Kathleen Morgan | Profiles RNS

Kathleen Morgan, PhD

Professor

Boston University College of Health & Rehabilitation Sciences: Sargent College

Health Sciences

PhD, University of Cincinnati
BS, College of Mount St. Joseph

Websites

	Cytoskeleton & Signaling Laboratory
	Sargent College Faculty
	ResearchGate
	Public Relations - BU Experts

ORCID : 0000-0003-3300-3630

Scholarly interests include: the interactions between signaling proteins and cytoskeletal proteins; the differentiated smooth muscle cell; mechanisms of trafficking of signaling molecules; stroke, hypertension, vascular dementia and pre-term labor.

The Morgan lab works on the intersection of signaling pathways with the cytoskeleton of the contractile vascular smooth muscle cell. We have demonstrated that the nonmuscle cortical cytoskeleton and the adhesion plaques attached to it undergo dynamic rearrangements during stimulus-induced alterations in vascular tone and that this is one factor that regulates vascular contractility and compliance.

Recently we have become especially interested in the possible role of the vascular cytoskeleton, and its connection to matrix proteins through integrins, in the determination of known aging-associated increases aortic stiffness. Aging-associated aortic stiffness is known to be an independent and early predictor for adverse cardiovascular outcomes. We are currently testing the idea that cytoskeletal protein interactions may offer novel therapeutic targets for the regulation of aortic stiffness, and, as a consequence, vascular dementia.

As a result of the fact that fully differentiated vascular smooth muscle cells are not readily transfectable we have developed a number of special techniques/reagents that may be of use to others. For example, we have designed and used a number of dominant negative, cell permeant, peptide constructs and we have developed morpholino approaches to knocking down smooth muscle proteins in organ culture.

Member
Boston University
Whitaker Cardiovascular Institute

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Director
Boston University College of Health & Rehabilitation Sciences: Sargent College
Cytoskeleton & Signaling Lab

Dean ad interim (previously held: 6/2013 – 8/2014)
Boston University College of Health & Rehabilitation Sciences: Sargent College

Chair (previously held: 10/2006 - 8/2015)
Boston University College of Health & Rehabilitation Sciences: Sargent College
Health Sciences

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease
09/01/2017 - 05/31/2024 (PI)
NIH/National Institute on Aging
5R01AG053274-05

Role of Smooth Muscle Calponin in Vascular Pathobiology
11/01/2019 - 10/31/2022 (Subcontract PI)
Augusta University Research Institute Inc NIH NHLBI
5R01HL136224-04

Role of Smooth Muscle Calponin in Vascular Pathoglology/URF AWD 00002824
12/15/2018 - 10/31/2022 (Subcontract PI)
University of Rochester NIH NHLBI
1R01HL136224-01A1

The Role of the Cytoskeleton in Vascular Aging
09/01/2015 - 10/31/2017 (PI)
NIH/National Institute on Aging
5R21AG050599-02

Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease
09/15/2016 - 08/31/2017 (PI)
NIH/National Institute on Aging
1R56AG053274-01

DYNAMICS OF THE VASCULAR SMOOTH MUSCLE CYTOSKELETON
07/01/2007 - 06/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5P01HL086655-05

Title

Yr	Title	Project-Sub Proj	Pubs
2021	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	5R01AG053274-05
2020	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	5R01AG053274-04
2019	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	3R01AG053274-03S1
2019	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	5R01AG053274-03
2018	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	5R01AG053274-02
2017	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	1R01AG053274-01A1
2016	Actin and focal adhesion remodeling as therapeutic targets in cardiovascular disease	1R56AG053274-01
2016	The Role of the Cytoskeleton in Vascular Aging	5R21AG050599-02
2015	The Role of the Cytoskeleton in Vascular Aging	1R21AG050599-01
2011	Dynamics of the Vascular Smooth Muscle Cytoskeleton	5P01HL086655-05	69

Showing 10 of 67 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Kajuluri LP, Lyu QR, Doja J, Kumar A, Wilson MP, Sgrizzi SR, Rezaeimanesh E, Miano JM, Morgan KG. Calponin 1 inhibits agonist-induced ERK activation and decreases calcium sensitization in vascular smooth muscle. J Cell Mol Med. 2024 Jan; 28(1):e18025. PMID: 38147352; PMCID: PMC10805486; DOI: 10.1111/jcmm.18025;

Kaplan KM, Morgan KG. The importance of dystrophin and the dystrophin associated proteins in vascular smooth muscle. Front Physiol. 2022; 13:1059021. PMID: 36505053; PMCID: PMC9732661; DOI: 10.3389/fphys.2022.1059021;

Suphamungmee W, Lehman W, Morgan KG. Functional Remodeling of the Contractile Smooth Muscle Cell Cortex, a Provocative Concept, Supported by Direct Visualization of Cortical Remodeling. Biology (Basel). 2022 Apr 26; 11(5).View Related Profiles.

Morgan, Kathleen
Lehman, William
Suphamungmee, Worawit

PMID: 35625390; PMCID: PMC9138025; DOI: 10.3390/biology11050662;

Nicholson CJ, Xing Y, Lee S, Liang S, Mohan S, O'Rourke C, Kang J, Morgan KG. Ageing causes an aortic contractile dysfunction phenotype by targeting the expression of members of the extracellular signal-regulated kinase pathway. J Cell Mol Med. 2022 03; 26(5):1456-1465. PMID: 35181997; PMCID: PMC8899171; DOI: 10.1111/jcmm.17118;

Kajuluri LP, Singh K, Morgan KG. Vascular aging, the vascular cytoskeleton and aortic stiffness. Explor Med. 2021; 2:186-197. PMID: 34414394; PMCID: PMC8372409; DOI: 10.37349/emed.2021.00041;

Singh K, Kim AB, Morgan KG. Non-muscle myosin II regulates aortic stiffness through effects on specific focal adhesion proteins and the non-muscle cortical cytoskeleton. J Cell Mol Med. 2021 03; 25(5):2471-2483. PMID: 33547870; PMCID: PMC7933926; DOI: 10.1111/jcmm.16170;

Valisno JAC, May J, Singh K, Helm EY, Venegas L, Budbazar E, Goodman JB, Nicholson CJ, Avram D, Cohen RA, Mitchell GF, Morgan KG, Seta F. BCL11B Regulates Arterial Stiffness and Related Target Organ Damage. Circ Res. 2021 03 19; 128(6):755-768.View Related Profiles.

Seta, Francesca
Goodman, Jena
May, Joel
Morgan, Kathleen
Cohen, Richard

PMID: 33530702; PMCID: PMC7969164; DOI: 10.1161/CIRCRESAHA.120.316666;

Wang Y, Taylor E, Zikopoulos B, Seta F, Huang N, Hamilton JA, Kantak KM, Morgan KG. Aging-induced microbleeds of the mouse thalamus compared to sensorimotor and memory defects. Neurobiol Aging. 2021 04; 100:39-47.View Related Profiles.

Taylor, Erik
Seta, Francesca
Hamilton, James
Kantak, Kathleen
Morgan, Kathleen

PMID: 33477010; PMCID: PMC8162167; DOI: 10.1016/j.neurobiolaging.2020.11.017;

Taylor EN, Huang N, Wisco J, Wang Y, Morgan KG, Hamilton JA. The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds. J Transl Med. 2020 07 08; 18(1):277.View Related Profiles.

Hamilton, James
Wisco, Jonathan
Morgan, Kathleen

PMID: 32641073; PMCID: PMC7346388; DOI: 10.1186/s12967-020-02441-6;

Nicholson CJ, Singh K, Saphirstein RJ, Gao YZ, Li Q, Chiu JG, Leavis P, Verwoert GC, Mitchell GF, Porter T, Morgan KG. Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces. J Am Heart Assoc. 2018 07 18; 7(15).View Related Profiles.

Morgan, Kathleen
Porter, Tyrone

PMID: 30021807; PMCID: PMC6201469; DOI: 10.1161/JAHA.118.008926;

Showing 10 of 185 results. Show More

Vetterkind S, Lin QQ, Morgan KG. A novel mechanism of ERK1/2 regulation in smooth muscle involving acetylation of the ERK1/2 scaffold IQGAP1. Sci Rep. 2017 08 24; 7(1):9302. PMID: 28839270; PMCID: PMC5571205; DOI: 10.1038/s41598-017-09434-4;

Nicholson CJ, Seta F, Lee S, Morgan KG. MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways. J Cell Mol Med. 2017 Jan; 21(1):81-95.View Related Profiles.

Seta, Francesca
Morgan, Kathleen

PMID: 27502584; PMCID: PMC5192880; DOI: 10.1111/jcmm.12940;

Brozovich FV, Nicholson CJ, Degen CV, Gao YZ, Aggarwal M, Morgan KG. Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders. Pharmacol Rev. 2016 Apr; 68(2):476-532. PMID: 27037223; PMCID: PMC4819215; DOI: 10.1124/pr.115.010652;

Fry JL, Shiraishi Y, Turcotte R, Yu X, Gao YZ, Akiki R, Bachschmid M, Zhang Y, Morgan KG, Cohen RA, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension. J Am Heart Assoc. 2015 Sep; 4(9):e002384.View Related Profiles.

Seta, Francesca
Fry, Jessica
Morgan, Kathleen
Bachschmid, Markus
Cohen, Richard

PMID: 26376991; PMCID: PMC4599512; DOI: 10.1161/JAHA.115.002384;

Saphirstein RJ, Gao YZ, Lin QQ, Morgan KG. Cortical actin regulation modulates vascular contractility and compliance in veins. J Physiol. 2015 Sep 1; 593(17):3929-41. PMID: 26096914; PMCID: PMC4575578; DOI: 10.1113/JP270845;

Gao YZ, Saphirstein RJ, Yamin R, Suki B, Morgan KG. Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function? Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1252-61.View Related Profiles.

Suki, Bela
Morgan, Kathleen

PMID: 25128168; PMCID: PMC4200340; DOI: 10.1152/ajpheart.00392.2014;

Saphirstein RJ, Morgan KG. The contribution of vascular smooth muscle to aortic stiffness across length scales. Microcirculation. 2014 Apr; 21(3):201-7. PMID: 24635219; DOI: 10.1111/micc.12101;

Jensen MH, Morris EJ, Gallant CM, Morgan KG, Weitz DA, Moore JR. Mechanism of calponin stabilization of cross-linked actin networks. Biophys J. 2014 Feb 18; 106(4):793-800.View Related Profiles.

Moore, Jeffrey
Morgan, Kathleen

PMID: 24559982; PMCID: PMC3944828; DOI: 10.1016/j.bpj.2013.12.042;

Kim HR, Gallant C, Morgan KG. Regulation of PKC autophosphorylation by calponin in contractile vascular smooth muscle tissue. Biomed Res Int. 2013; 2013:358643. PMID: 24350264; PMCID: PMC3852320; DOI: 10.1155/2013/358643;

Morgan KG. The importance of the smooth muscle cytoskeleton to preterm labour. Exp Physiol. 2014 Mar; 99(3):525-9. PMID: 24121284; DOI: 10.1113/expphysiol.2013.072876;

Vetterkind S, Poythress RH, Lin QQ, Morgan KG. Hierarchical scaffolding of an ERK1/2 activation pathway. Cell Commun Signal. 2013; 11:65. PMID: 23987506; PMCID: PMC3846746; DOI: 10.1186/1478-811X-11-65;

Poythress RH, Gallant C, Vetterkind S, Morgan KG. Vasoconstrictor-induced endocytic recycling regulates focal adhesion protein localization and function in vascular smooth muscle. Am J Physiol Cell Physiol. 2013 Jul 15; 305(2):C215-27. PMID: 23703522; PMCID: PMC3725623; DOI: 10.1152/ajpcell.00103.2013;

Saphirstein RJ, Gao YZ, Jensen MH, Gallant CM, Vetterkind S, Moore JR, Morgan KG. The focal adhesion: a regulated component of aortic stiffness. PLoS One. 2013; 8(4):e62461.View Related Profiles.

Moore, Jeffrey
Morgan, Kathleen

PMID: 23626821; PMCID: PMC3633884; DOI: 10.1371/journal.pone.0062461;

Yilmaz M, Gangopadhyay SS, Leavis P, Grabarek Z, Morgan KG. Phosphorylation at Ser²6 in the ATP-binding site of Ca²?/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity. Biosci Rep. 2013; 33(2). PMID: 23289753; PMCID: PMC3566533; DOI: 10.1042/BSR20120116;

Kang YH, Yang IJ, Morgan KG, Shin HM. Cinnamyl alcohol attenuates vasoconstriction by activation of K? channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase. Exp Mol Med. 2012 Dec 31; 44(12):749-55. PMID: 23178275; PMCID: PMC3538982; DOI: 10.3858/emm.2012.44.12.083;

Min J, Reznichenko M, Poythress RH, Gallant CM, Vetterkind S, Li Y, Morgan KG. Src modulates contractile vascular smooth muscle function via regulation of focal adhesions. J Cell Physiol. 2012 Nov; 227(11):3585-92. PMID: 22287273; PMCID: PMC3348426; DOI: 10.1002/jcp.24062;

Baranwal S, Naydenov NG, Harris G, Dugina V, Morgan KG, Chaponnier C, Ivanov AI. Nonredundant roles of cytoplasmic ß- and ?-actin isoforms in regulation of epithelial apical junctions. Mol Biol Cell. 2012 Sep; 23(18):3542-53. PMID: 22855531; PMCID: PMC3442403; DOI: 10.1091/mbc.E12-02-0162;

Yamin R, Morgan KG. Deciphering actin cytoskeletal function in the contractile vascular smooth muscle cell. J Physiol. 2012 Sep 1; 590(Pt 17):4145-54. PMID: 22687615; PMCID: PMC3473273; DOI: 10.1113/jphysiol.2012.232306;

Vetterkind S, Saphirstein RJ, Morgan KG. Stimulus-specific activation and actin dependency of distinct, spatially separated ERK1/2 fractions in A7r5 smooth muscle cells. PLoS One. 2012; 7(2):e30409. PMID: 22363435; PMCID: PMC3283592; DOI: 10.1371/journal.pone.0030409;

Lehman W, Morgan KG. Structure and dynamics of the actin-based smooth muscle contractile and cytoskeletal apparatus. J Muscle Res Cell Motil. 2012 Dec; 33(6):461-9.View Related Profiles.

Morgan, Kathleen
Lehman, William

PMID: 22311558; PMCID: PMC3394904; DOI: 10.1007/s10974-012-9283-z;

Vetterkind S, Morgan KG. Muscle; Fundamental biology and mechanisms of disease. Eds Hill JA and Olson EN. Regulation of smooth muscle contractions. Elsevier. Amsterdam. 2012; 1:1173-1182.

Jensen MH, Watt J, Hodgkinson JL, Gallant C, Appel S, El-Mezgueldi M, Angelini TE, Morgan KG, Lehman W, Moore JR. Effects of basic calponin on the flexural mechanics and stability of F-actin. Cytoskeleton (Hoboken). 2012 Jan; 69(1):49-58.View Related Profiles.

Moore, Jeffrey
Morgan, Kathleen
Lehman, William

PMID: 22135101; PMCID: PMC3355516; DOI: 10.1002/cm.20548;

Cho YE, Ahn DS, Morgan KG, Lee YH. Enhanced contractility and myosin phosphorylation induced by Ca(2+)-independent MLCK activity in hypertensive rats. Cardiovasc Res. 2011 Jul 1; 91(1):162-70. PMID: 21378385; PMCID: PMC3112018; DOI: 10.1093/cvr/cvr043;

Gallant C, Appel S, Graceffa P, Leavis P, Lin JJ, Gunning PW, Schevzov G, Chaponnier C, DeGnore J, Lehman W, Morgan KG. Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells. Am J Physiol Cell Physiol. 2011 Jun; 300(6):C1356-65.View Related Profiles.

Morgan, Kathleen
Lehman, William

PMID: 21289288; PMCID: PMC3118631; DOI: 10.1152/ajpcell.00450.2010;

Kim HR, Leavis PC, Graceffa P, Gallant C, Morgan KG. A new method for direct detection of the sites of actin polymerization in intact cells and its application to differentiated vascular smooth muscle. Am J Physiol Cell Physiol. 2010 Nov; 299(5):C988-93. PMID: 20686075; PMCID: PMC2980300; DOI: 10.1152/ajpcell.00210.2010;

Appel S, Morgan KG. Scaffolding proteins and non-proliferative functions of ERK1/2. Commun Integr Biol. 2010 Jul; 3(4):354-6. PMID: 20798825; PMCID: PMC2928317; DOI: 10.4161/cib.3.4.11832;

Appel S, Allen PG, Vetterkind S, Jin JP, Morgan KG. h3/Acidic calponin: an actin-binding protein that controls extracellular signal-regulated kinase 1/2 activity in nonmuscle cells. Mol Biol Cell. 2010 Apr 15; 21(8):1409-22. PMID: 20181831; PMCID: PMC2854098; DOI: 10.1091/mbc.E09-06-0451;

Vetterkind S, Lee E, Sundberg E, Poythress RH, Tao TC, Preuss U, Morgan KG. Par-4: a new activator of myosin phosphatase. Mol Biol Cell. 2010 Apr 1; 21(7):1214-24. PMID: 20130087; PMCID: PMC2847525; DOI: 10.1091/mbc.E09-08-0711;

Kim HR, Graceffa P, Ferron F, Gallant C, Boczkowska M, Dominguez R, Morgan KG. Actin polymerization in differentiated vascular smooth muscle cells requires vasodilator-stimulated phosphoprotein. Am J Physiol Cell Physiol. 2010 Mar; 298(3):C559-71. PMID: 20018948; PMCID: PMC2838578; DOI: 10.1152/ajpcell.00431.2009;

Li Y, Reznichenko M, Tribe RM, Hess PE, Taggart M, Kim H, DeGnore JP, Gangopadhyay S, Morgan KG. Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling. PLoS One. 2009; 4(10):e7489. PMID: 19834610; PMCID: PMC2759504; DOI: 10.1371/journal.pone.0007489;

Gangopadhyay SS, Kengni E, Appel S, Gallant C, Kim HR, Leavis P, DeGnore J, Morgan KG. Smooth muscle archvillin is an ERK scaffolding protein. J Biol Chem. 2009 Jun 26; 284(26):17607-15. PMID: 19406750; PMCID: PMC2719399; DOI: 10.1074/jbc.M109.002386;

Morgan KG. Contractility in health and disease. J Cell Mol Med. 2008 Dec; 12(6A):2157. PMID: 19120699; PMCID: PMC4514095; DOI: 10.1111/j.1582-4934.2008.00565.x;

Kim HR, Appel S, Vetterkind S, Gangopadhyay SS, Morgan KG. Smooth muscle signalling pathways in health and disease. J Cell Mol Med. 2008 Dec; 12(6A):2165-80. PMID: 19120701; PMCID: PMC2692531; DOI: 10.1111/j.1582-4934.2008.00552.x;

Kim HR, Gallant C, Leavis PC, Gunst SJ, Morgan KG. Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent. Am J Physiol Cell Physiol. 2008 Sep; 295(3):C768-78. PMID: 18596213; PMCID: PMC2544444; DOI: 10.1152/ajpcell.00174.2008;

Gangopadhyay SS, Gallant C, Sundberg EJ, Lane WS, Morgan KG. Regulation of Ca2+/calmodulin kinase II by a small C-terminal domain phosphatase. Biochem J. 2008 Jun 15; 412(3):507-16. PMID: 18338982; PMCID: PMC2724867; DOI: 10.1042/BJ20071582;

Vetterkind S, Morgan KG. The pro-apoptotic protein Par-4 facilitates vascular contractility by cytoskeletal targeting of ZIPK. J Cell Mol Med. 2009 May; 13(5):887-95. PMID: 18505470; PMCID: PMC2700217; DOI: 10.1111/j.1582-4934.2008.00374.x;

Wu X, Morgan KG, Jones CJ, Tribe RM, Taggart MJ. Myometrial mechanoadaptation during pregnancy: implications for smooth muscle plasticity and remodelling. J Cell Mol Med. 2008 Aug; 12(4):1360-73. PMID: 18363833; PMCID: PMC2729593; DOI: 10.1111/j.1582-4934.2008.00306.x;

Munevar S, Gangopadhyay SS, Gallant C, Colombo B, Sellke FW, Morgan KG. CaMKIIT287 and T305 regulate history-dependent increases in alpha agonist-induced vascular tone. J Cell Mol Med. 2008 Jan-Feb; 12(1):219-26. PMID: 18088385; PMCID: PMC3823483; DOI: 10.1111/j.1582-4934.2007.00202.x;

Taggart MJ, Morgan KG. Regulation of the uterine contractile apparatus and cytoskeleton. Semin Cell Dev Biol. 2007 Jun; 18(3):296-304. PMID: 17582796; PMCID: PMC2001260; DOI: 10.1016/j.semcdb.2007.05.006;

Ahn DS, Choi SK, Kim YH, Cho YE, Shin HM, Morgan KG, Lee YH. Enhanced stretch-induced myogenic tone in the basilar artery of spontaneously hypertensive rats. J Vasc Res. 2007; 44(3):182-91. PMID: 17337904; DOI: 10.1159/000100374;

Li Y, Gallant C, Malek S, Morgan KG. Focal adhesion signaling is required for myometrial ERK activation and contractile phenotype switch before labor. J Cell Biochem. 2007 Jan 1; 100(1):129-40. PMID: 16888778; DOI: 10.1002/jcb.21033;

Deng L, Trepat X, Butler JP, Millet E, Morgan KG, Weitz DA, Fredberg JJ. Fast and slow dynamics of the cytoskeleton. Nat Mater. 2006 Aug; 5(8):636-40. PMID: 16845421; DOI: 10.1038/nmat1685;

Ryu SK, Ahn DS, Cho YE, Choi SK, Kim YH, Morgan KG, Lee YH. Augmented sphingosylphosphorylcholine-induced Ca2+-sensitization of mesenteric artery contraction in spontaneously hypertensive rat. Naunyn Schmiedebergs Arch Pharmacol. 2006 Apr; 373(1):30-6. PMID: 16521007; DOI: 10.1007/s00210-006-0036-7;

Jang GJ, Ahn DS, Cho YE, Morgan KG, Lee YH. C2-ceramide induces vasodilation in phenylephrine-induced pre-contracted rat thoracic aorta: role of RhoA/Rho-kinase and intracellular Ca2+ concentration. Naunyn Schmiedebergs Arch Pharmacol. 2005 Nov; 372(3):242-50. PMID: 16231160; DOI: 10.1007/s00210-005-0008-3;

Marganski WA, Gangopadhyay SS, Je HD, Gallant C, Morgan KG. Targeting of a novel Ca+2/calmodulin-dependent protein kinase II is essential for extracellular signal-regulated kinase-mediated signaling in differentiated smooth muscle cells. Circ Res. 2005 Sep 16; 97(6):541-9. PMID: 16109919; DOI: 10.1161/01.RES.0000182630.29093.0d;

Gallant C, You JY, Sasaki Y, Grabarek Z, Morgan KG. MARCKS is a major PKC-dependent regulator of calmodulin targeting in smooth muscle. J Cell Sci. 2005 Aug 15; 118(Pt 16):3595-605. PMID: 16046479; DOI: 10.1242/jcs.02493;

Strachan GD, Morgan KL, Otis LL, Caltagarone J, Gittis A, Bowser R, Jordan-Sciutto KL. Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein. Biochemistry. 2004 Sep 28; 43(38):12113-22. PMID: 15379550; PMCID: PMC3670950

Gangopadhyay SS, Takizawa N, Gallant C, Barber AL, Je HD, Smith TC, Luna EJ, Morgan KG. Smooth muscle archvillin: a novel regulator of signaling and contractility in vascular smooth muscle. J Cell Sci. 2004 Oct 1; 117(Pt 21):5043-57. PMID: 15383618; DOI: 10.1242/jcs.01378;

Li Y, Je HD, Malek S, Morgan KG. Role of ERK1/2 in uterine contractility and preterm labor in rats. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R328-35. PMID: 15072963; DOI: 10.1152/ajpregu.00042.2004;

Shin HM, Morgan KG. Vasodilation by banhabackchulchunmatang, a Chinese medicine, is associated with negative modulation of PKCalpha activation and NO production. Life Sci. 2003 Dec 26; 74(6):723-32. PMID: 14654165

Je HD, Gallant C, Leavis PC, Morgan KG. Caveolin-1 regulates contractility in differentiated vascular smooth muscle. Am J Physiol Heart Circ Physiol. 2004 Jan; 286(1):H91-8. PMID: 12969891; DOI: 10.1152/ajpheart.00472.2003;

Wier WG, Morgan KG. Alpha1-adrenergic signaling mechanisms in contraction of resistance arteries. Rev Physiol Biochem Pharmacol. 2003; 150:91-139. PMID: 12884052; DOI: 10.1007/s10254-003-0019-8;

Gangopadhyay SS, Barber AL, Gallant C, Grabarek Z, Smith JL, Morgan KG. Differential functional properties of calmodulin-dependent protein kinase IIgamma variants isolated from smooth muscle. Biochem J. 2003 Jun 1; 372(Pt 2):347-57. PMID: 12603201; PMCID: PMC1223399; DOI: 10.1042/BJ20030015;

Li Y, Je HD, Malek S, Morgan KG. ERK1/2-mediated phosphorylation of myometrial caldesmon during pregnancy and labor. Am J Physiol Regul Integr Comp Physiol. 2003 Jan; 284(1):R192-9. PMID: 12388473

Shin HM, Je HD, Gallant C, Tao TC, Hartshorne DJ, Ito M, Morgan KG. Differential association and localization of myosin phosphatase subunits during agonist-induced signal transduction in smooth muscle. Circ Res. 2002 Mar 22; 90(5):546-53. PMID: 11909818

Yeon DS, Kim JS, Ahn DS, Kwon SC, Kang BS, Morgan KG, Lee YH. Role of protein kinase C- or RhoA-induced Ca(2+) sensitization in stretch-induced myogenic tone. Cardiovasc Res. 2002 Feb 1; 53(2):431-8. PMID: 11827694

Je HD, Gangopadhyay SS, Ashworth TD, Morgan KG. Calponin is required for agonist-induced signal transduction--evidence from an antisense approach in ferret smooth muscle. J Physiol. 2001 Dec 1; 537(Pt 2):567-77. PMID: 11731586; PMCID: PMC2278950

Morgan KG, Gangopadhyay SS. Invited review: cross-bridge regulation by thin filament-associated proteins. J Appl Physiol (1985). 2001 Aug; 91(2):953-62. PMID: 11457814

Morgan KG. Nonmuscle motility/cytoskeleton. Am J Physiol Cell Physiol. 2001 Jun; 280(6):C1634-5. PMID: 11350759

Lee YH, Hwang MK, Morgan KG, Taggart MJ. Receptor-coupled contractility of uterine smooth muscle: from membrane to myofilaments. Exp Physiol. 2001 Mar; 86(2):283-8. PMID: 11429645

Hulvershorn J, Gallant C, Wang CA, Dessy C, Morgan KG. Calmodulin levels are dynamically regulated in living vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2001 Mar; 280(3):H1422-6. PMID: 11179093

Leinweber B, Parissenti AM, Gallant C, Gangopadhyay SS, Kirwan-Rhude A, Leavis PC, Morgan KG. Regulation of protein kinase C by the cytoskeletal protein calponin. J Biol Chem. 2000 Dec 22; 275(51):40329-36. PMID: 11006297; DOI: 10.1074/jbc.M008257200;

Dessy C, Matsuda N, Hulvershorn J, Sougnez CL, Sellke FW, Morgan KG. Evidence for involvement of the PKC-alpha isoform in myogenic contractions of the coronary microcirculation. Am J Physiol Heart Circ Physiol. 2000 Sep; 279(3):H916-23. PMID: 10993750

Matsuda N, Morgan KG, Sellke FW. Effects of pinacidil on coronary Ca(2+)-myosin phosphorylation in cold potassium cardioplegia model. Am J Physiol Heart Circ Physiol. 2000 Sep; 279(3):H882-8. PMID: 10993746

Kim I, Je HD, Gallant C, Zhan Q, Riper DV, Badwey JA, Singer HA, Morgan KG. Ca2+-calmodulin-dependent protein kinase II-dependent activation of contractility in ferret aorta. J Physiol. 2000 Jul 15; 526 Pt 2:367-74. PMID: 10896725; PMCID: PMC2270028

Taggart MJ, Leavis P, Feron O, Morgan KG. Inhibition of PKCalpha and rhoA translocation in differentiated smooth muscle by a caveolin scaffolding domain peptide. Exp Cell Res. 2000 Jul 10; 258(1):72-81. PMID: 10912789; DOI: 10.1006/excr.2000.4891;

Lee YH, Gallant C, Guo H, Li Y, Wang CA, Morgan KG. Regulation of vascular smooth muscle tone by N-terminal region of caldesmon. Possible role of tethering actin to myosin. J Biol Chem. 2000 Feb 4; 275(5):3213-20. PMID: 10652307

Kim I, Leinweber BD, Morgalla M, Butler WE, Seto M, Sasaki Y, Peterson JW, Morgan KG. Thin and thick filament regulation of contractility in experimental cerebral vasospasm. Neurosurgery. 2000 Feb; 46(2):440-6; discussion 446-7. PMID: 10690734

Leinweber BD, Leavis PC, Grabarek Z, Wang CL, Morgan KG. Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins. Biochem J. 1999 Nov 15; 344 Pt 1:117-23. PMID: 10548541; PMCID: PMC1220621

Matsuda N, Morgan KG, Sellke FW. Preconditioning improves cardioplegia-related coronary microvascular smooth muscle hypercontractility: role of KATP channels. J Thorac Cardiovasc Surg. 1999 Sep; 118(3):438-45. PMID: 10469957

Taggart MJ, Lee YH, Morgan KG. Cellular redistribution of PKCalpha, rhoA, and ROKalpha following smooth muscle agonist stimulation. Exp Cell Res. 1999 Aug 25; 251(1):92-101. PMID: 10438574; DOI: 10.1006/excr.1999.4565;

Matsuda N, Tofukuji M, Morgan KG, Sellke FW. Influence of oxygenation on endothelial modulation of coronary vasomotor function during hyperkalemic cardioplegia. Surgery. 1999 Aug; 126(2):264-71. PMID: 10455893

Tofukuji M, Matsuda N, Dessy C, Morgan KG, Sellke FW. Intracellular free calcium accumulation in ferret vascular smooth muscle during crystalloid and blood cardioplegic infusions. J Thorac Cardiovasc Surg. 1999 Jul; 118(1):163-72. PMID: 10384199

Lee YH, Kim I, Laporte R, Walsh MP, Morgan KG. Isozyme-specific inhibitors of protein kinase C translocation: effects on contractility of single permeabilized vascular muscle cells of the ferret. J Physiol. 1999 Jun 15; 517 ( Pt 3):709-20. PMID: 10358112; PMCID: PMC2269363

Matsuda N, Tofukuji M, Morgan KG, Sellke FW. Coronary microvascular protection with mg2+: effects on intracellular calcium regulation and vascular function. Am J Physiol. 1999 Apr; 276(4 Pt 2):H1124-30. PMID: 10199833

Morgan KG, Kim I, Butler WE. Molecular Mechanisms of Smooth Muscle Contraction. Kohama K and Sasaki Y, eds. Thick and thin filament regulation of smooth muscle contraction in health and disease. R.G. Landes. Georgetown, TX. 1999; 81-96.

Morgan KG, Leinweber BD. PKC-dependent signalling mechanisms in differentiated smooth muscle. Acta Physiol Scand. 1998 Dec; 164(4):495-505. PMID: 9887972; DOI: 10.1046/j.1365-201X.1998.00445.x;

Dessy C, Kim I, Sougnez CL, Laporte R, Morgan KG. A role for MAP kinase in differentiated smooth muscle contraction evoked by alpha-adrenoceptor stimulation. Am J Physiol. 1998 Oct; 275(4 Pt 1):C1081-6. PMID: 9755061

Parker CA, Takahashi K, Tang JX, Tao T, Morgan KG. Cytoskeletal targeting of calponin in differentiated, contractile smooth muscle cells of the ferret. J Physiol. 1998 Apr 1; 508 ( Pt 1):187-98. PMID: 9490838; PMCID: PMC2230870

Tang S, Morgan KG, Parker C, Ware JA. Requirement for protein kinase C theta for cell cycle progression and formation of actin stress fibers and filopodia in vascular endothelial cells. J Biol Chem. 1997 Nov 7; 272(45):28704-11. PMID: 9353339

Menice CB, Hulvershorn J, Adam LP, Wang CA, Morgan KG. Calponin and mitogen-activated protein kinase signaling in differentiated vascular smooth muscle. J Biol Chem. 1997 Oct 3; 272(40):25157-61. PMID: 9312127

Rittenhouse AR, Parker C, Brugnara C, Morgan KG, Alper SL. Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole. Am J Physiol. 1997 Jul; 273(1 Pt 1):C45-56. PMID: 9252441

Tseng S, Kim R, Kim T, Morgan KG, Hai CM. F-actin disruption attenuates agonist-induced [Ca2+], myosin phosphorylation, and force in smooth muscle. Am J Physiol. 1997 Jun; 272(6 Pt 1):C1960-7. PMID: 9227425

Taggart MJ, Menice CB, Morgan KG, Wray S. Effect of metabolic inhibition on intracellular Ca2+, phosphorylation of myosin regulatory light chain and force in rat smooth muscle. J Physiol. 1997 Mar 1; 499 ( Pt 2):485-96. PMID: 9080376; PMCID: PMC1159321

Graceffa P, Adam LP, Morgan KG. Strong interaction between caldesmon and calponin. J Biol Chem. 1996 Nov 29; 271(48):30336-9. PMID: 8939993

Horowitz A, Menice CB, Laporte R, Morgan KG. Mechanisms of smooth muscle contraction. Physiol Rev. 1996 Oct; 76(4):967-1003. PMID: 8874491

Jain M, Dai HB, Carrozza JP, Sellke FW, Morgan KG. Intrinsic tone as potential vascular reserve in conductance and resistance vessels. Circulation. 1996 Sep 1; 94(5):1083-8.View Related Profiles.

Carrozza, Joseph
Morgan, Kathleen

PMID: 8790050

Horowitz A, Clément-Chomienne O, Walsh MP, Morgan KG. Epsilon-isoenzyme of protein kinase C induces a Ca(2+)-independent contraction in vascular smooth muscle. Am J Physiol. 1996 Aug; 271(2 Pt 1):C589-94. PMID: 8769999

Horowitz A, Clément-Chomienne O, Walsh MP, Tao T, Katsuyama H, Morgan KG. Effects of calponin on force generation by single smooth muscle cells. Am J Physiol. 1996 May; 270(5 Pt 2):H1858-63. PMID: 8928896

Bulter WE, Peterson JW, Zervas NT, Morgan KG. Intracellular calcium, myosin light chain phosphorylation, and contractile force in experimental cerebral vasospasm. Neurosurgery. 1996 Apr; 38(4):781-7; discussion 787-8. PMID: 8692399

Jahn L, Sadoshima J, Greene A, Parker C, Morgan KG, Izumo S. Conditional differentiation of heart- and smooth muscle-derived cells transformed by a temperature-sensitive mutant of SV40 T antigen. J Cell Sci. 1996 Feb; 109 ( Pt 2):397-407. PMID: 8838663

Mii S, Khalil RA, Morgan KG, Ware JA, Kent KC. Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells. Am J Physiol. 1996 Jan; 270(1 Pt 2):H142-50. PMID: 8769745

Walsh MP, Horowitz A, Clément-Chomienne O, Andrea JE, Allen BG, Morgan KG. Protein kinase C mediation of Ca(2+)-independent contractions of vascular smooth muscle. Biochem Cell Biol. 1996; 74(4):485-502. PMID: 8960355

Khalil RA, Morgan KG. Biochemistry of Smooth Muscle Contraction, Bárány M ed. Enzyme translocations during smooth muscle activation. Academic Press. San Diego. 1996; 307-318.

Khalil RA, Menice CB, Wang CL, Morgan KG. Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cells. Circ Res. 1995 Jun; 76(6):1101-8. PMID: 7538916

Yoo J, Ellis R, Morgan KG, Hai CM. Mechanosensitive modulation of myosin phosphorylation and phosphatidylinositol turnover in smooth muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1657-65. PMID: 7810608

Walsh MP, Andrea JE, Allen BG, Clément-Chomienne O, Collins EM, Morgan KG. Smooth muscle protein kinase C. Can J Physiol Pharmacol. 1994 Nov; 72(11):1392-9. PMID: 7767884

Parker CA, Takahashi K, Tao T, Morgan KG. Agonist-induced redistribution of calponin in contractile vascular smooth muscle cells. Am J Physiol. 1994 Nov; 267(5 Pt 1):C1262-70. PMID: 7526695

Doctrow SR, Abelleira SM, Curry LA, Heller-Harrison R, Kozarich JW, Malfroy B, McCarroll LA, Morgan KG, Morrow AR, Musso GF, et al. The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells. J Pharmacol Exp Ther. 1994 Oct; 271(1):229-37.View Related Profiles.

Morgan, Kathleen
Doctrow, Susan

PMID: 7965719

Liou YM, Morgan KG. Redistribution of protein kinase C isoforms in association with vascular hypertrophy of rat aorta. Am J Physiol. 1994 Oct; 267(4 Pt 1):C980-9. PMID: 7943294

Szal SE, Repke JT, Seely EW, Graves SW, Parker CA, Morgan KG. [Ca2+]i signaling in pregnant human myometrium. Am J Physiol. 1994 Jul; 267(1 Pt 1):E77-87. PMID: 8048517

Kiuchi K, Shannon RP, Sato N, Bigaud M, Lajoie C, Morgan KG, Vatner SF. Factors involved in delaying the rise in peripheral resistance in developing heart failure. Am J Physiol. 1994 Jul; 267(1 Pt 2):H211-6. PMID: 7914064

Khalil RA, Lajoie C, Morgan KG. In situ determination of [Ca2+]i threshold for translocation of the alpha-protein kinase C isoform. Am J Physiol. 1994 Jun; 266(6 Pt 1):C1544-51. PMID: 8023886

Kiuchi K, Sato N, Shannon RP, Vatner DE, Morgan K, Vatner SF. Depressed beta-adrenergic receptor- and endothelium-mediated vasodilation in conscious dogs with heart failure. Circ Res. 1993 Dec; 73(6):1013-23. PMID: 7693360

Morgan KG. Ca2+i versus [Ca2+]i. Biophys J. 1993 Aug; 65(2):561-2. PMID: 8218883; PMCID: PMC1225755

Khalil RA, Morgan KG. PKC-mediated redistribution of mitogen-activated protein kinase during smooth muscle cell activation. Am J Physiol. 1993 Aug; 265(2 Pt 1):C406-11. PMID: 8368270

Aburto TK, Lajoie C, Morgan KG. Mechanisms of signal transduction during alpha 2-adrenergic receptor-mediated contraction of vascular smooth muscle. Circ Res. 1993 Apr; 72(4):778-85. PMID: 8095186

Katsuyama H, Morgan KG. Mechanisms of Ca(2+)-independent contraction in single permeabilized ferret aorta cells. Circ Res. 1993 Mar; 72(3):651-7. PMID: 8381724

Perreault CL, Hague NL, Morgan KG, Allen PD, Morgan JP. Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro. Cardiovasc Res. 1993 Feb; 27(2):262-8. PMID: 8472278

Simons M, Morgan KG, Parker C, Collins E, Rosenberg RD. The proto-oncogene c-myb mediates an intracellular calcium rise during the late G1 phase of the cell cycle. J Biol Chem. 1993 Jan 5; 268(1):627-32. PMID: 8416967

Morgan KG. Signal Transduction in Lung Cells, 65th vol. of Lung Biology in Health and Disease, Lenfant C, Brody J, Tkachulk VA, Center DM, eds. Role of calcium in the regulation of smooth muscle tone. Marcel Decker. New York. 1993; 335-349.

Khalil RA, Lajoie C, Resnick MS, Morgan KG. Ca(2+)-independent isoforms of protein kinase C differentially translocate in smooth muscle. Am J Physiol. 1992 Sep; 263(3 Pt 1):C714-9. PMID: 1415520

Khalil RA, Morgan KG. Phenylephrine-induced translocation of protein kinase C and shortening of two types of vascular cells of the ferret. J Physiol. 1992 Sep; 455:585-99. PMID: 1484363; PMCID: PMC1175660

Katsuyama H, Wang CL, Morgan KG. Regulation of vascular smooth muscle tone by caldesmon. J Biol Chem. 1992 Jul 25; 267(21):14555-8. PMID: 1386078

Collins EM, Walsh MP, Morgan KG. Contraction of single vascular smooth muscle cells by phenylephrine at constant [Ca2+]i. Am J Physiol. 1992 Mar; 262(3 Pt 2):H754-62. PMID: 1558185

Pawlowski J, Morgan KG. Mechanisms of intrinsic tone in ferret vascular smooth muscle. J Physiol. 1992 Mar; 448:121-32. PMID: 1593466; PMCID: PMC1176190

Khalil RA, Morgan KG. Protein kinase C—A second E-C coupling pathway in vascular smooth muscle. News in Physiological Sciences. 1992; 7:10-15.

Morgan KG, Khalil RA, Suematsu E, Katsuyama H. Calcium-dependent and calcium-independent pathways of signal transduction in smooth muscle. Jpn J Pharmacol. 1992; 58 Suppl 2:47P-53P. PMID: 1507643

Khalil RA, Morgan KG. Imaging of protein kinase C distribution and translocation in living vascular smooth muscle cells. Circ Res. 1991 Dec; 69(6):1626-31. PMID: 1954682

Suematsu E, Resnick M, Morgan KG. Change of Ca2+ requirement for myosin phosphorylation by prostaglandin F2 alpha. Am J Physiol. 1991 Aug; 261(2 Pt 1):C253-8. PMID: 1872370

Papageorgiou P, Morgan KG. Increased Ca2+ signaling after alpha-adrenoceptor activation in vascular hypertrophy. Circ Res. 1991 Apr; 68(4):1080-4. PMID: 2009608

Egashira K, Morgan KG, Morgan JP. Effects of cocaine on excitation-contraction coupling of aortic smooth muscle from the ferret. J Clin Invest. 1991 Apr; 87(4):1322-8. PMID: 2010545; PMCID: PMC295164; DOI: 10.1172/JCI115135;

Resnick MS, Maitland LA, Morgan KG. Flosequinan, a vasodilator with a novel mechanism of action. Br J Pharmacol. 1991 Apr; 102(4):974-8. PMID: 1855126; PMCID: PMC1917979

Morgan JP, Perreault CL, Morgan KG. The cellular basis of contraction and relaxation in cardiac and vascular smooth muscle. Am Heart J. 1991 Mar; 121(3 Pt 1):961-8. PMID: 1848034

Papageorgiou P, Morgan KG. Intracellular free Ca2+ is elevated in hypertrophic aortic muscle from hypertensive rats. Am J Physiol. 1991 Feb; 260(2 Pt 2):H507-15. PMID: 1996693

Perreault CL, Morgan KG, Morgan JP. Effects of cocaine on intracellular calcium handling in cardiac and vascular smooth muscle. NIDA Res Monogr. 1991; 108:139-53. PMID: 1749409

Morgan KG, Papageorgiou P. [Ca2+]i distribution and signalling in vascular hypertrophy. Adv Exp Med Biol. 1991; 304:303-14. PMID: 1803905

Suematsu E, Resnick M, Morgan KG. Ca(2+)-independent change in phosphorylation of the myosin light chain during relaxation of ferret aorta by vasodilators. J Physiol. 1991; 440:85-93. PMID: 1839559; PMCID: PMC1180141

Morgan KG, Suematsu E. Effects of calcium on vascular smooth muscle tone. Am J Hypertens. 1990 Dec; 3(12 Pt 2):291S-298S. PMID: 2078315

Morgan KG. The role of calcium in the control of vascular tone as assessed by the Ca2+ indicator aequorin. Cardiovasc Drugs Ther. 1990 Oct; 4(5):1355-62. PMID: 2278871

Brozovich FV, Walsh MP, Morgan KG. Regulation of force in skinned, single cells of ferret aortic smooth muscle. Pflugers Arch. 1990 Aug; 416(6):742-9. PMID: 2247345

Papageorgiou P, Morgan KG. The nuclear-cytoplasmic [Ca2+] gradient in single mammalian vascular smooth muscle cells. Proc Soc Exp Biol Med. 1990 Apr; 193(4):331-4. PMID: 2320603

Brozovich FV, Morgan KG. Stimulus-specific changes in mechanical properties of vascular smooth muscle. Am J Physiol. 1989 Nov; 257(5 Pt 2):H1573-80. PMID: 2589511

Morgan KG, Papageorgiou P, Jiang MJ. Pathophysiologic role of calcium in the development of vascular smooth muscle tone. Am J Cardiol. 1989 Sep 19; 64(11):35F-40F. PMID: 2675588

Weinstein JS, Grossman W, Weintraub RM, Thurer RL, Johnson RG, Morgan KG. Differences in alpha-adrenergic responsiveness between human internal mammary arteries and saphenous veins. Circulation. 1989 Jun; 79(6):1264-70. PMID: 2566395

Ruzycky AL, Morgan KG. Involvement of the protein kinase C system in calcium-force relationships in ferret aorta. Br J Pharmacol. 1989 Jun; 97(2):391-400. PMID: 2758222; PMCID: PMC1854504

DeFeo TT, Morgan KG. Calcium-force coupling mechanisms during vasodilator-induced relaxation of ferret aorta. J Physiol. 1989 May; 412:123-33. PMID: 2600829; PMCID: PMC1190567

Jiang MJ, Morgan KG. Agonist-specific myosin phosphorylation and intracellular calcium during isometric contractions of arterial smooth muscle. Pflugers Arch. 1989 Apr; 413(6):637-43. PMID: 2726426

Morgan KG, Brozovich FV. Essential Hypertension and Calcium: Calcium Ions, Calcium Channels, Calcium Agonists and Antagonists. Intracellular calcium levels and arterial smooth muscle function. Academic Press. New York. 1989; 84-111.
Morgan JP, Morgan KG. Intracellular calcium and cardiovascular function in heart failure; effects of pharmacologic agents. Cardiovasc Drugs and Ther. 1989; 3(3):959-970.

Morgan KG, Brozovich FV, Jiang M. Measurements of intracellular calcium concentration in mammalian vascular smooth muscle cells during agonist-induced contractions. Biochem Soc Trans. 1988 Aug; 16(4):493. PMID: 3208976

Morgan KG, Bradley A, DeFeo TT. Calcium transients in smooth muscle. Ann N Y Acad Sci. 1988; 522:328-37. PMID: 3288052

DeFeo TT, Briggs GM, Morgan KG. Ca2+ signals obtained with multiple indicators in mammalian vascular muscle cells. Am J Physiol. 1987 Dec; 253(6 Pt 2):H1456-61. PMID: 3425745

Jiang MJ, Morgan KG. Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle. Am J Physiol. 1987 Dec; 253(6 Pt 2):H1365-71. PMID: 3425738

Bradley AB, Morgan KG. Alterations in cytoplasmic calcium sensitivity during porcine coronary artery contractions as detected by aequorin. J Physiol. 1987 Apr; 385:437-48. PMID: 3477639; PMCID: PMC1192353

Morgan KG. Calcium and vascular smooth muscle tone. Am J Med. 1987 Mar 30; 82(3B):9-15. PMID: 3551603

Morgan KG. Role of calcium ion in maintenance of vascular smooth muscle tone. Am J Cardiol. 1987 Jan 23; 59(2):24A-28A. PMID: 3812260

Morgan KG, Jiang MJ. Measurement of cytoplasmic Ca2+ during tonic and phasic contractions of mammalian smooth muscle. Excerpta Medica Elsevier Science Publishers; International Congress Series. 1987; 725:109-123.

DeFeo TT, Morgan KG. A comparison of two different indicators: quin 2 and aequorin in isolated single cells and intact strips of ferret portal vein. Pflugers Arch. 1986 Apr; 406(4):427-9. PMID: 3714445

Morgan JP, Gwathmey JK, DeFeo TT, Morgan KG. The effects of amrinone and related drugs on intracellular calcium in isolated mammalian cardiac and vascular smooth muscle. Circulation. 1986 Mar; 73(3 Pt 2):III65-77. PMID: 3943182

DeFeo TT, Morgan KG. Calcium-force relationships as detected with aequorin in two different vascular smooth muscles of the ferret. J Physiol. 1985 Dec; 369:269-82. PMID: 4093883; PMCID: PMC1192648

Morgan KG, DeFeo TT, Wenc K, Weinstein R. Alterations of excitation-contraction coupling by platelet-derived growth factor in enzymatically isolated and cultured vascular smooth muscle cells. Pflugers Arch. 1985 Sep; 405(1):77-9. PMID: 3903652

Morgan KG, Angel F, Schmalz PF, Szurszewski JH. Intracellular electrical activity of muscularis mucosae of the dog stomach. Am J Physiol. 1985 Aug; 249(2 Pt 1):G256-63. PMID: 2411148

DeFeo TT, Morgan KG. Responses of enzymatically isolated mammalian vascular smooth muscle cells to pharmacological and electrical stimuli. Pflugers Arch. 1985 May; 404(1):100-2. PMID: 3892474

Bradley AB, Morgan KG. Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. Am J Physiol. 1985 Jan; 248(1 Pt 2):H109-17. PMID: 3970168

Morgan JP, Morgan KG. Alteration of cytoplasmic ionized calcium levels in smooth muscle by vasodilators in the ferret. J Physiol. 1984 Dec; 357:539-51. PMID: 6096534; PMCID: PMC1193274

Morgan JP, Morgan KG. Calcium and cardiovascular function. Intracellular calcium levels during contraction and relaxation of mammalian cardiac and vascular smooth muscle as detected with aequorin. Am J Med. 1984 Nov 5; 77(5A):33-46. PMID: 6496558

Morgan JP, Morgan KG. Stimulus-specific patterns of intracellular calcium levels in smooth muscle of ferret portal vein. J Physiol. 1984 Jun; 351:155-67. PMID: 6747864; PMCID: PMC1193111

Morgan JP, DeFeo TT, Morgan KG. A chemical procedure for loading the calcium indicator acquorin into mammalian working myocardium. Pflugers Arch. 1984 Mar; 400(3):338-40. PMID: 6728654

Morgan KG. Comparison of membrane electrical activity of cat gastric submucosal arterioles and venules. J Physiol. 1983 Dec; 345:135-47. PMID: 6663496; PMCID: PMC1193789

Schmalz PF, Morgan KG, Szurszewski JH. Pentagastrin potentiates nonadrenergic inhibitory neuromuscular transmission in orad stomach of the dog. Am J Physiol. 1983 Oct; 245(4):G597-600. PMID: 6312813

Morgan KG. Electrophysiological differentiation of alpha-receptors on arteriolar smooth muscle. Am J Physiol. 1983 Apr; 244(4):H540-5. PMID: 6301291

Morgan JP, Morgan KG. Vascular smooth muscle: the first recorded Ca2+ transients. Pflugers Arch. 1982 Oct; 395(1):75-7. PMID: 7177776

Angel F, Schmalz PF, Morgan KG, Go VL, Szurszewski JH. Innervation of the muscularis mucosa in the canine stomach and colon. Scand J Gastroenterol Suppl. 1982; 71:71-5. PMID: 6176013

Morgan KG, Muir TC, Szurszewski JH. The electrical basis for contraction and relaxation in canine fundal smooth muscle. J Physiol. 1981 Feb; 311:475-88. PMID: 7264980; PMCID: PMC1275424

Neering IR, Morgan KG. Use of aequorin to study excitation--contraction coupling in mammalian smooth muscle. Nature. 1980 Dec 11; 288(5791):585-7. PMID: 7192366

Morgan KG, Szurszewski JH. Mechanisms of phasic and tonic actions of pentagastrin on canine gastric smooth muscle. J Physiol. 1980 Apr; 301:229-42. PMID: 7411429; PMCID: PMC1279394

Morgan KG, Schmalz PF, Go VL, Szurszewski JH. Effects of pentagastrin, G17, and G34 on the electrical and mechanical activities of canine antral smooth muscle. Gastroenterology. 1978 Sep; 75(3):405-12. PMID: 680495

Telander RL, Morgan KG, Kreulen DL, Schmalz PF, Kelly KA, Szurszewski JH. Human gastric atony with tachygastria and gastric retention. Gastroenterology. 1978 Sep; 75(3):497-501. PMID: 680507

Morgan KG, Schmalz PF, Go VL, Szurszewski JH. Electrical and mechanical effects of molecular variants of CCK on antral smooth muscle. Am J Physiol. 1978 Sep; 235(3):E324-9. PMID: 696826

Morgan KG, Schmalz PF, Szurszewski JH. The inhibitory effects of vasoactive intestinal polypeptide on the mechanical and electrical activity of canine antral smooth muscle. J Physiol. 1978 Sep; 282:437-50. PMID: 722548; PMCID: PMC1282750

el-Sharkawy TY, Morgan KG, Szurszewski JH. Intracellular electrical activity of canine and human gastric smooth muscle. J Physiol. 1978 Jun; 279:291-307. PMID: 671352; PMCID: PMC1282616

Morgan KG, Bryant SH. Pentobarbital: presynaptic effect in the squid giant synapse. Experientia. 1977 Apr 15; 33(4):487-8. PMID: 862741

Morgan KG, Bryant SH. The mechanism of action of dantrolene sodium. J Pharmacol Exp Ther. 1977 Apr; 201(1):138-47. PMID: 321754

Morgan KG, Entrikin RK, Bryant SH. Myotonia and block of chloride conductance by iodide in avian muscle. Am J Physiol. 1975 Nov; 229(5):1155-8. PMID: 1200133

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 177 publications over 43 distinct years, with a maximum of 10 publications in 1991 and 1996

Bar chart showing 177 publications over 43 distinct years, with a maximum of 10 publications in 1991 and 1996

Year	Publications
1980	2
1981	1
1982	2
1983	3
1984	4
1985	5
1986	2
1987	6
1988	2
1989	8
1990	4
1991	10
1992	7
1993	8
1994	8
1995	1
1996	10
1997	5
1998	3
1999	8
2000	7
2001	5
2002	3
2003	4
2004	3
2005	3
2006	2
2007	4
2008	6
2009	3
2010	4
2011	3
2012	7
2013	6
2014	3
2015	2
2016	2
2017	1
2018	1
2020	2
2021	3
2022	3
2023	1