Honghuang Lin, PhD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, National University of Singapore (NUS)




My research focuses on the development of computational tools to study molecular mechanisms underlying cardiovascular disease and Alzheimer’s disease using multi-omics data. We are also building machine learning models for the early diagnosis of diseases using a large collection of blood biomarkers, images, digital data and electronic health records. The ultimate objective is to develop new computational strategies for the disease prevention and intervention.

Member
Boston University
BU-BMC Cancer Center


Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Integrated Digital Technology Platform for Optimization of Precision Brain Health
07/01/2020 - 06/30/2024 (Co-PI)
PI: Rhoda Au, PhD
American Heart Association


Identification of digital biomarkers for Alzheimer's disease
03/01/2020 - 02/28/2023 (PI)
Alzheimer's Association


Digital, risk-based screening for Atrial Fibrillation in the European Community: AFFECT-EU
01/01/2020 - 12/31/2022 (PI)
European Commission




Title

Biostatistical analysis of TOPMed genetics data
06/01/2019 - 05/31/2020 (PI)
University of Connecticut Health Center


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Kornej J, Hanger VA, Trinquart L, Ko D, Preis SR, Benjamin EJ, Lin H. New biomarkers from multiomics approaches - improving risk prediction of atrial fibrillation. Cardiovasc Res. 2021 Mar 05.View Related Profiles. PMID: 33751041; DOI: 10.1093/cvr/cvab073;
     
  2. Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles. PMID: 33470944; DOI: 10.2196/24773;
     
  3. Lin H, Karjadi C, Ang TFA, Prajakta J, McManus C, Alhanai TW, Glass J, Au R. Identification of digital voice biomarkers for cognitive health. Explor Med. 2020; 1:406-417.View Related Profiles. PMID: 33665648; DOI: 10.37349/emed.2020.00028;
     
  4. Corlin L, Liu C, Lin H, Leone D, Yang Q, Ngo D, Levy D, Cupples LA, Gerszten RE, Larson MG, Vasan RS. Proteomic Signatures of Lifestyle Risk Factors for Cardiovascular Disease: A Cross-Sectional Analysis of the Plasma Proteome in the Framingham Heart Study. J Am Heart Assoc. 2021 Jan 05; 10(1):e018020.View Related Profiles. PMID: 33372532; DOI: 10.1161/JAHA.120.018020;
     
  5. Hall AW, Chaffin M, Roselli C, Lin H, Lubitz SA, Bianchi V, Geeven G, Bedi K, Margulies KB, de Laat W, Tucker NR, Ellinor PT. Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation. Circ Genom Precis Med. 2020 12; 13(6):e003085. PMID: 33155827
     
  6. Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE, Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT, Fornage M, Paus T, Debette S, Arfan Ikram M, Schmidt H, Schmidt R, Seshadri S. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nat Commun. 2020 09 22; 11(1):4796.View Related Profiles. PMID: 32963231; DOI: 10.1038/s41467-020-18367-y;
     
  7. Miao X, Liu W, Fan B, Lin H. Transcriptomic Heterogeneity of Alzheimer's Disease Associated with Lipid Genetic Risk. Neuromolecular Med. 2020 12; 22(4):534-541. PMID: 32862331; DOI: 10.1007/s12017-020-08610-6;
     
  8. Lin H, Sardana M, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano NL, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Cardiovascular Disease Risk. Circ Res. 2020 Oct 23; 127(10):1253-1260.View Related Profiles. PMID: 32842915; DOI: 10.1161/CIRCRESAHA.120.317578;
     
  9. Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H, Teumer A, Li-Gao R, Yao J, Guo X, Brody JA, Müller-Nurasyid M, Schramm K, Verweij N, van den Berg ME, van Setten J, Isaacs A, Ramírez J, Warren HR, Padmanabhan S, Kors JA, de Boer RA, van der Meer P, Sinner MF, Waldenberger M, Psaty BM, Taylor KD, Völker U, Kanters JK, Li M, Alonso A, Perez MV, Vaartjes I, Bots ML, Huang PL, Heckbert SR, Lin HJ, Kornej J, Munroe PB, van Duijn CM, Asselbergs FW, Stricker BH, van der Harst P, Kääb S, Peters A, Sotoodehnia N, Rotter JI, Mook-Kanamori DO, Dörr M, Felix SB, Linneberg A, Hansen T, Arking DE, Kooperberg C, Benjamin EJ, Lunetta KL, Ellinor PT, Lubitz SA. Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation. Circ Genom Precis Med. 2020 10; 13(5):387-395.View Related Profiles. PMID: 32822252
     
  10. Vaze A, Tran KV, Tanriverdi K, Sardana M, Lessard D, Donahue JK, Barton B, Aurigemma G, Lubitz SA, Lin H, Nasr GH, Mandapati A, Benjamin EJ, Vasan RS, Freedman JE, McManus DD. Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study. PLoS One. 2020; 15(8):e0236960.View Related Profiles. PMID: 32813736; DOI: 10.1371/journal.pone.0236960;
     
Showing 10 of 148 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 148 publications over 17 distinct years, with a maximum of 21 publications in 2018

YearPublications
20041
20052
20069
20078
20084
20092
20114
20125
20134
201417
20155
201615
201717
201821
201913
202019
20212
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bioinformatics
Machine learning
Microarray data analysis
Next generation sequencing
Multi-omics data integration

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

75 E. Newton St Old Evans Building
Boston MA 02118
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