Huiping Zhang, PhD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Psychiatry

PhD, Queen's University
MS, Tongji Medical University
BS, Central China Normal University



Huiping Zhang, PhD, is an Associate Professor of Psychiatry at the Chobanian and Avedisian School of Medicine. He has a long history with the Yale University School of Medicine, where he completed his postdoc training and then served as a Research Associate Scientist (equivalent to Research Assistant Professor), Assistant Professor (tenure-track), and Research Scientist (equivalent to Research Associate Professor) before coming to Boston University. He is an editorial board member of academic journals such as the Journal of Addiction Research & Therapy, the Journal of Depression & Anxiety, and PLOS One. His research focused on genetic and epigenetic studies of substance use disorders (SUDs) and related psychiatric disorders and traits. He is currently the PI of two research grants (R01 and R21) from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and one research grant from the Boston University Clinical Translational Science Institute (CTSI). Additionally, he is the subcontract PI of a R01 from the National Institute of Child Health and Human Development (NICHD).

Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Biomedical Genetics

Member
Boston University
Genome Science Institute


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Identifying Brain Epitranscriptomic Changes Associated with Alcohol Use Disorder
03/01/2022 - 12/31/2026 (PI)
NIH/National Institute on Alcohol Abuse and Alcoholism
5R01AA029758-03

Association of maternal, fetal, and placental biomarkers with neonatal neuroimaging and development following in-utero opioid exposure
09/01/2023 - 08/31/2026 (Subcontract PI)
Boston Medical Center Corporation NIH NICHD
1R01HD113143-01

Safety, pharmacokinetics and efficacy of extended-release naltrexone in pregnant women with opioid use disorder
10/01/2018 - 05/31/2023 (Subcontract PI)
Boston Medical Center Corporation NIH NICHD
5R01HD096798-05

Brain microRNA-mRNA regulatory networks and alcohol use disorders
08/01/2017 - 07/31/2022 (PI)
NIH/National Institute on Alcohol Abuse and Alcoholism
5R01AA025080-05

Salivary MicroRNAs as Biomarkers for Alcohol Dependence
08/01/2017 - 04/30/2019 (PI)
NIH/National Institute on Alcohol Abuse and Alcoholism
7R21AA023068-03


Association of maternal, fetal and placental biomarkers with neonatal neuroimaging and development following in-utero opioid exposure
09/01/2023 - 08/31/2026 (Subcontract PI)
Boston Medical Center - NIH/National Institute of Child Health and Human Development
1R01HD113143-01

Effects of prenatal opioid exposure on placental DNA methylation and gene expression
03/01/2022 - 02/28/2024 (Subcontract PI)
Boston Medical Center - March of Dimes


Title

Adverse childhood experiences and alcohol misuse in Latino adolescents: Testing biopsychosocial and cultural mechanisms
02/01/2022 - 01/01/2027 (Co-Mentor)
Massachusetts General Hospital - NIH/National Institute on Alcohol Abuse and Alcoholism
K08AA029150-03

Single-Nucleus RNA Sequencing Analysis of Transcriptome Changes in the Postmortem Ventral Tegmental Area of Individuals with Alcohol Use Disorder
06/15/2024 - 06/14/2025 (PI)
Boston University Genome Science Institute

Functional validation of 22q11.2 deletion syndrome-associated missense mutation in MRPL40 using CRISPR-Cas9 gene editing
01/01/2022 - 12/31/2022 (PI)
Wing Tat Lee Research Award

Transmission Electron Microscope
06/15/2020 - 06/14/2021 (Co-Investigator)
NIH NIH
1S10OD028571-01

Epigenetic study of cocaine use disorder using a rat model
07/01/2018 - 08/31/2019 (PI)
Boston University CTSI Pilot Award


Yr Title Project-Sub Proj Pubs
2024 Identifying Brain Epitranscriptomic Changes Associated with Alcohol Use Disorder 5R01AA029758-03
2023 Identifying Brain Epitranscriptomic Changes Associated with Alcohol Use Disorder 5R01AA029758-02
2022 Identifying Brain Epitranscriptomic Changes Associated with Alcohol Use Disorder 1R01AA029758-01
2020 Brain microRNA-mRNA regulatory networks and alcohol use disorders 5R01AA025080-05 13
2019 Brain microRNA-mRNA regulatory networks and alcohol use disorders 5R01AA025080-04 13
2018 Brain microRNA-mRNA regulatory networks and alcohol use disorders 5R01AA025080-03 13
2017 Brain microRNA-mRNA regulatory networks and alcohol use disorders 7R01AA025080-02 13
2016 Brain microRNA-mRNA regulatory networks and alcohol use disorders 1R01AA025080-01 13
2016 Salivary MicroRNAs as Biomarkers for Alcohol Dependence 5R21AA023068-02 8
2016 Salivary MicroRNAs as Biomarkers for Alcohol Dependence 7R21AA023068-03 8
Showing 10 of 17 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Cai Y, Zhu ZH, Qi Q, Yin XY, Jia NN, Hou WL, Chen P, Man LJ, Wang PJ, Qian S, Wang WX, Zhang TH, Wang JJ, Zhang H, Hui L. The negative association of serum complement 3 and 4 levels with visuospatial/constructional function in first-episode patients with schizophrenia. Schizophr Res. 2024 Feb; 264:404-406. PMID: 38237363; DOI: 10.1016/j.schres.2024.01.017;
     
  2. Liu Y, Koo JS, Zhang H. Chronic intermittent ethanol exposure-induced m6A modifications around mRNA stop codons of opioid receptor genes. Epigenetics. 2024 Dec; 19(1):2294515. PMID: 38118075; PMCID: PMC10761033; DOI: 10.1080/15592294.2023.2294515;
     
  3. Borrelli KN, Wingfield KK, Yao EJ, Zamorano CA, Sena KD, Beierle JA, Roos MA, Zhang H, Wachman EM, Bryant CD. Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. Neuropharmacology. 2023 Dec 01; 240:109732.View Related Profiles. PMID: 37774943; PMCID: PMC10598517; DOI: 10.1016/j.neuropharm.2023.109732;
     
  4. Kumaresan V, Lim Y, Juneja P, Tipton AE, de Guglielmo G, Carrette LLG, Kallupi M, Maturin L, Liu Y, George O, Zhang H. Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway. Biomedicines. 2023 May 05; 11(5).View Related Profiles. PMID: 37239038; PMCID: PMC10216163; DOI: 10.3390/biomedicines11051368;
     
  5. Cai Y, Zhu ZH, Li RH, Yin XY, Chen RF, Man LJ, Hou WL, Zhu HL, Wang J, Zhang H, Jia QF, Hui L. Association between increased serum interleukin-8 levels and improved cognition in major depressive patients with SSRIs. BMC Psychiatry. 2023 Feb 23; 23(1):122. PMID: 36823619; PMCID: PMC9948487; DOI: 10.1186/s12888-023-04616-z;
     
  6. Chen RF, Cai Y, Zhu ZH, Hou WL, Chen P, Wang J, Jia YM, Zhu ZB, Zhang YH, Tao LY, Wu JW, Zhang J, Zhang H, Wang ZX, Jia QF, Hui L. Sleep disorder as a clinical risk factor of major depression: associated with cognitive impairment. Asian J Psychiatr. 2022 Oct; 76:103228. PMID: 35973338; DOI: 10.1016/j.ajp.2022.103228;
     
  7. Liu Y, Zhang H. RNA m6A Modification Changes in Postmortem Nucleus Accumbens of Subjects with Alcohol Use Disorder: A Pilot Study. Genes (Basel). 2022 May 27; 13(6). PMID: 35741720; PMCID: PMC9222907; DOI: 10.3390/genes13060958;
     
  8. Borrelli KN, Wachman EM, Beierle JA, Taglauer ES, Jain M, Bryant CD, Zhang H. Effect of Prenatal Opioid Exposure on the Human Placental Methylome. Biomedicines. 2022 May 17; 10(5).View Related Profiles. PMID: 35625888; PMCID: PMC9138340; DOI: 10.3390/biomedicines10051150;
     
  9. Lim Y, Beane-Ebel JE, Tanaka Y, Ning B, Husted CR, Henderson DC, Xiang Y, Park IH, Farrer LA, Zhang H. Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks. Transl Psychiatry. 2021 10 02; 11(1):504.View Related Profiles. PMID: 34601489; PMCID: PMC8487426; DOI: 10.1038/s41398-021-01635-w;
     
  10. Moazzam M, Yim T, Kumaresan V, Henderson DC, Farrer LA, Zhang H. Analysis of telomere length variation and Shelterin complex subunit gene expression changes in ethanol-exposed human embryonic stem cells. J Psychiatr Res. 2021 11; 143:543-549.View Related Profiles. PMID: 33243459; PMCID: PMC8126580; DOI: 10.1016/j.jpsychires.2020.11.027;
     
Showing 10 of 80 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 80 publications over 22 distinct years, with a maximum of 9 publications in 2015

YearPublications
19961
20021
20041
20062
20074
20082
20093
20104
20112
20128
20135
20144
20159
20167
20177
20182
20194
20205
20211
20223
20234
20241

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Substance Use Disorders
Psychiatric Genetics
Epigenetics
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