Katrina Kezios | Profiles RNS

Katrina Kezios, PhD

Assistant Professor

Boston University School of Public Health

Epidemiology

PhD, Columbia University
MPH, Columbia University
BS, North Carolina State University

Pronouns: she/her/hers

Katrina Kezios is a life course epidemiologist and Assistant Professor in the Department of Epidemiology at the Boston University School of Public Health. She received her MPH and PhD in Epidemiology from Columbia University, where she completed an interdisciplinary NIEHS T32 predoctoral fellowship in Environmental Life Course Epidemiology.

Dr. Kezios’s research centers on the life course biosocial determinants of aging-related processes and outcomes, and she has worked on studies that collectively span the life course—from birth cohorts to aging cohorts. A primary focus of her applied work is understanding how chronic exposure to social and financial stressors harms cognition and impacts dementia risk. In much of this work, she employs novel methods to overcome challenges in life course research, leveraging her expertise in life course theory and methods, epidemiologic methods, and causal inference. She is currently the PI of an NIA funded study that uses data fusion methods to construct a longitudinal synthetic cohort to examine how life course financial wellbeing shapes cognitive aging.

Dr. Kezios also leads meta-research studies evaluating how core concepts and principles in epidemiologic training are reflected in research practice, a research area influenced by her experience teaching epidemiologic methods.

BU Research

Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohort (AG084769)
05/01/2025 - 04/30/2028 (PI)
NIH/National Institute on Aging
4R00AG084769-03

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Kezios KL, Liu J, Murchland AR, Zeki Al Hazzouri A, Aiello AE, Koenen K, Hayes-Larson E. Incident traumatic experiences and poor financial well-being: A double hit for cognitive decline? Alzheimers Dement (Amst). 2025; 17(4):e70226. PMID: 41393809; PMCID: PMC12696043; DOI: 10.1002/dad2.70226;

Nichols E, Bindas A, Atshan S, Chang H, Chiang YY, Claus Henn B, Hayes-Larson E, Keller KP, Kezios KL, Shih RA, Szpiro AA, Weiss J, Adar SD, Knapp DM, Lee J, Weuve J. Modeling approaches for estimating the effects of risk factors using longitudinal lifecourse exposure data in dementia research. Alzheimers Dement. 2025 Dec; 21(12):e70971.View Related Profiles.

Claus Henn, Birgit
Weuve, Jennifer
Kezios, Katrina

PMID: 41319155; PMCID: PMC12665171; DOI: 10.1002/alz.70971;

Colvin CL, Moropoulos KN, Yu X, Elbejjani M, Glymour MM, Zeki Al Hazzouri A, Kezios KL. Cumulative poverty across early adulthood and midlife cognition: findings from the national longitudinal survey of youth. J Epidemiol Community Health. 2025 Nov 27. PMID: 41309211; DOI: 10.1136/jech-2025-224920;

Yu X, Kezios KL, Lu P, Swift SL, Zeki Al Hazzouri A. Cumulative supplemental nutrition assistance program participation and memory aging among US older adults, 1996-2018. Prev Med. 2026 Jan; 202:108472. PMID: 41285226; DOI: 10.1016/j.ypmed.2025.108472;

Teferi HM, Shelton RC, Conneely KN, De Vivo I, Factor-Litvak P, Kezios KL, Cirillo PM, Cohn BA, Link BG, Suglia SF. Allostatic load and biological aging among middle aged adults. Psychoneuroendocrinology. 2026 Jan; 183:107661. PMID: 41223677; DOI: 10.1016/j.psyneuen.2025.107661;

Colvin CL, Swift SL, Yu X, Kezios KL, Al Hazzouri AZ. Investigating associations between long-term poverty exposure and premature mortality: evidence from the National Longitudinal Survey of Youth 1979 prospective cohort. Lancet Public Health. 2025 Nov; 10(11):e971-e978. PMID: 41162130; PMCID: PMC12638018; DOI: 10.1016/S2468-2667(25)00227-0;

Swift SL, Chen Z, Colvin C, Kezios K, Calonico S, Al Hazzouri AZ. Unsecured debt in early adulthood and premature mortality in adults in the USA: a longitudinal analysis of prospective national cohort data. Lancet Public Health. 2025 Nov; 10(11):e979-e987. PMID: 41162131; PMCID: PMC12700172; DOI: 10.1016/S2468-2667(25)00226-9;

Nichols E, Keller KP, Chang H, Chiang YY, Gross AL, Hayes-Larson E, Claus Henn B, Kezios KL, Meijer E, Shih RA, Szpiro AA, Weiss J, Weuve J, Adar SD, Lee J. Key research priorities in methodological approaches for measuring the exposome and studying its role in the development of dementia. Alzheimers Dement. 2025 Nov; 21(11):e70928.View Related Profiles.

Claus Henn, Birgit
Weuve, Jennifer
Kezios, Katrina

PMID: 41273229; PMCID: PMC12639404; DOI: 10.1002/alz.70928;

Mani SS, Kezios KL, Delaporte M, Cho TC, Rojas-Saunero LP, Weuve J, Avila-Rieger J, Kobayashi LC. Later-life cognitive function at the intersection of gender and occupation across Harmonized Cognitive Assessment Protocols (HCAPs) in the United States, Chile, Mexico, India, and South Africa. Alzheimers Dement. 2025 Nov; 21(11):e70923.View Related Profiles.

Weuve, Jennifer
Kezios, Katrina

PMID: 41311298; PMCID: PMC12661120; DOI: 10.1002/alz.70923;

Mesa RA, Llabre MM, Lee DJ, Rundek T, Kezios KL, Al Hazzouri AZ, Elfassy T. Social determinants of health and biological age among diverse U.S. Adults, NHANES 2011-2018. BMC Public Health. 2025 Sep 30; 25(1):3215. PMID: 41029576; PMCID: PMC12486641; DOI: 10.1186/s12889-025-23803-z;

Showing 10 of 52 results. Show More

Moubadder L, Chen J, Clausing ES, Kezios KL, Conneely KN, Factor-Litvak P, Prada D, Baccarelli A, Shelton RC, Link BG, Suglia SF. Impact of socioeconomic conditions across the life course on epigenetic age acceleration: evidence from a longitudinal cohort. J Gerontol A Biol Sci Med Sci. 2025 Sep 19; 80(10). PMID: 40644330; DOI: 10.1093/gerona/glaf139;

Choi M, Zimmerman SC, Buto PT, Wang J, Brenowitz WD, Hoffmann TJ, Hazzouri AZA, Kezios K, Glymour MM. Association of genetic risk score for Alzheimer's disease with late-life body mass index in all of us: Evaluating reverse causation. Alzheimers Dement. 2025 Apr; 21(4):e14598.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 40189781; PMCID: PMC11972977; DOI: 10.1002/alz.14598;

Levy NS, Kezios KL. The Same but Different?: A Systematic Review of the Impact of Selection and Collider Bias on Internal Validity. Epidemiology. 2025 Jul 01; 36(4):473-481. PMID: 40167168; PMCID: PMC12122217; DOI: 10.1097/EDE.0000000000001864;

Hayes-Larson E, Andrews RM, Kezios KL, Bercu A, Rouanet A, Helmer C, Crane PK, Gibbons LE, Klinedinst BS, McEvoy LK, Nichols E, Weuve J, Rajan KB, Hwang PH, Mez J, Farina M, Shaw C, Sims KD, Therneau T, Petersen RC, Bouteloup V, Gross AL, Albert M, Morris JC, Masters CL, Resnick SM, Maruff P, Manly JJ, Turney IC, Vonk JMJ, Avila-Rieger J, Weigand A, Chen R, Wang J, Proust-Lima C, Mayeda ER. Approaches to Timescale Choice in Cognitive Aging Research and Potential Implications for Estimated Exposure Effects: Coordinated Analyses in 10 Cohorts of Older Adults. Epidemiology. 2025 Jul 01; 36(4):560-571.View Related Profiles.

Weuve, Jennifer
Mez, Jesse
Kezios, Katrina
Sims, Kendra
Hwang, Phillip
Chen, Ruijia

PMID: 40164562; PMCID: PMC12211680; DOI: 10.1097/EDE.0000000000001859;

Eisenberg-Guyot J, Kezios KL, Prins SJ, Schwartz S. Inconsistent consistency: evaluating the well-defined intervention assumption in applied epidemiological research. Int J Epidemiol. 2025 Feb 16; 54(2). PMID: 40037557; PMCID: PMC12225681; DOI: 10.1093/ije/dyaf015;

Kezios KL, Colvin CL, Grasset L, Duarte CD, Glymour MM, Zeki Al Hazzouri A. 20-Year income volatility and cognitive function in the National Longitudinal Survey of Youth (1979) cohort: A replication and extension of CARDIA findings. Soc Sci Med. 2025 Mar; 368:117798.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 39929027; PMCID: PMC11884999; DOI: 10.1016/j.socscimed.2025.117798;

Suglia SF, Shelton RC, Factor-Litvak P, Kezios K, Batayeh B, Cirillo P, Cohn B, Link B. Stress across the lifecourse and adult mental and physical health outcomes. Ann Behav Med. 2025 Jan 04; 59(1). PMID: 39921340

Swift SL, O'Donnell L, Horn B, Kezios K, Elfassy T, Reagan J, Zeki Al Hazzouri A, Collins T. State adoption of paid sick leave and cardiovascular disease mortality among adults in the United States, 2008-2019. J Public Health Policy. 2025 Mar; 46(1):53-70. PMID: 39521927

Kezios KL, Glymour MM, Zeki Al Hazzouri A. An Introduction to Longitudinal Synthetic Cohorts for Studying the Life Course Drivers of Health Outcomes and Inequalities in Older Age. Curr Epidemiol Rep. 2025 Dec; 12(1).View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 40756777; PMCID: PMC12316055; DOI: 10.1007/s40471-024-00355-1;

Jawadekar N, Zimmerman S, Lu P, Riley AR, Glymour MM, Kezios K, Al Hazzouri AZ. A critique and examination of the polysocial risk score approach: predicting cognition in the Health and Retirement Study. Am J Epidemiol. 2024 Sep 03; 193(9):1296-1300.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 38775285; PMCID: PMC11369218; DOI: 10.1093/aje/kwae074;

Kezios KL, Zimmerman SC, Buto PT, Rudolph KE, Calonico S, Zeki Al Hazzouri A, Glymour MM. Overcoming Data Gaps in Life Course Epidemiology by Matching Across Cohorts. Epidemiology. 2024 Sep 01; 35(5):610-617.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 38967975; PMCID: PMC11305898; DOI: 10.1097/EDE.0000000000001761;

Mesa R, Llabre M, Lee D, Rundek T, Kezios K, Hazzouri AZA, Elfassy T. Social Determinants of Health and Biological Age among Diverse U.S. Adults, NHANES 2011-2018. Res Sq. 2024 Jun 24. PMID: 38978574; PMCID: PMC11230476; DOI: 10.21203/rs.3.rs-4540892/v1;

Chen J, Moubadder L, Clausing ES, Kezios KL, Conneely KN, Hüls A, Baccarelli A, Factor-Litvak P, Cirrillo P, Shelton RC, Link BG, Suglia SF. Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife. Aging (Albany NY). 2024 Jun 13; 16(11):9350-9368. PMID: 38874516; PMCID: PMC11210249; DOI: 10.18632/aging.205943;

Calonico S, Jawadekar N, Kezios K, Zeki Al Hazzouri A. Regression discontinuity design studies: a guide for health researchers. BMJ. 2024 Feb 27; 384:e072254. PMID: 38413162

Kezios K, Hayes-Larson E. Sufficient component cause simulations: an underutilized epidemiologic teaching tool. Front Epidemiol. 2023; 3. PMID: 38435670; PMCID: PMC10906966; DOI: 10.3389/fepid.2023.1282809;

Jawadekar N, Kezios K, Odden MC, Stingone JA, Calonico S, Rudolph K, Zeki Al Hazzouri A. Practical Guide to Honest Causal Forests for Identifying Heterogeneous Treatment Effects. Am J Epidemiol. 2023 Jul 07; 192(7):1155-1165. PMID: 36843042

Lu P, Kezios K, Jawadekar N, Swift S, Vable A, Zeki Al Hazzouri A. Associations of Food Insecurity and Memory Function Among Middle to Older-Aged Adults in the Health and Retirement Study. JAMA Netw Open. 2023 Jul 03; 6(7):e2321474. PMID: 37399013; PMCID: PMC10318471; DOI: 10.1001/jamanetworkopen.2023.21474;

Kezios KL, Zimmerman SC, Zhang A, Calonico S, Jawadekar N, Glymour MM, Zeki Al Hazzouri A. Propensity Scores in Health Disparities Research: The Example of Cognitive Aging and the Hispanic Paradox. Epidemiology. 2023 Jul 01; 34(4):495-504.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 36976729; PMCID: PMC11304344; DOI: 10.1097/EDE.0000000000001620;

Nelson IS, Kezios K, Elbejjani M, Lu P, Yaffe K, Zeki Al Hazzouri A. Associations of Religious Service Attendance With Cognitive Function in Midlife: Findings From The CARDIA Study. J Gerontol B Psychol Sci Soc Sci. 2023 Apr 01; 78(4):684-694. PMID: 36239456; PMCID: PMC10413813; DOI: 10.1093/geronb/gbac165;

Lu P, Kezios K, Yaffe K, Kim S, Zhang A, Milazzo FH, Zeki Al Hazzouri A. Depressive symptoms mediate the relationship between sustained food insecurity and cognition: a causal mediation analysis. Ann Epidemiol. 2023 May; 81:6-13.e1. PMID: 36822280

Kezios KL, Lu P, Calonico S, Al Hazzouri AZ. History of Low Hourly Wage and All-Cause Mortality Among Middle-aged Workers. JAMA. 2023 Feb 21; 329(7):561-573. PMID: 36809322; PMCID: PMC9945122; DOI: 10.1001/jama.2023.0367;

Lu P, Kezios K, Milazzo F, Jawadekar N, Shelley M, Zeki Al Hazzouri A. Racial Differences in Employment and Poverty Histories and Health in Older Age. Am J Prev Med. 2023 Apr; 64(4):543-551. PMID: 36642644

Kezios KL, Zhang A, Kim S, Lu P, Glymour MM, Elfassy T, Al Hazzouri AZ. Association of Low Hourly Wages in Middle Age With Faster Memory Decline in Older Age: Evidence From the Health and Retirement Study. Am J Epidemiol. 2022 Nov 19; 191(12):2051-2062.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 36131387

Lu P, Kezios K, Lee J, Calonico S, Wimer C, Zeki Al Hazzouri A. Association Between Supplemental Nutrition Assistance Program Use and Memory Decline: Findings From the Health and Retirement Study. Neurology. 2023 Feb 07; 100(6):e595-e602. PMID: 36351816; PMCID: PMC9946186; DOI: 10.1212/WNL.0000000000201499;

Zeki Al Hazzouri A, Jawadekar N, Grasset L, Kaiser P, Kezios K, Calonico S, Glymour M, Hirsch C, Arnold AM, Varadhan R, Odden MC. Statins and Cognitive Decline in the Cardiovascular Health Study: A Comparison of Different Analytical Approaches. J Gerontol A Biol Sci Med Sci. 2022 May 05; 77(5):994-1001.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 34331536; PMCID: PMC9071443; DOI: 10.1093/gerona/glab220;

Zeki Al Hazzouri A, Jawadekar N, Kezios K, Caunca MR, Elfassy T, Calonico S, Kershaw KN, Yaffe K, Launer L, Elbejjani M, Grasset L, Manly J, Odden MC, Glymour MM. Racial Residential Segregation in Young Adulthood and Brain Integrity in Middle Age: Can We Learn From Small Samples? Am J Epidemiol. 2022 Mar 24; 191(4):591-598.View Related Profiles.

Kezios, Katrina
Glymour, Maria

PMID: 35020781; PMCID: PMC9430446; DOI: 10.1093/aje/kwab297;

Kezios KL, Suglia SF, Doyle DM, Susser E, Bradwin G, Cirillo P, Cohn B, Link B, Factor-Litvak P. Comparing different operationalizations of allostatic load measured in mid-life and their patterning by race and cumulative life course socioeconomic status. Psychoneuroendocrinology. 2022 May; 139:105689. PMID: 35202971

Kezios KL. Is the Way Forward to Step Back? Documenting the Frequency With Which Study Goals Are Misaligned With Study Methods and Interpretations in the Epidemiologic Literature. Epidemiol Rev. 2022 Jan 14; 43(1):4-18. PMID: 34535799

Siegel EL, Kezios KL, Houghton L, Pereira-Eshraghi C, Cirillo P, Cohn BA, Factor-Litvak P. Could maternal thyroid function during pregnancy affect daughters' age at menarche through child growth? A mediation analysis. Reprod Toxicol. 2022 Jan; 107:33-39. PMID: 34808459

Pamplin JR, Kezios KL, Hayes-Larson E, Keyes KM, Susser ES, Factor-Litvak P, Link BG, Bates LM. Response to: "Theory and empiricism: A comment on 'Interrogating the environmental affordances model' by Pamplin and colleagues". Soc Sci Med. 2021 Oct; 287:114368. PMID: 34534778

Pamplin JR, Kezios KL, Hayes-Larson E, Keyes KM, Susser ES, Factor-Litvak P, Link BG, Bates LM. Explaining the Black-white depression paradox: Interrogating the Environmental Affordances Model. Soc Sci Med. 2021 May; 277:113869. PMID: 33892418

Rundle AG, Factor-Litvak P, Suglia SF, Susser ES, Kezios KL, Lovasi GS, Cirillo PM, Cohn BA, Link BG. Tracking of Obesity in Childhood into Adulthood: Effects on Body Mass Index and Fat Mass Index at Age 50. Child Obes. 2020 Apr; 16(3):226-233. PMID: 32191541

Hayes-Larson E, Kezios KL, Mooney SJ, Lovasi G. Who is in this study, anyway? Guidelines for a useful Table 1. J Clin Epidemiol. 2019 Oct; 114:125-132. PMID: 31229583

Agha G, Kezios K, Baccarelli AA, DuBois Bowman F, Rauh V, Susser ES, Cohn B, Cirillo P, Link BG, Factor-Litvak P, Staudinger UM. Cognition level and change in cognition during adolescence are associated with cognition in midlife. Ann Epidemiol. 2019 Jul; 35:48-52.e2. PMID: 31060895

Rundle AG, Suglia SF, Susser ES, Factor-Litvak P, March D, Kezios KL, Lovasi GS, Fader KM, Andrews H, Cirillo PM, Cohn BA, Link BG. Body mass index across the life course: emergence of race-by-sex disparities in early childhood. Ann Epidemiol. 2019 May; 33:44-48. PMID: 30961991

Kezios KL, Hayes-Larson E. A Clarification on Causal Questions: We Ask Them More Often Than We Realize. Am J Public Health. 2018 Aug; 108(8):e4. PMID: 29995464

Widen EM, Kahn LG, Cirillo P, Cohn B, Kezios KL, Factor-Litvak P. Prepregnancy overweight and obesity are associated with impaired child neurodevelopment. Matern Child Nutr. 2018 Jan; 14(1). PMID: 28635158

Kezios K, Gu Y, Liu X, Cirillo P, Tarrant D, Petreas M, Park JS, Cohn B, Factor-Litvak P. Hydroxylated polychlorinated biphenyl metabolites (OH-PCBs), maternal smoking and size at birth. Reprod Toxicol. 2017 Aug; 71:166-175. PMID: 28314564

Link BG, Susser ES, Factor-Litvak P, March D, Kezios KL, Lovasi GS, Rundle AG, Suglia SF, Fader KM, Andrews HF, Johnson E, Cirillo PM, Cohn BA. Disparities in self-rated health across generations and through the life course. Soc Sci Med. 2017 Feb; 174:17-25. PMID: 27987434

Factor-Litvak P, Susser E, Kezios K, McKeague I, Kark JD, Hoffman M, Kimura M, Wapner R, Aviv A. Leukocyte Telomere Length in Newborns: Implications for the Role of Telomeres in Human Disease. Pediatrics. 2016 Apr; 137(4). PMID: 26969272

Kezios KL, Liu X, Cirillo PM, Cohn BA, Kalantzi OI, Wang Y, Petreas MX, Park JS, Factor-Litvak P. Dichlorodiphenyltrichloroethane (DDT), DDT metabolites and pregnancy outcomes. Reprod Toxicol. 2013 Jan; 35:156-64. PMID: 23142753

Kezios KL, Liu X, Cirillio PM, Kalantzi OI, Wang Y, Petreas MX, Park JS, Bradwin G, Cohn BA, Factor-Litvak P. Prenatal polychlorinated biphenyl exposure is associated with decreased gestational length but not birth weight: archived samples from the Child Health and Development Studies pregnancy cohort. Environ Health. 2012 Jul 20; 11:49. PMID: 22817616

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 52 publications over 11 distinct years, with a maximum of 17 publications in 2025

Bar chart showing 52 publications over 11 distinct years, with a maximum of 17 publications in 2025

Year	Publications
2012	2
2016	2
2017	2
2018	1
2019	3
2020	1
2021	3
2022	6
2023	8
2024	7
2025	17

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Life Course Epidemiology
Epidemiologic Methods
Causal Inference
Meta-research
Cognitive Aging
Social Determinants of Health

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