Jayandra J. Himali, PhD
Adjunct Associate Professor
Boston University Chobanian & Avedisian School of Medicine

PhD, Boston University School of Public Health
MSc, Tribhuvan University
BSc, Tribhuvan University

Jayandra Jung Himali, PhD, serves as an adjunct Associate Professor of Neurology and Biostatistics at Boston University Schools of Medicine and of Public Health, and a Center Faculty Member of the Framingham Heart Study (FHS). He has been engaged in collaborative public health research and teaching for over a decade. As a senior Biostatistician at the Neurology core of FHS, his research efforts are focused on the interrelated areas of: (1) the epidemiology of dementia and Alzheimer’s disease (AD) and relating traditional and novel biomarkers to the risk of dementia and AD; (2) the epidemiology of stroke and vascular cognitive impairment; (3) understanding vascular contributions to cognitive impairment and dementia including AD; and (4) investigating the role of modifiable lifestyle factors: sleep, diet and physical activity on the incidence of dementia, cognitive decline and MRI-defined brain aging. His research is also focused on outcome assessment in Epilepsy, Parkinson’s disease, and neuropathology. He has received the Nepal Bidhya Bhusan Class ‘A’ Medal from the government of Nepal for highest academic achievement in doctoral studies.

Framingham Heart Study

Identification of a missing key element underlying apoE2 neuroprotection in Alzheimers disease and the aging brain
09/30/2018 - 09/30/2019 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. DeCarli C, Maillard P, Pase MP, Beiser AS, Kojis D, Satizabal CL, Himali JJ, Aparicio HJ, Fletcher E, Seshadri S. Trends in Intracranial and Cerebral Volumes of Framingham Heart Study Participants Born 1930 to 1970. JAMA Neurol. 2024 May 01; 81(5):471-480.View Related Profiles. PMID: 38526486; PMCID: PMC10964161; DOI: 10.1001/jamaneurol.2024.0469;
  2. Martirosian RA, Wiedner CD, Sanchez J, Mun KT, Marla K, Teran C, Thirion M, Liebeskind DS, McGrath ER, Zucker JM, Bernal R, Beiser AS, DeCarli C, Himali JJ, Seshadri S, Hinman JD. Association of Incident Stroke Risk With an IL-18-Centered Inflammatory Network Biomarker Composite. Stroke. 2024 Jun; 55(6):1601-1608.View Related Profiles. PMID: 38690658; DOI: 10.1161/STROKEAHA.123.044719;
  3. Krefman AE, Stephen J, Carolan P, Sedaghat S, Mansolf M, Soumare A, Gross AL, Aiello AE, Singh-Manoux A, Ikram MA, Helmer C, Tzourio C, Satizabal C, Levine DA, Lloyd-Jones D, Briceño EM, Sorond FA, Wolters FJ, Himali J, Launer LJ, Zhao L, Haan M, Lopez OL, Debette S, Seshadri S, Judd SE, Hughes TM, Gudnason V, Scholtens D, Allen NB. Cohort Profile: Dementia Risk Prediction Project (DRPP). Int J Epidemiol. 2024 Feb 01; 53(1).View Related Profiles. PMID: 38339864; PMCID: PMC10858348; DOI: 10.1093/ije/dyae012;
  4. Pase MP, Himali JJ, Puerta R, Beiser AS, Gonzales MM, Satizabal CL, Yang Q, Aparicio HJ, Kojis DJ, Decarli CS, Lopez OL, Longstreth W, Gudnason V, Mosley TH, Bis JC, Fohner A, Psaty BM, Boada M, García-González P, Valero S, Marquié M, Tracy R, Launer LJ, Ruiz A, Fornage M, Seshadri S. Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024 Feb 27; 102(4):e208075.View Related Profiles. PMID: 38290090
  5. Zhao A, Balcer LJ, Himali JJ, O'Donnell A, Rahimpour Y, DeCarli C, Gonzales MM, Aparicio HJ, Ramos-Cejudo J, Kenney R, Beiser A, Seshadri S, Salinas J. Association of Loneliness with Functional Connectivity MRI, Amyloid-ß PET, and Tau PET Neuroimaging Markers of Vulnerability for Alzheimer's Disease. J Alzheimers Dis. 2024; 99(4):1473-1484.View Related Profiles. PMID: 38820017; DOI: 10.3233/JAD-231425;
  6. Baril AA, Kojis DJ, Himali JJ, Decarli CS, Sanchez E, Johnson KA, El Fakhri G, Thibault E, Yiallourou SR, Himali D, Cavuoto MG, Pase MP, Beiser AS, Seshadri S. Association of Sleep Duration and Change Over Time With Imaging Biomarkers of Cerebrovascular, Amyloid, Tau, and Neurodegenerative Pathology. Neurology. 2024 Jan 09; 102(1):e207807.View Related Profiles. PMID: 38165370; PMCID: PMC10834132; DOI: 10.1212/WNL.0000000000207807;
  7. Himali JJ, Baril AA, Cavuoto MG, Yiallourou S, Wiedner CD, Himali D, DeCarli C, Redline S, Beiser AS, Seshadri S, Pase MP. Association Between Slow-Wave Sleep Loss and Incident Dementia. JAMA Neurol. 2023 Dec 01; 80(12):1326-1333.View Related Profiles. PMID: 37902739; PMCID: PMC10616771; DOI: 10.1001/jamaneurol.2023.3889;
  8. Melo van Lent D, Mesa HG, Short MI, Gonzales MM, Aparicio HJ, Salinas J, Yuan C, Jacques PF, Beiser A, Seshadri S, Jacob ME, Himali JJ. Association between dietary inflammatory index score and incident dementia: results from the Framingham heart Study offspring cohort. medRxiv. 2023 Aug 22.View Related Profiles. PMID: 37662354; PMCID: PMC10473791; DOI: 10.1101/2023.08.21.23294374;
  9. Fongang B, Satizabal C, Kautz TF, Wadop YN, Muhammad JAS, Vasquez E, Mathews J, Gireud-Goss M, Saklad AR, Himali J, Beiser A, Cavazos JE, Mahaney MC, Maestre G, DeCarli C, Shipp EL, Vasan RS, Seshadri S. Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study. Sci Rep. 2023 Aug 21; 13(1):13622.View Related Profiles. PMID: 37604954; PMCID: PMC10442369; DOI: 10.1038/s41598-023-40872-5;
  10. Pase MP, Harrison S, Misialek JR, Kline CE, Cavuoto M, Baril AA, Yiallourou S, Bisson A, Himali D, Leng Y, Yang Q, Seshadri S, Beiser A, Gottesman RF, Redline S, Lopez O, Lutsey PL, Yaffe K, Stone KL, Purcell SM, Himali JJ. Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults. JAMA Netw Open. 2023 Jul 03; 6(7):e2325152.View Related Profiles. PMID: 37462968; PMCID: PMC10354680; DOI: 10.1001/jamanetworkopen.2023.25152;
Showing 10 of 129 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 129 publications over 17 distinct years, with a maximum of 19 publications in 2017 and 2019


2014 Government of Nepal: Nepal Bidhya Bhusan Class ‘A’ Medal
Contact for Mentoring:

72 E. Concord St Robinson (B)
Boston MA 02118
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