Jose Rafael Romero, MD
Associate Professor
Boston University School of Medicine
Dept of Neurology

MD, Escuela Colombiana de Medicina




Dr. Romero completed residency training in neurology at Boston University Medical Campus and fellowship training in vascular neurology at Boston University Medical Campus. He received his medical degree from the Escuela Cololmbiana de Medicina in Colombia. He also completed studies for a Master in Epidemiology at Boston University School of Public Health.
Dr. Romero is an active investigator in the Framingham Heart Study since 2006.

Research Interests
Dr. Romero’s research interests center on the study of cerebrovascular disease in subclinical stages, prevention of stroke, cognitive impairment and dementia and use of neuroimaging in the epidemiological study of cerebrovascular disease. His focus is in the interplay of cerebrovascular disease with the neurodegenerative process, and contributions to clinical stroke and dementia. Much of his current work centers on the epidemiological study of brain MRI markers of cerebral small vessel disease, their determinants and clinical consequences. As a board-certified neurologist and vascular neurologist, his clinical interests are in the prevention, diagnosis, treatment and rehabilitation of patients with stroke, with particular emphasis in racial minority populations. He runs a stroke prevention clinic and is an active member in the Stroke Unit at Boston Medical Center. He is the site PI of several clinical trials for acute stroke treatment and secondary prevention. He has written widely on stroke, cerebrovascular disease in subclinical stages, and epidemiology of stroke and dementia. He has participated as study section reviewer in the NIH- and has obtained grant funding from NIH-NIA for his research support. Dr. Romero has presented the results of his research widely at national and international level and has been invited to participate in several international consortia of experts in cerebrovascular disease. Dr. Romero has contributed significantly to our understanding of cerebral microbleeds in the general population and is now leading the study of enlarged perivascular spaces in the Framingham Heart Study cohorts.

Investigator
Framingham Heart Study



2010-2010 Department of Neurology: resident teaching


Enlarged Perivascular Spaces as Markers of Vascular and Alzheimer pathology: predictors, pathophysiology and clinical consequences
08/01/2019 - 04/30/2024 (PI)
NIH/National Institute on Aging
1R01AG059725-01A1

Genetic Contribution to Brain Arterial Dilatation and its Role in Cognition and Dementia
08/15/2018 - 04/30/2023 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NIA
5R01AG057709-02

Precursors of Stroke Incidence and Prognosis
12/01/2017 - 02/29/2020 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NINDS
5R01NS017950-36

Preclinical AD: Correlates of Amyloid, Tau PET and fcMRI in Framingham Gen 3 Young Adults
12/01/2017 - 01/31/2020 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7R01AG049607-05

Cerebral Microbleeds in Young Adults: Risk Factors, Biomarkers and Genetic Determinants
06/01/2015 - 05/31/2018 (PI)
NIH/National Institute on Aging
5R03AG048180-02

Risk Factors, Genetics and Cognition in Cerebral Microbleeds: Framingham Study
08/15/2011 - 05/31/2017 (PI)
NIH/National Institute on Aging
5K23AG038444-05

Investigation of lipoprotein phospholipase A2 (Lp-PLA2) and cerebral microbleeds (CMBs) in the Framingham Heart Study
11/01/2009 - 06/30/2011 (PI)
GlaxoSmithKline, Inc.



Sleep for Stroke Management and Recovery Trial (Sleep SMART)
08/15/2018 - 07/31/2024 (PI)
Univ of Cincinnati NIH-NINDS

Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial-NCC Admin
06/01/2018 - 04/30/2024 (PI)
Univ of Cincinnati NIH-NINDS
1U01NS100699-01A1

New England Regional Coordinating Center for the NINDS Stroke Trials Network
08/01/2018 - 07/31/2023 (PI)
Mass General Hosp NIH-NINDS
5U24NS107243-02

NIH StrokeNet Clinical Coordinating Center Master Trial Agreement (MTA) - Satellites
09/30/2013 - 05/31/2020 (PI)
Univ of Cincinnati NIH-NINDS

CV006004
08/24/2016 - 07/01/2019 (PI)
Bristol-Myers

POINT Study: Platelet-Oriented Inhibition in New TIA
02/01/2010 - 04/30/2019 (PI)
EMMES Corporation NIH-NINDS
2U01NS062835-06

Mild and Rapidly Improving Stroke Symptoms 'MaRISS' Research Study No. NEA-31
04/01/2015 - 04/01/2019 (PI)
American Heart Assoc

New England Regional Coordinating Center for the NINDS Stroke Trials Network
09/30/2013 - 07/31/2018 (PI)
Mass General Hosp NIH-NINDS


Title

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Penton AA, Lau H, Babikian VL, Shulman J, Cervantes-Arslanian A, Gangadhara S, Greer D, Aparicio HJ, Romero JR. Chronic Kidney Disease as Risk Factor for Enlarged Perivascular Spaces in Patients With Stroke and Relation to Racial Group. Stroke. 2020 Oct 06; STROKEAHA119028688.View Related Profiles. PMID: 33019895
     
  2. Petrea RE, O'Donnell A, Beiser AS, Habes M, Aparicio H, DeCarli C, Seshadri S, Romero JR. Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study. Hypertension. 2020 Sep; 76(3):707-714.View Related Profiles. PMID: 32755403
     
  3. Lioutas VA, Beiser AS, Aparicio HJ, Himali JJ, Selim MH, Romero JR, Seshadri S. Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016. JAMA Neurol. 2020 Jun 08.View Related Profiles. PMID: 32511690
     
  4. Ford T, Curiale G, Nguyen TN, Aparicio H, Hamlyn EK, Gangadhara S, Cervantes-Arslanian AM, Greer D, Romero JR, Shulman JG. Optimization of resources and modifications in acute ischemic stroke care in response to the global COVID-19 pandemic. J Stroke Cerebrovasc Dis. 2020 Aug; 29(8):104980.View Related Profiles. PMID: 32689645
     
  5. Baradaran H, Demissie S, Himali JJ, Beiser A, Gupta A, Polak JF, DeCarli C, Seshadri S, Romero JR. The progression of carotid atherosclerosis and imaging markers of dementia. Alzheimers Dement (N Y). 2020; 6(1):e12015.View Related Profiles. PMID: 32296732
     
  6. Charidimou A, Frosch MP, Al-Shahi Salman R, Baron JC, Cordonnier C, Hernandez-Guillamon M, Linn J, Raposo N, Rodrigues M, Romero JR, Schneider JA, Schreiber S, Smith EE, van Buchem MA, Viswanathan A, Wollenweber FA, Werring DJ, Greenberg SM. Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. Int J Stroke. 2019 12; 14(9):956-971. PMID: 31514686
     
  7. Pase MP, Himali JJ, Aparicio HJ, Romero JR, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S. Plasma total-tau as a biomarker of stroke risk in the community. Ann Neurol. 2019 09; 86(3):463-467.View Related Profiles. PMID: 31271449
     
  8. Aparicio HJ, Himali JJ, Satizabal CL, Pase MP, Romero JR, Kase CS, Beiser AS, Seshadri S. Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study. Stroke. 2019 06; 50(6):1558-1560.View Related Profiles. PMID: 31084341
     
  9. Romero JR. May 2019 Highlights. Stroke. 2019 May; 50(5):1045. PMID: 31371838
     
  10. Smith EE, Biessels GJ, De Guio F, de Leeuw FE, Duchesne S, Düring M, Frayne R, Ikram MA, Jouvent E, MacIntosh BJ, Thrippleton MJ, Vernooij MW, Adams H, Backes WH, Ballerini L, Black SE, Chen C, Corriveau R, DeCarli C, Greenberg SM, Gurol ME, Ingrisch M, Job D, Lam BYK, Launer LJ, Linn J, McCreary CR, Mok VCT, Pantoni L, Pike GB, Ramirez J, Reijmer YD, Romero JR, Ropele S, Rost NS, Sachdev PS, Scott CJM, Seshadri S, Sharma M, Sourbron S, Steketee RME, Swartz RH, van Oostenbrugge R, van Osch M, van Rooden S, Viswanathan A, Werring D, Dichgans M, Wardlaw JM. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimers Dement (Amst). 2019 Dec; 11:191-204.View Related Profiles. PMID: 30859119
     
Showing 10 of 61 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 61 publications over 18 distinct years, with a maximum of 7 publications in 2019

YearPublications
20024
20041
20051
20061
20072
20082
20095
20102
20115
20122
20133
20143
20154
20164
20176
20184
20197
20205


Recent (within 3 months)

Sustained high blood pressure may damage brain vessels

Health Day 7/31/2020
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