Jason Lon Chang, Sc.B.
MD Student
Boston University Chobanian & Avedisian School of Medicine




I am interested in lung development and pulmonary vascular biology. My previous research examines the role of developmental processes in pulmonary vascular disease including bronchopulmonary dysplasia and pulmonary arterial hypertension (PAH). I am particularly interested in metabolic and neo-arteriogenic processes that drive vascular transformation in PAH.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Li X, Hegarty K, Lin F, Chang JL, Abdalla A, Dhanabalan K, Solomevich SO, Song W, Roder K, Yao C, Lu W, Carmeliet P, Choudhary G, Dennery PA, Yao H. Endothelial Cpt1a Inhibits Neonatal Hyperoxia-Induced Pulmonary Vascular Remodeling by Repressing Endothelial-Mesenchymal Transition. Adv Sci (Weinh). 2025 Jan 12; e2415824. PMID: 39799584; DOI: 10.1002/advs.202415824;
     
  2. Sanges S, Tian W, Dubucquoi S, Chang JL, Collet A, Launay D, Nicolls MR. B-cells in pulmonary arterial hypertension: friend, foe or bystander? Eur Respir J. 2024 Apr; 63(4). PMID: 38485150; PMCID: PMC11043614; DOI: 10.1183/13993003.01949-2023;
     
  3. Zhao L, Cunningham CM, Andruska AM, Schimmel K, Ali MK, Kim D, Gu S, Chang JL, Spiekerkoetter E, Nicolls MR. Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs. Lab Anim (NY). 2024 Feb; 53(2):43-55. PMID: 38297075; PMCID: PMC10834367; DOI: 10.1038/s41684-023-01322-x;
     
  4. Kim D, Tian W, Wu TT, Xiang M, Vinh R, Chang JL, Gu S, Lee S, Zhu Y, Guan T, Schneider EC, Bao E, Dixon JB, Kao P, Pan J, Rockson SG, Jiang X, Nicolls MR. Abnormal Lymphatic Sphingosine-1-Phosphate Signaling Aggravates Lymphatic Dysfunction and Tissue Inflammation. Circulation. 2023 Oct 17; 148(16):1231-1249. PMID: 37609838; PMCID: PMC10592179; DOI: 10.1161/CIRCULATIONAHA.123.064181;
     
  5. Kim D, Tian W, Wu TT, Xiang M, Vinh R, Chang J, Gu S, Lee S, Zhu Y, Guan T, Schneider EC, Bao E, Dixon JB, Kao P, Pan J, Rockson SG, Jiang X, Nicolls MR. Abnormal lymphatic S1P signaling aggravates lymphatic dysfunction and tissue inflammation. medRxiv. 2023 Jun 12. PMID: 37398237; PMCID: PMC10312855; DOI: 10.1101/2023.06.08.23291175;
     
  6. Zhao L, Cunningham CM, Andruska AM, Schimmel K, Ali MK, Kim D, Gu S, Chang JL, Spiekerkoetter E, Nicolls MR. Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs. bioRxiv. 2023 May 20. PMID: 37293045; PMCID: PMC10245737; DOI: 10.1101/2023.05.19.541527;
     
  7. Yao H, Wallace J, Peterson AL, Scaffa A, Rizal S, Hegarty K, Maeda H, Chang JL, Oulhen N, Kreiling JA, Huntington KE, De Paepe ME, Barbosa G, Dennery PA. Timing and cell specificity of senescence drives postnatal lung development and injury. Nat Commun. 2023 Jan 17; 14(1):273. PMID: 36650158; PMCID: PMC9845377; DOI: 10.1038/s41467-023-35985-4;
     
  8. Chang JL, Gong J, Rizal S, Peterson AL, Chang J, Yao C, Dennery PA, Yao H. Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury. Respir Res. 2022 Aug 13; 23(1):205. PMID: 35964084; PMCID: PMC9375342; DOI: 10.1186/s12931-022-02135-1;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 4 distinct years, with a maximum of 4 publications in 2023

YearPublications
20221
20234
20242
20251

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