John Stone | Profiles RNS

John Stone, MD

Instructor

Boston University Chobanian & Avedisian School of Medicine

Medicine

General Internal Medicine

I grew up in Syracuse, NY, and spent my early adulthood in Albany, NY while studying at Siena College and subsequently Albany Medical College. During my time in undergrad as well as medical school, I was fortunate to work directly with underserved communities both locally and abroad, and naturally was drawn to the mission of Boston Medical Center to pursue my Internal Medicine training. After three incredible years of residency at BMC, I am thrilled to start my new role as the VA Boston Clinical Chief at West Roxbury and serve our nation’s veterans. After chief year, I plan on pursuing a career in academic cardiology and medical education.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Stone JH. IgG4-related disease: lessons from the first 20 years. Rheumatology (Oxford). 2025 Mar 01; 64(Supplement_1):i24-i27. PMID: 40071397

Kothari OA, Stone J, Manivannan A, Segarra-Concepcion A, Ferri GM, Ganti R, Gurnani SD, Gurijala N, Toro C, Bosch NA, Claudel SE. Statin Use and Cardiovascular Risk in Young Adults in the United States. Am J Prev Med. 2025 May; 68(5):1028-1031.View Related Profiles.

Manivannan, Alan
Toro, Camilo
Ferri, Grace
Stone, John
Bosch, Nicholas
Claudel, Sophie

PMID: 39922395; PMCID: PMC12033075; DOI: 10.1016/j.amepre.2025.02.001;

Stone JH, Khosroshahi A, Zhang W, Della Torre E, Okazaki K, Tanaka Y, Löhr JM, Schleinitz N, Dong L, Umehara H, Lanzillotta M, Wallace ZS, Ebbo M, Webster GJ, Martinez Valle F, Nayar MK, Perugino CA, Rebours V, Dong X, Wu Y, Li Q, Rampal N, Cimbora D, Culver EL. Inebilizumab for Treatment of IgG4-Related Disease. N Engl J Med. 2025 Mar 27; 392(12):1168-1177. PMID: 39541094

Katz G, Perugino C, Wallace ZS, Jiang B, Guy T, McMahon GA, Jha I, Zhang Y, Liu H, Fernandes AD, Pillai SS, Atkinson JP, Kim AH, Stone JH. Multiorgan involvement and circulating IgG1 predict hypocomplementaemia in IgG4-related disease. Ann Rheum Dis. 2024 Nov 14; 83(12):1773-1780. PMID: 39079893; PMCID: PMC11563845; DOI: 10.1136/ard-2024-225846;

McDowell PJ, Busby J, Stone JH, Butler CA, Heaney LG. Longitudinal Assessment of Glucocorticoid Toxicity Reduction in Patients With Severe Asthma Treated With Biologic Therapies. J Allergy Clin Immunol Pract. 2025 Feb; 13(2):298-307.e10. PMID: 39477016

Cai S, Chen Y, Hu Z, Lin S, Gao R, Ming B, Zhong J, Sun W, Chen Q, Stone JH, Dong L. Omics in IgG4-related disease. Chin Med J (Engl). 2025 Jul 20; 138(14):1665-1675. PMID: 39450944; PMCID: PMC12273674; DOI: 10.1097/CM9.0000000000003320;

O'Driscoll J, Burton A, Maskarinec G, Perez-Gomez B, Vachon C, Miao H, Lajous M, López-Ridaura R, Eliassen AH, Pereira A, Garmendia ML, Tamimi RM, Bertrand K, Kwong A, Ursin G, Lee E, Qureshi SA, Ma H, Vinnicombe S, Moss S, Allen S, Ndumia R, Vinayak S, Teo SH, Mariapun S, Fadzli F, Peplonska B, Nagata C, Stone J, Hopper JL, Giles G, Ozmen V, Aribal ME, Schüz J, Van Gils CH, Wanders JOP, Sirous R, Sirous M, Hipwell J, Kim J, Lee JW, Hartman M, Li J, Scott C, Chiarelli AM, Linton L, Pollan M, Flugelman AA, Salem D, Kamal R, Boyd N, Dos-Santos-Silva I, McCormack V, Mullooly M. Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study. Breast Cancer Res. 2024 Sep 30; 26(1):139.View Related Profiles.

Stone, John
Bertrand, Kimberly

PMID: 39350230; PMCID: PMC11443712; DOI: 10.1186/s13058-024-01890-x;

Chen LYC, Huang AJ, Stone JH, Ferry JA. Case 30-2024: A 45-Year-Old Woman with Kidney Lesions and Lytic Bone Disease. N Engl J Med. 2024 Sep 26; 391(12):1140-1151. PMID: 39321367

Wallace ZS, Miles G, Smolkina E, Petruski-Ivleva N, Madziva D, Guzzo K, Cook C, Fu X, Zhang Y, Stone JH, Choi HK. The clinical outcomes and healthcare resource utilization in IgG4-related disease: a claims-based analysis of commercially insured adults in the United States. Rheumatology (Oxford). 2024 Sep 01; 63(9):2457-2466. PMID: 38637947; PMCID: PMC11371374; DOI: 10.1093/rheumatology/keae230;

Zhang E, Capponi S, Scobell R, Alonzi G, Hlobik M, Daga A, Meidan E, Wobma H, Kim L, Henderson LA, Case S, Nigrovic PA, Stone JH, Costenbader KH, Son MBF, Chang JC. Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Semin Arthritis Rheum. 2024 Oct; 68:152516. PMID: 39059156; PMCID: PMC11381140; DOI: 10.1016/j.semarthrit.2024.152516;

Showing 10 of 181 results. Show More

Stone JH, McDowell PJ, Jayne DRW, Merkel PA, Robson J, Patel NJ, Zhang Y, Yue H, Bekker P, Heaney LG. Corrigendum to "The Glucocorticoid Toxicity Index: Measuring Change in Glucocorticoid Toxicity Over Time" [Seminars in Arthritis and Rheumatism 55 (2022):152010]. Semin Arthritis Rheum. 2024 Oct; 68:152496. PMID: 38954998

Stone J, Kumar M, Orkaby AR. The role of statin therapy in older adults: best practices and unmet challenges. Expert Rev Cardiovasc Ther. 2024 Jul; 22(7):301-311.View Related Profiles.

Orkaby, Ariela
Stone, John

PMID: 38940676; PMCID: PMC11331431; DOI: 10.1080/14779072.2024.2371968;

Jha I, McMahon GA, Perugino CA, Katz G, Wallace ZS, Fernandes A, Jiang B, Zhang Y, McMahon AE, Guy TV, Liu H, Hernandez-Barco YG, Pillai S, Stone JH. Sex as a predictor of clinical phenotype and determinant of immune response in IgG4-related disease: a retrospective study of patients fulfilling the American College of Rheumatology-European League Against Rheumatism classification criteria. Lancet Rheumatol. 2024 Jul; 6(7):e460-e468. PMID: 38824935; PMCID: PMC11214762; DOI: 10.1016/S2665-9913(24)00089-4;

Lanzillotta M, Culver E, Sharma A, Zen Y, Zhang W, Stone JH, Della-Torre E. Fibrotic phenotype of IgG4-related disease. Lancet Rheumatol. 2024 Jul; 6(7):e469-e480. PMID: 38574746

O'Shea A, Crotty RK, Randhawa MK, Oliveira G, Perugino CA, Stone JH, Harisinghani MG, Wallace ZS, Hedgire SS. Multimodality Imaging Features of Immunoglobulin G4-related Vessel Involvement. Radiol Cardiothorac Imaging. 2024 Apr; 6(2):e230105. PMID: 38483247; PMCID: PMC11056752; DOI: 10.1148/ryct.230105;

Kronbichler A, Bajema IM, Bruchfeld A, Mastroianni Kirsztajn G, Stone JH. Diagnosis and management of ANCA-associated vasculitis. Lancet. 2024 Feb 17; 403(10427):683-698. PMID: 38368016

Howell TA, Matza LS, Stone JH, Gelinas D, Stone MN, Rao VTS, Phillips GA. Qualitative interviews to support development of a patient-reported companion measure to the Glucocorticoid Toxicity Index. J Neurol Sci. 2024 Mar 15; 458:122907. PMID: 38309251

Koga R, Maehara T, Aoyagi R, Munemura R, Murakami Y, Doi A, Kono M, Yamamoto H, Niiro H, Kiyoshima T, Tanabe M, Nakano T, Matsukuma Y, Kawano M, Stone JH, Pillai S, Nakamura S, Kawano S. Granzyme K- and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease. J Allergy Clin Immunol. 2024 Apr; 153(4):1095-1112. PMID: 38092138

Schmidt WA, Dasgupta B, Sloane J, Giannelou A, Xu Y, Unizony SH, Mackie SL, Gonzalez-Gay MA, Spiera R, Warrington KJ, Villiger PM, Nivens MC, Akinlade B, Lin Y, Buttgereit F, Stone JH. A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of sarilumab in patients with giant cell arteritis. Arthritis Res Ther. 2023 Oct 16; 25(1):199. PMID: 37840134; PMCID: PMC10577982; DOI: 10.1186/s13075-023-03177-6;

Perugino C, Culver EL, Khosroshahi A, Zhang W, Della-Torre E, Okazaki K, Tanaka Y, Löhr M, Schleinitz N, Falloon J, She D, Cimbora D, Stone JH. Efficacy and Safety of Inebilizumab in IgG4-Related Disease: Protocol for a Randomized Controlled Trial. Rheumatol Ther. 2023 Dec; 10(6):1795-1808. PMID: 37792260; PMCID: PMC10654302; DOI: 10.1007/s40744-023-00593-7;

Wallace ZS, McMahon GA, Hang B, Fu X, Harkness T, Donelan K, Fernandes A, Cook C, Katz G, Perugino C, Stone JH. Assessment of patient-reported symptoms and distress in IgG4-related disease (IgG4-RD): Development, clinical validation, and content validation of the IgG4-RD Symptom Severity Index. Semin Arthritis Rheum. 2023 Dec; 63:152253. PMID: 37619485; PMCID: PMC11004491; DOI: 10.1016/j.semarthrit.2023.152253;

Perugino CA, Wallace ZS, Zack DJ, Quinn SM, Poma A, Fernandes AD, Foster P, DeMattos S, Burington B, Liu H, Allard-Chamard H, Smith N, Kai X, Xing K, Pillai S, Stone JH. Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial. Lancet Rheumatol. 2023 Aug; 5(8):e442-e450. PMID: 38251576

Wallace ZS, Fu X, Cook C, Ahola C, Williams Z, Doliner B, Hanberg JS, Stone JH, Zhang Y, Choi HK. Comparative Effectiveness of Rituximab- Versus Cyclophosphamide-Based Remission Induction Strategies in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis for the Risk of Kidney Failure and Mortality. Arthritis Rheumatol. 2023 Sep; 75(9):1599-1607. PMID: 37011036; PMCID: PMC10523845; DOI: 10.1002/art.42515;

Gill T, Putman M, Sattui SE, Hamdulay S, Conway R, Liew DFL, Sharma A, Stone JH, Mackie SL, Mehta P. Should race be considered in diagnosing giant cell arteritis? - Authors' reply. Lancet Rheumatol. 2023 Jul; 5(7):e372-e373. PMID: 38251547

Patel NJ, Jayne DRW, Merkel PA, Bekker P, Zhang Y, McDowell PJ, Johal J, Heaney LG, Murrell D, Stone MN, Yue H, Stone JH. The Glucocorticoid Toxicity Index-Metabolic Domains, an abridged version of the Glucocorticoid Toxicity Index: post-hoc analysis of data from the ADVOCATE trial. Lancet Rheumatol. 2023 Jul; 5(7):e413-e421. PMID: 38251552

Allard-Chamard H, Kaneko N, Bertocchi A, Sun N, Boucau J, Kuo HH, Farmer JR, Perugino C, Mahajan VS, Murphy SJH, Premo K, Diefenbach T, Ghebremichael M, Yuen G, Kotta A, Akman Z, Lichterfeld M, Walker BD, Yu XG, Moriyama M, Maehara T, Nakamura S, Stone JH, Padera RF, Pillai S. Extrafollicular IgD-CD27-CXCR5-CD11c- DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19. Cell Rep. 2023 Jun 27; 42(6):112630. PMID: 37300833; PMCID: PMC10227203; DOI: 10.1016/j.celrep.2023.112630;

Balaban DT, Hutto SK, Panzarini BP, O'Shea A, Varma A, Jones PS, Chwalisz BK, Stone JH, Venna N. Treatment of IgG4-related disease-associated hypertrophic pachymeningitis with intrathecal rituximab: a case report. Front Neurol. 2023; 14:1189778. PMID: 37292126; PMCID: PMC10244657; DOI: 10.3389/fneur.2023.1189778;

Wallace ZS, Miles G, Smolkina E, Petruski-Ivleva N, Madziva D, Cook C, Fu X, Zhang Y, Stone JH, Choi HK. Incidence, prevalence and mortality of IgG4-related disease in the USA: a claims-based analysis of commercially insured adults. Ann Rheum Dis. 2023 Jul; 82(7):957-962. PMID: 37137671

Gill T, Putman M, Sattui SE, Hamdulay S, Conway R, Liew DFL, Sharma A, Stone JH, Mackie SL, Mehta P. Giant cell arteritis can occur in people of colour. Lancet Rheumatol. 2023 Apr; 5(4):e175-e177. PMID: 38251515

Matza MA, Dagincourt N, Mohan SV, Pavlov A, Han J, Stone JH, Unizony SH. Outcomes during and after long-term tocilizumab treatment in patients with giant cell arteritis. RMD Open. 2023 Apr; 9(2). PMID: 37024237; PMCID: PMC10083869; DOI: 10.1136/rmdopen-2022-002923;

Berti A, Hillion S, Konig MF, Moura MC, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D. Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol. 2023 May; 75(5):736-747. PMID: 36281741

Casal Moura M, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U. Activation of a Latent Epitope Causing Differential Binding of Antineutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis Rheumatol. 2023 May; 75(5):748-759. PMID: 36515151

Tanaka Y, Stone JH. Perspectives on current and emerging therapies for immunoglobulin G4-related disease. Mod Rheumatol. 2023 Mar 02; 33(2):229-236. PMID: 36408992

Casal Moura M, Deng Z, Brooks SR, Tew W, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Prunotto M, Grayson PC, Specks U. Risk of relapse of ANCA-associated vasculitis among patients homozygous for the proteinase 3 gene Val119Ile polymorphism. RMD Open. 2023 Mar; 9(1). PMID: 36990659; PMCID: PMC10069578; DOI: 10.1136/rmdopen-2022-002935;

Patel NJ, Jayne DRW, Merkel PA, Bekker P, Zhang Y, Yue H, Stone JH. Glucocorticoid Toxicity Index scores by domain in patients with antineutrophil cytoplasmic antibody-associated vasculitis treated with avacopan versus standard prednisone taper: post-hoc analysis of data from the ADVOCATE trial. Lancet Rheumatol. 2023 Mar; 5(3):e130-e138. PMID: 38251609

Odler B, Riedl R, Gauckler P, Shin JI, Leierer J, Merkel PA, St Clair W, Fervenza F, Geetha D, Monach P, Jayne D, Smith RM, Rosenkranz A, Specks U, Stone JH, Kronbichler A. Risk factors for serious infections in ANCA-associated vasculitis. Ann Rheum Dis. 2023 May; 82(5):681-687. PMID: 36702528; PMCID: PMC10176387; DOI: 10.1136/ard-2022-223401;

Mullins J, Stone J, Chopra A. Delayed presentation of fat embolism syndrome following elective total hip arthroplasty. BMJ Case Rep. 2022 Dec 09; 15(12). PMID: 36593634; PMCID: PMC9743280; DOI: 10.1136/bcr-2022-251348;

Stone JH, McDowell PJ, Jayne DRW, Merkel PA, Robson J, Patel NJ, Zhang Y, Yue H, Bekker P, Heaney LG. Corrigendum to The Glucocorticoid Toxicity Index: Measuring Change in Glucocorticoid Toxicity Over Time [Seminars in Arthritis and Rheumatism Volume 55, 152010]. Semin Arthritis Rheum. 2023 Feb; 58:152124. PMID: 36473338

Baker MC, Cook C, Fu X, Perugino CA, Stone JH, Wallace ZS. The Positive Predictive Value of a Very High Serum IgG4 Concentration for the Diagnosis of IgG4-Related Disease. J Rheumatol. 2023 Mar; 50(3):408-412. PMID: 36319016

Cochran RL, Brideau HR, Wu MY, Stone JH, Wallace ZS, Little BP. Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease. Radiol Case Rep. 2022 Dec; 17(12):4924-4927. PMID: 36299866

Jayne D, Stone JH, Rapalino O, Stone JR. Case 28-2022: A 59-Year-Old Man with Headache and Progressive Neurologic Dysfunction. N Engl J Med. 2022 Sep 15; 387(11):1022-1032. PMID: 36103417

Kaneko N, Chen H, Perugino CA, Maehara T, Munemura R, Yokomizo S, Sameshima J, Diefenbach TJ, Premo KR, Chinju A, Miyahara Y, Sakamoto M, Moriyama M, Stone JH, Nakamura S, Pillai S. Cytotoxic CD8+ T cells may be drivers of tissue destruction in Sjögren's syndrome. Sci Rep. 2022 Sep 14; 12(1):15427. PMID: 36104369

Gamerith G, Mildner F, Merkel PA, Harris K, Cooney L, Lim N, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Fervenza FC, Monach P, Ytterberg SR, Geetha D, Amann A, Wolf D, Specks U, Stone JH, Kronbichler A. Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission. Ann Rheum Dis. 2023 Feb; 82(2):253-261. PMID: 35973802

Wiebe E, Huscher D, Schaumburg D, Palmowski A, Hermann S, Buttgereit T, Biesen R, Burmester GR, Palmowski Y, Boers M, Stone JH, Dejaco C, Buttgereit F. Optimising both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease. Ann Rheum Dis. 2022 Aug 11; 81(9):1313-1322. PMID: 35680387

Stone JH, Spotswood H, Unizony SH, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Spiera R, Bao M. New-onset versus relapsing giant cell arteritis treated with tocilizumab: 3-year results from a randomized controlled trial and extension. Rheumatology (Oxford). 2022 Jul 06; 61(7):2915-2922. PMID: 34718434

McDermott G, Fu X, Cook C, Ahola C, Doliner B, Hanberg J, Stone JH, Choi HK, Zhang Y, Wallace ZS. The effect of achieving serological remission on subsequent risk of relapse, end-stage renal disease and mortality in ANCA-associated vasculitis: a target trial emulation study. Ann Rheum Dis. 2022 Oct; 81(10):1438-1445. PMID: 35697489

Munemura R, Maehara T, Murakami Y, Koga R, Aoyagi R, Kaneko N, Doi A, Perugino CA, Della-Torre E, Saeki T, Sato Y, Yamamoto H, Kiyoshima T, Stone JH, Pillai S, Nakamura S. Distinct disease-specific Tfh cell populations in 2 different fibrotic diseases: IgG4-related disease and Kimura disease. J Allergy Clin Immunol. 2022 Aug; 150(2):440-455.e17. PMID: 35568079

Tasoudis PT, Arvaniti CK, Adamou AT, Belios I, Stone JH, Horick N, Sagris D, Dalekos GN, Ntaios G. Interleukin-6 inhibitors reduce mortality in coronavirus disease-2019: An individual patient data meta-analysis from randomized controlled trials. Eur J Intern Med. 2022 Jul; 101:41-48. PMID: 35422374

Gorelik M, Chung SA, Ardalan K, Binstadt BA, Friedman K, Hayward K, Imundo LF, Lapidus SK, Kim S, Son MB, Sule S, Tremoulet AH, Van Mater H, Yildirim-Toruner C, Langford CA, Maz M, Abril A, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Merkel PA, Rhee RL, Seo P, Stone JH, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot M, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Kawasaki Disease. Arthritis Care Res (Hoboken). 2022 Apr; 74(4):538-548. PMID: 35257507

McDowell PJ, Stone JH, Zhang Y, Honeyford K, Dunn L, Logan RJ, McGarvey LPA, Butler CA, Heaney LG. Glucocorticoid toxicity reduction with mepolizumab using the Glucocorticoid Toxicity Index. Eur Respir J. 2022 Jan; 59(1). PMID: 34210787

Liang Y, Zeng FAP, Sheriff T, Wilson A, Bilgic A, Feng G, Stone JH, Murrell DF. Evaluation of the toxicity of glucocorticoids in patients with autoimmune blistering disease using the Glucocorticoid Toxicity Index: A cohort study. JAAD Int. 2022 Mar; 6:68-76. PMID: 35059661

Patel NJ, Fu X, Zhang Y, Unizony SH, Wallace ZS, Choi HK, Stone JH. The Effects of Treatment on Body Mass Index in Giant Cell Arteritis: A Post Hoc Analysis of the GiACTA Trial. Rheumatol Ther. 2022 Apr; 9(2):497-508. PMID: 34954809

Matza MA, Perugino CA, Harvey L, Fernandes AD, Wallace ZS, Liu H, Allard-Chamard H, Pillai S, Stone JH. Abatacept in IgG4-related disease: a prospective, open-label, single-arm, single-centre, proof-of-concept study. Lancet Rheumatol. 2022 Feb; 4(2):e105-e112. PMID: 35425928

Berti A, Hillion S, Hummel AM, Son YM, Chriti N, Peikert T, Carmona EM, Abdulahad WH, Heeringa P, Harris KM, St Clair EW, Brunetta P, Fervenza FC, Langford CA, Kallenberg CG, Merkel PA, Monach PA, Seo P, Spiera RF, Stone JH, Grandi G, Sun J, Pers JO, Specks U, Cornec D. Circulating autoreactive proteinase 3+ B cells and tolerance checkpoints in ANCA-associated vasculitis. JCI Insight. 2021 Nov 22; 6(22). PMID: 34618687

Monach PA, Warner RL, Lew R, Tómasson G, Specks U, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CGM, Langford CA, Seo P, St Clair EW, Spiera R, Johnson KJ, Merkel PA. Serum Biomarkers of Disease Activity in Longitudinal Assessment of Patients with ANCA-Associated Vasculitis. ACR Open Rheumatol. 2022 Feb; 4(2):168-176.View Related Profiles.

Stone, John
Lew, Robert

PMID: 34792864; PMCID: PMC8843765; DOI: 10.1002/acr2.11366;

Löhr JM, Vujasinovic M, Rosendahl J, Stone JH, Beuers U. IgG4-related diseases of the digestive tract. Nat Rev Gastroenterol Hepatol. 2022 Mar; 19(3):185-197. PMID: 34750548

Wallwork R, Perugino CA, Fu X, Harkness T, Zhang Y, Choi HK, Stone JH, Wallace ZS. The association of smoking with immunoglobulin G4-related disease: a case-control study. Rheumatology (Oxford). 2021 Nov 03; 60(11):5310-5317. PMID: 33751033

Rovati L, Kaneko N, Pedica F, Monno A, Maehara T, Perugino C, Lanzillotta M, Pecetta S, Stone JH, Doglioni C, Manfredi AA, Pillai S, Della-Torre E. Mer tyrosine kinase as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease. Rheumatology (Oxford). 2021 Oct 02; 60(10):4929-4941. PMID: 33512463

Cook C, Jorge A, Fu X, Niles J, Jeyabalan A, Zonozi R, Stone JH, Zhang Y, Choi HK, Wallace ZS. Association of renal transplantation with reduced risk of myocardial infarction and ischemic stroke in ANCA-associated vasculitis: An observational cohort study. Semin Arthritis Rheum. 2021 Dec; 51(6):1180-1185. PMID: 34600217

Shankar-Hari M, Vale CL, Godolphin PJ, Fisher D, Higgins JPT, Spiga F, Savovic J, Tierney J, Baron G, Benbenishty JS, Berry LR, Broman N, Cavalcanti AB, Colman R, De Buyser SL, Derde LPG, Domingo P, Omar SF, Fernandez-Cruz A, Feuth T, Garcia F, Garcia-Vicuna R, Gonzalez-Alvaro I, Gordon AC, Haynes R, Hermine O, Horby PW, Horick NK, Kumar K, Lambrecht BN, Landray MJ, Leal L, Lederer DJ, Lorenzi E, Mariette X, Merchante N, Misnan NA, Mohan SV, Nivens MC, Oksi J, Perez-Molina JA, Pizov R, Porcher R, Postma S, Rajasuriar R, Ramanan AV, Ravaud P, Reid PD, Rutgers A, Sancho-Lopez A, Seto TB, Sivapalasingam S, Soin AS, Staplin N, Stone JH, Strohbehn GW, Sunden-Cullberg J, Torre-Cisneros J, Tsai LW, van Hoogstraten H, van Meerten T, Veiga VC, Westerweel PE, Murthy S, Diaz JV, Marshall JC, Sterne JAC. Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis. JAMA. 2021 Aug 10; 326(6):499-518. PMID: 34228774

Chung SA, Gorelik M, Langford CA, Maz M, Abril A, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot M, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Polyarteritis Nodosa. Arthritis Care Res (Hoboken). 2021 Aug; 73(8):1061-1070. PMID: 34235889

Maz M, Chung SA, Abril A, Langford CA, Gorelik M, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot MA, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis. Arthritis Rheumatol. 2021 Aug; 73(8):1349-1365. PMID: 34235884

Chung SA, Gorelik M, Langford CA, Maz M, Abril A, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot M, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Polyarteritis Nodosa. Arthritis Rheumatol. 2021 Aug; 73(8):1384-1393. PMID: 34235883

Chung SA, Langford CA, Maz M, Abril A, Gorelik M, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot MA, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Care Res (Hoboken). 2021 Aug; 73(8):1088-1105. PMID: 34235880

Chung SA, Langford CA, Maz M, Abril A, Gorelik M, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot MA, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol. 2021 Aug; 73(8):1366-1383. PMID: 34235894

Maz M, Chung SA, Abril A, Langford CA, Gorelik M, Guyatt G, Archer AM, Conn DL, Full KA, Grayson PC, Ibarra MF, Imundo LF, Kim S, Merkel PA, Rhee RL, Seo P, Stone JH, Sule S, Sundel RP, Vitobaldi OI, Warner A, Byram K, Dua AB, Husainat N, James KE, Kalot MA, Lin YC, Springer JM, Turgunbaev M, Villa-Forte A, Turner AS, Mustafa RA. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis. Arthritis Care Res (Hoboken). 2021 Aug; 73(8):1071-1087. PMID: 34235871

Lanzillotta M, Della-Torre E, Wallace ZS, Stone JH, Karadag O, Fernández-Codina A, Arcidiacono PG, Falconi M, Dagna L, Capurso G. Efficacy and safety of rituximab for IgG4-related pancreato-biliary disease: A systematic review and meta-analysis. Pancreatology. 2021 Oct; 21(7):1395-1401. PMID: 34244040

Meyerowitz EA, Sen P, Schoenfeld SR, Neilan TG, Frigault MJ, Stone JH, Kim AY, Mansour MK. Immunomodulation as Treatment for Severe Coronavirus Disease 2019: A Systematic Review of Current Modalities and Future Directions. Clin Infect Dis. 2021 Jun 15; 72(12):e1130-e1143. PMID: 33216852

Unizony SH, Bao M, Han J, Luder Y, Pavlov A, Stone JH. Treatment failure in giant cell arteritis. Ann Rheum Dis. 2021 Nov; 80(11):1467-1474. PMID: 34049857

Jarrell JA, Baker MC, Perugino CA, Liu H, Bloom MS, Maehara T, Wong HH, Lanz TV, Adamska JZ, Kongpachith S, Sokolove J, Stone JH, Pillai SS, Robinson WH. Neutralizing anti-IL-1 receptor antagonist autoantibodies induce inflammatory and fibrotic mediators in IgG4-related disease. J Allergy Clin Immunol. 2022 Jan; 149(1):358-368. PMID: 33974929

Stone JH, Han J, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Spiera R, Unizony SH, Bao M. Long-term effect of tocilizumab in patients with giant cell arteritis: open-label extension phase of the Giant Cell Arteritis Actemra (GiACTA) trial. Lancet Rheumatol. 2021 May; 3(5):e328-e336. PMID: 38279390

Spiera R, Unizony SH, Bao M, Luder Y, Han J, Pavlov A, Stone JH. Tocilizumab vs placebo for the treatment of giant cell arteritis with polymyalgia rheumatica symptoms, cranial symptoms or both in a randomized trial. Semin Arthritis Rheum. 2021 Apr; 51(2):469-476. PMID: 33784598

Plichta DR, Somani J, Pichaud M, Wallace ZS, Fernandes AD, Perugino CA, Lähdesmäki H, Stone JH, Vlamakis H, Chung DC, Khanna D, Pillai S, Xavier RJ. Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis. Genome Med. 2021 Feb 28; 13(1):35. PMID: 33648559

Wallace ZS, Yun H, Curtis JR, Chen L, Stone JH, Choi HK. ANCA-associated Vasculitis Management in the United States: Data From the Rheumatology Informatics System for Effectiveness (RISE) Registry. J Rheumatol. 2021 Jul; 48(7):1060-1064. PMID: 33526622

Unizony S, McCulley TJ, Spiera R, Pei J, Sidiropoulos PN, Best JH, Birchwood C, Pavlov A, Stone JH. Clinical outcomes of patients with giant cell arteritis treated with tocilizumab in real-world clinical practice: decreased incidence of new visual manifestations. Arthritis Res Ther. 2021 Jan 06; 23(1):8. PMID: 33407817

Wang L, Miloslavsky E, Stone JH, Choi HK, Zhou L, Wallace ZS. Topic modeling to characterize the natural history of ANCA-Associated vasculitis from clinical notes: A proof of concept study. Semin Arthritis Rheum. 2021 Feb; 51(1):150-157. PMID: 33383291

Cortazar FB, Rhee EP, Gupta S, Sakhuja R, Stone JH, Colvin RB. Case 34-2020: A 74-Year-Old Man with Chronic Kidney Disease. N Engl J Med. 2020 Oct 29; 383(18):1768-1778. PMID: 33113299

Stone JH, Frigault MJ, Serling-Boyd NJ, Fernandes AD, Harvey L, Foulkes AS, Horick NK, Healy BC, Shah R, Bensaci AM, Woolley AE, Nikiforow S, Lin N, Sagar M, Schrager H, Huckins DS, Axelrod M, Pincus MD, Fleisher J, Sacks CA, Dougan M, North CM, Halvorsen YD, Thurber TK, Dagher Z, Scherer A, Wallwork RS, Kim AY, Schoenfeld S, Sen P, Neilan TG, Perugino CA, Unizony SH, Collier DS, Matza MA, Yinh JM, Bowman KA, Meyerowitz E, Zafar A, Drobni ZD, Bolster MB, Kohler M, D'Silva KM, Dau J, Lockwood MM, Cubbison C, Weber BN, Mansour MK. Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. N Engl J Med. 2020 12 10; 383(24):2333-2344.View Related Profiles.

Moraco, Andrew
Stone, John
Tedrow, John
Fleisher, Jorge
Sagar, Manish
Lin, Nina
Lacamera, Peter

PMID: 33085857; PMCID: PMC7646626; DOI: 10.1056/NEJMoa2028836;

Liu H, Wallace ZS, Harvey L, Crotty R, Wu CL, Deshpande V, O'Shea A, Harisinghani M, Ghebremichael M, Nehra A, Stone JH, Perugino CA. Prostate and pancreas involvement are linked in IgG4-related disease. Semin Arthritis Rheum. 2020 Dec; 50(6):1245-1251. PMID: 33065419

Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U. Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis. Front Immunol. 2020; 11:2053. PMID: 33013868

Wallace ZS, Fu X, Harkness T, Stone JH, Zhang Y, Choi H. All-cause and cause-specific mortality in ANCA-associated vasculitis: overall and according to ANCA type. Rheumatology (Oxford). 2020 Sep 01; 59(9):2308-2315. PMID: 31846030

McDowell PJ, Stone JH, Zhang Y, Honeyford K, Dunn L, Logan RJ, Butler CA, McGarvey LPA, Heaney LG. Quantification of Glucocorticoid-Associated Morbidity in Severe Asthma Using the Glucocorticoid Toxicity Index. J Allergy Clin Immunol Pract. 2021 Jan; 9(1):365-372.e5. PMID: 32882446

Schmidkonz C, Rauber S, Atzinger A, Agarwal R, Götz TI, Soare A, Cordes M, Prante O, Bergmann C, Kleyer A, Ritt P, Maschauer S, Hennig P, Toms J, Köhner M, Manger B, Stone JH, Haberkorn U, Baeuerle T, Distler JHW, Agaimy A, Kuwert T, Schett G, Ramming A. Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging. Ann Rheum Dis. 2020 Nov; 79(11):1485-1491. PMID: 32719042

McDermott G, Fu X, Stone JH, Wallwork R, Zhang Y, Choi HK, Wallace ZS. Association of Cigarette Smoking With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. JAMA Intern Med. 2020 Jun 01; 180(6):870-876. PMID: 32282021

Perugino CA, Kaneko N, Maehara T, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Della-Torre E, Murphy SJH, Ghebremichael M, Wallace ZS, Bolster MB, Harvey LM, Mylvaganam G, Tuncay Y, Liang L, Montesi SB, Zhang X, Tinju A, Mochizuki K, Munemura R, Sakamoto M, Moriyama M, Nakamura S, Yosef N, Stone JH, Pillai S. CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease. J Allergy Clin Immunol. 2021 Jan; 147(1):368-382. PMID: 32485263

Maehara T, Kaneko N, Perugino CA, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Murphy SJ, Ghebremichael M, Fox D, Payne AS, Lafyatis R, Stone JH, Khanna D, Pillai S. Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis. J Clin Invest. 2020 05 01; 130(5):2451-2464.View Related Profiles.

Stone, John
Lafyatis, Robert

PMID: 31990684; PMCID: PMC7190971; DOI: 10.1172/JCI131700;

Sobrin L, Stone JH, Huang AJ, Niles JL, Nazarian RM. Case 14-2020: A 37-Year-Old Man with Joint Pain and Eye Redness. N Engl J Med. 2020 Apr 30; 382(18):1750-1758. PMID: 32348648

Harkness T, Fu X, Zhang Y, Choi HK, Stone JH, Blumenthal KG, Wallace ZS. Immunoglobulin G and immunoglobulin G subclass concentrations differ according to sex and race. Ann Allergy Asthma Immunol. 2020 Aug; 125(2):190-195.e2. PMID: 32224206

Wallace ZS, Stone JH. Personalized Medicine in ANCA-Associated Vasculitis ANCA Specificity as the Guide? Front Immunol. 2019; 10:2855. PMID: 31867013

Wallace ZS, Naden RP, Chari S, Choi HK, Della-Torre E, Dicaire JF, Hart PA, Inoue D, Kawano M, Khosroshahi A, Lanzillotta M, Okazaki K, Perugino CA, Sharma A, Saeki T, Schleinitz N, Takahashi N, Umehara H, Zen Y, Stone JH. The 2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease. Ann Rheum Dis. 2020 Jan; 79(1):77-87. PMID: 31796497

Wallace ZS, Naden RP, Chari S, Choi H, Della-Torre E, Dicaire JF, Hart PA, Inoue D, Kawano M, Khosroshahi A, Kubota K, Lanzillotta M, Okazaki K, Perugino CA, Sharma A, Saeki T, Sekiguchi H, Schleinitz N, Stone JR, Takahashi N, Umehara H, Webster G, Zen Y, Stone JH. The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease. Arthritis Rheumatol. 2020 Jan; 72(1):7-19. PMID: 31793250

Kronbichler A, Leierer J, Shin JI, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CGM, St Clair EW, Brunetta P, Fervenza FC, Geetha D, Keogh KA, Monach PA, Ytterberg SR, Mayer G, Specks U, Stone JH. Association of Pulmonary Hemorrhage, Positive Proteinase 3, and Urinary Red Blood Cell Casts With Venous Thromboembolism in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol. 2019 11; 71(11):1888-1893.View Related Profiles.

Year	Publications
2005	2
2007	2
2008	1
2011	1
2012	3
2013	7
2014	8
2015	14
2016	17
2017	13
2018	9
2019	15
2020	13
2021	24
2022	16
2023	19
2024	15
2025	2