Jerome Mertz, PhD
Professor
Boston University College of Engineering
Biomedical Engineering

PhD, University of California, Santa Barbara
BA, Princeton University



Jerome Mertz, PhD, is professor of Biomedical Engineering and director of the Biomicroscopy Laboratory at Boston University. Prior to joining Boston University, he was a CNRS researcher at the École Supérieure de Physique et de Chimie Industrielles in Paris. He specializes in the development of novel microscopy techniques for biological imaging

Professor Mertz’s lab focuses on the development and applications of novel optical microscopy techniques for biomedical imaging. Some specific topics include imaging through complex media, imaging through a single optical fiber, and oblique back-illumination microscopy.


Ultrafast high-contrast voltage imaging in freely moving animals
03/15/2022 - 02/28/2025 (PI)
NIH/National Institute of Neurological Disorders & Stroke
1R34NS127098-01

Multi-layer neuronal imaging with reverberation multiphoton microscopy
03/15/2020 - 12/31/2024 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS116139-05

Fast, large-scale neuronal imaging with multi-z confocal microscopy
02/01/2020 - 11/30/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB029171-04

Speckle-free phase-contrast ultrasound imaging
09/15/2019 - 08/31/2022 (PI)
NIH/National Institute of General Medical Sciences
5R21GM134216-02

Retinal/choroidal imaging with transcranial back-illumination
09/01/2018 - 08/31/2021 (PI)
NIH/National Eye Institute
5R21EY029486-02

Development of label-free computational flow cytometry for high-throughput micro-organism classification
06/01/2018 - 03/31/2021 (PI)
NIH/National Institute of General Medical Sciences
5R21GM128020-02

High dynamic range multiphoton microscopy for large-scale imaging
09/30/2016 - 07/31/2020 (Multi-PI)
PI: Jerome Mertz, PhD
NIH/National Eye Institute
5R21EY027549-02

UNS: Fluorescence light-field imaging with a lensless flexible fiber bundle
06/01/2015 - 11/30/2019 (PI)
National Science Foundation
CBET-1508988

High Resolution Phase Contrast Endoscopy
12/15/2013 - 11/30/2019 (PI)
NIH/National Cancer Institute
5R01CA182939-04

Advanced laser scanning confocal microscope for multiple users
08/01/2018 - 07/31/2019 (PI)
NIH/Office of the Director
1S10OD024993-01

Showing 10 of 26 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Multi-Layer Neuronal Imaging with Reverberation Multiphoton Microscopy 5R01NS116139-05
2023 Multi-layer neuronal imaging with reverberation multiphoton microscopy 5R01NS116139-04
2023 Fast, large-scale neuronal imaging with multi-z confocal microscopy 5R01EB029171-04
2022 Ultrafast high-contrast voltage imaging in freely moving animals 1R34NS127098-01
2022 Multi-layer neuronal imaging with reverberation multiphoton microscopy 5R01NS116139-03
2022 Fast, large-scale neuronal imaging with multi-z confocal microscopy 5R01EB029171-03
2021 Multi-layer neuronal imaging with reverberation multiphoton microscopy 5R01NS116139-02
2021 Fast, large-scale neuronal imaging with multi-z confocal microscopy 5R01EB029171-02
2020 Multi-layer neuronal imaging with reverberation multiphoton microscopy 1R01NS116139-01
2020 Fast, large-scale neuronal imaging with multi-z confocal microscopy 1R01EB029171-01
Showing 10 of 42 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Zheng S, Koyama M, Mertz J. Multiplane HiLo microscopy with speckle illumination and non-local means denoising. J Biomed Opt. 2023 Nov; 28(11):116502. PMID: 38078150; DOI: 10.1117/1.JBO.28.11.116502;
     
  2. Zhao B, Mertz J. Resolution enhancement with deblurring by pixel reassignment (DPR). bioRxiv. 2023 Sep 16. PMID: 37546886; DOI: 10.1101/2023.07.24.550382;
     
  3. Mahler S, Huang YX, Liang M, Avalos A, Tyszka JM, Mertz J, Yang C. Assessing depth sensitivity in laser interferometry speckle visibility spectroscopy (iSVS) through source-to-detector distance variation and cerebral blood flow monitoring in humans and rabbits. Biomed Opt Express. 2023 Sep 01; 14(9):4964-4978. PMID: 37791277; DOI: 10.1364/BOE.498815;
     
  4. Weber TD, Moya MV, Kiliç K, Mertz J, Economo MN. High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations. Nat Neurosci. 2023 Sep; 26(9):1642-1650.View Related Profiles. PMID: 37604887
     
  5. Lowet E, Sheehan DJ, Chialva U, De Oliveira Pena R, Mount RA, Xiao S, Zhou SL, Tseng HA, Gritton H, Shroff S, Kondabolu K, Cheung C, Wang Y, Piatkevich KD, Boyden ES, Mertz J, Hasselmo ME, Rotstein HG, Han X. Theta and gamma rhythmic coding through two spike output modes in the hippocampus during spatial navigation. Cell Rep. 2023 Aug 29; 42(8):112906.View Related Profiles. PMID: 37540599; DOI: 10.1016/j.celrep.2023.112906;
     
  6. Xiao S, Cunningham WJ, Kondabolu K, Lowet E, Moya MV, Mount R, Ravasio C, Economo MN, Han X, Mertz J. Large-scale deep tissue voltage imaging with targeted illumination confocal microscopy. bioRxiv. 2023 Jul 21.View Related Profiles. PMID: 37502929; DOI: 10.1101/2023.07.21.548930;
     
  7. Zhao B, Koyama M, Mertz J. High-resolution multi-z confocal microscopy with a diffractive optical element. Biomed Opt Express. 2023 Jun 01; 14(6):3057-3071. PMID: 37342696; DOI: 10.1364/BOE.491538;
     
  8. Abdelfattah AS, Zheng J, Singh A, Huang YC, Reep D, Tsegaye G, Tsang A, Arthur BJ, Rehorova M, Olson CVL, Shuai Y, Zhang L, Fu TM, Milkie DE, Moya MV, Weber TD, Lemire AL, Baker CA, Falco N, Zheng Q, Grimm JB, Yip MC, Walpita D, Chase M, Campagnola L, Murphy GJ, Wong AM, Forest CR, Mertz J, Economo MN, Turner GC, Koyama M, Lin BJ, Betzig E, Novak O, Lavis LD, Svoboda K, Korff W, Chen TW, Schreiter ER, Hasseman JP, Kolb I. Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator. Neuron. 2023 May 17; 111(10):1547-1563.e9.View Related Profiles. PMID: 37015225; DOI: 10.1016/j.neuron.2023.03.009;
     
  9. Zheng S, Mertz J. Correcting sampling bias in speckle contrast imaging. Opt Lett. 2022 Dec 15; 47(24):6333-6336. PMID: 36538431; DOI: 10.1364/OL.474604;
     
  10. Zheng S, Mertz J. Direct characterization of tissue dynamics with laser speckle contrast imaging. Biomed Opt Express. 2022 Aug 01; 13(8):4118-4133. PMID: 36032565; DOI: 10.1364/BOE.462913;
     
Showing 10 of 137 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 137 publications over 36 distinct years, with a maximum of 10 publications in 2001

YearPublications
19852
19871
19881
19901
19912
19921
19933
19942
19951
19961
19981
19992
20004
200110
20025
20034
20046
20052
20064
20074
20086
20093
20102
20114
20127
20136
20148
20156
20162
20173
20187
20193
20204
20218
20223
20238

2020 Boston University: Innovator of the Year
2014 American Institute for Medical and Biological Engineering: Fellow
2013 Optical Society of America: Fellow
2012 Focus on Microscopy, Singapore: Plenary Speaker
2009 Optical Society of America: Travelling Lecturer
2009 Royal Microscopical Society: Lecturer
2009 ECBO, Munich, Germany: Plenary Speaker
2001 French Physical Society: Aimé Cotton Prize
2000 French Optical Society: Fabry-de-Gramont Prize
1992-1994 Alexander-von-Humboldt fellowship
Contact for Mentoring:

24 Cummington St
Boston MA 02215
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