Koji Ohashi | Profiles RNS

Koji Ohashi, PhD

Associate Professor

Nagoya University

Websites

Postdoctoral Fellow (Previously held)
Boston University Chobanian & Avedisian School of Medicine

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Ozaki Y, Ohashi K, Otaka N, Kawanishi H, Takikawa T, Fang L, Takahara K, Tatsumi M, Ishihama S, Takefuji M, Kato K, Shimizu Y, Bando YK, Inoue A, Kuzuya M, Miura S, Murohara T, Ouchi N. Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1a pathway. Nat Commun. 2023 Aug 04; 14(1):4675. PMID: 37542026; PMCID: PMC10403505; DOI: 10.1038/s41467-023-40435-2;

Fang L, Ohashi K, Hayakawa S, Ogawa H, Otaka N, Kawanishi H, Takikawa T, Ozaki Y, Takahara K, Tatsumi M, Takefuji M, Shimizu Y, Bando YK, Fujishima Y, Maeda N, Shimomura I, Murohara T, Ouchi N. Adipolin protects against renal injury via PPARa-dependent reduction of inflammasome activation. iScience. 2023 May 19; 26(5):106591. PMID: 37250342; PMCID: PMC10214396; DOI: 10.1016/j.isci.2023.106591;

Ouchi N, Ohashi K, Murohara T. Recent progress in adipocytokine research. Nagoya J Med Sci. 2023 Feb; 85(1):23-26. PMID: 36923629; PMCID: PMC10009627; DOI: 10.18999/nagjms.85.1.23;

Ito M, Shibata R, Ohashi K, Otaka N, Yamaguchi S, Ogawa H, Enomoto T, Masutomi T, Murohara T, Ouchi N. Omentin Modulates Chronic Cardiac Remodeling After Myocardial Infarction. Circ Rep. 2023 Feb 10; 5(2):46-54. PMID: 36818520; PMCID: PMC9908527; DOI: 10.1253/circrep.CR-22-0079;

Fang L, Ohashi K, Otaka N, Ogawa H, Hiramatsu-Ito M, Kawanishi H, Bando YK, Shibata R, Shimizu Y, Kato K, Takikawa T, Ozaki Y, Takefuji M, Murohara T, Ouchi N. Omentin attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice. Cardiovasc Res. 2022 May 06; 118(6):1597-1610. PMID: 34051089

Suzuki K, Yamada H, Fujii R, Munetsuna E, Yamazaki M, Ando Y, Ohashi K, Ishikawa H, Mizuno G, Tsuboi Y, Hashimoto S, Hamajima N. Circulating microRNA-27a and -133a are negatively associated with incident hypertension: a five-year longitudinal population-based study. Biomarkers. 2022 Jul; 27(5):496-502. PMID: 35465807

Inooka D, Omori Y, Ouchi N, Ohashi K, Kawakami Y, Koyanagi Y, Koike C, Terasaki H, Nishiguchi KM, Ueno S. Ablation of Ctrp9, Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina. Invest Ophthalmol Vis Sci. 2022 May 02; 63(5):14. PMID: 35575905; PMCID: PMC9123514; DOI: 10.1167/iovs.63.5.14;

Fang L, Ohashi K, Ogawa H, Otaka N, Kawanishi H, Takikawa T, Ozaki Y, Takahara K, Tatsumi M, Takefuji M, Murohara T, Ouchi N. Factor Xa inhibitor, edoxaban ameliorates renal injury after subtotal nephrectomy by reducing epithelial-mesenchymal transition and inflammatory response. Physiol Rep. 2022 03; 10(5):e15218. PMID: 35262272; PMCID: PMC8905573; DOI: 10.14814/phy2.15218;

Ozaki Y, Ohashi K, Otaka N, Ogawa H, Kawanishi H, Takikawa T, Fang L, Tatsumi M, Takefuji M, Enomoto T, Darwish M, Iijima Y, Iijima T, Murohara T, Ouchi N. Neuron-derived neurotrophic factor protects against dexamethasone-induced skeletal muscle atrophy. Biochem Biophys Res Commun. 2022 02 19; 593:5-12. PMID: 35051783

Mori Y, Tsuchihira A, Yoshida T, Yoshida S, Fujiuchi A, Ohmi M, Isogai Y, Sakaguchi T, Eguchi S, Tsuda T, Kato K, Ohashi K, Ouchi N, Park HM, Murohara T, Takefuji M. Corticotropin releasing hormone receptor 2 antagonist, RQ-00490721, for the prevention of pressure overload-induced cardiac dysfunction. Biomed Pharmacother. 2022 Feb; 146:112566. PMID: 34954642

Showing 10 of 98 results. Show More

Ishihama S, Yoshida S, Yoshida T, Mori Y, Ouchi N, Eguchi S, Sakaguchi T, Tsuda T, Kato K, Shimizu Y, Ohashi K, Okumura T, Bando YK, Yagyu H, Wettschureck N, Kubota N, Offermanns S, Kadowaki T, Murohara T, Takefuji M. LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia. FASEB J. 2021 12; 35(12):e22048. PMID: 34807469

Tsuzuki K, Shimizu Y, Suzuki J, Pu Z, Yamaguchi S, Fujikawa Y, Kato K, Ohashi K, Takefuji M, Bando YK, Ouchi N, Calvert JW, Shibata R, Murohara T. Adverse Effect of Circadian Rhythm Disorder on Reparative Angiogenesis in Hind Limb Ischemia. J Am Heart Assoc. 2021 08 17; 10(16):e020896. PMID: 34348468; PMCID: PMC8475022; DOI: 10.1161/JAHA.121.020896;

Oishi H, Okumura T, Ohashi K, Kimura Y, Kazama S, Shibata N, Arao Y, Kato H, Kuwayama T, Yamaguchi S, Tatsumi M, Kondo T, Hiraiwa H, Morimoto R, Takefuji M, Ouchi N, Murohara T. Prognostic impact of transcardiac gradient of follistatin-like 1 reflecting hemodynamics in patients with dilated cardiomyopathy. J Cardiol. 2021 12; 78(6):524-532. PMID: 34334268

Mizuno G, Munetsuna E, Yamada H, Yamazaki M, Ando Y, Hattori Y, Kageyama I, Teshigawara A, Nouchi Y, Fujii R, Ishikawa H, Suzuki K, Hashimoto S, Ohashi K, Shimono Y. Maternal fructose consumption downregulates hippocampal catalase expression via DNA methylation in rat offspring. Nutr Res. 2021 Aug; 92:40-48. PMID: 34274553

Pu Z, Shimizu Y, Tsuzuki K, Suzuki J, Hayashida R, Kondo K, Fujikawa Y, Unno K, Ohashi K, Takefuji M, Bando YK, Ouchi N, Calvert JW, Shibata R, Murohara T. Important Role of Concomitant Lymphangiogenesis for Reparative Angiogenesis in Hindlimb Ischemia. Arterioscler Thromb Vasc Biol. 2021 06; 41(6):2006-2018. PMID: 33910373

Takikawa T, Ohashi K, Ogawa H, Otaka N, Kawanishi H, Fang L, Ozaki Y, Eguchi S, Tatsumi M, Takefuji M, Murohara T, Ouchi N. Adipolin/C1q/Tnf-related protein 12 prevents adverse cardiac remodeling after myocardial infarction. PLoS One. 2020; 15(12):e0243483. PMID: 33275602; PMCID: PMC7717554; DOI: 10.1371/journal.pone.0243483;

Yamaguchi S, Shibata R, Ohashi K, Enomoto T, Ogawa H, Otaka N, Hiramatsu-Ito M, Masutomi T, Kawanishi H, Murohara T, Ouchi N. C1q/TNF-Related Protein 9 Promotes Revascularization in Response to Ischemia via an eNOS-Dependent Manner. Front Pharmacol. 2020; 11:1313. PMID: 32973529; PMCID: PMC7472599; DOI: 10.3389/fphar.2020.01313;

Kawanishi H, Ohashi K, Ogawa H, Otaka N, Takikawa T, Fang L, Ozaki Y, Takefuji M, Murohara T, Ouchi N. A novel selective PPARa modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanisms. PLoS One. 2020; 15(6):e0235362. PMID: 32584895; PMCID: PMC7316279; DOI: 10.1371/journal.pone.0235362;

Ohashi K, Ouchi N, Murohara T. Can Pharmacological Ischemic Preconditioning Affect Myocardial Ischemic Injury? Circ J. 2020 05 25; 84(6):891-893. PMID: 32336722

Kitagawa A, Ohta Y, Ohashi K, Yashiro K, Fukuzawa K. Effect of High Fructose-Induced Metabolic Syndrome on Tissue Vitamin E and Lipid Peroxide Levels in Rats. J Nutr Sci Vitaminol (Tokyo). 2020; 66(2):200-206. PMID: 32350182

Ogawa H, Ohashi K, Ito M, Shibata R, Kanemura N, Yuasa D, Kambara T, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Otaka N, Kawanishi H, Yamaguchi S, Enomoto T, Abe T, Kaneko M, Takefuji M, Murohara T, Ouchi N. Adipolin/CTRP12 protects against pathological vascular remodelling through suppression of smooth muscle cell growth and macrophage inflammatory response. Cardiovasc Res. 2020 01 01; 116(1):237-249. PMID: 30874788

Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, Shimizu Y, Bando YK, Ohashi K, Ouchi N, Enomoto A, Offermanns S, Kaibuchi K, Murohara T. Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin. Circulation. 2019 11 19; 140(21):1737-1752. PMID: 31564129

Yamada H, Munetsuna E, Yamazaki M, Mizuno G, Sadamoto N, Ando Y, Fujii R, Shiogama K, Ishikawa H, Suzuki K, Shimono Y, Ohashi K, Hashimoto S. Maternal fructose-induced oxidative stress occurs viaTfam and Ucp5 epigenetic regulation in offspring hippocampi. FASEB J. 2019 10; 33(10):11431-11442. PMID: 31314594

Eguchi S, Takefuji M, Sakaguchi T, Ishihama S, Mori Y, Tsuda T, Takikawa T, Yoshida T, Ohashi K, Shimizu Y, Hayashida R, Kondo K, Bando YK, Ouchi N, Murohara T. Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction. J Biol Chem. 2019 08 02; 294(31):11665-11674. PMID: 31217281; PMCID: PMC6682734; DOI: 10.1074/jbc.RA119.007537;

Aikawa T, Shimada K, Miyauchi K, Miyazaki T, Sai E, Ouchi S, Kadoguchi T, Kunimoto M, Joki Y, Dohi T, Okazaki S, Isoda K, Ohashi K, Murohara T, Ouchi N, Daida H. Associations among circulating levels of follistatin-like 1, clinical parameters, and cardiovascular events in patients undergoing elective percutaneous coronary intervention with drug-eluting stents. PLoS One. 2019; 14(4):e0216297. PMID: 31034503; PMCID: PMC6488088; DOI: 10.1371/journal.pone.0216297;

Otaka N, Shibata R, Ohashi K, Uemura Y, Kambara T, Enomoto T, Ogawa H, Ito M, Kawanishi H, Maruyama S, Joki Y, Fujikawa Y, Narita S, Unno K, Kawamoto Y, Murate T, Murohara T, Ouchi N. Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury. Circ Res. 2018 12 07; 123(12):1326-1338.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 30566056

Lau WB, Ohashi K, Wang Y, Ogawa H, Murohara T, Ma XL, Ouchi N. Role of Adipokines in Cardiovascular Disease. Circ J. 2017 Jun 23; 81(7):920-928. PMID: 28603178

Shibata R, Ouchi N, Ohashi K, Murohara T. The role of adipokines in cardiovascular disease. J Cardiol. 2017 Oct; 70(4):329-334. PMID: 28325521; DOI: 10.1016/j.jjcc.2017.02.006;

Kanemura N, Shibata R, Ohashi K, Ogawa H, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Otaka N, Murohara T, Ouchi N. C1q/TNF-related protein 1 prevents neointimal formation after arterial injury. Atherosclerosis. 2017 Feb; 257:138-145. PMID: 28131048; DOI: 10.1016/j.atherosclerosis.2017.01.014;

Ouchi N, Ohashi K, Shibata R, Murohara T. Protective Roles of Adipocytokines and Myokines in Cardiovascular Disease. Circ J. 2016 Sep 23; 80(10):2073-80. PMID: 27581346; DOI: 10.1253/circj.CJ-16-0663;

Hayakawa S, Ohashi K, Shibata R, Takahashi R, Otaka N, Ogawa H, Ito M, Kanemura N, Hiramatsu-Ito M, Ikeda N, Murohara T, Ouchi N. Association of Circulating Follistatin-Like 1 Levels with Inflammatory and Oxidative Stress Markers in Healthy Men. PLoS One. 2016; 11(5):e0153619. PMID: 27145224; PMCID: PMC4856269; DOI: 10.1371/journal.pone.0153619;

Hiramatsu-Ito M, Shibata R, Ohashi K, Uemura Y, Kanemura N, Kambara T, Enomoto T, Yuasa D, Matsuo K, Ito M, Hayakawa S, Ogawa H, Otaka N, Kihara S, Murohara T, Ouchi N. Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice. Cardiovasc Res. 2016 May 01; 110(1):107-17. PMID: 26714927; DOI: 10.1093/cvr/cvv282;

Yuasa D, Ohashi K, Shibata R, Mizutani N, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Kanemura N, Hayakawa S, Hiramatsu-Ito M, Ito M, Ogawa H, Murate T, Murohara T, Ouchi N. C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart. FASEB J. 2016 Mar; 30(3):1065-75. PMID: 26578687; DOI: 10.1096/fj.15-279885;

Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N. C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism. Mol Cell Biol. 2015 Jun; 35(12):2173-85.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Aprahamian, Tamar

PMID: 25870106; PMCID: PMC4438248; DOI: 10.1128/MCB.01518-14;

Joki Y, Ohashi K, Yuasa D, Shibata R, Ito M, Matsuo K, Kambara T, Uemura Y, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ogawa H, Daida H, Murohara T, Ouchi N. FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism. Biochem Biophys Res Commun. 2015 Mar 27; 459(1):124-30. PMID: 25712519; DOI: 10.1016/j.bbrc.2015.02.081;

Joki Y, Ohashi K, Yuasa D, Shibata R, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ito M, Ogawa H, Daida H, Murohara T, Ouchi N. Neuron-derived neurotrophic factor ameliorates adverse cardiac remodeling after experimental myocardial infarction. Circ Heart Fail. 2015 Mar; 8(2):342-51. PMID: 25654972; DOI: 10.1161/CIRCHEARTFAILURE.114.001647;

Ohashi K, Yuasa D, Shibata R, Murohara T, Ouchi N. Adiponectin as a Target in Obesity-related Inflammatory State. Endocr Metab Immune Disord Drug Targets. 2015; 15(2):145-50. PMID: 25772181

Matsuo K, Shibata R, Ohashi K, Kambara T, Uemura Y, Hiramatsu-Ito M, Enomoto T, Yuasa D, Joki Y, Ito M, Hayakawa S, Ogawa H, Kihara S, Murohara T, Ouchi N. Omentin functions to attenuate cardiac hypertrophic response. J Mol Cell Cardiol. 2015 Feb; 79:195-202. PMID: 25479337; DOI: 10.1016/j.yjmcc.2014.11.019;

Uemura Y, Shibata R, Kanemura N, Ohashi K, Kambara T, Hiramatsu-Ito M, Enomoto T, Yuasa D, Joki Y, Matsuo K, Ito M, Hayakawa S, Ogawa H, Murohara T, Ouchi N. Adipose-derived protein omentin prevents neointimal formation after arterial injury. FASEB J. 2015 Jan; 29(1):141-51. PMID: 25300621; DOI: 10.1096/fj.14-258129;

Watanabe Y, Shibata R, Ouchi N, Kambara T, Ohashi K, Jie L, Inoue Y, Murohara T, Komori K. Adiponectin ameliorates endotoxin-induced acute cardiac injury. Biomed Res Int. 2014; 2014:382035. PMID: 25180179; PMCID: PMC4142376; DOI: 10.1155/2014/382035;

Hayakawa S, Ohashi K, Shibata R, Kataoka Y, Miyabe M, Enomoto T, Joki Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Ogawa H, Matsuo K, Hiramatsu-Ito M, van den Hoff MJ, Walsh K, Murohara T, Ouchi N. Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model. J Am Soc Nephrol. 2015 Mar; 26(3):636-46.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 25071081; PMCID: PMC4341480; DOI: 10.1681/ASN.2014020210;

Shibata R, Ohashi K, Murohara T, Ouchi N. The potential of adipokines as therapeutic agents for cardiovascular disease. Cytokine Growth Factor Rev. 2014 Aug; 25(4):483-7. PMID: 25066649; DOI: 10.1016/j.cytogfr.2014.07.005;

Yuasa D, Ohashi K, Shibata R, Takeshita K, Kikuchi R, Takahashi R, Kataoka Y, Miyabe M, Joki Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Ito M, Ikeda N, Murohara T, Ouchi N. Association of circulating C1q/TNF-related protein 1 levels with coronary artery disease in men. PLoS One. 2014; 9(6):e99846.View Related Profiles.

Ohashi, Koji
Kikuchi, Ryosuke

PMID: 24945145; PMCID: PMC4063765; DOI: 10.1371/journal.pone.0099846;

Kataoka Y, Shibata R, Ohashi K, Kambara T, Enomoto T, Uemura Y, Ogura Y, Yuasa D, Matsuo K, Nagata T, Oba T, Yasukawa H, Numaguchi Y, Sone T, Murohara T, Ouchi N. Omentin prevents myocardial ischemic injury through AMP-activated protein kinase- and Akt-dependent mechanisms. J Am Coll Cardiol. 2014 Jun 24; 63(24):2722-33. PMID: 24768874; DOI: 10.1016/j.jacc.2014.03.032;

Ohashi K, Shibata R, Murohara T, Ouchi N. Role of anti-inflammatory adipokines in obesity-related diseases. Trends Endocrinol Metab. 2014 Jul; 25(7):348-55. PMID: 24746980; DOI: 10.1016/j.tem.2014.03.009;

Miyabe M, Ohashi K, Shibata R, Uemura Y, Ogura Y, Yuasa D, Kambara T, Kataoka Y, Yamamoto T, Matsuo K, Joki Y, Enomoto T, Hayakawa S, Hiramatsu-Ito M, Ito M, Van Den Hoff MJ, Walsh K, Murohara T, Ouchi N. Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury. Cardiovasc Res. 2014 Jul 1; 103(1):111-20.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 24743592; PMCID: PMC4834864; DOI: 10.1093/cvr/cvu105;

Ohashi K, Enomoto T, Joki Y, Shibata R, Ogura Y, Kataoka Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Murohara T, Ouchi N. Neuron-derived neurotrophic factor functions as a novel modulator that enhances endothelial cell function and revascularization processes. J Biol Chem. 2014 May 16; 289(20):14132-44. PMID: 24706764; PMCID: PMC4022881; DOI: 10.1074/jbc.M114.555789;

Enomoto T, Ohashi K, Shibata R, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Miyabe M, Matsuo K, Joki Y, Hayakawa S, Hiramatsu-Ito M, Ito M, Murohara T, Ouchi N. Transcriptional regulation of an insulin-sensitizing adipokine adipolin/CTRP12 in adipocytes by Krüppel-like factor 15. PLoS One. 2013; 8(12):e83183. PMID: 24358263; PMCID: PMC3865152; DOI: 10.1371/journal.pone.0083183;

Shimizu Y, Shibata R, Ishii M, Ohashi K, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Kihara S, Murohara T, Ouchi N. Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema. J Am Heart Assoc. 2013 Oct; 2(5):e000438. PMID: 24052499; PMCID: PMC3835259; DOI: 10.1161/JAHA.113.000438;

Enomoto T, Shibata R, Ohashi K, Kambara T, Kataoka Y, Uemura Y, Yuasa D, Murohara T, Ouchi N. Regulation of adipolin/CTRP12 cleavage by obesity. Biochem Biophys Res Commun. 2012 Nov 9; 428(1):155-9. PMID: 23068097; DOI: 10.1016/j.bbrc.2012.10.031;

Uemura Y, Shibata R, Ohashi K, Enomoto T, Kambara T, Yamamoto T, Ogura Y, Yuasa D, Joki Y, Matsuo K, Miyabe M, Kataoka Y, Murohara T, Ouchi N. Adipose-derived factor CTRP9 attenuates vascular smooth muscle cell proliferation and neointimal formation. FASEB J. 2013 Jan; 27(1):25-33. PMID: 22972916; DOI: 10.1096/fj.12-213744;

Ogura Y, Ouchi N, Ohashi K, Shibata R, Kataoka Y, Kambara T, Kito T, Maruyama S, Yuasa D, Matsuo K, Enomoto T, Uemura Y, Miyabe M, Ishii M, Yamamoto T, Shimizu Y, Walsh K, Murohara T. Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Circulation. 2012 Oct 2; 126(14):1728-38.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 22929303; PMCID: PMC3548325; DOI: 10.1161/CIRCULATIONAHA.112.115089;

Shibata R, Ouchi N, Takahashi R, Terakura Y, Ohashi K, Ikeda N, Higuchi A, Terasaki H, Kihara S, Murohara T. Omentin as a novel biomarker of metabolic risk factors. Diabetol Metab Syndr. 2012; 4(1):37. PMID: 22835063; PMCID: PMC3411496; DOI: 10.1186/1758-5996-4-37;

Ohashi K, Ouchi N, Matsuzawa Y. Anti-inflammatory and anti-atherogenic properties of adiponectin. Biochimie. 2012 Oct; 94(10):2137-42. PMID: 22713764; DOI: 10.1016/j.biochi.2012.06.008;

Kambara T, Ohashi K, Shibata R, Ogura Y, Maruyama S, Enomoto T, Uemura Y, Shimizu Y, Yuasa D, Matsuo K, Miyabe M, Kataoka Y, Murohara T, Ouchi N. CTRP9 protein protects against myocardial injury following ischemia-reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanism. J Biol Chem. 2012 Jun 1; 287(23):18965-73.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 22514273; PMCID: PMC3365930; DOI: 10.1074/jbc.M112.357939;

Ouchi N, Ohashi K, Shibata R, Murohara T. Adipocytokines and obesity-linked disorders. Nagoya J Med Sci. 2012 Feb; 74(1-2):19-30. PMID: 22515108; PMCID: PMC4831247

Kitagawa A, Ohta Y, Ohashi K. Melatonin improves metabolic syndrome induced by high fructose intake in rats. J Pineal Res. 2012 May; 52(4):403-13. PMID: 22220562; DOI: 10.1111/j.1600-079X.2011.00955.x;

Maruyama S, Shibata R, Kikuchi R, Izumiya Y, Rokutanda T, Araki S, Kataoka Y, Ohashi K, Daida H, Kihara S, Ogawa H, Murohara T, Ouchi N. Fat-derived factor omentin stimulates endothelial cell function and ischemia-induced revascularization via endothelial nitric oxide synthase-dependent mechanism. J Biol Chem. 2012 Jan 2; 287(1):408-17.View Related Profiles.

Ohashi, Koji
Kikuchi, Ryosuke
Maruyama, Sonomi

PMID: 22081609; PMCID: PMC3249092; DOI: 10.1074/jbc.M111.261818;

Shimano M, Ouchi N, Nakamura K, van Wijk B, Ohashi K, Asaumi Y, Higuchi A, Pimentel DR, Sam F, Murohara T, van den Hoff MJ, Walsh K. Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E899-906.View Related Profiles.

Pimentel, David
Sam, Flora
Nakamura, Kazuto
Walsh, Kenneth
Ohashi, Koji
Asaumi, Yasuhide

PMID: 21987816; PMCID: PMC3203781; DOI: 10.1073/pnas.1108559108;

Shibata R, Ouchi N, Kikuchi R, Takahashi R, Takeshita K, Kataoka Y, Ohashi K, Ikeda N, Kihara S, Murohara T. Circulating omentin is associated with coronary artery disease in men. Atherosclerosis. 2011 Dec; 219(2):811-4.View Related Profiles.

Ohashi, Koji
Kikuchi, Ryosuke

PMID: 21925659; DOI: 10.1016/j.atherosclerosis.2011.08.017;

Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y, Walsh K, Murohara T, Ouchi N. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. J Biol Chem. 2011 Oct 7; 286(40):34552-8.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 21849507; PMCID: PMC3186379; DOI: 10.1074/jbc.M111.277319;

Shibata R, Takahashi R, Kataoka Y, Ohashi K, Ikeda N, Kihara S, Murohara T, Ouchi N. Association of a fat-derived plasma protein omentin with carotid artery intima-media thickness in apparently healthy men. Hypertens Res. 2011 Dec; 34(12):1309-12. PMID: 21814208; DOI: 10.1038/hr.2011.130;

Hayashi M, Shibata R, Takahashi H, Ishii H, Aoyama T, Kasuga H, Yamada S, Ohashi K, Maruyama S, Matsuo S, Ouchi N, Murohara T, Toriyama T. Association of adiponectin with carotid arteriosclerosis in predialysis chronic kidney disease. Am J Nephrol. 2011; 34(3):249-55. PMID: 21791921; DOI: 10.1159/000330178;

Maruyama S, Shibata R, Ohashi K, Ohashi T, Daida H, Walsh K, Murohara T, Ouchi N. Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism. J Biol Chem. 2011 Sep 16; 286(37):32790-800.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 21784858; PMCID: PMC3173230; DOI: 10.1074/jbc.M111.245985;

Essick EE, Ouchi N, Wilson RM, Ohashi K, Ghobrial J, Shibata R, Pimentel DR, Sam F. Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3):H984-93.View Related Profiles.

Pimentel, David
Sam, Flora
Ohashi, Koji

PMID: 21666115; PMCID: PMC3191107; DOI: 10.1152/ajpheart.00428.2011;

Ohashi K, Ouchi N, Matsuzawa Y. Adiponectin and hypertension. Am J Hypertens. 2011 Mar; 24(3):263-9. PMID: 20930707; DOI: 10.1038/ajh.2010.216;

Li P, Shibata R, Maruyama S, Kondo M, Ohashi K, Ouchi N, Murohara T. Fenofibrate promotes ischemia-induced revascularization through the adiponectin-dependent pathway. Am J Physiol Endocrinol Metab. 2010 Oct; 299(4):E560-6.View Related Profiles.

Ohashi, Koji
Maruyama, Sonomi

PMID: 20663986; DOI: 10.1152/ajpendo.00284.2010;

Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A, Walsh K. Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science. 2010 Jul 23; 329(5990):454-7.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Gokce, Noyan

PMID: 20558665; PMCID: PMC3132938; DOI: 10.1126/science.1188280;

Ohashi K, Ouchi N, Higuchi A, Shaw RJ, Walsh K. LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. J Biol Chem. 2010 Jul 16; 285(29):22291-8.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 20489196; PMCID: PMC2903404; DOI: 10.1074/jbc.M110.123794;

Shimano M, Ouchi N, Shibata R, Ohashi K, Pimentel DR, Murohara T, Walsh K. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. J Mol Cell Cardiol. 2010 Aug; 49(2):210-20.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 20206634; PMCID: PMC2885542; DOI: 10.1016/j.yjmcc.2010.02.021;

McCalmon SA, Desjardins DM, Ahmad S, Davidoff KS, Snyder CM, Sato K, Ohashi K, Kielbasa OM, Mathew M, Ewen EP, Walsh K, Gavras H, Naya FJ. Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2. Circ Res. 2010 Mar 19; 106(5):952-60.View Related Profiles.

Gavras, Haralambos
Ohashi, Koji

PMID: 20093629; PMCID: PMC2858324; DOI: 10.1161/CIRCRESAHA.109.209007;

Ouchi N, Asaumi Y, Ohashi K, Higuchi A, Sono-Romanelli S, Oshima Y, Walsh K. DIP2A functions as a FSTL1 receptor. J Biol Chem. 2010 Mar 5; 285(10):7127-34.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Asaumi, Yasuhide

PMID: 20054002; PMCID: PMC2844162; DOI: 10.1074/jbc.M109.069468;

Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem. 2010 Feb 26; 285(9):6153-60.View Related Profiles.

Vita, Joseph
Walsh, Kenneth
Ohashi, Koji
Gokce, Noyan
Summer, Ross

PMID: 20028977; PMCID: PMC2825410; DOI: 10.1074/jbc.M109.088708;

Higuchi A, Ohashi K, Shibata R, Sono-Romanelli S, Walsh K, Ouchi N. Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism. Arterioscler Thromb Vasc Biol. 2010 Jan; 30(1):46-53.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19910632; PMCID: PMC3552615; DOI: 10.1161/ATVBAHA.109.198465;

Sam F, Duhaney TA, Sato K, Wilson RM, Ohashi K, Sono-Romanelli S, Higuchi A, De Silva DS, Qin F, Walsh K, Ouchi N. Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure. Endocrinology. 2010 Jan; 151(1):322-31.View Related Profiles.

Sam, Flora
Qin, Fuzhong
Walsh, Kenneth
Ohashi, Koji

PMID: 19850745; PMCID: PMC2803144; DOI: 10.1210/en.2009-0806;

Ohashi K, Ouchi N, Sato K, Higuchi A, Ishikawa TO, Herschman HR, Kihara S, Walsh K. Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Mol Cell Biol. 2009 Jul; 29(13):3487-99.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19398582; PMCID: PMC2698754; DOI: 10.1128/MCB.00126-09;

Higuchi A, Ohashi K, Kihara S, Walsh K, Ouchi N. Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression. Circ Res. 2009 May 8; 104(9):1058-65.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19342600; PMCID: PMC2740643; DOI: 10.1161/CIRCRESAHA.109.194506;

Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K. Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism. J Biol Chem. 2008 Nov 21; 283(47):32802-11.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 18718903; PMCID: PMC2583310; DOI: 10.1074/jbc.M803440200;

Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K. Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. FEBS Lett. 2008 Apr 2; 582(7):1147-50.View Related Profiles.

Pimentel, David
Ohashi, Koji

PMID: 18339320; PMCID: PMC2423200; DOI: 10.1016/j.febslet.2008.03.002;

Fujita K, Maeda N, Sonoda M, Ohashi K, Hibuse T, Nishizawa H, Nishida M, Hiuge A, Kurata A, Kihara S, Shimomura I, Funahashi T. Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha. Arterioscler Thromb Vasc Biol. 2008 May; 28(5):863-70. PMID: 18309113; DOI: 10.1161/ATVBAHA.107.156687;

Ohashi K, Iwatani H, Kihara S, Nakagawa Y, Komura N, Fujita K, Maeda N, Nishida M, Katsube F, Shimomura I, Ito T, Funahashi T. Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice. Arterioscler Thromb Vasc Biol. 2007 Sep; 27(9):1910-7. PMID: 17626903

Ohashi K, Yamazaki T, Kitamura S, Ohta S, Izumi S, Kominami S. Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme. Biochim Biophys Acta. 2007 Feb; 1770(2):231-40. PMID: 17098364

Ohashi K, Funahashi T. [Mutations and polymorphisms in adiponectin gene]. Nihon Rinsho. 2006 Sep 28; Suppl 3:264-8. PMID: 17022543

Ohashi K, Funahashi T. [Adiponectin]. Nihon Rinsho. 2006 Jul; 64 Suppl 5:163-7. PMID: 16895181

Ohashi K, Kihara S, Ouchi N, Kumada M, Fujita K, Hiuge A, Hibuse T, Ryo M, Nishizawa H, Maeda N, Maeda K, Shibata R, Walsh K, Funahashi T, Shimomura I. Adiponectin replenishment ameliorates obesity-related hypertension. Hypertension. 2006 Jun; 47(6):1108-16. PMID: 16651465

Muranaka K, Yanagi Y, Tamaki Y, Takahashi H, Usui T, Ohashi K, Matsuoka H, Senda T. Suppression of laser-induced choroidal neovascularization by oral administration of SA3443 in mice. FEBS Lett. 2005 Nov 7; 579(27):6084-8. PMID: 16229837

Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med. 2005 Oct; 11(10):1096-103.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 16155579; PMCID: PMC2828682; DOI: 10.1038/nm1295;

Iwashima Y, Katsuya T, Ishikawa K, Kida I, Ohishi M, Horio T, Ouchi N, Ohashi K, Kihara S, Funahashi T, Rakugi H, Ogihara T. Association of hypoadiponectinemia with smoking habit in men. Hypertension. 2005 Jun; 45(6):1094-100. PMID: 15897361

Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med. 2004 Dec; 10(12):1384-9.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji
Colucci, Wilson

PMID: 15558058; PMCID: PMC2828675

Ohashi K, Kominami S, Yamazaki T, Ohta S, Kitamura S. Inhibitory effect of organotin compounds on rat neuronal nitric oxide synthase through interaction with calmodulin. Biochem Biophys Res Commun. 2004 Nov 5; 324(1):178-85. PMID: 15464999

Iwashima Y, Katsuya T, Ishikawa K, Ouchi N, Ohishi M, Sugimoto K, Fu Y, Motone M, Yamamoto K, Matsuo A, Ohashi K, Kihara S, Funahashi T, Rakugi H, Matsuzawa Y, Ogihara T. Hypoadiponectinemia is an independent risk factor for hypertension. Hypertension. 2004 Jun; 43(6):1318-23. PMID: 15123570

Kumada M, Kihara S, Ouchi N, Kobayashi H, Okamoto Y, Ohashi K, Maeda K, Nagaretani H, Kishida K, Maeda N, Nagasawa A, Funahashi T, Matsuzawa Y. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation. 2004 May 4; 109(17):2046-9. PMID: 15096450

Ohashi K, Ouchi N, Kihara S, Funahashi T, Nakamura T, Sumitsuji S, Kawamoto T, Matsumoto S, Nagaretani H, Kumada M, Okamoto Y, Nishizawa H, Kishida K, Maeda N, Hiraoka H, Iwashima Y, Ishikawa K, Ohishi M, Katsuya T, Rakugi H, Ogihara T, Matsuzawa Y. Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease. J Am Coll Cardiol. 2004 Apr 7; 43(7):1195-200. PMID: 15063429

Ouchi N, Ohishi M, Kihara S, Funahashi T, Nakamura T, Nagaretani H, Kumada M, Ohashi K, Okamoto Y, Nishizawa H, Kishida K, Maeda N, Nagasawa A, Kobayashi H, Hiraoka H, Komai N, Kaibe M, Rakugi H, Ogihara T, Matsuzawa Y. Association of hypoadiponectinemia with impaired vasoreactivity. Hypertension. 2003 Sep; 42(3):231-4. PMID: 12860835

Kishida K, Nagaretani H, Kondo H, Kobayashi H, Tanaka S, Maeda N, Nagasawa A, Hibuse T, Ohashi K, Kumada M, Nishizawa H, Okamoto Y, Ouchi N, Maeda K, Kihara S, Funahashi T, Matsuzawa Y. Disturbed secretion of mutant adiponectin associated with the metabolic syndrome. Biochem Biophys Res Commun. 2003 Jun 20; 306(1):286-92. PMID: 12788102

Sakai N, Uchida Y, Ohashi K, Hibuse T, Saika Y, Tomari Y, Kihara S, Hiraoka H, Nakamura T, Ito S, Yamashita S, Matsuzawa Y. Measurement of fasting serum apoB-48 levels in normolipidemic and hyperlipidemic subjects by ELISA. J Lipid Res. 2003 Jun; 44(6):1256-62. PMID: 12671037

Ouchi N, Kihara S, Funahashi T, Nakamura T, Nishida M, Kumada M, Okamoto Y, Ohashi K, Nagaretani H, Kishida K, Nishizawa H, Maeda N, Kobayashi H, Hiraoka H, Matsuzawa Y. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation. 2003 Feb 11; 107(5):671-4. PMID: 12578865

Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, Ohashi K, Sakai N, Shimomura I, Kobayashi H, Terasaka N, Inaba T, Funahashi T, Matsuzawa Y. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2002 Nov 26; 106(22):2767-70. PMID: 12451000

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 98 publications over 22 distinct years, with a maximum of 10 publications in 2014

Bar chart showing 98 publications over 22 distinct years, with a maximum of 10 publications in 2014

Year	Publications
2002	1
2003	4
2004	5
2005	3
2006	4
2007	1
2008	3
2009	5
2010	7
2011	8
2012	8
2013	2
2014	10
2015	6
2016	2
2017	3
2018	1
2019	4
2020	6
2021	6
2022	5
2023	4

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