Jerome Mertz | Profiles RNS

Jerome Mertz, PhD

Professor

Boston University College of Engineering

Biomedical Engineering

PhD, University of California, Santa Barbara
BA, Princeton University

Websites

	Google Scholar
	ResearchGate
	Biomicroscopy Lab
	BU Center for Neuroscience

ORCID : 0000-0002-6343-9155

Jerome Mertz, PhD, is professor of Biomedical Engineering and director of the Biomicroscopy Laboratory at Boston University. Prior to joining Boston University, he was a CNRS researcher at the École Supérieure de Physique et de Chimie Industrielles in Paris. He specializes in the development of novel microscopy techniques for biological imaging

Professor Mertz’s lab focuses on the development and applications of novel optical microscopy techniques for biomedical imaging. Some specific topics include imaging through complex media, imaging through a single optical fiber, and oblique back-illumination microscopy.

BU Research
NIH RePORTER Research

Multi-layer neuronal imaging with reverberation multiphoton microscopy
03/15/2020 - 12/31/2025 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS116139-05

Ultrafast high-contrast voltage imaging in freely moving animals
03/15/2022 - 02/28/2025 (PI)
NIH/National Institute of Neurological Disorders & Stroke
1R34NS127098-01

Fast, large-scale neuronal imaging with multi-z confocal microscopy
02/01/2020 - 11/30/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB029171-04

Speckle-free phase-contrast ultrasound imaging
09/15/2019 - 08/31/2022 (PI)
NIH/National Institute of General Medical Sciences
5R21GM134216-02

Retinal/choroidal imaging with transcranial back-illumination
09/01/2018 - 08/31/2021 (PI)
NIH/National Eye Institute
5R21EY029486-02

Development of label-free computational flow cytometry for high-throughput micro-organism classification
06/01/2018 - 03/31/2021 (PI)
NIH/National Institute of General Medical Sciences
5R21GM128020-02

High dynamic range multiphoton microscopy for large-scale imaging
09/30/2016 - 07/31/2020 (Multi-PI)
PI: Jerome Mertz, PhD
NIH/National Eye Institute
5R21EY027549-02

UNS: Fluorescence light-field imaging with a lensless flexible fiber bundle
06/01/2015 - 11/30/2019 (PI)
National Science Foundation
CBET-1508988

High Resolution Phase Contrast Endoscopy
12/15/2013 - 11/30/2019 (PI)
NIH/National Cancer Institute
5R01CA182939-04

Advanced laser scanning confocal microscope for multiple users
08/01/2018 - 07/31/2019 (PI)
NIH/Office of the Director
1S10OD024993-01

Showing 10 of 26 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2024	Multi-Layer Neuronal Imaging with Reverberation Multiphoton Microscopy	5R01NS116139-05
2023	Multi-layer neuronal imaging with reverberation multiphoton microscopy	5R01NS116139-04
2023	Fast, large-scale neuronal imaging with multi-z confocal microscopy	5R01EB029171-04
2022	Ultrafast high-contrast voltage imaging in freely moving animals	1R34NS127098-01
2022	Multi-layer neuronal imaging with reverberation multiphoton microscopy	5R01NS116139-03
2022	Fast, large-scale neuronal imaging with multi-z confocal microscopy	5R01EB029171-03
2021	Multi-layer neuronal imaging with reverberation multiphoton microscopy	5R01NS116139-02
2021	Fast, large-scale neuronal imaging with multi-z confocal microscopy	5R01EB029171-02
2020	Multi-layer neuronal imaging with reverberation multiphoton microscopy	1R01NS116139-01
2020	Fast, large-scale neuronal imaging with multi-z confocal microscopy	1R01EB029171-01

Showing 10 of 42 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Khetan N, Mertz J. Plane wave compounding with adaptive joint coherence factor weighting. Ultrasonics. 2025 Jan 22; 149:107573. PMID: 39893756

Xiao S, Cunningham WJ, Kondabolu K, Lowet E, Moya MV, Mount RA, Ravasio C, Bortz E, Shaw D, Economo MN, Han X, Mertz J. Large-scale deep tissue voltage imaging with targeted-illumination confocal microscopy. Nat Methods. 2024 Jun; 21(6):1094-1102.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 38840033; PMCID: PMC11500676; DOI: 10.1038/s41592-024-02275-w;

Hu G, Greene J, Zhu J, Yang Q, Zheng S, Li Y, Alido J, Guo R, Mertz J, Tian L. HiLo microscopy with caustic illumination. Biomed Opt Express. 2024 Jul 01; 15(7):4101-4110. PMID: 39022539; PMCID: PMC11249696; DOI: 10.1364/BOE.527264;

Zheng S, Koyama M, Mertz J. Multiplane HiLo microscopy with speckle illumination and non-local means denoising. J Biomed Opt. 2023 Nov; 28(11):116502. PMID: 38078150; PMCID: PMC10704089; DOI: 10.1117/1.JBO.28.11.116502;

Zhao B, Mertz J. Resolution enhancement with deblurring by pixel reassignment. Adv Photonics. 2023; 5(6). PMID: 38884067; PMCID: PMC11178354; DOI: 10.1117/1.ap.5.6.066004;

Zhao B, Mertz J. Resolution enhancement with deblurring by pixel reassignment (DPR). bioRxiv. 2023 Sep 16. PMID: 37546886; PMCID: PMC10402078; DOI: 10.1101/2023.07.24.550382;

Mahler S, Huang YX, Liang M, Avalos A, Tyszka JM, Mertz J, Yang C. Assessing depth sensitivity in laser interferometry speckle visibility spectroscopy (iSVS) through source-to-detector distance variation and cerebral blood flow monitoring in humans and rabbits. Biomed Opt Express. 2023 Sep 01; 14(9):4964-4978. PMID: 37791277; PMCID: PMC10545208; DOI: 10.1364/BOE.498815;

Weber TD, Moya MV, Kiliç K, Mertz J, Economo MN. High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations. Nat Neurosci. 2023 Sep; 26(9):1642-1650.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37604887; PMCID: PMC11209746; DOI: 10.1038/s41593-023-01408-2;

Lowet E, Sheehan DJ, Chialva U, De Oliveira Pena R, Mount RA, Xiao S, Zhou SL, Tseng HA, Gritton H, Shroff S, Kondabolu K, Cheung C, Wang Y, Piatkevich KD, Boyden ES, Mertz J, Hasselmo ME, Rotstein HG, Han X. Theta and gamma rhythmic coding through two spike output modes in the hippocampus during spatial navigation. Cell Rep. 2023 Aug 29; 42(8):112906.View Related Profiles.

Mertz, Jerome
Hasselmo, Michael

PMID: 37540599; PMCID: PMC10530698; DOI: 10.1016/j.celrep.2023.112906;

Xiao S, Cunningham WJ, Kondabolu K, Lowet E, Moya MV, Mount R, Ravasio C, Economo MN, Han X, Mertz J. Large-scale deep tissue voltage imaging with targeted illumination confocal microscopy. bioRxiv. 2023 Jul 21.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37502929; PMCID: PMC10370169; DOI: 10.1101/2023.07.21.548930;

Showing 10 of 142 results. Show More

Xiao S, Giblin JT, Boas DA, Mertz J. High-throughput deep tissue two-photon microscopy at kilohertz frame rates. Optica. 2023 Jun 20; 10(6):763-769.View Related Profiles.

Boas, David
Mertz, Jerome

PMID: 38882052; PMCID: PMC11178336; DOI: 10.1364/optica.487272;

Zhao B, Koyama M, Mertz J. High-resolution multi-z confocal microscopy with a diffractive optical element. Biomed Opt Express. 2023 Jun 01; 14(6):3057-3071. PMID: 37342696; PMCID: PMC10278611; DOI: 10.1364/BOE.491538;

Abdelfattah AS, Zheng J, Singh A, Huang YC, Reep D, Tsegaye G, Tsang A, Arthur BJ, Rehorova M, Olson CVL, Shuai Y, Zhang L, Fu TM, Milkie DE, Moya MV, Weber TD, Lemire AL, Baker CA, Falco N, Zheng Q, Grimm JB, Yip MC, Walpita D, Chase M, Campagnola L, Murphy GJ, Wong AM, Forest CR, Mertz J, Economo MN, Turner GC, Koyama M, Lin BJ, Betzig E, Novak O, Lavis LD, Svoboda K, Korff W, Chen TW, Schreiter ER, Hasseman JP, Kolb I. Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator. Neuron. 2023 May 17; 111(10):1547-1563.e9.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37015225; PMCID: PMC10280807; DOI: 10.1016/j.neuron.2023.03.009;

Zheng S, Mertz J. Correcting sampling bias in speckle contrast imaging. Opt Lett. 2022 Dec 15; 47(24):6333-6336. PMID: 36538431; PMCID: PMC9801309; DOI: 10.1364/OL.474604;

Zheng S, Mertz J. Direct characterization of tissue dynamics with laser speckle contrast imaging. Biomed Opt Express. 2022 Aug 01; 13(8):4118-4133. PMID: 36032565; PMCID: PMC9408238; DOI: 10.1364/BOE.462913;

Sheinman M, Erramilli S, Ziegler L, Hong MK, Mertz J. Flatfield ultrafast imaging with single-shot non-synchronous array photography. Opt Lett. 2022 Feb 01; 47(3):577-580.View Related Profiles.

Mertz, Jerome
Ziegler, Lawrence

PMID: 35103680

Xiao S, Davison I, Mertz J. Scan multiplier unit for ultrafast laser scanning beyond the inertia limit. Optica. 2021 Nov 20; 8(11):1403-1404. PMID: 37275678; PMCID: PMC10237152; DOI: 10.1364/optica.445254;

Xiao S, Lowet E, Gritton HJ, Fabris P, Wang Y, Sherman J, Mount RA, Tseng HA, Man HY, Straub C, Piatkevich KD, Boyden ES, Mertz J, Han X. Large-scale voltage imaging in behaving mice using targeted illumination. iScience. 2021 Nov 19; 24(11):103263.View Related Profiles.

Man, Hengye
Mertz, Jerome
Han, Xue

PMID: 34761183; PMCID: PMC8567393; DOI: 10.1016/j.isci.2021.103263;

Zheng S, Xiao S, Kretsge L, Cruz-Martín A, Mertz J. Depth resolution in multifocus laser speckle contrast imaging. Opt Lett. 2021 Oct 01; 46(19):5059-5062.View Related Profiles.

Mertz, Jerome
Kretsge, Lisa

PMID: 34598268; PMCID: PMC9801310; DOI: 10.1364/OL.436334;

Xiao S, Zheng S, Mertz J. High-speed multifocus phase imaging in thick tissue. Biomed Opt Express. 2021 Sep 01; 12(9):5782-5792. PMID: 34692215; PMCID: PMC8515987; DOI: 10.1364/BOE.436247;

Weber TD, Khetan N, Yang R, Mertz J. Ultrasound differential phase contrast using backscattering and the memory effect. Appl Phys Lett. 2021 Mar 22; 118(12):124103. PMID: 33785963; PMCID: PMC8004294; DOI: 10.1063/5.0048071;

Tsang JM, Gritton HJ, Das SL, Weber TD, Chen CS, Han X, Mertz J. Fast, multiplane line-scan confocal microscopy using axially distributed slits. Biomed Opt Express. 2021 Mar 01; 12(3):1339-1350.View Related Profiles.

Chen, Christopher
Mertz, Jerome
Han, Xue

PMID: 33796357; PMCID: PMC7984773; DOI: 10.1364/BOE.417286;

Chamling X, Kallman A, Fang W, Berlinicke CA, Mertz JL, Devkota P, Pantoja IEM, Smith MD, Ji Z, Chang C, Kaushik A, Chen L, Whartenby KA, Calabresi PA, Mao HQ, Ji H, Wang TH, Zack DJ. Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells. Nat Commun. 2021 01 28; 12(1):652. PMID: 33510160; PMCID: PMC7844020; DOI: 10.1038/s41467-021-20892-3;

Weber D, Moya MV, Mertz J, Economo MN. High-speed, multi-Z confocal microscopy for voltage imaging in densely labeled neuronal populations. bioRxiv. 2021. View Publication

Mertz JL, Sun S, Yin B, Hu Y, Bhattacharya R, Bettenbaugh MJ, Yarema KJ, Zhang H. Comparison of Three Glycoproteomic Methods for the Analysis of the Secretome of CHO Cells Treated with 1,3,4-O-Bu3ManNAc. Bioengineering (Basel). 2020 Nov 10; 7(4). PMID: 33182731; PMCID: PMC7712478; DOI: 10.3390/bioengineering7040144;

Xiao S, Gritton H, Tseng HA, Zemel D, Han X, Mertz J. High-contrast multifocus microscopy with a single camera and z-splitter prism. Optica. 2020 Nov 20; 7(11):1477-1486.View Related Profiles.

Mertz, Jerome
Han, Xue

PMID: 34532564; PMCID: PMC8443084; DOI: 10.1364/optica.404678;

Weber TD, Mertz J. In vivo corneal and lenticular microscopy with asymmetric fundus retroillumination. Biomed Opt Express. 2020 Jun 01; 11(6):3263-3273. PMID: 32637253; PMCID: PMC7316012; DOI: 10.1364/BOE.391815;

Beaulieu DR, Davison IG, Kiliç K, Bifano TG, Mertz J. Simultaneous multiplane imaging with reverberation two-photon microscopy. Nat Methods. 2020 03; 17(3):283-286. PMID: 32042186; PMCID: PMC8590882; DOI: 10.1038/s41592-019-0728-9;

Cheng X, Li Y, Mertz J, Sakadžic S, Devor A, Boas DA, Tian L. Development of a beam propagation method to simulate the point spread function degradation in scattering media. Opt Lett. 2019 Oct 15; 44(20):4989-4992.View Related Profiles.

Devor, Anna
Boas, David
Mertz, Jerome

PMID: 31613246; PMCID: PMC6889808; DOI: 10.1364/OL.44.004989;

Xiao S, Mertz J. Contrast improvement in two-photon microscopy with instantaneous differential aberration imaging. Biomed Opt Express. 2019 May 01; 10(5):2467-2477. PMID: 31143499; PMCID: PMC6524596; DOI: 10.1364/BOE.10.002467;

Badon A, Bensussen S, Gritton HJ, Awal MR, Gabel CV, Han X, Mertz J. Video-rate large-scale imaging with Multi-Z confocal microscopy. Optica. 2019 Apr 20; 6(4):389-395.View Related Profiles.

Gabel, Christopher
Mertz, Jerome
Awal, Mehraj
Han, Xue

PMID: 34504902; PMCID: PMC8425499; DOI: 10.1364/optica.6.000389;

Ba C, Shain WJ, Bifano TG, Mertz J. High-throughput label-free flow cytometry based on matched-filter compressive imaging. Biomed Opt Express. 2018 Dec 01; 9(12):6145-6153. PMID: 31065419; PMCID: PMC6491006; DOI: 10.1364/BOE.9.006145;

Weber TD, Mertz J. Non-mydriatic chorioretinal imaging in a transmission geometry and application to retinal oximetry. Biomed Opt Express. 2018 Aug 01; 9(8):3867-3882. PMID: 30338161; PMCID: PMC6191618; DOI: 10.1364/BOE.9.003867;

Xiao S, Tseng HA, Gritton H, Han X, Mertz J. Video-rate volumetric neuronal imaging using 3D targeted illumination. Sci Rep. 2018 05 21; 8(1):7921.View Related Profiles.

Mertz, Jerome
Han, Xue

PMID: 29784920; PMCID: PMC5962542; DOI: 10.1038/s41598-018-26240-8;

Ba C, Tsang JM, Mertz J. Fast hyperspectral phase and amplitude imaging in scattering tissue. Opt Lett. 2018 May 01; 43(9):2058-2061. PMID: 29714745; PMCID: PMC8328793; DOI: 10.1364/OL.43.002058;

Sentenac A, Mertz J. Unified description of three-dimensional optical diffraction microscopy: from transmission microscopy to optical coherence tomography: tutorial. J Opt Soc Am A Opt Image Sci Vis. 2018 May 01; 35(5):748-754. PMID: 29726491; DOI: 10.1364/JOSAA.35.000748;

Shain WJ, Vickers NA, Li J, Han X, Bifano T, Mertz J. Axial localization with modulated-illumination extended-depth-of-field microscopy. Biomed Opt Express. 2018 Apr 01; 9(4):1771-1782.View Related Profiles.

Mertz, Jerome
Han, Xue

PMID: 29675318; PMCID: PMC5905922; DOI: 10.1364/BOE.9.001771;

Xiao S, Tseng H, Gritton H, Han X, Mertz J. Video-rate volumetric imaging using 3D targeted illumination. Sci. Rep. 2018; 8:7921.

Shain WJ, Vickers NA, Negash A, Bifano T, Sentenac A, Mertz J. Dual fluorescence-absorption deconvolution applied to extended-depth-of-field microscopy. Opt Lett. 2017 Oct 15; 42(20):4183-4186. PMID: 29028043; DOI: 10.1364/OL.42.004183;

Yang R, Weber TD, Witkowski ED, Davison IG, Mertz J. Neuronal imaging with ultrahigh dynamic range multiphoton microscopy. Sci Rep. 2017 07 19; 7(1):5817.View Related Profiles.

Witkowski, Ellen
Mertz, Jerome

PMID: 28725020; PMCID: PMC5517475; DOI: 10.1038/s41598-017-06065-7;

Shain WJ, Vickers NA, Goldberg BB, Bifano T, Mertz J. Extended depth-of-field microscopy with a high-speed deformable mirror. Opt Lett. 2017 Mar 01; 42(5):995-998. PMID: 28248351; DOI: 10.1364/OL.42.000995;

Li J, Bifano TG, Mertz J. Widefield fluorescence microscopy with sensor-based conjugate adaptive optics using oblique back illumination. J Biomed Opt. 2016 12 01; 21(12):121504. PMID: 27653793; PMCID: PMC5039021; DOI: 10.1117/1.JBO.21.12.121504;

Ba C, Palmiere M, Ritt J, Mertz J. Dual-modality endomicroscopy with co-registered fluorescence and phase contrast. Biomed Opt Express. 2016 Sep 01; 7(9):3403-3411. PMID: 27699107; PMCID: PMC5030019; DOI: 10.1364/BOE.7.003403;

Barankov R, Baritaux JC, Mertz J. High-resolution 3D phase imaging using a partitioned detection aperture: a wave-optic analysis. J Opt Soc Am A Opt Image Sci Vis. 2015 Nov 01; 32(11):2123-35. PMID: 26560927; DOI: 10.1364/JOSAA.32.002123;

Paudel HP, Taranto J, Mertz J, Bifano T. Axial range of conjugate adaptive optics in two-photon microscopy: erratum. Opt Express. 2015 Oct 19; 23(21):27635. PMID: 26480425; DOI: 10.1364/OE.23.027635;

Paudel HP, Taranto J, Mertz J, Bifano T. Axial range of conjugate adaptive optics in two-photon microscopy. Opt Express. 2015 Aug 10; 23(16):20849-57. PMID: 26367938; PMCID: PMC5802239; DOI: 10.1364/OE.23.020849;

Mertz J, Cao H, Gigan S, Piestun R. Controlled light propagation through complex media introduction. Opt Express. 2015 May 18; 23(10):13587-8. PMID: 26074607; DOI: 10.1364/OE.23.013587;

Mertz J, Paudel H, Bifano TG. Field of view advantage of conjugate adaptive optics in microscopy applications. Appl Opt. 2015 Apr 10; 54(11):3498-506. PMID: 25967343; PMCID: PMC4629780; DOI: 10.1364/AO.54.003498;

Li J, Beaulieu DR, Paudel H, Barankov R, Bifano TG, Mertz J. Conjugate adaptive optics in widefield microscopy with an extended-source wavefront sensor. Optica. 2015; 2:682-688.

Barankov R, Mertz J. High-throughput imaging of self-luminous objects through a single optical fibre. Nat Commun. 2014 Nov 20; 5:5581. PMID: 25410902; PMCID: PMC4629809; DOI: 10.1038/ncomms6581;

Mertiri A, Altug H, Hong MK, Mehta P, Mertz J, Ziegler LD, Erramilli S. Nonlinear Midinfrared Photothermal Spectroscopy Using Zharov Splitting and Quantum Cascade Lasers. ACS Photonics. 2014 Aug 20; 1(8):696-702.View Related Profiles.

Mertz, Jerome
Ziegler, Lawrence

PMID: 25541620; PMCID: PMC4270413; DOI: 10.1021/ph500114h;

David Giese J, Ford TN, Mertz J. Fast volumetric phase-gradient imaging in thick samples. Opt Express. 2014 Jan 13; 22(1):1152-62. PMID: 24515075; PMCID: PMC3926542; DOI: 10.1364/OE.22.001152;

Mertz J, Gasecka A, Daradich A, Davison I, Coté D. Phase-gradient contrast in thick tissue with a scanning microscope. Biomed Opt Express. 2014 Feb 01; 5(2):407-16. PMID: 24575336; PMCID: PMC3920872; DOI: 10.1364/BOE.5.000407;

Giese JD, Ford TN, Mertz J. Fast volumetric imaging in thick samples. Opt. Express. 2014; 22:1152-62.
Mertz J, Gasecka A, Daradich A, Davison I, Coté D. Phase gradient contrast in thick tissue with a scanning microscope. Biomed. Opt. Express. 2014; 5:407-416.
Mertiri A, Altug H, Kong MK, Mehta P, Mertz J, Ziegler LD, Erramilli S. Nonlinear midifrared photothermal spectroscopy using Zharov splitting and quantum cascade lasers. ACS Photonics. 2014; 1:696-702.
Barankov R, Mertz J. High throughput imaging of self-luminous objects through a single fibre. Nat. Commun. 2014; 5:5581. View Publication

Barankov R, Mertz J. Single-exposure surface profilometry using partitioned aperture wavefront imaging. Opt Lett. 2013 Oct 01; 38(19):3961-4. PMID: 24081099; DOI: 10.1364/OL.38.003961;

Mertz J, Potma EO. Introduction to the Novel Techniques in Microscopy feature issue. Biomed Opt Express. 2013; 4(10):2207-8. PMID: 24156076; PMCID: PMC3799678; DOI: 10.1364/BOE.4.002207;

Paudel HP, Stockbridge C, Mertz J, Bifano T. Focusing polychromatic light through strongly scattering media. Opt Express. 2013 Jul 15; 21(14):17299-308. PMID: 23938576; DOI: 10.1364/OE.21.017299;

Ford TN, Mertz J. Video-rate imaging of microcirculation with single-exposure oblique back-illumination microscopy. J Biomed Opt. 2013 Jun; 18(6):066007. PMID: 23733023; PMCID: PMC3670618; DOI: 10.1117/1.JBO.18.6.066007;

Dong CY, So PT, Mertz J, Koenig K, Xu C, Campagnola P. Multiphoton microscopy: technical innovations, biological applications, and clinical diagnostics. J Biomed Opt. 2013 Mar; 18(3):031101. PMID: 23563896; DOI: 10.1117/1.JBO.18.3.031101;

Paudel HP, Stockbridge C, Mertz J, Bifano T. Focusing light through strongly scattering media. Opt. Express. 2013; 21:17299-308.

Ford TN, Chu KK, Mertz J. Phase-gradient microscopy in thick tissue with oblique back-illumination. Nat Methods. 2012 Dec; 9(12):1195-7. PMID: 23103879; PMCID: PMC8407656; DOI: 10.1038/nmeth.2219;

Parthasarathy AB, Chu KK, Ford TN, Mertz J. Quantitative phase imaging using a partitioned detection aperture. Opt Lett. 2012 Oct 01; 37(19):4062-4. PMID: 23027279; DOI: 10.1364/OL.37.004062;

Chu KK, Mertz J. Single-exposure complementary aperture phase microscopy with polarization encoding. Opt Lett. 2012 Sep 15; 37(18):3798-800. PMID: 23041863; DOI: 10.1364/ol.37.003798;

Mërtiri A, Jeys T, Liberman V, Hong MK, Mertz J, Altug H, Erramilli S. Mid-infrared photothermal heterodyne spectroscopy in a liquid crystal using a quantum cascade laser. Appl Phys Lett. 2012 Jul 23; 101(4):44101. PMID: 22912508; PMCID: PMC3416835; DOI: 10.1063/1.4737942;

Lillis KP, Kramer MA, Mertz J, Staley KJ, White JA. Pyramidal cells accumulate chloride at seizure onset. Neurobiol Dis. 2012 Sep; 47(3):358-66.View Related Profiles.

Mertz, Jerome
White, John

PMID: 22677032; PMCID: PMC3392473; DOI: 10.1016/j.nbd.2012.05.016;

Ford TN, Lim D, Mertz J. Fast optically sectioned fluorescence HiLo endomicroscopy. J Biomed Opt. 2012 Feb; 17(2):021105. PMID: 22463023; PMCID: PMC3382350; DOI: 10.1117/1.JBO.17.2.021105;

Chu KK, Mertz J. Single exposure complementary aperture phase microscopy with polarization encoding. Opt. Lett. 2012; 37:3798-3800.

Idoux E, Mertz J. Control of local intracellular calcium concentration with dynamic-clamp controlled 2-photon uncaging. PLoS One. 2011; 6(12):e28685. PMID: 22216105; PMCID: PMC3247215; DOI: 10.1371/journal.pone.0028685;

Mertz J. Optical sectioning microscopy with planar or structured illumination. Nat Methods. 2011 Sep 29; 8(10):811-9. PMID: 21959136; DOI: 10.1038/nmeth.1709;

Goldberg BB, Yurt A, Lu Y, Ramsay E, Koklu FH, Mertz J, Bifano TG, Ünlü MS. Chromatic and spherical aberration correction for silicon aplanatic solid immersion lens for fault isolation and photon emission microscopy of integrated circuits. Microelectronic Reliability. 2011; 51:1637-1639.

Lim D, Ford TN, Chu KK, Mertz J. Optically sectioned in vivo imaging with speckle illumination HiLo microscopy. J Biomed Opt. 2011 Jan-Feb; 16(1):016014. PMID: 21280920; PMCID: PMC3055591; DOI: 10.1117/1.3528656;

K Chu K, Lim D, Mertz J. Practical implementation of log-scale active illumination microscopy. Biomed Opt Express. 2010 Jul 16; 1(1):236-245. PMID: 21258461; PMCID: PMC3005158; DOI: 10.1364/BOE.1.000236;

Mertz J, Kim J. Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection. J Biomed Opt. 2010 Jan-Feb; 15(1):016027. PMID: 20210471; PMCID: PMC2917465; DOI: 10.1117/1.3324890;

Santos S, Chu KK, Lim D, Bozinovic N, Ford TN, Hourtoule C, Bartoo AC, Singh SK, Mertz J. Optically sectioned fluorescence endomicroscopy with hybrid-illumination imaging through a flexible fiber bundle. J Biomed Opt. 2009 May-Jun; 14(3):030502.View Related Profiles.

Mertz, Jerome
Singh, Satish

PMID: 19566286; DOI: 10.1117/1.3130266;

Mertz J. Introduction to Optical Microscopy. Roberts & Co. 2009.

Mertz J, Lim D, Chu KK, Bozinovic N, Ford T. Widefield fluorescence sectioning with HiLo microscopy. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:3229-30. PMID: 19964062; DOI: 10.1109/IEMBS.2009.5333166;

Lim D, Chu KK, Mertz J. Wide-field fluorescence sectioning with hybrid speckle and uniform-illumination microscopy. Opt Lett. 2008 Aug 15; 33(16):1819-21. PMID: 18709098; DOI: 10.1364/ol.33.001819;

Lim D, Chu KK, Mertz J. Autoconfocal microscopy with a cw laser and thermionic detection. Opt Lett. 2008 Jun 15; 33(12):1345-7. PMID: 18552953; DOI: 10.1364/ol.33.001345;

Bozinovic N, Ventalon C, Ford T, Mertz J. Fluorescence endomicroscopy with structured illumination. Opt Express. 2008 May 26; 16(11):8016-25. PMID: 18545511; DOI: 10.1364/oe.16.008016;

Lillis KP, Eng A, White JA, Mertz J. Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution. J Neurosci Methods. 2008 Jul 30; 172(2):178-84.View Related Profiles.

Mertz, Jerome
White, John

PMID: 18539336; PMCID: PMC2582024; DOI: 10.1016/j.jneumeth.2008.04.024;

Price GM, Chu KK, Truslow JG, Tang-Schomer MD, Golden AP, Mertz J, Tien J. Bonding of macromolecular hydrogels using perturbants. J Am Chem Soc. 2008 May 28; 130(21):6664-5.View Related Profiles.

Mertz, Jerome
Tien, Joe

PMID: 18454530; PMCID: PMC2394282; DOI: 10.1021/ja711340d;

Mertz J. B. Master and P. So (eds.) Handbook of biomedical nonlinear microscopy. Applications of second harmonic generation microscopy. Oxford University Press. 2008.

Leray A, Lillis K, Mertz J. Enhanced background rejection in thick tissue with differential-aberration two-photon microscopy. Biophys J. 2008 Feb 15; 94(4):1449-58. PMID: 17951295; PMCID: PMC2212671; DOI: 10.1529/biophysj.107.111476;

Chu KK, Lim D, Mertz J. Enhanced weak-signal sensitivity in two-photon microscopy by adaptive illumination. Opt Lett. 2007 Oct 01; 32(19):2846-8. PMID: 17909593; DOI: 10.1364/ol.32.002846;

Ventalon C, Heintzmann R, Mertz J. Dynamic speckle illumination microscopy with wavelet prefiltering. Opt Lett. 2007 Jun 01; 32(11):1417-9. PMID: 17546140; DOI: 10.1364/ol.32.001417;

Chu KK, Yi R, Mertz J. Graded-field autoconfocal microscopy. Opt Express. 2007 Mar 05; 15(5):2476-89. PMID: 19532485; DOI: 10.1364/oe.15.002476;

Leray A, Mertz J. Rejection of two-photon fluorescence background in thick tissue by differential aberration imaging. Opt Express. 2006 Oct 30; 14(22):10565-73. PMID: 19529458; DOI: 10.1364/oe.14.010565;

Ventalon C, Mertz J. Dynamic speckle illumination microscopy with translated versus randomized speckle patterns. Opt Express. 2006 Aug 07; 14(16):7198-209. PMID: 19529088; DOI: 10.1364/oe.14.007198;

Yi R, Chu KK, Mertz J. Graded-field microscopy with white light. Opt Express. 2006 Jun 12; 14(12):5191-200. PMID: 19516684; DOI: 10.1364/oe.14.005191;

Pons T, Mertz J. Membrane potential detection with second-harmonic generation and two-photon excited fluorescence: a theoretical comparison. Opt. Commun. 2006; 258:203-209.

Ventalon C, Mertz J. Quasi-confocal fluorescence sectioning with dynamic speckle illumination. Opt Lett. 2005 Dec 15; 30(24):3350-2. PMID: 16389828; DOI: 10.1364/ol.30.003350;

Katan C, Terenziani F, Mongin O, Werts MH, Porrès L, Pons T, Mertz J, Tretiak S, Blanchard-Desce M. Effects of (multi)branching of dipolar chromophores on photophysical properties and two-photon absorption. J Phys Chem A. 2005 Apr 07; 109(13):3024-37. PMID: 16833626; DOI: 10.1021/jp044193e;

Mertz J. Nonlinear microscopy: new techniques and applications. Curr Opin Neurobiol. 2004 Oct; 14(5):610-6. PMID: 15464895; DOI: 10.1016/j.conb.2004.08.013;

Porrès L, Mongin O, Katan C, Charlot M, Pons T, Mertz J, Blanchard-Desce M. Enhanced two-photon absorption with novel octupolar propeller-shaped fluorophores derived from triphenylamine. Org Lett. 2004 Jan 08; 6(1):47-50. PMID: 14703347; DOI: 10.1021/ol036041s;

Porrès L, Katan C, Mongin O, Pons T, Mertz J, Blanchard-Desce M. Two-Photon Absorption and Fluorescence in Nanoscale Multipolar Chromophores: Effect of dimensionality and charge-symmetry. J. Mol. Struct. 2004; 704:17-24.
Mertz J. R. Yuste and A. Konnerth (eds.) Imaging in Neuroscience and Development: A Laboratory Manual. A practical guide: building a two-photon laser-scanning microscope. Cold Spring Harbor Laboratory Press. New York. 2004.
Porrès L, Mongin O, Katan C, Charlot M, Batthula BKG, Jouikov V, Pons T, Mertz J, Blanchard-Desce M. Two-photon absorption and fluorescence with quadrupolar and branched chromophores – effect of structure and branching. J. Nonlinear Opt. Phys. & Mat. 2004; 13:451-459.
Pons T, Mertz J. Autoconfocal microscopy using nonlinear transmitted light detection. J. Opt. Soc. Am. B. 2004; 21:1486-1493.

Pons T, Moreaux L, Mongin O, Blanchard-Desce M, Mertz J. Mechanisms of membrane potential sensing with second-harmonic generation microscopy. J Biomed Opt. 2003 Jul; 8(3):428-31. PMID: 12880348; DOI: 10.1117/1.1581871;

Moreaux L, Pons T, Blanchard-Desce M, Mertz J. Electro-optic response of second-harmonic generation membrane potential sensors. Opt. Lett. 2003; 25:625-627.
Mongin O, Porres L, Katan C, Pons T, Mertz J, Blanchard-Desce M. Synthesis and two-photon absorption of highly soluble three-branched fluorenylene-vinylene derivatives. Tetrahed. Lett. 2003; 44:8121-8125.
Yang C, Mertz J. Transmission confocal laser scanning microscopy with a virtual pinhole based on nonlinear detection. Opt. Lett. 2003; 28:224-226.

Pons T, Moreaux L, Mertz J. Photoinduced flip-flop of amphiphilic molecules in lipid bilayer membranes. Phys Rev Lett. 2002 Dec 31; 89(28 Pt 1):288104. PMID: 12513184; DOI: 10.1103/PhysRevLett.89.288104;

Beaurepaire E, Mertz J. Epifluorescence collection in two-photon microscopy. Appl Opt. 2002 Sep 01; 41(25):5376-82. PMID: 12211567; DOI: 10.1364/ao.41.005376;

Mongin O, Porrès L, Moreaux L, Mertz J, Blanchard-Desce M. Synthesis and photophysical properties of new conjugated fluorophores designed for two-photon-excited fluorescence. Org Lett. 2002 Mar 07; 4(5):719-22. PMID: 11869110; DOI: 10.1021/ol017150e;

Ventelon L, Moreaux L, Mertz J, Blanchard-Desce M. Optimization of quadrupolar chromophores for molecular two-photon absorption. Synth. Metals. 2002; 127:17-21.
Mertz J, Moreaux L, Pons T. Perturbative theory of the electro-optic response of second-harmonic generation membrane potential sensors. Proc. SPIE. 2002; 4620:182-190.

Ventelon L, Charier S, Moreaux L, Mertz J, Blanchard-Desce M. Nanoscale Push-Push Dihydrophenanthrene Derivatives as Novel Fluorophores for Two-Photon-Excited Fluorescence. Angew Chem Int Ed Engl. 2001 Jun 01; 40(11):2098-2101. PMID: 29712227; DOI: 10.1002/1521-3773(20010601)40:11<2098::AID-ANIE2098>3.0.CO;2-0;

Ventelon L, Charier S, Moreaux L, Mertz J, Blanchard-Desce M. Nanoscale Push-Push Dihydrophenanthrene Derivatives as Novel Fluorophores for Two-Photon-Excited Fluorescence This work was supported by the Délégation Générale pour l'Armement (DGA), the Institut Curie, and the Centre National de la Recherche Scientifique (CNRS). L.V. and L.M. received fellowships from the DGA and CNRS, respectively. Angew Chem Int Ed Engl. 2001 Jun 01; 40(11):2098-2101. PMID: 11433455

Mertz J, Moreaux L, Beaurepaire E, Charpak S. P. Laporte and F. Salin (eds.) Systèmes Femtosecondes. Applications biologique de la microscopie nonlinéaire. University of St. Etienne Press. 2001.
Beaurepaire E, Moreaux L, Mertz J. P. Sebbah & J.-M. Tualle (eds.) Waves and Imaging through Complex Media. Simultaneous optical coherence and two-photon fluorescence microscopy. Kluwer Academic Publishers. 2001.
Ventelon L, Morel Y, Baldeck P, Moreaux L, Mertz J, Blanchard-Desce M. Novel quadrupolar extended biphenyl derivatives with enhanced nonlinear absorptivities for optical limiting applications. Nonlinear Optics. 2001; 27:249-258.
Charpak S, Mertz J, Beaurepaire E, Moreaux L, Delaney K. Odor evoked calcium signals in mitral cells. Proc. Natl. Acad. Sci. USA. 2001; 98:1230-1234.
Moreaux L, Sandre O, Charpak S, Blanchard-Desce M, Mertz J. Coherent Scattering in Multi-harmonic generation microscopy”. Biophys. J. 2001; 80:1568-1574.
Beaurepaire E, Oheim M, Mertz J. Ultra-deep two-photon fluorescence excitation in turbid media. Opt. Commun. 2001; 25-29(188).
Mertz J, Moreaux L,. Second harmonic generation by focused excitation of inhomogeneously distributed scatterers. Opt. Commun. 2001; 196:325-330.
Oheim M, Beaurepaire E, Chaigneau E, Mertz J, Charpak S. Two-photon microscopy in brain tissue: parameters influencing the imaging depth. J. Neuro. Meth. 2001; 112, 205:29-37.
Moreaux L, Sandre O, Blanchard-Desce M, Mertz J. Membrane imaging by simultaneous second-harmonic generation and two-photon microscopy. Opt. Lett. 2000; 25:320-322.
Moreaux L, Sandre O, Mertz J. Membrane imaging by second-harmonic generation microscopy. J. Opt. Soc. Am. B. 2000; 17:1685-1694.
Moreaux L, Sandre O, Blanchard-Desce M, Mertz J. Simultaneous second-harmonic generation and two-photon excited fluorescence microscopy. Nonlinear Optics. 2000; 25:183-188.
Mertz J. Radiative absorption, fluorescence and scattering of a classical dipole near a lossless interface: a unified description. J. Opt. Soc. Am. B. 2000; 17:1906-1917.
Beaurepaire E, Moreaux L, Amblard F, Mertz J. Combined scanning optical coherence and two-photon excitation microscopy. Opt. Lett. 1999; 24:969-971.
Ventelon L, Moreaux L, Mertz J, Blanchard-Desce M. New quadrupolar fluorophores with high two-photon excited fluorescence. Chem. Commun. 1999; 2055-2056.
Mertz J. Molecular photophysics involved in multi-photon excitation fluorescence microscopy. Eur. Phys. J. D. 1998; 3:53-66.
Courtois J-Y, Courty J-M, Mertz J. Internal Dynamics of Multi-Level Atoms Near a Vacuum-Dielectric Interface. Phys. Rev. A. 1996; 55:1862-1878.
Mertz J, Xu C, Webb WW. Single Molecule Detection by Two-Photon Excited Fluorescence. Opt. Lett. 1995; 20:2532-2534.
Paschotta R, Mertz J. Squeezed Light Generation by Twin Beam Control with an Optical Cavity. Phys. Rev. A. 1994; 49:2820-2826.
Mertz J, Hipp M, Mlynek J, Marti O. Optical Near-Field Imaging with a Semiconducting Probe Tip. Appl. Phys. Lett. 1994; 64:2338-2341.
Mertz J, Marti O, Mlynek J. Regulation of a Microcantilever Response by Force Feedback. Appl. Phys. Lett. 1993; 62:2344-2347.
Heidmann A, Mertz J. Mechanisms for Intensity Noise Reduction by Photon Control. J. Opt. Soc. Am. B. 1993; 10:1637-1642.
Mertz J, Heidmann A. Photon Noise Reduction by Controlled Deletion Techniques. J. Opt. Soc. Am. B. 1993; 10:745-752.
Rarity JG, Tapster PR, Levenson JA, Garreau JC, Abram I, Mertz J, Debuisshert T, Heidmann A, Fabre C, Giacobino E. Quantum Correlated Twin Beams. Appl. Phys. B. 1992; 55:250-255.
Mertz J, Debuisshert T, Heidmann A, Fabre C, Giacobino E. Improvements in the Observed Intensity Correlation of optical Parametric Oscillator Twin Beams. Opt. Lett. 1991; 1234-1236.
Mertz J, Heidmann A, Fabre C. Generation of Sub-Poissonian Light using Active Control with Twin Beams. Phys. Rev. A. 1991; 44:3229-3238.
Mertz J, Heidmann A, Fabre C, Giacobino E, Reynaud S. Observation of High Intensity Sub-Poissonian Light using an Optical Parametric Oscillator. Phys. Rev. Lett. 1990; 64:2897-2900.
Amir, Hu RJ, Keilman F, Mertz J, Elias L. Injection Locking Experiment at the UCSB FEL. Nucl. Inst. and Meth. A. 1988; 272:174-179.
Slusher RE, Yurke B, Mertz J. Experimental Progress in Intracavity Generation of Squeezed light using Resonant Atomic Nonlinearities. J. Mod. Opt. 1987; 34(6/7):761-769.
Slusher RE, Hollberg L, Yurke B, Mertz J, Valley J. Observation of Squeezed States Generated by Four-Wave Mixing in an Optical Cavity. Phys. Rev. Lett. 1985; 55:2409-2412.
Slusher RE, Hollberg L, Yurke B, Mertz J, Valley J. Squeezed States in Optical Cavities: A Spontaneous Emission Noise Limit. Phys. Rev. A. 1985; 31:3512-3515.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 142 publications over 38 distinct years, with a maximum of 10 publications in 2001 and 2023

Bar chart showing 142 publications over 38 distinct years, with a maximum of 10 publications in 2001 and 2023

Year	Publications
1985	2
1987	1
1988	1
1990	1
1991	2
1992	1
1993	3
1994	2
1995	1
1996	1
1998	1
1999	2
2000	4
2001	10
2002	5
2003	4
2004	6
2005	2
2006	4
2007	4
2008	6
2009	3
2010	2
2011	4
2012	7
2013	6
2014	8
2015	6
2016	2
2017	3
2018	7
2019	3
2020	4
2021	8
2022	3
2023	10
2024	2
2025	1