Laertis Ikonomou, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

PhD, Université catholique de Louvain

Research interests include:
-Lung developmental biology
-Lung Epithelial Lineage Specification
-Development of new platforms for stem cell expansion and differentiation

Center Faculty Member
Boston University School of Medicine
Center for Regenerative Medicine

Biomechanical Determinants of Lung Cell Fate in Pluripotent Stem Cells
09/01/2014 - 04/30/2018 (PI)
NIH/National Heart, Lung, and Blood Inst

Defining the genetic program of primordial lung progenitors
12/01/2015 - 11/30/2017 (PI)
NIH/National Heart, Lung, and Blood Inst

Defining the genetic program of primordial lung progenitors
12/21/2011 - 11/30/2015 (PI)
NIH/National Heart, Lung, and Blood Inst

iPS cell modeling of ChILD syndrome caused by TTF1 mutations
01/31/2012 - 01/30/2014 (PI)
American Thoracic Society/ LUNGevity Fou

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Serra M, Alysandratos KD, Hawkins F, McCauley KB, Jacob A, Choi J, Caballero IS, Vedaie M, Kurmann AA, Ikonomou L, Hollenberg AN, Shannon JM, Kotton DN. Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification. Development. 2017 11 01; 144(21):3879-3893.View Related Profiles. PMID: 28947536.
  2. Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem. Am J Respir Crit Care Med. 2017 Apr 01; 195(7):P13-P14. PMID: 28362195; DOI: 10.1164/rccm.1957P13;.
  3. Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kandula MM, Monti S, Hollenberg AN, Mehta P, Kotton DN, Ikonomou L. Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1. Stem Cell Reports. 2017 Feb 14; 8(2):216-225.View Related Profiles. PMID: 28162994; DOI: 10.1016/j.stemcr.2016.12.024;.
  4. Ikonomou L, Freishtat RJ, Wagner DE, Panoskaltsis-Mortari A, Weiss DJ. The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act. Ann Am Thorac Soc. 2016 Aug; 13(8):1205-7. PMID: 27509147; DOI: 10.1513/AnnalsATS.201604-277ED;.
  5. Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 2015 Nov 5; 17(5):527-42.View Related Profiles. PMID: 26593959; PMCID: PMC4666682; DOI: 10.1016/j.stem.2015.09.004;.
  6. Ikonomou L, Kotton DN. Derivation of Endodermal Progenitors From Pluripotent Stem Cells. J Cell Physiol. 2015 Feb; 230(2):246-58.View Related Profiles. PMID: 25160562; PMCID: PMC4344429; DOI: 10.1002/jcp.24771;.
  7. Longmire TA, Ikonomou L, Kotton DN. Mouse ESC Differentiation to Nkx2.1+ Lung and Thyroid Progenitors. Bio Protoc. 2012 Nov 20; 2(22).View Related Profiles. PMID: 27453901.
  8. Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean JC, Kwok LW, Mou H, Rajagopal J, Shen SS, Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI, Kotton DN. Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012 Apr 6; 10(4):398-411.View Related Profiles. PMID: 22482505; PMCID: PMC3322392; DOI: 10.1016/j.stem.2012.01.019;.
  9. Diaz PI, Xie Z, Sobue T, Thompson A, Biyikoglu B, Ricker A, Ikonomou L, Dongari-Bagtzoglou A. Synergistic interaction between Candida albicans and commensal oral streptococci in a novel in vitro mucosal model. Infect Immun. 2012 Feb; 80(2):620-32. PMID: 22104105; PMCID: PMC3264323; DOI: 10.1128/IAI.05896-11;.
  10. Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED. Programmatic change: lung disease research in the era of induced pluripotency. Am J Physiol Lung Cell Mol Physiol. 2011 Dec; 301(6):L830-5.View Related Profiles. PMID: 21984571; PMCID: PMC3233828; DOI: 10.1152/ajplung.00255.2011;.
Showing 10 of 25 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 25 publications over 13 distinct years, with a maximum of 4 publications in 2010

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Embryonic stem cells
Lung Developmental Biology
Stem Cell Engineering

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

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