Juan Mella, MD
Lahey Hospital & Medical Center
Dept of Plastic Surgery

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My work examines how neurotransmitters, specifically substance P, modulates the septic inflammatory response.

Postdoctoral Fellow (previously held)
Boston University School of Medicine
General Surgery

2013 99th Annual American College of Surgeons Clinical Congress: Excellence in Research Award
2013 36th Annual Conference on Shock : Young Investigator’s Travel Award
2011 Boston University Medical Center : Excellence in Surgical Critical Care Award
2010-2011 Boston University Medical Center : Top ABSITE (American Board of Surgery In-training Examination) Score Award
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Mella JR, Stucchi AF, Duffy ER, Remick DG. Neurokinin-1 Receptor Deficiency Improves Survival in Murine Polymicrobial Sepsis Through Multiple Mechanisms in Aged Mice. Shock. 2019 Jul; 52(1):61-66.View Related Profiles. PMID: 30095600.
  2. Mella JR, Guo L, Hung V. Dupuytren's Contracture: An Evidence Based Review. Ann Plast Surg. 2018 Dec; 81(6S Suppl 1):S97-S101. PMID: 30161050.
  3. Mella JR, Ross KM, Li GZ, Pomahac B, Raut CP, Orgill DP. Cutaneous Breast Radiation-associated Angiosarcoma: Anterior Chest Wall Reconstruction Options Following Extra-radical Resection. Plast Reconstr Surg Glob Open. 2018 Sep; 6(9):e1938. PMID: 30349797.
  4. Mella JR, Chiswick E, Stepien D, Moitra R, Duffy ER, Stucchi A, Remick D. Antagonism of the Neurokinin-1 Receptor Improves Survival in a Mouse Model of Sepsis by Decreasing Inflammation and Increasing Early Cardiovascular Function. Crit Care Med. 2017 Feb; 45(2):e213-e221.View Related Profiles. PMID: 27632670; DOI: 10.1097/CCM.0000000000002075;.
  5. Chiswick EL, Mella JR, Bernardo J, Remick DG. Acute-Phase Deaths from Murine Polymicrobial Sepsis Are Characterized by Innate Immune Suppression Rather Than Exhaustion. J Immunol. 2015 Oct 15; 195(8):3793-802.View Related Profiles. PMID: 26371253; PMCID: PMC4592823; DOI: 10.4049/jimmunol.1500874;.
  6. Kim K, Mella JR, Ibrahim AM, Koolen PG, Lin SJ. Is There an Association between Component Separation and Venous Thromboembolism? Analysis of the NSQIP. Plast Reconstr Surg Glob Open. 2015 Jun; 3(6):e429. PMID: 26180730; DOI: 10.1097/GOX.0000000000000167;.
  7. Gates JD, Arabian S, Biddinger P, Blansfield J, Burke P, Chung S, Fischer J, Friedman F, Gervasini A, Goralnick E, Gupta A, Larentzakis A, McMahon M, Mella J, Michaud Y, Mooney D, Rabinovici R, Sweet D, Ulrich A, Velmahos G, Weber C, Yaffe MB. The initial response to the Boston marathon bombing: lessons learned to prepare for the next disaster. Ann Surg. 2014 Dec; 260(6):960-6.View Related Profiles. PMID: 25386862; DOI: 10.1097/SLA.0000000000000914;.
  8. Mella JR, Chiswick EL, King E, Remick DG. Location, location, location: cytokine concentrations are dependent on blood sampling site. Shock. 2014 Oct; 42(4):337-42.View Related Profiles. PMID: 25004061; PMCID: PMC4167217; DOI: 10.1097/SHK.0000000000000222;.
  9. King EG, Bauzá GJ, Mella JR, Remick DG. Pathophysiologic mechanisms in septic shock. Lab Invest. 2014 Jan; 94(1):4-12.View Related Profiles. PMID: 24061288; DOI: 10.1038/labinvest.2013.110;.
  10. Ahyi AN, Quinton LJ, Jones MR, Ferrari JD, Pepper-Cunningham ZA, Mella JR, Remick DG, Mizgerd JP. Roles of STAT3 in protein secretion pathways during the acute-phase response. Infect Immun. 2013 May; 81(5):1644-53.View Related Profiles. PMID: 23460517; PMCID: PMC3647986; DOI: 10.1128/IAI.01332-12;.
Showing 10 of 11 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 11 publications over 7 distinct years, with a maximum of 2 publications in 2013 and 2014 and 2015 and 2018

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Inflammation Substance P Sepsis
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88 East Newton St., C515
Boston MA 02118
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