Deciphering the Principles of Membrane-Associated Glycan Assembly for Glycoconjugate Biosynthesis04/01/2022 - 02/28/2026 (Multi-PI)
PI:
Karen N. Allen, PhDMassachusetts Institute of Technology NIH NIGMS5R01GM039334-35
Structural and functional characterization of glycosyltransferases in the
Campylobacter concisus N-linked glycoconjugate biosynthetic pathway02/01/2023 - 01/31/2025 (Key Person / Mentor)
PI:
Nemanja VuksanovicNIH/National Institute of General Medical Sciences5F32GM146421-02
Structure and function of the monotopic phosphoglycosyl transferase superfamily: Initiators of biosynthesis of complex bacterial glycoconjugates08/01/2021 - 07/31/2024 (Multi-PI)
PI:
Karen N. Allen, PhDMassachusetts Institute of Technology NIH NIGMS2R01GM131627-03A1
Covalent Inhibition as a Method to Counteract Botulinum Intoxication06/02/2020 - 05/31/2024 (Subcontract PI)
The Scripps Research Institute NIH NIAID5R01AI153298-03
Acquisition of a Single Crystal X-ray Diffraction System for Macromolecular and Small Molecule Crystallography06/01/2021 - 05/31/2022 (PI)
NIH/Office of the Director1S10OD028585-01A1
Structure and function of the monotopic phosphoglycosyl transferase superfamily: Initiators of biosynthesis of complex bacterial glycoconjugates02/01/2019 - 07/31/2021 (Multi-PI)
PI:
Karen N. Allen, PhDMassachusetts Institute of Technology NIH NIGMS5R01GM131627-02
Molecular Mechanism of the NFkappaB Essential Modulator (NEMO) Scaffold
Protein Mutated in Human Immunodeficiencies08/15/2016 - 06/30/2021 (Co-Investigator)
PI:
Adrian Whitty, PhDNIH/National Institute of General Medical Sciences5R01GM117350-04
A Multidisciplinary Approach for the Treatment of Botulinum Intoxication08/26/2016 - 06/30/2020 (Subcontract PI)
The Scripps Research Institute NIH NIAID5R01AI19564-04
Trehalose-6-phosphate phosphatase inhibitors as anti-helminthics09/12/2016 - 11/30/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases5R21AI127623-02
Collaborative research: Development of a platform enabling analysis of membrane protein interactions08/01/2016 - 07/31/2018 (PI)
National Science FoundationMCB-1614608
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Structure and Function of HAD Phosphatase Partners Dullard and Lipin09/01/2012 - 05/31/2017 (PI)
NIH/National Institute of General Medical Sciences5R01GM098760-04
COLLABORATIVE CENTER FOR AN ENZYME FUNCTION INITIATIVE05/01/2010 - 04/30/2016 (Subcontract PI)
University of Illinois NIH NIGMS5U54GM093342-05
Trehalose-6-Phosphate Phosphatase: A Target for Anti-Onchocerciasis Therapeutics01/18/2013 - 12/31/2015 (PI)
NIH/National Institute of Allergy & Infectious Diseases5R21AI103484-02
PGT Inhibitors Mapped From A Tunicamycin Blueprint02/01/2013 - 01/31/2015 (Subcontract PI)
Massachusetts Institute of Technology NIH1R21AI101807-01A1
MRI: Acquisition of Circular Dichroism (CD) Spectrometer09/15/2011 - 08/31/2014 (PI)
National Science FoundationCHE-1126545
BIOCHEMICAL STUDIES OF OXALATE DECARBOXYLASE07/01/2012 - 06/30/2014 (Subcontract PI)
Trustees of Indiana University NIH7R01DK061666-08
BIOCHEMICAL STUDIES OF OXALATE DECARBOXYLASE04/15/2010 - 06/30/2014 (Subcontract PI)
University of Florida NIH NIDDK5R01DK061666-09
ENZYMES: STRUCTURE, MECHANISM, FUNCTION AND INHIBITION09/01/2008 - 06/30/2013 (Subcontract PI)
University of New Mexico NIH NIGMS5R01GM028688-29
Small Molecular Inhibitors of Shiga Toxin and Ricin01/01/2008 - 06/30/2010 (PI)
Tufts University NIH NIAID
Discovery of Inhibitors of Botulinum Serotype A, B and E Proteases10/26/2007 - 06/30/2010 (PI)
Tufts University NIH NIAID
MECHANISMS AND FUNCTION IN HAD PHOSPHOTRANSFERASES - BUMC STUDENT SOURCE03/01/2009 - 02/28/2010 (PI)
NIH/National Institute of General Medical Sciences7R01GM061099-09
Mechanism and Function in HAD Phosphotransferases04/01/2000 - 02/28/2010 (PI)
NIH/National Institute of General Medical Sciences5 R01 GM61099 08
Collaborative Research Agreement with Genzyme06/01/2007 - 05/31/2009 (PI)
Genzyme Corporation
Discovery of Inhibitors of Botulinum Proteases07/07/2005 - 07/06/2007 (PI)
Tufts University NIH NIAID
Discovery of Inhibitors of Botulinum Proteases07/07/2004 - 07/06/2005 (PI)
Brigham & Women's Hospital NIH NIAID
Lanthanide Binding Tags: New Chemical Tools for Proteomics08/15/2003 - 07/31/2004 (PI)
Massachusetts Institute of Technology National Science Fdn
Deciphering the Cellular Function of Aldolase06/01/2000 - 05/31/2004 (PI)
NIH/National Institute of General Medical Sciences5 R01 GM1616 04
Enzymes of the Meta-Fission Pathway12/01/1999 - 05/31/2004 (PI)
University of Texas NIH NIGMS
Crystallography on Soluble Receptor Kinases04/15/1997 - 04/30/2000 (PI)
BASF Bioresearch Corporation