Laurence H. Beck Jr, MD, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Medicine
Nephrology

MD, Harvard Medical School
PhD, Harvard University



Laurence H. Beck, Jr., MD, PhD, completed his Internal Medicine residency and Nephrology fellowship at Boston Medical Center. He joined the Renal Section in 2006, and continues to conduct basic science research in the laboratory of Dr. David Salant on the pathogenesis of membranous nephropathy. His clinical roles include a weekly clinic and attending time on the consult and dialysis/transplant services. He also has expertise in immune-mediated glomerular disease.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences





Investigating the functional capacity of autoantibodies in p
09/20/2021 - 06/30/2024 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
1R01DK126978-01A1

A PHASE 2, 12-WEEK, ADAPTIVE, OPEN LABEL, SEQUENTIAL COHORT TRIAL TO EVALUATE THE EFFICACY, …
10/17/2019 - 10/16/2022 (PI)
Pfizer, Inc

Redefining Membranous Nephropathy by Autoantibody-specific Subclassification
01/22/2013 - 12/31/2018 (PI)
NIH-NIDDK
1R01DK097053-03

Redifining Membranous Nephropathy by Autoantibody-specific Subclassification
01/22/2013 - 12/31/2018 (PI)
NIH-NIDDK
5R01DK097053-05

Investigation of Anti-PLA2R-Associated Membranous Nephropathy at the Molecular Level
09/01/2011 - 06/30/2013 (PI)
The Halpin Foundation

Detection of anti-phospholipase A2 receptor autoantibodies in idiopathic membranous nephropathy
07/01/2009 - 06/30/2013 (PI)
Amer Soc Nephrology

Identification of the endogenous antigen and development of an ELISA for the detection of autoantibo
07/01/2007 - 06/30/2013 (PI)
AMGEN, INC

Identification of the Endogenous Antigen and Development of an ELISA for the Detection of Autoantibo
07/01/2007 - 06/30/2009 (PI)
The Halpin Foundation


Title

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Manral P, Caza TN, Storey AJ, Beck LH, Borza DB. The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy. Front Immunol. 2022; 13:952235. PMID: 35874690; PMCID: PMC9301376; DOI: 10.3389/fimmu.2022.952235;
     
  2. Sealfon R, Mariani L, Avila-Casado C, Nair V, Menon R, Funk J, Wong A, Lerner G, Hayashi N, Troyanskaya O, Kretzler M, Beck LH. Molecular Characterization of Membranous Nephropathy. J Am Soc Nephrol. 2022 Jun; 33(6):1208-1221. PMID: 35477557; PMCID: PMC9161788; DOI: 10.1681/ASN.2021060784;
     
  3. Kamel MH, Jaberi A, Gordon CE, Beck LH, Francis J. The Complement System in the Modern Era of Kidney Transplantation: Mechanisms of Injury and Targeted Therapies. Semin Nephrol. 2022 Jan; 42(1):14-28.View Related Profiles. PMID: 35618392
     
  4. Caza TN, Al-Rabadi LF, Beck LH. How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy. Front Immunol. 2021; 12:800242. PMID: 34899763; PMCID: PMC8662735; DOI: 10.3389/fimmu.2021.800242;
     
  5. Watts AJB, Keller KH, Lerner G, Rosales I, Collins AB, Sekulic M, Waikar SS, Chandraker A, Riella LV, Alexander MP, Troost JP, Chen J, Fermin D, Yee JL, Sampson MG, Beck LH, Henderson JM, Greka A, Rennke HG, Weins A. Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology. J Am Soc Nephrol. 2022 01; 33(1):238-252.View Related Profiles. PMID: 34732507; PMCID: PMC8763186; DOI: 10.1681/ASN.2021060794;
     
  6. Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J. Membranous nephropathy. Nat Rev Dis Primers. 2021 09 30; 7(1):69. PMID: 34593809
     
  7. Bomback AS, Appel GB, Gipson DS, Hladunewich MA, Lafayette R, Nester CM, Parikh SV, Smith RJH, Trachtman H, Heeger PS, Ram S, Rovin BH, Ali S, Arceneaux N, Ashoor I, Bailey-Wickins L, Barratt J, Beck L, Cattran DC, Cravedi P, Erkan E, Fervenza F, Frazer-Abel AA, Fremeaux-Bacchi V, Fuller L, Gbadegesin R, Hogan JJ, Kiryluk K, le Quintrec-Donnette M, Licht C, Mahan JD, Pickering MC, Quigg R, Rheault M, Ronco P, Sarwal MM, Sethna C, Spino C, Stegall M, Vivarelli M, Feldman DL, Thurman JM. Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. Am J Kidney Dis. 2022 04; 79(4):570-581. PMID: 34571062
     
  8. Nasr SH, Leung N, Said SM, Alkhateeb HB, Madden BJ, Charlesworth MC, Beck LH, Larsen CP, Sethi S. Membranous Nephropathy With Extensive Tubular Basement Membrane Deposits Following Allogeneic Hematopoietic Cell Transplant: A Report of 5 Cases. Am J Kidney Dis. 2022 Jun; 79(6):904-908. PMID: 34508832
     
  9. Molina Andújar A, Castrejon de Anta N, Rodriguez-Espinosa D, Hermida E, Larque AB, Esforzado N, Torregrosa JV, Cucchiari D, Blasco M, Rodríguez-Villar C, Beck LH, García Herrera A, Quintana LF. Antiphospholipase A2 receptor antibody-positive membranous nephropathy in the kidney donor: Lessons from a serendipitous transplantation. Am J Transplant. 2022 01; 22(1):299-303. PMID: 34431212
     
  10. Idrees N, Beck LH. Multitarget Combination Immunosuppressive Therapy for Primary Membranous Nephropathy. Am J Kidney Dis. 2021 12; 78(6):774-776. PMID: 34465505
     
Showing 10 of 86 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 86 publications over 18 distinct years, with a maximum of 14 publications in 2021

YearPublications
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20205
202114
20223

2019 American Society of Nephrology: Distinguished Researcher Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

anti-phospholipase A2 receptor autoantibodies
membranous nephropathy
PLA2R
Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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