Honghuang Lin, PhD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Computational Biomedicine

PhD, National University of Singapore (NUS)




My research focuses on the development of computational tools to study molecular mechanisms underlying cardiovascular disease and Alzheimer’s disease using multi-omics data. We are also building machine learning models for the early diagnosis of diseases using a large collection of blood biomarkers, images, digital data and electronic health records. The ultimate objective is to develop new computational strategies for the disease prevention and intervention.

Member
Boston University
BU-BMC Cancer Center


Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Integrated Digital Technology Platform for Optimization of Precision Brain Health
07/01/2020 - 06/30/2024 (Multi-PI)
PI: Honghuang Lin, PhD
American Heart Association


Identification of digital biomarkers for Alzheimer's disease
03/01/2020 - 02/28/2023 (PI)
Alzheimer's Association


Digital, risk-based screening for Atrial Fibrillation in the European Community: AFFECT-EU
01/01/2020 - 12/31/2022 (PI)
European Commission




Title

Biostatistical analysis of TOPMed genetics data
06/01/2019 - 05/31/2020 (PI)
University of Connecticut Health Center

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM. Epigenetic Age and the Risk of Incident Atrial Fibrillation. Circulation. 2021 Sep 30.View Related Profiles. PMID: 34587750; DOI: 10.1161/CIRCULATIONAHA.121.056456;
     
  2. Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A, Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N, Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E, Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI, Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G, Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK, Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV, Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue ML, Owens AT, Palmer CNA, Paré G, Perola M, Perreault LL, Portilla-Fernandez E, Psaty BM, Rice KM, Ridker PM, Romaine SPR, Roselli C, Rotter JI, Ruff CT, Sabatine MS, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL, Stefansson K, Stender S, Stott DJ, Sveinbjörnsson G, Tammesoo ML, Tardif JC, Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tuckwell D, Tyl B, Uitterlinden AG, Vaura F, Veluchamy A, Visscher PM, Völker U, Voors AA, Wang X, Wareham NJ, Weeke PE, Weiss R, White HD, Wiggins KL, Xing H, Yang J, Yang Y, Yerges-Armstrong LM, Yu B, Zannad F, Zhao F, Wilk JB, Holm H, Sattar N, Lubitz SA, Lanfear DE, Shah S, Dunn ME, Wells QS, Asselbergs FW, Hingorani AD, Dubé MP, Samani NJ, Lang CC, Cappola TP, Ellinor PT, Vasan RS, Smith JG. The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Fail. 2021 Sep 03.View Related Profiles. PMID: 34480422
     
  3. Choi SH, Jurgens SJ, Haggerty CM, Hall AW, Halford JL, Morrill VN, Weng LC, Lagerman B, Mirshahi T, Pettinger M, Guo X, Lin HJ, Alonso A, Soliman EZ, Kornej J, Lin H, Moscati A, Nadkarni GN, Brody JA, Wiggins KL, Cade BE, Lee J, Austin-Tse C, Blackwell T, Chaffin MD, Lee CJ, Rehm HL, Roselli C, Redline S, Mitchell BD, Sotoodehnia N, Psaty BM, Heckbert SR, Loos RJF, Vasan RS, Benjamin EJ, Correa A, Boerwinkle E, Arking DE, Rotter JI, Rich SS, Whitsel EA, Perez M, Kooperberg C, Fornwalt BK, Lunetta KL, Ellinor PT, Lubitz SA. Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis. Circ Genom Precis Med. 2021 Aug; 14(4):e003300.View Related Profiles. PMID: 34319147; PMCID: PMC8373440; DOI: 10.1161/CIRCGEN.120.003300;
     
  4. Sardana M, Lin H, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano N, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study. J Med Internet Res. 2021 Jun 24; 23(6):e25591.View Related Profiles. PMID: 34185019; PMCID: PMC8277303; DOI: 10.2196/25591;
     
  5. Kornej J, Hanger VA, Trinquart L, Ko D, Preis SR, Benjamin EJ, Lin H. New biomarkers from multiomics approaches: improving risk prediction of atrial fibrillation. Cardiovasc Res. 2021 Jun 16; 117(7):1632-1644.View Related Profiles. PMID: 33751041; PMCID: PMC8208748; DOI: 10.1093/cvr/cvab073;
     
  6. Yuan J, Libon DJ, Karjadi C, Ang AFA, Devine S, Auerbach SH, Au R, Lin H. Association Between the Digital Clock Drawing Test and Neuropsychological Test Performance: Large Community-Based Prospective Cohort (Framingham Heart Study). J Med Internet Res. 2021 Jun 08; 23(6):e27407.View Related Profiles. PMID: 34100766; PMCID: PMC8241432; DOI: 10.2196/27407;
     
  7. Mohanty A, Kapuria D, Canakis A, Lin H, Amat MJ, Rangel Paniz G, Placone NT, Thomasson R, Roy H, Chak E, Baffy G, Curry MP, Laine L, Rustagi T. Fresh frozen plasma transfusion in acute variceal haemorrhage: Results from a multicentre cohort study. Liver Int. 2021 08; 41(8):1901-1908.View Related Profiles. PMID: 33969607; DOI: 10.1111/liv.14936;
     
  8. Kornej J, Magnani JW, Preis SR, Soliman EZ, Trinquart L, Ko D, Benjamin EJ, Lin H. P-wave signal-averaged electrocardiography: Reference values, clinical correlates, and heritability in the Framingham Heart Study. Heart Rhythm. 2021 Sep; 18(9):1500-1507.View Related Profiles. PMID: 33989782; PMCID: PMC8419007; DOI: 10.1016/j.hrthm.2021.05.009;
     
  9. Lin H, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Kwan AC, Mitchell GF, Larson MG, Vasan RS, Cheng S. Shared Genetic and Environmental Architecture of Cardiac Phenotypes Assessed via Echocardiography: The Framingham Heart Study. Circ Genom Precis Med. 2021 04; 14(2):e003244.View Related Profiles. PMID: 33866821; PMCID: PMC8064625; DOI: 10.1161/CIRCGEN.120.003244;
     
  10. Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles. PMID: 33470944; PMCID: PMC7857942; DOI: 10.2196/24773;
     
Showing 10 of 157 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 157 publications over 17 distinct years, with a maximum of 21 publications in 2018

YearPublications
20041
20052
20069
20078
20084
20092
20114
20125
20134
201417
20155
201615
201717
201821
201913
202019
202111
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Bioinformatics
Machine learning
Microarray data analysis
Next generation sequencing
Multi-omics data integration

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

75 E. Newton St Old Evans Building
Boston MA 02118
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