Interleukin 1 receptor 1 and interleukin 1ß regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arterioscler Thromb Vasc Biol. 2014 Mar; 34(3):552-64.View Related Profiles.

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PMID: 24458711; PMCID: PMC4070375; DOI: 10.1161/ATVBAHA.113.302700;

McManus DD, Lin H, Tanriverdi K, Quercio M, Yin X, Larson MG, Ellinor PT, Levy D, Freedman JE, Benjamin EJ. Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study. Heart Rhythm. 2014 Apr; 11(4):663-9.View Related Profiles.

Benjamin, Emelia
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PMID: 24444445; PMCID: PMC4219255; DOI: 10.1016/j.hrthm.2014.01.018;

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 7; 19(1):96-108.View Related Profiles.

Larson, Martin
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PMID: 24411942; PMCID: PMC4017355; DOI: 10.1016/j.cmet.2013.12.003;

Xanthakis V, Larson MG, Wollert KC, Aragam J, Cheng S, Ho J, Coglianese E, Levy D, Colucci WS, Michael Felker G, Benjamin EJ, Januzzi JL, Wang TJ, Vasan RS. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. J Am Heart Assoc. 2013; 2(6):e000399.View Related Profiles.

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PMID: 24200688; PMCID: PMC3886765; DOI: 10.1161/JAHA.113.000399;

Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014 Jan; 27(1):17-23.View Related Profiles.

Benjamin, Emelia
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PMID: 24206636; PMCID: PMC4239996; DOI: 10.1016/j.echo.2013.09.015;

Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014 Jan; 167(1):109-115.e2.View Related Profiles.

Benjamin, Emelia
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PMID: 24332149; PMCID: PMC3884900; DOI: 10.1016/j.ahj.2013.10.003;

Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct 1; 123(10):4309-17.View Related Profiles.

O'Donnell, Christopher
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PMID: 24091325; PMCID: PMC3784523; DOI: 10.1172/JCI64801;

Kaess BM, Gona P, Larson MG, Cheng S, Aragam J, Kenchaiah S, Benjamin EJ, Vasan RS. Secular trends in echocardiographic left ventricular mass in the community: the Framingham Heart Study. Heart. 2013 Nov; 99(22):1693-8.View Related Profiles.

Kaess, Bernhard
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Larson, Martin
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PMID: 24041649; PMCID: PMC4139052; DOI: 10.1136/heartjnl-2013-304600;

Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013 Oct 1; 123(10):4208-18.View Related Profiles.

O'Donnell, Christopher
Lin, Honghuang
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Chen, Ming-Huei
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PMID: 23999434; PMCID: PMC3784527; DOI: 10.1172/JCI67119;

Lubitz SA, Moser C, Sullivan L, Rienstra M, Fontes JD, Villalon ML, Pai M, McManus DD, Schnabel RB, Magnani JW, Yin X, Levy D, Pencina MJ, Larson MG, Ellinor PT, Benjamin EJ. Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community. J Am Heart Assoc. 2013 Oct; 2(5):e000126.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
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PMID: 24002369; PMCID: PMC3835216; DOI: 10.1161/JAHA.113.000126;

O'Seaghdha CM, Hwang SJ, Larson MG, Meigs JB, Vasan RS, Fox CS. Analysis of a urinary biomarker panel for incident kidney disease and clinical outcomes. J Am Soc Nephrol. 2013 Nov; 24(11):1880-8.View Related Profiles.

Larson, Martin
Hwang, Shih-Jen
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PMID: 23990678; PMCID: PMC3810081; DOI: 10.1681/ASN.2013010019;

McManus DD, Beaulieu LM, Mick E, Tanriverdi K, Larson MG, Keaney JF, Benjamin EJ, Freedman JE. Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk. Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11):2666-73.View Related Profiles.

Benjamin, Emelia
Freedman, Jane
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Larson, Martin

PMID: 23968978; PMCID: PMC4289138; DOI: 10.1161/ATVBAHA.112.301112;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Reproducibility of speckle-tracking-based strain measures of left ventricular function in a community-based study. J Am Soc Echocardiogr. 2013 Nov; 26(11):1258-1266.e2.View Related Profiles.

Benjamin, Emelia
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PMID: 23953701; PMCID: PMC3812381; DOI: 10.1016/j.echo.2013.07.002;

Tsao CW, Seshadri S, Beiser AS, Westwood AJ, Decarli C, Au R, Himali JJ, Hamburg NM, Vita JA, Levy D, Larson MG, Benjamin EJ, Wolf PA, Vasan RS, Mitchell GF. Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology. 2013 Sep 10; 81(11):984-91.View Related Profiles.

Beiser, Alexa
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Himali, Jayandra
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Larson, Martin
Hamburg, Naomi
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 23935179; PMCID: PMC3888200; DOI: 10.1212/WNL.0b013e3182a43e1c;

Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS. Age- and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study. Circ Cardiovasc Imaging. 2013 Sep; 6(5):692-9.View Related Profiles.

Benjamin, Emelia
Osypiuk, Ewa
Aragam, Jayashri
Larson, Martin
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PMID: 23917618; PMCID: PMC3856433; DOI: 10.1161/CIRCIMAGING.112.000627;

Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS. Biomarkers of cardiovascular stress and incident chronic kidney disease. Clin Chem. 2013 Nov; 59(11):1613-20.View Related Profiles.

Ho, Jennifer
Larson, Martin
Hwang, Shih-Jen
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PMID: 23873716; PMCID: PMC3972213; DOI: 10.1373/clinchem.2013.205716;

Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab. 2013 Jul 2; 18(1):130-43.View Related Profiles.

O'Donnell, Christopher
Ho, Jennifer
Larson, Martin
Chen, Ming-Huei
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PMID: 23823483; PMCID: PMC3973158; DOI: 10.1016/j.cmet.2013.06.013;

Ho JE, Larson MG, Ghorbani A, Cheng S, Vasan RS, Wang TJ, Januzzi JL. Soluble ST2 predicts elevated SBP in the community. J Hypertens. 2013 Jul; 31(7):1431-6; discussion 1436.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 23615326; PMCID: PMC3986262; DOI: 10.1097/HJH.0b013e3283611bdf;

Britton KA, Wang N, Palmisano J, Corsini E, Schlett CL, Hoffmann U, Larson MG, Vasan RS, Vita JA, Mitchell GF, Benjamin EJ, Hamburg NM, Fox CS. Thoracic periaortic and visceral adipose tissue and their cross-sectional associations with measures of vascular function. Obesity (Silver Spring). 2013 Jul; 21(7):1496-503.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
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PMID: 23754461; PMCID: PMC3742564; DOI: 10.1002/oby.20166;

Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. A combined epidemiologic and metabolomic approach improves CKD prediction. J Am Soc Nephrol. 2013 Jul; 24(8):1330-8.View Related Profiles.

Larson, Martin
Yang, Qiong
Elmariah, Sammy
Ramachandran, Vasan

PMID: 23687356; PMCID: PMC3736702; DOI: 10.1681/ASN.2012101006;

Schnabel RB, Yin X, Larson MG, Yamamoto JF, Fontes JD, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Murabito JM, Vasan RS, Benjamin EJ. Multiple inflammatory biomarkers in relation to cardiovascular events and mortality in the community. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1728-33.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Larson, Martin
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Yin, Xiaoyan

PMID: 23640499; PMCID: PMC3753537; DOI: 10.1161/ATVBAHA.112.301174;

Chami HA, Fontes JD, Vasan RS, Keaney JF, O'Connor GT, Larson MG, Benjamin EJ, Gottlieb DJ. Vascular inflammation and sleep disordered breathing in a community-based cohort. Sleep. 2013 May; 36(5):763-768C.View Related Profiles.

Benjamin, Emelia
O'Connor, George
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PMID: 23633759; PMCID: PMC3622647; DOI: 10.5665/sleep.2644;

Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS. Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013 Jul; 229(1):228-33.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 23701996; PMCID: PMC3984590; DOI: 10.1016/j.atherosclerosis.2013.04.017;

Alonso A, Krijthe BP, Aspelund T, Stepas KA, Pencina MJ, Moser CB, Sinner MF, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Agarwal SK, McManus DD, Ellinor PT, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Soliman EZ, Stricker BH, Gudnason V, Heckbert SR, Benjamin EJ. Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium. J Am Heart Assoc. 2013 Apr; 2(2):e000102.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Larson, Martin
Pencina, Michael

PMID: 23537808; PMCID: PMC3647274; DOI: 10.1161/JAHA.112.000102;

Ho JE, Larson MG, Vasan RS, Ghorbani A, Cheng S, Rhee EP, Florez JC, Clish CB, Gerszten RE, Wang TJ. Metabolite profiles during oral glucose challenge. Diabetes. 2013 Aug; 62(8):2689-98.View Related Profiles.

Ho, Jennifer
Larson, Martin
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PMID: 23382451; PMCID: PMC3717862; DOI: 10.2337/db12-0754;

Fontes JD, Yamamoto JF, Larson MG, Wang N, Dallmeier D, Rienstra M, Schnabel RB, Vasan RS, Keaney JF, Benjamin EJ. Clinical correlates of change in inflammatory biomarkers: The Framingham Heart Study. Atherosclerosis. 2013 May; 228(1):217-23.View Related Profiles.

Dallmeier Rojas, Dhayana
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PMID: 23489346; PMCID: PMC3650714; DOI: 10.1016/j.atherosclerosis.2013.01.019;

Lam CS, Gona P, Larson MG, Aragam J, Lee DS, Mitchell GF, Levy D, Cheng S, Benjamin EJ, Vasan RS. Aortic root remodeling and risk of heart failure in the Framingham Heart study. JACC Heart Fail. 2013 Feb; 1(1):79-83.View Related Profiles.

Benjamin, Emelia
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PMID: 23998002; PMCID: PMC3755769; DOI: 10.1016/j.jchf.2012.10.003;

Liu C, Dupuis J, Larson MG, Levy D. Association testing of the mitochondrial genome using pedigree data. Genet Epidemiol. 2013 Apr; 37(3):239-47.View Related Profiles.

Liu, Chunyu
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PMID: 23319385; PMCID: PMC4171957; DOI: 10.1002/gepi.21706;

Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ. Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013 Feb 21; 121(8):e50-6.View Related Profiles.

O'Donnell, Christopher
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PMID: 23287867; PMCID: PMC3578962; DOI: 10.1182/blood-2012-05-424846;

Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, Levy D. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013 Mar; 6(2):279-86.View Related Profiles.

Ho, Jennifer
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PMID: 23271790; PMCID: PMC3705220; DOI: 10.1161/CIRCHEARTFAILURE.112.972828;

Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q. Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. PLoS One. 2012; 7(12):e51589.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 23284720; PMCID: PMC3524237; DOI: 10.1371/journal.pone.0051589;

Franzini M, Fornaciari I, Rong J, Larson MG, Passino C, Emdin M, Paolicchi A, Vasan RS. Correlates and reference limits of plasma gamma-glutamyltransferase fractions from the Framingham Heart Study. Clin Chim Acta. 2013 Feb 18; 417:19-25.View Related Profiles.

Larson, Martin
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PMID: 23247050; PMCID: PMC4154585; DOI: 10.1016/j.cca.2012.12.002;

Coglianese EE, Larson MG, Vasan RS, Ho JE, Ghorbani A, McCabe EL, Cheng S, Fradley MG, Kretschman D, Gao W, O'Connor G, Wang TJ, Januzzi JL. Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. Clin Chem. 2012 Dec; 58(12):1673-81.View Related Profiles.

O'Connor, George
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PMID: 23065477; PMCID: PMC3557515; DOI: 10.1373/clinchem.2012.192153;

Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem. 2012 Nov; 58(11):1582-91.View Related Profiles.

Ho, Jennifer
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PMID: 22997280; PMCID: PMC4150608 ; DOI: 10.1373/clinchem.2012.190322;

Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Aortic stiffness, blood pressure progression, and incident hypertension. JAMA. 2012 Sep 5; 308(9):875-81.View Related Profiles.

Kaess, Bernhard
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PMID: 22948697; PMCID: PMC3594687; DOI: 10.1001/2012.jama.10503;

Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012 Oct 2; 60(14):1249-56.View Related Profiles.

Liu, Chunyu
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PMID: 22939561; PMCID: PMC3512095; DOI: 10.1016/j.jacc.2012.04.053;

Dallmeier D, Larson MG, Wang N, Fontes JD, Benjamin EJ, Fox CS. Addition of inflammatory biomarkers did not improve diabetes prediction in the community: the framingham heart study. J Am Heart Assoc. 2012 Aug; 1(4):e000869.View Related Profiles.

Dallmeier Rojas, Dhayana
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PMID: 23130155; PMCID: PMC3487343; DOI: 10.1161/JAHA.112.000869;

Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S, Ho JE, Fradley MG, Ghorbani A, Xanthakis V, Kempf T, Benjamin EJ, Levy D, Vasan RS, Januzzi JL. Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study. Circulation. 2012 Sep 25; 126(13):1596-604.View Related Profiles.

Benjamin, Emelia
Ho, Jennifer
Larson, Martin
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PMID: 22907935; PMCID: PMC3656719; DOI: 10.1161/CIRCULATIONAHA.112.129437;

Noseworthy PA, Peloso GM, Hwang SJ, Larson MG, Levy D, O'Donnell CJ, Newton-Cheh C. QT interval and long-term mortality risk in the Framingham Heart Study. Ann Noninvasive Electrocardiol. 2012 Oct; 17(4):340-8.View Related Profiles.

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PMID: 23094880; PMCID: PMC3481183; DOI: 10.1111/j.1542-474X.2012.00535.x;

Dallmeier D, Larson MG, Vasan RS, Keaney JF, Fontes JD, Meigs JB, Fox CS, Benjamin EJ. Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study. Diabetol Metab Syndr. 2012; 4(1):28.View Related Profiles.

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PMID: 22716219; PMCID: PMC3547735; DOI: 10.1186/1758-5996-4-28;

Harris WS, Pottala JV, Lacey SM, Vasan RS, Larson MG, Robins SJ. Clinical correlates and heritability of erythrocyte eicosapentaenoic and docosahexaenoic acid content in the Framingham Heart Study. Atherosclerosis. 2012 Dec; 225(2):425-31.View Related Profiles.

Larson, Martin
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PMID: 22727409; PMCID: PMC3593234; DOI: 10.1016/j.atherosclerosis.2012.05.030;

Harris WS, Pottala JV, Vasan RS, Larson MG, Robins SJ. Changes in erythrocyte membrane trans and marine fatty acids between 1999 and 2006 in older Americans. J Nutr. 2012 Jul; 142(7):1297-303.View Related Profiles.

Larson, Martin
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PMID: 22623386; PMCID: PMC3374668; DOI: 10.3945/jn.112.158295;

Thanassoulis G, Lyass A, Benjamin EJ, Larson MG, Vita JA, Levy D, Hamburg NM, Widlansky ME, O'Donnell CJ, Mitchell GF, Vasan RS. Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study. Circulation. 2012 Jun 12; 125(23):2836-43.View Related Profiles.

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PMID: 22572915; PMCID: PMC3636551; DOI: 10.1161/CIRCULATIONAHA.111.063933;

Fedorowski A, Franceschini N, Brody J, Liu C, Verwoert GC, Boerwinkle E, Couper D, Rice KM, Rotter JI, Mattace-Raso F, Uitterlinden A, Hofman A, Almgren P, Sjögren M, Hedblad B, Larson MG, Newton-Cheh C, Wang TJ, Rose KM, Psaty BM, Levy D, Witteman J, Melander O. Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium. Eur Heart J. 2012 Sep; 33(18):2331-41. PMID: 22504314; PMCID: PMC3442958; DOI: 10.1093/eurheartj/ehs058;

Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation. 2012 May 8; 125(18):2222-31.View Related Profiles.

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PMID: 22496159; PMCID: PMC3376658; DOI: 10.1161/CIRCULATIONAHA.111.067827;

Ellis JW, Chen MH, Foster MC, Liu CT, Larson MG, de Boer I, Köttgen A, Parsa A, Bochud M, Böger CA, Kao L, Fox CS, O'Seaghdha CM. Validated SNPs for eGFR and their associations with albuminuria. Hum Mol Genet. 2012 Jul 15; 21(14):3293-8.View Related Profiles.

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O'Seaghdha CM, Hwang SJ, Vasan RS, Larson MG, Hoffmann U, Wang TJ, Fox CS. Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study. BMC Endocr Disord. 2012; 12:3.View Related Profiles.

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Zachariah JP, Xanthakis V, Larson MG, Vita JA, Sullivan LM, Smith HM, Safa R, Peng X, Hamburg N, Levy D, Sawyer DB, Mitchell GF, Vasan RS. Circulating vascular growth factors and central hemodynamic load in the community. Hypertension. 2012 Apr; 59(4):773-9.View Related Profiles.

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Kaess BM, Pedley A, Massaro JM, Larson MG, Corsini E, Hoffmann U, Smith HM, Sawyer DB, Vasan RS, Fox CS. Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study. J Clin Endocrinol Metab. 2012 Mar; 97(3):987-94.View Related Profiles.

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PMID: 22170711; PMCID: PMC3319207; DOI: 10.1210/jc.2011-2310;

Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Ikram MA, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012 Feb 1; 5(1):81-90.View Related Profiles.

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Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM. Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2012 Jan; 220(1):145-50.View Related Profiles.

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Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2012 Jan; 33(2):238-51.View Related Profiles.

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PMID: 22003152; PMCID: PMC3258449; DOI: 10.1093/eurheartj/ehr372;

Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, König IR, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, Mitchell GF, Smith NL, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Oct; 43(10):1005-11.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
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PMID: 21909110; PMCID: PMC3445021; DOI: 10.1038/ng.922;

Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Oct 6; 478(7367):103-9.View Related Profiles.

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Chen, Ming-Huei
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PMID: 21909115; PMCID: PMC3340926; DOI: 10.1038/nature10405;

Fradley MG, Larson MG, Cheng S, McCabe E, Coglianese E, Shah RV, Levy D, Vasan RS, Wang TJ. Reference limits for N-terminal-pro-B-type natriuretic peptide in healthy individuals (from the Framingham Heart Study). Am J Cardiol. 2011 Nov 1; 108(9):1341-5.View Related Profiles.

Larson, Martin
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PMID: 21864812; PMCID: PMC3209520; DOI: 10.1016/j.amjcard.2011.06.057;

Khan AM, Cheng S, Magnusson M, Larson MG, Newton-Cheh C, McCabe EL, Coviello AD, Florez JC, Fox CS, Levy D, Robins SJ, Arora P, Bhasin S, Lam CS, Vasan RS, Melander O, Wang TJ. Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies. J Clin Endocrinol Metab. 2011 Oct; 96(10):3242-9.View Related Profiles.

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PMID: 21849523; PMCID: PMC3200240; DOI: 10.1210/jc.2011-1182;

Rienstra M, Cheng S, Larson MG, McCabe EL, Booth SL, Jacques PF, Lubitz SA, Yin X, Levy D, Magnani JW, Ellinor PT, Benjamin EJ, Wang TJ. Vitamin D status is not related to development of atrial fibrillation in the community. Am Heart J. 2011 Sep; 162(3):538-41.View Related Profiles.

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PMID: 21884873; PMCID: PMC3170821; DOI: 10.1016/j.ahj.2011.06.013;

Chen MH, Liu X, Wei F, Larson MG, Fox CS, Vasan RS, Yang Q. A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees. Genet Epidemiol. 2011 Nov; 35(7):650-7.View Related Profiles.

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PMID: 21818773; PMCID: PMC3197768; DOI: 10.1002/gepi.20614;

Lam CS, Cheng S, Choong K, Larson MG, Murabito JM, Newton-Cheh C, Bhasin S, McCabe EL, Miller KK, Redfield MM, Vasan RS, Coviello AD, Wang TJ. Influence of sex and hormone status on circulating natriuretic peptides. J Am Coll Cardiol. 2011 Aug 2; 58(6):618-26.View Related Profiles.

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PMID: 21798425; PMCID: PMC3170816; DOI: 10.1016/j.jacc.2011.03.042;

Cheng S, Fox CS, Larson MG, Massaro JM, McCabe EL, Khan AM, Levy D, Hoffmann U, O'Donnell CJ, Miller KK, Newton-Cheh C, Coviello AD, Bhasin S, Vasan RS, Wang TJ. Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals. Am J Cardiol. 2011 Oct 1; 108(7):979-84.View Related Profiles.

Coviello, Andrea
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PMID: 21813106; PMCID: PMC3175269; DOI: 10.1016/j.amjcard.2011.05.033;

Jefferson AL, Massaro JM, Beiser AS, Seshadri S, Larson MG, Wolf PA, Au R, Benjamin EJ. Inflammatory markers and neuropsychological functioning: the Framingham Heart Study. Neuroepidemiology. 2011; 37(1):21-30.View Related Profiles.

Beiser, Alexa
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PMID: 21757961; PMCID: PMC3142099; DOI: 10.1159/000328864;

Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ. Genetic and clinical correlates of early-outgrowth colony-forming units. Circ Cardiovasc Genet. 2011 Jun; 4(3):296-304.View Related Profiles.

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PMID: 21493818; PMCID: PMC3339257; DOI: 10.1161/CIRCGENETICS.110.958470;

Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC, Launer LJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, Caulfield M, van Duijn CM, Ridker PM, Munroe PB, Levy D. Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension. 2011 May; 57(5):903-10. PMID: 21444836; PMCID: PMC3099407; DOI: 10.1161/HYPERTENSIONAHA.110.158667;

Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE. Metabolite profiles and the risk of developing diabetes. Nat Med. 2011 Apr; 17(4):448-53.View Related Profiles.

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PMID: 21423183; PMCID: PMC3126616; DOI: 10.1038/nm.2307;

Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE. Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. J Clin Invest. 2011 Apr; 121(4):1402-11.View Related Profiles.

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PMID: 21403394; PMCID: PMC3069773; DOI: 10.1172/JCI44442;

Lieb W, Pencina MJ, Jacques PF, Wang TJ, Larson MG, Levy D, Kannel WB, Vasan RS. Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community. Eur J Cardiovasc Prev Rehabil. 2011 Aug; 18(4):664-73.View Related Profiles.

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PMID: 21450637; PMCID: PMC3179529; DOI: 10.1177/1741826710389406;

Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, Paré G, Naitza S, Rudock ME, Surakka I, de Geus EJ, Alizadeh BZ, Guralnik J, Shuldiner A, Tanaka T, Zee RY, Schnabel RB, Nambi V, Kavousi M, Ripatti S, Nauck M, Smith NL, Smith AV, Sundvall J, Scheet P, Liu Y, Ruokonen A, Rose LM, Larson MG, Hoogeveen RC, Freimer NB, Teumer A, Tracy RP, Launer LJ, Buring JE, Yamamoto JF, Folsom AR, Sijbrands EJ, Pankow J, Elliott P, Keaney JF, Sun W, Sarin AP, Fontes JD, Badola S, Astor BC, Hofman A, Pouta A, Werdan K, Greiser KH, Kuss O, Meyer zu Schwabedissen HE, Thiery J, Jamshidi Y, Nolte IM, Soranzo N, Spector TD, Völzke H, Parker AN, Aspelund T, Bates D, Young L, Tsui K, Siscovick DS, Guo X, Rotter JI, Uda M, Schlessinger D, Rudan I, Hicks AA, Penninx BW, Thorand B, Gieger C, Coresh J, Willemsen G, Harris TB, Uitterlinden AG, Järvelin MR, Rice K, Radke D, Salomaa V, Willems van Dijk K, Boerwinkle E, Vasan RS, Ferrucci L, Gibson QD, Bandinelli S, Snieder H, Boomsma DI, Xiao X, Campbell H, Hayward C, Pramstaller PP, van Duijn CM, Peltonen L, Psaty BM, Gudnason V, Ridker PM, Homuth G, Koenig W, Ballantyne CM, Witteman JC, Benjamin EJ, Perola M, Chasman DI. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8.View Related Profiles.

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Dupuis, Josee
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PMID: 21300955; PMCID: PMC3147232; DOI: 10.1161/CIRCULATIONAHA.110.948570;

Hamburg NM, Palmisano J, Larson MG, Sullivan LM, Lehman BT, Vasan RS, Levy D, Mitchell GF, Vita JA, Benjamin EJ. Relation of brachial and digital measures of vascular function in the community: the Framingham heart study. Hypertension. 2011 Mar; 57(3):390-6.View Related Profiles.

Benjamin, Emelia
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PMID: 21263120; PMCID: PMC3049726; DOI: 10.1161/HYPERTENSIONAHA.110.160812;

Lubitz SA, Yin X, Fontes JD, Magnani JW, Rienstra M, Pai M, Villalon ML, Vasan RS, Pencina MJ, Levy D, Larson MG, Ellinor PT, Benjamin EJ. Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA. 2010 Nov 24; 304(20):2263-9.View Related Profiles.

Benjamin, Emelia
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PMID: 21076174; PMCID: PMC3073054; DOI: 10.1001/jama.2010.1690;

Lee DS, Gona P, Albano I, Larson MG, Benjamin EJ, Levy D, Kannel WB, Vasan RS. A systematic assessment of causes of death after heart failure onset in the community: impact of age at death, time period, and left ventricular systolic dysfunction. Circ Heart Fail. 2011 Jan; 4(1):36-43.View Related Profiles.

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PMID: 21071547; PMCID: PMC3243964; DOI: 10.1161/CIRCHEARTFAILURE.110.957480;

Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, Meigs JB, Levy D, Wang TJ, Jacques PF, Benjamin EJ, Vasan RS. A multi-marker approach to predict incident CKD and microalbuminuria. J Am Soc Nephrol. 2010 Dec; 21(12):2143-9.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 20966127; PMCID: PMC3014027; DOI: 10.1681/ASN.2010010085;

Velagaleti RS, Gona P, Larson MG, Wang TJ, Levy D, Benjamin EJ, Selhub J, Jacques PF, Meigs JB, Tofler GH, Vasan RS. Multimarker approach for the prediction of heart failure incidence in the community. Circulation. 2010 Oct 26; 122(17):1700-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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Ramachandran, Vasan

PMID: 20937976; PMCID: PMC2993157; DOI: 10.1161/CIRCULATIONAHA.109.929661;

Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, Grove ML, Li M, Linda Kao WH, Chonchol M, Haritunians T, Li G, Lumley T, Psaty BM, Shlipak M, Hwang SJ, Larson MG, O'Donnell CJ, Upadhyay A, van Duijn CM, Hofman A, Rivadeneira F, Stricker B, Uitterlinden AG, Paré G, Parker AN, Ridker PM, Siscovick DS, Gudnason V, Witteman JC, Fox CS, Coresh J. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010 Dec; 3(6):523-30.View Related Profiles.

Upadhyay, Ashish
O'Donnell, Christopher
Larson, Martin
Chen, Ming-Huei
Glazer, Nicole
Yang, Qiong
Hwang, Shih-Jen

PMID: 20884846; PMCID: PMC3371395; DOI: 10.1161/CIRCGENETICS.109.934455;

Lam CS, Liu X, Yang Q, Larson MG, Pencina MJ, Aragam J, Redfield MM, Benjamin EJ, Vasan RS. Familial aggregation of left ventricular geometry and association with parental heart failure: the Framingham Heart Study. Circ Cardiovasc Genet. 2010 Dec; 3(6):492-8.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
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Pencina, Michael
Yang, Qiong
Ramachandran, Vasan

PMID: 20884845; PMCID: PMC3785074; DOI: 10.1161/CIRCGENETICS.110.941088;

Mitchell GF, Wang N, Palmisano JN, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS. Hemodynamic correlates of blood pressure across the adult age spectrum: noninvasive evaluation in the Framingham Heart Study. Circulation. 2010 Oct 5; 122(14):1379-86.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hamburg, Naomi
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PMID: 20855656; PMCID: PMC2981604; DOI: 10.1161/CIRCULATIONAHA.109.914507;

Cheng S, Cohen KS, Shaw SY, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ. Association of colony-forming units with coronary artery and abdominal aortic calcification. Circulation. 2010 Sep 21; 122(12):1176-82.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 20823386; PMCID: PMC3050056; DOI: 10.1161/CIRCULATIONAHA.109.931279;

Velagaleti RS, Gona P, Sundström J, Larson MG, Siwik D, Colucci WS, Benjamin EJ, Vasan RS. Relations of biomarkers of extracellular matrix remodeling to incident cardiovascular events and mortality. Arterioscler Thromb Vasc Biol. 2010 Nov; 30(11):2283-8.View Related Profiles.

Siwik, Deborah
Benjamin, Emelia
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Colucci, Wilson

PMID: 20798380; PMCID: PMC2959140; DOI: 10.1161/ATVBAHA.110.208462;

Upadhyay A, Larson MG, Guo CY, Vasan RS, Lipinska I, O'Donnell CJ, Kathiresan S, Meigs JB, Keaney JF, Rong J, Benjamin EJ, Fox CS. Inflammation, kidney function and albuminuria in the Framingham Offspring cohort. Nephrol Dial Transplant. 2011 Mar; 26(3):920-6.View Related Profiles.

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PMID: 20682604; PMCID: PMC3108344; DOI: 10.1093/ndt/gfq471;

Cheng S, Larson MG, Keyes MJ, McCabe EL, Newton-Cheh C, Levy D, Benjamin EJ, Vasan RS, Wang TJ. Relation of QRS width in healthy persons to risk of future permanent pacemaker implantation. Am J Cardiol. 2010 Sep 1; 106(5):668-72.View Related Profiles.

Benjamin, Emelia
Larson, Martin
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PMID: 20723643; PMCID: PMC3012354; DOI: 10.1016/j.amjcard.2010.04.021;

Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, de Bakker PI, Müller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dörr M, Navarro P, Fuchsberger C, Nolte IM, de Geus EJ, Estrada K, Hwang SJ, Bis JC, Rückert IM, Alonso A, Launer LJ, Hottenga JJ, Rivadeneira F, Noseworthy PA, Rice KM, Perz S, Arking DE, Spector TD, Kors JA, Aulchenko YS, Tarasov KV, Homuth G, Wild SH, Marroni F, Gieger C, Licht CM, Prineas RJ, Hofman A, Rotter JI, Hicks AA, Ernst F, Najjar SS, Wright AF, Peters A, Fox ER, Oostra BA, Kroemer HK, Couper D, Völzke H, Campbell H, Meitinger T, Uda M, Witteman JC, Psaty BM, Wichmann HE, Harris TB, Kääb S, Siscovick DS, Jamshidi Y, Uitterlinden AG, Folsom AR, Larson MG, Wilson JF, Penninx BW, Snieder H, Pramstaller PP, van Duijn CM, Lakatta EG, Felix SB, Gudnason V, Pfeufer A, Heckbert SR, Stricker BH, Boerwinkle E, O'Donnell CJ. Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet. 2010 Oct 1; 19(19):3885-94.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
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PMID: 20639392; PMCID: PMC3657480; DOI: 10.1093/hmg/ddq303;

Freedman JE, Larson MG, Tanriverdi K, O'Donnell CJ, Morin K, Hakanson AS, Vasan RS, Johnson AD, Iafrati MD, Benjamin EJ. Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study. Circulation. 2010 Jul 13; 122(2):119-29.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
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PMID: 20606121; PMCID: PMC2910759; DOI: 10.1161/CIRCULATIONAHA.109.928192;

Johnson AD, Yanek LR, Chen MH, Faraday N, Larson MG, Tofler G, Lin SJ, Kraja AT, Province MA, Yang Q, Becker DM, O'Donnell CJ, Becker LC. Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Nat Genet. 2010 Jul; 42(7):608-13.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Chen, Ming-Huei
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PMID: 20526338; PMCID: PMC3057573; DOI: 10.1038/ng.604;

Chen MH, Larson MG, Hsu YH, Peloso GM, Guo CY, Fox CS, Atwood LD, Yang Q. A three-stage approach for genome-wide association studies with family data for quantitative traits. BMC Genet. 2010; 11:40.View Related Profiles.

Peloso, Gina
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PMID: 20470424; PMCID: PMC2892427; DOI: 10.1186/1471-2156-11-40;

Lieb W, Gona P, Larson MG, Massaro JM, Lipinska I, Keaney JF, Rong J, Corey D, Hoffmann U, Fox CS, Vasan RS, Benjamin EJ, O'Donnell CJ, Kathiresan S. Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality. Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9):1849-54.View Related Profiles.

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PMID: 20448212; PMCID: PMC3039214; DOI: 10.1161/ATVBAHA.109.199661;

Levy D, Splansky GL, Strand NK, Atwood LD, Benjamin EJ, Blease S, Cupples LA, D'Agostino RB, Fox CS, Kelly-Hayes M, Koski G, Larson MG, Mutalik KM, Oberacker E, O'Donnell CJ, Sutherland P, Valentino M, Vasan RS, Wolf PA, Murabito JM. Consent for genetic research in the Framingham Heart Study. Am J Med Genet A. 2010 May; 152A(5):1250-6.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Murabito, Joanne
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Kelly-Hayes, Margaret
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Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 20425830; PMCID: PMC2923558; DOI: 10.1002/ajmg.a.33377;

Lieb W, Zachariah JP, Xanthakis V, Safa R, Chen MH, Sullivan LM, Larson MG, Smith HM, Yang Q, Mitchell GF, Vita JA, Sawyer DB, Vasan RS. Clinical and genetic correlates of circulating angiopoietin-2 and soluble Tie-2 in the community. Circ Cardiovasc Genet. 2010 Jun; 3(3):300-6.View Related Profiles.

Vita, Joseph
Sullivan, Lisa
Larson, Martin
Chen, Ming-Huei
Yang, Qiong
Xanthakis, Vanessa
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PMID: 20348331; PMCID: PMC2892960; DOI: 10.1161/CIRCGENETICS.109.914556;

Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Mälarstig A, Wiggins KL, Van Duijn CM, McArdle WL, Pankow JS, Johnson AD, Silveira A, McKnight B, Uitterlinden AG, Aleksic N, Meigs JB, Peters A, Koenig W, Cushman M, Kathiresan S, Rotter JI, Bovill EG, Hofman A, Boerwinkle E, Tofler GH, Peden JF, Psaty BM, Leebeek F, Folsom AR, Larson MG, Spector TD, Wright AF, Wilson JF, Hamsten A, Lumley T, Witteman JC, Tang W, O'Donnell CJ. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010 Mar 30; 121(12):1382-92.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Chen, Ming-Huei
Yang, Qiong

PMID: 20231535; PMCID: PMC2861278; DOI: 10.1161/CIRCULATIONAHA.109.869156;

Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF, Rice K, Lip GY, Vasan RS, Glazer NL, Larson MG, Uitterlinden AG, Yamamoto J, Durda P, Haritunians T, Psaty BM, Boerwinkle E, Hofman A, Koenig W, Jenny NS, Witteman JC, Ballantyne C, Benjamin EJ. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet. 2010 May 1; 19(9):1863-72.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Larson, Martin
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PMID: 20167578; PMCID: PMC2850624; DOI: 10.1093/hmg/ddq061;

McManus DD, Xanthakis V, Sullivan LM, Zachariah J, Aragam J, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left atrial diameter over the adult life course: Clinical correlates in the community. Circulation. 2010 Feb 9; 121(5):667-74.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Larson, Martin
Xanthakis, Vanessa
Ramachandran, Vasan

PMID: 20100973; PMCID: PMC2823068; DOI: 10.1161/CIRCULATIONAHA.109.885806;

Mitchell GF, Hwang SJ, Vasan RS, Larson MG, Pencina MJ, Hamburg NM, Vita JA, Levy D, Benjamin EJ. Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation. 2010 Feb 2; 121(4):505-11.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Pencina, Michael
Hamburg, Naomi
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 20083680; PMCID: PMC2836717; DOI: 10.1161/CIRCULATIONAHA.109.886655;

Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb; 42(2):153-9.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Lunetta, Kathryn
Larson, Martin
Ramachandran, Vasan

PMID: 20062060; PMCID: PMC2850197; DOI: 10.1038/ng.517;

Schnabel RB, Larson MG, Yamamoto JF, Sullivan LM, Pencina MJ, Meigs JB, Tofler GH, Selhub J, Jacques PF, Wolf PA, Magnani JW, Ellinor PT, Wang TJ, Levy D, Vasan RS, Benjamin EJ. Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation. 2010 Jan 19; 121(2):200-7.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Sullivan, Lisa
Larson, Martin
Pencina, Michael
Wolf, Philip
Ramachandran, Vasan

PMID: 20048208; PMCID: PMC3224826; DOI: 10.1161/CIRCULATIONAHA.109.882241;

Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF, Gieger C, Tilley C, Yamamoto JF, Khuseyinova N, Heiss G, Doyle M, Blankenberg S, Herder C, Walston JD, Zhu Y, Vasan RS, Klopp N, Boerwinkle E, Larson MG, Psaty BM, Peters A, Ballantyne CM, Witteman JC, Hoogeveen RC, Benjamin EJ, Koenig W, Tracy RP. Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood. 2010 Jul 1; 115(26):5289-99.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Larson, Martin
Ramachandran, Vasan

PMID: 20040767; PMCID: PMC2902130; DOI: 10.1182/blood-2009-05-221382;

Köttgen A, Hwang SJ, Larson MG, Van Eyk JE, Fu Q, Benjamin EJ, Dehghan A, Glazer NL, Kao WH, Harris TB, Gudnason V, Shlipak MG, Yang Q, Coresh J, Levy D, Fox CS. Uromodulin levels associate with a common UMOD variant and risk for incident CKD. J Am Soc Nephrol. 2010 Feb; 21(2):337-44.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Glazer, Nicole
Yang, Qiong
Hwang, Shih-Jen

PMID: 19959715; PMCID: PMC2834540; DOI: 10.1681/ASN.2009070725;

Chami HA, Keyes MJ, Vita JA, Mitchell GF, Larson MG, Fan S, Vasan RS, O'Connor GT, Benjamin EJ, Gottlieb DJ. Brachial artery diameter, blood flow and flow-mediated dilation in sleep-disordered breathing. Vasc Med. 2009 Nov; 14(4):351-60.View Related Profiles.

Gottlieb, Daniel
Benjamin, Emelia
O'Connor, George
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 19808720; PMCID: PMC2956304; DOI: 10.1177/1358863X09105132;

Tadros TM, Massaro JM, Rosito GA, Hoffmann U, Vasan RS, Larson MG, Keaney JF, Lipinska I, Meigs JB, Kathiresan S, O'Donnell CJ, Fox CS, Benjamin EJ. Pericardial fat volume correlates with inflammatory markers: the Framingham Heart Study. Obesity (Silver Spring). 2010 May; 18(5):1039-45.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Massaro, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 19875999; PMCID: PMC3014610; DOI: 10.1038/oby.2009.343;

Cheng S, Massaro JM, Fox CS, Larson MG, Keyes MJ, McCabe EL, Robins SJ, O'Donnell CJ, Hoffmann U, Jacques PF, Booth SL, Vasan RS, Wolf M, Wang TJ. Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. Diabetes. 2010 Jan; 59(1):242-8.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
Larson, Martin
Robins, Sander
Ramachandran, Vasan

PMID: 19833894; PMCID: PMC2797928; DOI: 10.2337/db09-1011;

Upadhyay A, Hwang SJ, Mitchell GF, Vasan RS, Vita JA, Stantchev PI, Meigs JB, Larson MG, Levy D, Benjamin EJ, Fox CS. Arterial stiffness in mild-to-moderate CKD. J Am Soc Nephrol. 2009 Sep; 20(9):2044-53.View Related Profiles.

Upadhyay, Ashish
Levy, Daniel
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 19608701; PMCID: PMC2736768; DOI: 10.1681/ASN.2009010074;

Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N, Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug; 41(8):879-81.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Larson, Martin
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19597492; PMCID: PMC2761746; DOI: 10.1038/ng.416;

Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009 Jul 8; 302(2):168-78.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Aragam, Jayashri
Larson, Martin
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PMID: 19584346; PMCID: PMC2975567; DOI: 10.1001/jama.2009.978-a;

Govindaraju DR, Larson MG, Yin X, Benjamin EJ, Rao MB, Vasan RS. Association between SNP heterozygosity and quantitative traits in the Framingham Heart Study. Ann Hum Genet. 2009 Jul; 73(Pt 4):465-73.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 19523151; PMCID: PMC3760672; DOI: 10.1111/j.1469-1809.2009.00514.x;

Cheng S, Keyes MJ, Larson MG, McCabe EL, Newton-Cheh C, Levy D, Benjamin EJ, Vasan RS, Wang TJ. Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block. JAMA. 2009 Jun 24; 301(24):2571-7.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19549974; PMCID: PMC2765917; DOI: 10.1001/jama.2009.888;

Pencina MJ, D'Agostino RB, Larson MG, Massaro JM, Vasan RS. Predicting the 30-year risk of cardiovascular disease: the framingham heart study. Circulation. 2009 Jun 23; 119(24):3078-84.View Related Profiles.

Massaro, Joseph
Larson, Martin
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Ramachandran, Vasan

PMID: 19506114; PMCID: PMC2748236; DOI: 10.1161/CIRCULATIONAHA.108.816694;

Lieb W, Xanthakis V, Sullivan LM, Aragam J, Pencina MJ, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left ventricular mass over the adult life course: clinical correlates of short- and long-term change in the framingham offspring study. Circulation. 2009 Jun 23; 119(24):3085-92.View Related Profiles.

Benjamin, Emelia
Aragam, Jayashri
Sullivan, Lisa
Larson, Martin
Pencina, Michael
Xanthakis, Vanessa
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PMID: 19506113; PMCID: PMC2761217; DOI: 10.1161/CIRCULATIONAHA.108.824243;

Lee DS, Gona P, Vasan RS, Larson MG, Benjamin EJ, Wang TJ, Tu JV, Levy D. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national heart, lung, and blood institute. Circulation. 2009 Jun 23; 119(24):3070-7.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19506115; PMCID: PMC2775498; DOI: 10.1161/CIRCULATIONAHA.108.815944;

Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 Jun; 41(6):677-87.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Glazer, Nicole
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 19430479; PMCID: PMC2998712; DOI: 10.1038/ng.384;

Schnabel RB, Larson MG, Yamamoto JF, Kathiresan S, Rong J, Levy D, Keaney JF, Wang TJ, Vasan RS, Benjamin EJ. Relation of multiple inflammatory biomarkers to incident atrial fibrillation. Am J Cardiol. 2009 Jul 1; 104(1):92-6.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 19576326; PMCID: PMC2802058; DOI: 10.1016/j.amjcard.2009.02.053;

Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, van Duijn CM, Kathiresan S, Illig T, Aulchenko YS, Volcik KA, Johnson AD, Uitterlinden AG, Tofler GH, Gieger C, Psaty BM, Couper DJ, Boerwinkle E, Koenig W, O'Donnell CJ, Witteman JC, Strachan DP, Smith NL, Folsom AR. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet. 2009 Apr; 2(2):125-33.View Related Profiles.

O'Donnell, Christopher
Massaro, Joseph
Larson, Martin
Chen, Ming-Huei
Yang, Qiong

PMID: 20031576; PMCID: PMC2764985; DOI: 10.1161/CIRCGENETICS.108.825224;

Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, Keaney JF, Vasan RS, Benjamin EJ. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circ Cardiovasc Genet. 2009 Jun; 2(3):229-37.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Chen, Ming-Huei
Ramachandran, Vasan

PMID: 20031590; PMCID: PMC2897047; DOI: 10.1161/CIRCGENETICS.108.804245;

Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ, Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009 Apr; 41(4):399-406.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Yin, Xiaoyan

PMID: 19305408; PMCID: PMC2701449; DOI: 10.1038/ng.364;

Fox CS, Gona P, Hoffmann U, Porter SA, Salton CJ, Massaro JM, Levy D, Larson MG, D'Agostino RB, O'Donnell CJ, Manning WJ. Pericardial fat, intrathoracic fat, and measures of left ventricular structure and function: the Framingham Heart Study. Circulation. 2009 Mar 31; 119(12):1586-91.View Related Profiles.

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PMID: 19289634; PMCID: PMC2727456; DOI: 10.1161/CIRCULATIONAHA.108.828970;

Parikh NI, Keyes MJ, Larson MG, Pou KM, Hamburg NM, Vita JA, O'Donnell CJ, Vasan RS, Mitchell GF, Hoffmann U, Fox CS, Benjamin EJ. Visceral and subcutaneous adiposity and brachial artery vasodilator function. Obesity (Silver Spring). 2009 Nov; 17(11):2054-9.View Related Profiles.

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PMID: 19282819; PMCID: PMC3086764; DOI: 10.1038/oby.2009.60;

Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study. Circulation. 2009 Mar 10; 119(9):1203-10.View Related Profiles.

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PMID: 19237656; PMCID: PMC2725400; DOI: 10.1161/CIRCULATIONAHA.108.825364;

Lieb W, Safa R, Benjamin EJ, Xanthakis V, Yin X, Sullivan LM, Larson MG, Smith HM, Vita JA, Mitchell GF, Sawyer DB, Vasan RS. Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. Eur Heart J. 2009 May; 30(9):1121-7.View Related Profiles.

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PMID: 19223316; PMCID: PMC2721714; DOI: 10.1093/eurheartj/ehp007;

Newton-Cheh C, Larson MG, Vasan RS, Levy D, Bloch KD, Surti A, Guiducci C, Kathiresan S, Benjamin EJ, Struck J, Morgenthaler NG, Bergmann A, Blankenberg S, Kee F, Nilsson P, Yin X, Peltonen L, Vartiainen E, Salomaa V, Hirschhorn JN, Melander O, Wang TJ. Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure. Nat Genet. 2009 Mar; 41(3):348-53.View Related Profiles.

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PMID: 19219041; PMCID: PMC2664511; DOI: 10.1038/ng.328;

Kääb S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF, Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J, Perz S, Lunetta KL, Larson MG, Levy D, MacRae CA, Ruskin JN, Wacker A, Schömig A, Wichmann HE, Steinbeck G, Meitinger T, Uitterlinden AG, Witteman JC, Roden DM, Benjamin EJ, Ellinor PT. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J. 2009 Apr; 30(7):813-9.View Related Profiles.

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PMID: 19141561; PMCID: PMC2663727; DOI: 10.1093/eurheartj/ehn578;

Chen TH, Gona P, Sutherland PA, Benjamin EJ, Wilson PW, Larson MG, Vasan RS, Robins SJ. Long-term C-reactive protein variability and prediction of metabolic risk. Am J Med. 2009 Jan; 122(1):53-61.View Related Profiles.

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PMID: 19114172; PMCID: PMC2654380; DOI: 10.1016/j.amjmed.2008.08.023;

Franklin SS, Lopez VA, Wong ND, Mitchell GF, Larson MG, Vasan RS, Levy D. Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study. Circulation. 2009 Jan 20; 119(2):243-50.View Related Profiles.

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PMID: 19118251; PMCID: PMC3042701; DOI: 10.1161/CIRCULATIONAHA.108.797936;

Lieb W, Larson MG, Benjamin EJ, Yin X, Tofler GH, Selhub J, Jacques PF, Wang TJ, Vita JA, Levy D, Vasan RS, Mitchell GF. Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation. 2009 Jan 6; 119(1):37-43.View Related Profiles.

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PMID: 19103986; PMCID: PMC2722113; DOI: 10.1161/CIRCULATIONAHA.108.816108;

Velagaleti RS, Gona P, Levy D, Aragam J, Larson MG, Tofler GH, Lieb W, Wang TJ, Benjamin EJ, Vasan RS. Relations of biomarkers representing distinct biological pathways to left ventricular geometry. Circulation. 2008 Nov 25; 118(22):2252-8, 5p following 2258.View Related Profiles.

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PMID: 19001021; PMCID: PMC2747641; DOI: 10.1161/CIRCULATIONAHA.108.817411;

Schnabel R, Dupuis J, Larson MG, Lunetta KL, Robins SJ, Zhu Y, Rong J, Yin X, Stirnadel HA, Nelson JJ, Wilson PW, Keaney JF, Vasan RS, Benjamin EJ. Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study. Atherosclerosis. 2009 Jun; 204(2):601-7.View Related Profiles.

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PMID: 19135199; PMCID: PMC2893025; DOI: 10.1016/j.atherosclerosis.2008.10.030;

Keaney JF, Lipinska I, Larson MG, Dupuis J, Freedman JE, Hamburg NM, Massaro JM, Rong J, Sutherland P, Vita JA, Vasan RS, Benjamin EJ. Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study. Am Heart J. 2008 Nov; 156(5):1003-1009.e1.View Related Profiles.

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PMID: 19061720; PMCID: PMC2613323; DOI: 10.1016/j.ahj.2008.06.041;

Young JA, Hwang SJ, Sarnak MJ, Hoffmann U, Massaro JM, Levy D, Benjamin EJ, Larson MG, Vasan RS, O'Donnell CJ, Fox CS. Association of visceral and subcutaneous adiposity with kidney function. Clin J Am Soc Nephrol. 2008 Nov; 3(6):1786-91.View Related Profiles.

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PMID: 18815239; PMCID: PMC2572280; DOI: 10.2215/CJN.02490508;

Parikh NI, Hwang SJ, Yang Q, Larson MG, Guo CY, Robins SJ, Sutherland P, Benjamin EJ, Levy D, Fox CS. Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study). Am J Cardiol. 2008 Nov 1; 102(9):1194-8.View Related Profiles.

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PMID: 18940290; PMCID: PMC2709776; DOI: 10.1016/j.amjcard.2008.06.039;

Ingelsson E, Gona P, Larson MG, Lloyd-Jones DM, Kannel WB, Vasan RS, Levy D. Altered blood pressure progression in the community and its relation to clinical events. Arch Intern Med. 2008 Jul 14; 168(13):1450-7.View Related Profiles.

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PMID: 18625926; PMCID: PMC3023922; DOI: 10.1001/archinte.168.13.1450;

Foster MC, Keyes MJ, Larson MG, Vita JA, Mitchell GF, Meigs JB, Vasan RS, Benjamin EJ, Fox CS. Relations of measures of endothelial function and kidney disease: the Framingham Heart Study. Am J Kidney Dis. 2008 Nov; 52(5):859-67.View Related Profiles.

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PMID: 18617305; PMCID: PMC2665728; DOI: 10.1053/j.ajkd.2008.04.027;

Lieb W, Pencina MJ, Wang TJ, Larson MG, Lanier KJ, Benjamin EJ, Levy D, Tofler GH, Meigs JB, Newton-Cheh C, Vasan RS. Association of parental hypertension with concentrations of select biomarkers in nonhypertensive offspring. Hypertension. 2008 Aug; 52(2):381-6.View Related Profiles.

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PMID: 18574071; PMCID: PMC2574605; DOI: 10.1161/HYPERTENSIONAHA.108.113589;

Kottgen A, Kao WH, Hwang SJ, Boerwinkle E, Yang Q, Levy D, Benjamin EJ, Larson MG, Astor BC, Coresh J, Fox CS. Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies. BMC Med Genet. 2008; 9:49.View Related Profiles.

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PMID: 18522750; PMCID: PMC2430944; DOI: 10.1186/1471-2350-9-49;

Parikh NI, Hwang SJ, Larson MG, Hoffmann U, Levy D, Meigs JB, O'Donnell CJ, Fox CS. Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study). Am J Cardiol. 2008 Aug 15; 102(4):440-3.View Related Profiles.

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PMID: 18678302; PMCID: PMC2709777; DOI: 10.1016/j.amjcard.2008.04.007;

Ingelsson E, Larson MG, Yin X, Wang TJ, Meigs JB, Lipinska I, Benjamin EJ, Keaney JF, Vasan RS. Circulating ghrelin, leptin, and soluble leptin receptor concentrations and cardiometabolic risk factors in a community-based sample. J Clin Endocrinol Metab. 2008 Aug; 93(8):3149-57.View Related Profiles.

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PMID: 18492761; PMCID: PMC2515078; DOI: 10.1210/jc.2008-0207;

Parikh NI, Hwang SJ, Larson MG, Levy D, Fox CS. Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol. 2008 Jul 1; 102(1):47-53.View Related Profiles.

Larson, Martin
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PMID: 18572034; PMCID: PMC2517213; DOI: 10.1016/j.amjcard.2008.02.095;

Hamburg NM, Keyes MJ, Larson MG, Vasan RS, Schnabel R, Pryde MM, Mitchell GF, Sheffy J, Vita JA, Benjamin EJ. Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation. 2008 May 13; 117(19):2467-74.View Related Profiles.

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PMID: 18458169; PMCID: PMC2734141; DOI: 10.1161/CIRCULATIONAHA.107.748574;

Foster MC, Hwang SJ, Larson MG, Lichtman JH, Parikh NI, Vasan RS, Levy D, Fox CS. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. Am J Kidney Dis. 2008 Jul; 52(1):39-48.View Related Profiles.

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PMID: 18440684; PMCID: PMC2531220; DOI: 10.1053/j.ajkd.2008.03.003;

Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF, Vasan RS, Mitchell GF, Benjamin EJ. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension. 2008 Jun; 51(6):1651-7.View Related Profiles.

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PMID: 18426996; PMCID: PMC2892983; DOI: 10.1161/HYPERTENSIONAHA.107.105668;

Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP. Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet. 2008 May; 40(5):592-9. PMID: 18391953; PMCID: PMC3766631; DOI: 10.1038/ng.118;

Verzilli C, Shah T, Casas JP, Chapman J, Sandhu M, Debenham SL, Boekholdt MS, Khaw KT, Wareham NJ, Judson R, Benjamin EJ, Kathiresan S, Larson MG, Rong J, Sofat R, Humphries SE, Smeeth L, Cavalleri G, Whittaker JC, Hingorani AD. Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet. 2008 Apr; 82(4):859-72.View Related Profiles.

Benjamin, Emelia
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PMID: 18394581; PMCID: PMC2665011; DOI: 10.1016/j.ajhg.2008.01.016;

Lewis GD, Gona P, Larson MG, Plehn JF, Benjamin EJ, O'Donnell CJ, Levy D, Vasan RS, Wang TJ. Exercise blood pressure and the risk of incident cardiovascular disease (from the Framingham Heart Study). Am J Cardiol. 2008 Jun 1; 101(11):1614-20.View Related Profiles.

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PMID: 18489939; PMCID: PMC2953798; DOI: 10.1016/j.amjcard.2008.01.046;

Levitzky YS, Guo CY, Rong J, Larson MG, Walter RE, Keaney JF, Sutherland PA, Vasan A, Lipinska I, Evans JC, Benjamin EJ. Relation of smoking status to a panel of inflammatory markers: the framingham offspring. Atherosclerosis. 2008 Nov; 201(1):217-24.View Related Profiles.

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PMID: 18289552; PMCID: PMC2783981; DOI: 10.1016/j.atherosclerosis.2007.12.058;

Maia AL, Hwang SJ, Levy D, Larson MG, Larsen PR, Fox CS. Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study. Hypertension. 2008 Apr; 51(4):e22-3.View Related Profiles.

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PMID: 18285610; PMCID: PMC3014057; DOI: 10.1161/HYPERTENSIONAHA.107.109454;

Larson MG. Analysis of variance. Circulation. 2008 Jan 1; 117(1):115-21. PMID: 18172051; DOI: 10.1161/CIRCULATIONAHA.107.654335;

Hamburg NM, Larson MG, Vita JA, Vasan RS, Keyes MJ, Widlansky ME, Fox CS, Mitchell GF, Levy D, Meigs JB, Benjamin EJ. Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease. Am J Cardiol. 2008 Jan 1; 101(1):82-8.View Related Profiles.

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PMID: 18157970; PMCID: PMC2214853; DOI: 10.1016/j.amjcard.2007.07.053;

Oyama N, Gona P, Salton CJ, Chuang ML, Jhaveri RR, Blease SJ, Manning AR, Lahiri M, Botnar RM, Levy D, Larson MG, O'Donnell CJ, Manning WJ. Differential impact of age, sex, and hypertension on aortic atherosclerosis: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2008 Jan; 28(1):155-9.View Related Profiles.

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PMID: 17991874

Lee DS, Larson MG, Lunetta KL, Dupuis J, Rong J, Keaney JF, Lipinska I, Baldwin CT, Vasan RS, Benjamin EJ. Clinical and genetic correlates of soluble P-selectin in the community. J Thromb Haemost. 2008 Jan; 6(1):20-31.View Related Profiles.

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PMID: 17944986

Walter RE, Wilk JB, Larson MG, Vasan RS, Keaney JF, Lipinska I, O'Connor GT, Benjamin EJ. Systemic inflammation and COPD: the Framingham Heart Study. Chest. 2008 Jan; 133(1):19-25.View Related Profiles.

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Yang Q, Kim SK, Sun F, Cui J, Larson MG, Vasan RS, Levy D, Schwartz F. Maternal influence on blood pressure suggests involvement of mitochondrial DNA in the pathogenesis of hypertension: the Framingham Heart Study. J Hypertens. 2007 Oct; 25(10):2067-73.View Related Profiles.

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Parikh NI, Gona P, Larson MG, Wang TJ, Newton-Cheh C, Levy D, Benjamin EJ, Kannel WB, Vasan RS. Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study. Eur Heart J. 2007 Nov; 28(21):2644-52.View Related Profiles.

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Benjamin EJ, Dupuis J, Larson MG, Lunetta KL, Booth SL, Govindaraju DR, Kathiresan S, Keaney JF, Keyes MJ, Lin JP, Meigs JB, Robins SJ, Rong J, Schnabel R, Vita JA, Wang TJ, Wilson PW, Wolf PA, Vasan RS. Genome-wide association with select biomarker traits in the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S11.View Related Profiles.

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PMID: 17903293; PMCID: PMC1995615; DOI: 10.1186/1471-2350-8-S1-S11;

Levy D, Larson MG, Benjamin EJ, Newton-Cheh C, Wang TJ, Hwang SJ, Vasan RS, Mitchell GF. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. BMC Med Genet. 2007; 8 Suppl 1:S3.View Related Profiles.

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PMID: 17903302; PMCID: PMC1995621; DOI: 10.1186/1471-2350-8-S1-S3;

Larson MG, Atwood LD, Benjamin EJ, Cupples LA, D'Agostino RB, Fox CS, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Murabito JM, Newton-Cheh C, O'Donnell CJ, Seshadri S, Vasan RS, Wang TJ, Wolf PA, Levy D. Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet. 2007; 8 Suppl 1:S5.View Related Profiles.

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PMID: 17903304; PMCID: PMC1995607; DOI: 10.1186/1471-2350-8-S1-S5;

Vasan RS, Larson MG, Aragam J, Wang TJ, Mitchell GF, Kathiresan S, Newton-Cheh C, Vita JA, Keyes MJ, O'Donnell CJ, Levy D, Benjamin EJ. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S2.View Related Profiles.

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PMID: 17903301; PMCID: PMC1995617; DOI: 10.1186/1471-2350-8-S1-S2;

Newton-Cheh C, Guo CY, Wang TJ, O'donnell CJ, Levy D, Larson MG. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S7.View Related Profiles.

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PMID: 17903306; PMCID: PMC1995612; DOI: 10.1186/1471-2350-8-S1-S7;

Parikh NI, Hwang SJ, Larson MG, Cupples LA, Fox CS, Manders ES, Murabito JM, Massaro JM, Hoffmann U, O'Donnell CJ. Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts. Circulation. 2007 Sep 25; 116(13):1473-81.View Related Profiles.

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Newton-Cheh C, Guo CY, Larson MG, Musone SL, Surti A, Camargo AL, Drake JA, Benjamin EJ, Levy D, D'Agostino RB, Hirschhorn JN, O'donnell CJ. Common genetic variation in KCNH2 is associated with QT interval duration: the Framingham Heart Study. Circulation. 2007 Sep 4; 116(10):1128-36.View Related Profiles.

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Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, Keaney JF, Meigs JB, Lipinska I, Kathiresan S, Murabito JM, O'Donnell CJ, Benjamin EJ, Fox CS. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation. 2007 Sep 11; 116(11):1234-41.View Related Profiles.

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Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB, Wang TJ, Vasan RS. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation. 2007 Aug 28; 116(9):984-92.View Related Profiles.

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Wang TJ, Larson MG, Benjamin EJ, Siwik DA, Safa R, Guo CY, Corey D, Sundstrom J, Sawyer DB, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma procollagen type III amino-terminal peptide levels in the community. Am Heart J. 2007 Aug; 154(2):291-7.View Related Profiles.

Siwik, Deborah
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PMID: 17643579; PMCID: PMC3170820; DOI: 10.1016/j.ahj.2007.04.006;

Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS. Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes. Arch Intern Med. 2007 Jul 9; 167(13):1386-92.View Related Profiles.

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Meigs JB, Larson MG, Fox CS, Keaney JF, Vasan RS, Benjamin EJ. Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study. Diabetes Care. 2007 Oct; 30(10):2529-35.View Related Profiles.

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Widlansky ME, Vita JA, Keyes MJ, Larson MG, Hamburg NM, Levy D, Mitchell GF, Osypiuk EW, Vasan RS, Benjamin EJ. Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol. 2007 Aug 1; 100(3):518-23.View Related Profiles.

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PMID: 17659939; PMCID: PMC1994775; DOI: 10.1016/j.amjcard.2007.03.055;

Ingelsson E, Larson MG, Vasan RS, O'Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S. Heritability, linkage, and genetic associations of exercise treadmill test responses. Circulation. 2007 Jun 12; 115(23):2917-24.View Related Profiles.

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Levy D, Hwang SJ, Kayalar A, Benjamin EJ, Vasan RS, Parise H, Larson MG, Wang TJ, Selhub J, Jacques PF, Vita JA, Keyes MJ, Mitchell GF. Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study. Circulation. 2007 Jun 19; 115(24):3079-85.View Related Profiles.

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Mitchell GF, Guo CY, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study. Circulation. 2007 May 22; 115(20):2628-36.View Related Profiles.

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Thakore AH, Guo CY, Larson MG, Corey D, Wang TJ, Vasan RS, D'Agostino RB, Lipinska I, Keaney JF, Benjamin EJ, O'Donnell CJ. Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study). Am J Cardiol. 2007 Jun 1; 99(11):1598-602.View Related Profiles.

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Ramachandran, Vasan

PMID: 17531588

Mitchell GF, Guo CY, Kathiresan S, Vasan RS, Larson MG, Vita JA, Keyes MJ, Vyas M, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study. Hypertension. 2007 Jun; 49(6):1285-90.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 17404185

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C. Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study. Neurology. 2007 Mar 27; 68(13):1032-8.View Related Profiles.

Benjamin, Emelia
Massaro, Joseph
Larson, Martin
Wolf, Philip
Au, Rhoda
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17389308; PMCID: PMC2758770; DOI: 10.1212/01.wnl.0000257815.20548.df;

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D'Agostino RB, Fox CS, Larson MG, Murabito JM, O'Donnell CJ, Vasan RS, Wolf PA, Levy D. The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol. 2007 Jun 1; 165(11):1328-35.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Murabito, Joanne
Cupples, L
Larson, Martin
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17372189

Pencina MJ, Larson MG, D'Agostino RB. Choice of time scale and its effect on significance of predictors in longitudinal studies. Stat Med. 2007 Mar 15; 26(6):1343-59.View Related Profiles.

Larson, Martin
Pencina, Michael
D'Agostino, Ralph

PMID: 16955538

Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS. Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals. Circulation. 2007 Mar 20; 115(11):1345-53.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17339551

Mitchell GF, Vasan RS, Keyes MJ, Parise H, Wang TJ, Larson MG, D'Agostino RB, Kannel WB, Levy D, Benjamin EJ. Pulse pressure and risk of new-onset atrial fibrillation. JAMA. 2007 Feb 21; 297(7):709-15.View Related Profiles.

Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17312290

Newton-Cheh C, Guo CY, Gona P, Larson MG, Benjamin EJ, Wang TJ, Kathiresan S, O'Donnell CJ, Musone SL, Camargo AL, Drake JA, Levy D, Hirschhorn JN, Vasan RS. Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample. Hypertension. 2007 Apr; 49(4):846-56.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17296870

Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney JF, Vasan RS. Clinical correlates of circulating visfatin levels in a community-based sample. Diabetes Care. 2007 May; 30(5):1278-80.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 17261750

Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS. Multiple biomarkers and the risk of incident hypertension. Hypertension. 2007 Mar; 49(3):432-8.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Robins, Sander
Ramachandran, Vasan

PMID: 17242302

Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Liu, Chunyu
Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Larson, Martin
Heard-Costa, Nancy
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Demissie, Serkalem
Hwang, Shih-Jen
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17903291; PMCID: PMC1995613; DOI: 10.1186/1471-2350-8-S1-S1;

Wang TJ, Gona P, Larson MG, Tofler GH, Levy D, Newton-Cheh C, Jacques PF, Rifai N, Selhub J, Robins SJ, Benjamin EJ, D'Agostino RB, Vasan RS. Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med. 2006 Dec 21; 355(25):2631-9.View Related Profiles.

Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Robins, Sander
Ramachandran, Vasan

PMID: 17182988

Kathiresan S, Larson MG, Keyes MJ, Polak JF, Wolf PA, D'Agostino RB, Jaffer FA, Clouse ME, Levy D, Manning WJ, O'Donnell CJ. Assessment by cardiovascular magnetic resonance, electron beam computed tomography, and carotid ultrasonography of the distribution of subclinical atherosclerosis across Framingham risk strata. Am J Cardiol. 2007 Feb 1; 99(3):310-4.View Related Profiles.

O'Donnell, Christopher
Polak, Joseph
Larson, Martin
Wolf, Philip
D'Agostino, Ralph

PMID: 17261388

Arnlöv J, Evans JC, Benjamin EJ, Larson MG, Levy D, Sutherland P, Siwik DA, Wang TJ, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma osteopontin in the community: the Framingham Heart Study. Heart. 2006 Oct; 92(10):1514-5.View Related Profiles.

Siwik, Deborah
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan
Colucci, Wilson

PMID: 16973806; PMCID: PMC1861062; DOI: 10.1136/hrt.2005.081406;

Patwardhan AA, Larson MG, Levy D, Benjamin EJ, Leip EP, Keyes MJ, Wang TJ, Gottlieb DJ, Vasan RS. Obstructive sleep apnea and plasma natriuretic peptide levels in a community-based sample. Sleep. 2006 Oct; 29(10):1301-6.View Related Profiles.

Patwardhan, Anjali
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 17068983

Parikh NI, Hwang SJ, Larson MG, Meigs JB, Levy D, Fox CS. Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control. Arch Intern Med. 2006 Sep 25; 166(17):1884-91.View Related Profiles.

Larson, Martin
Hwang, Shih-Jen

PMID: 17000946

O'Donnell CJ, Shea MK, Price PA, Gagnon DR, Wilson PW, Larson MG, Kiel DP, Hoffmann U, Ferencik M, Clouse ME, Williamson MK, Cupples LA, Dawson-Hughes B, Booth SL. Matrix Gla protein is associated with risk factors for atherosclerosis but not with coronary artery calcification. Arterioscler Thromb Vasc Biol. 2006 Dec; 26(12):2769-74.View Related Profiles.

O'Donnell, Christopher
Gagnon, David
Cupples, L
Larson, Martin

PMID: 16973975; PMCID: PMC2562549; DOI: 10.1161/01.ATV.0000245793.83158.06;

Demissie S, Levy D, Benjamin EJ, Cupples LA, Gardner JP, Herbert A, Kimura M, Larson MG, Meigs JB, Keaney JF, Aviv A. Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell. 2006 Aug; 5(4):325-30.View Related Profiles.

Herbert, Alan
Levy, Daniel
Benjamin, Emelia
Cupples, L
Larson, Martin
Demissie, Serkalem

PMID: 16913878

Lee DS, Pencina MJ, Benjamin EJ, Wang TJ, Levy D, O'Donnell CJ, Nam BH, Larson MG, D'Agostino RB, Vasan RS. Association of parental heart failure with risk of heart failure in offspring. N Engl J Med. 2006 Jul 13; 355(2):138-47.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16837677

Larson MG. Descriptive statistics and graphical displays. Circulation. 2006 Jul 4; 114(1):76-81. PMID: 16818830

Morita H, Larson MG, Barr SC, Vasan RS, O'Donnell CJ, Hirschhorn JN, Levy D, Corey D, Seidman CE, Seidman JG, Benjamin EJ. Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study. Circulation. 2006 Jun 13; 113(23):2697-705.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16754800

Fox CS, Larson MG, Hwang SJ, Leip EP, Rifai N, Levy D, Benjamin EJ, Murabito JM, Meigs JB, Vasan RS. Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample. Kidney Int. 2006 Jun; 69(11):2064-9.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Larson, Martin
Ramachandran, Vasan

PMID: 16572107

Levy D, DePalma SR, Benjamin EJ, O'Donnell CJ, Parise H, Hirschhorn JN, Vasan RS, Izumo S, Larson MG. Phenotype-genotype association grid: a convenient method for summarizing multiple association analyses. BMC Genet. 2006; 7:30.View Related Profiles.

O'Donnell, Christopher
Levy, Daniel
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16716207; PMCID: PMC1526453; DOI: 10.1186/1471-2156-7-30;

Meigs JB, Dupuis J, Liu C, O'Donnell CJ, Fox CS, Kathiresan S, Gabriel SB, Larson MG, Yang Q, Herbert AG, Wilson PW, Feng D, Tofler GH, Cupples LA. PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample. Obesity (Silver Spring). 2006 May; 14(5):753-8.View Related Profiles.

Herbert, Alan
O'Donnell, Christopher
Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin

PMID: 16855181

Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O'Donnell CJ, Hirschhorn JN, Kääb S, Spooner PM, Meitinger T, Chakravarti A. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet. 2006 Jun; 38(6):644-51.View Related Profiles.

O'Donnell, Christopher
Larson, Martin

PMID: 16648850

Kathiresan S, Yang Q, Larson MG, Camargo AL, Tofler GH, Hirschhorn JN, Gabriel SB, O'Donnell CJ. Common genetic variation in five thrombosis genes and relations to plasma hemostatic protein level and cardiovascular disease risk. Arterioscler Thromb Vasc Biol. 2006 Jun; 26(6):1405-12.View Related Profiles.

O'Donnell, Christopher
Larson, Martin

PMID: 16614319

Dhingra R, Pencina MJ, Wang TJ, Nam BH, Benjamin EJ, Levy D, Larson MG, Kannel WB, D'Agostino RB, Vasan RS. Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study. Hypertension. 2006 May; 47(5):861-7.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Pencina, Michael
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16585411

Fox CS, Guo CY, Larson MG, Vasan RS, Parise H, O'Donnell CJ, D'Agostino RB, Keaney JF, Benjamin EJ. Relations of inflammation and novel risk factors to valvular calcification. Am J Cardiol. 2006 May 15; 97(10):1502-5.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16679093

Kathiresan S, Larson MG, Vasan RS, Guo CY, Gona P, Keaney JF, Wilson PW, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation. 2006 Mar 21; 113(11):1415-23.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16534007

Kathiresan S, Gona P, Larson MG, Vita JA, Mitchell GF, Tofler GH, Levy D, Newton-Cheh C, Wang TJ, Benjamin EJ, Vasan RS. Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function. Circulation. 2006 Feb 21; 113(7):938-45.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 16476848

Lloyd-Jones DM, Leip EP, Larson MG, D'Agostino RB, Beiser A, Wilson PW, Wolf PA, Levy D. Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age. Circulation. 2006 Feb 14; 113(6):791-8.View Related Profiles.

Beiser, Alexa
Larson, Martin
Wolf, Philip
D'Agostino, Ralph

PMID: 16461820

Dhingra R, Larson MG, Benjamin EJ, Lipinska I, Gona P, Corey D, Keaney JF, Vasan RS. Cross-sectional correlates of serum heat shock protein 70 in the community. Am J Hypertens. 2006 Feb; 19(2):227-31; discussion 232-3.View Related Profiles.

Benjamin, Emelia
Larson, Martin
Ramachandran, Vasan

PMID: 16448898

Loucks EB, Sullivan LM, D'Agostino RB, Larson MG, Berkman LF, Benjamin EJ. Social networks and inflammatory markers in the Framingham Heart Study. J Biosoc Sci. 2006 Nov; 38(6):835-42.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
Larson, Martin
D'Agostino, Ralph

PMID: 16441967

Loucks EB, Sullivan LM, Hayes LJ, D'Agostino RB, Larson MG, Vasan RS, Benjamin EJ, Berkman LF. Association of educational level with inflammatory markers in the Framingham Offspring Study. Am J Epidemiol. 2006 Apr 1; 163(7):622-8.View Related Profiles.

Benjamin, Emelia
Sullivan, Lisa
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16421236

Fox CS, Larson MG, Vasan RS, Guo CY, Parise H, Levy D, Leip EP, O'donnell CJ, D'Agostino RB, Benjamin EJ. Cross-sectional association of kidney function with valvular and annular calcification: the Framingham heart study. J Am Soc Nephrol. 2006 Feb; 17(2):521-7.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Larson, Martin
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 16382018

Mitchell GF, Vita JA, Larson MG, Parise H, Keyes MJ, Warner E, Vasan RS, Levy D, Benjamin EJ. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation. 2005 Dec 13; 112(24):3722-8.View Related Profiles.

Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 16330686

Peter I, Shearman AM, Zucker DR, Schmid CH, Demissie S, Cupples LA, Larson MG, Vasan RS, D'Agostino RB, Karas RH, Mendelsohn ME, Housman DE, Levy D. Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study. J Hypertens. 2005 Dec; 23(12):2193-200.View Related Profiles.

Cupples, L
Larson, Martin
D'Agostino, Ralph
Demissie, Serkalem
Ramachandran, Vasan

PMID: 16269961

Fox CS, Larson MG, Leip EP, Meigs JB, Wilson PW, Levy D. Glycemic status and development of kidney disease: the Framingham Heart Study. Diabetes Care. 2005 Oct; 28(10):2436-40. PMID: 16186276

Kathiresan S, Gabriel SB, Yang Q, Lochner AL, Larson MG, Levy D, Tofler GH, Hirschhorn JN, O'Donnell CJ. Comprehensive survey of common genetic variation at the plasminogen activator inhibitor-1 locus and relations to circulating plasminogen activator inhibitor-1 levels. Circulation. 2005 Sep 20; 112(12):1728-35.View Related Profiles.

O'Donnell, Christopher
Larson, Martin
Yang, Qiong

PMID: 16172282

Kathiresan S, Larson MG, Vasan RS, Guo CY, Vita JA, Mitchell GF, Keyes MJ, Newton-Cheh C, Musone SL, Lochner AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ. Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community. Circulation. 2005 Sep 6; 112(10):1419-27.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Ramachandran, Vasan

PMID: 16129794

McDermott DH, Yang Q, Kathiresan S, Cupples LA, Massaro JM, Keaney JF, Larson MG, Vasan RS, Hirschhorn JN, O'Donnell CJ, Murphy PM, Benjamin EJ. CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the Framingham Heart Study. Circulation. 2005 Aug 23; 112(8):1113-20.View Related Profiles.

O'Donnell, Christopher
Benjamin, Emelia
Massaro, Joseph
Cupples, L
Larson, Martin
Yang, Qiong
Ramachandran, Vasan

PMID: 16116069

Mitchell GF, DeStefano AL, Larson MG, Benjamin EJ, Chen MH, Vasan RS, Vita JA, Levy D. Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study. Circulation. 2005 Jul 12; 112(2):194-9.View Related Profiles.

DeStefano, Anita
Benjamin, Emelia
Vita, Joseph
Larson, Martin
Chen, Ming-Huei
Ramachandran, Vasan

PMID: 15998672