Hiroshi Tokuo, MD
Research Assistant Professor
Boston University School of Medicine
Dept of Physiology & Biophysics

MD, Kumamoto University
PhD, Kumamoto University



Hiroshi Tokuo, PhD is a Research Assistant Professor of Physiology & Biophysics at the Boston University School of Medicine. Before coming to Massachusetts Dr. Tokuo worked as a dermatologist in Japan, where he is a licensed physician. Now, he trains medical students on Physiology and is a member of the American Society for Cell Biology and the American Biophysical Society. In addition to writing papers and attending conferences, Dr. Tokuo has served as Principal Investigator for two research projects.


REGULATION OF MYOSIN-X
03/09/2013 - 07/31/2015 (PI)
NIH/National Institute on Deafness & Communication Disorders
5R03DC009887-04




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Tokuo H, Bhawan J, Coluccio LM. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018 Jul 11; 8(1):10449.View Related Profiles. PMID: 29993000.
     
  2. Tokuo H, Coluccio LM. Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 2013 Sep; 24(18):2820-33.View Related Profiles. PMID: 23864705; PMCID: PMC3771945; DOI: 10.1091/mbc.E12-12-0884;.
     
  3. Watanabe TM, Tokuo H, Gonda K, Higuchi H, Ikebe M. Myosin-X induces filopodia by multiple elongation mechanism. J Biol Chem. 2010 Jun 18; 285(25):19605-14. PMID: 20392702; PMCID: PMC2885239.
     
  4. Tokuo H, Mabuchi K, Ikebe M. The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation. J Cell Biol. 2007 Oct 22; 179(2):229-38. PMID: 17954606; PMCID: PMC2064759.
     
  5. Ozawa T, Araki N, Yunoue S, Tokuo H, Feng L, Patrakitkomjorn S, Hara T, Ichikawa Y, Matsumoto K, Fujii K, Saya H. The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway. J Biol Chem. 2005 Nov 25; 280(47):39524-33. PMID: 16169856.
     
  6. Saeki N, Tokuo H, Ikebe M. BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity. J Biol Chem. 2005 Mar 18; 280(11):10128-34. PMID: 15644318.
     
  7. Tokuo H, Ikebe M. Myosin X transports Mena/VASP to the tip of filopodia. Biochem Biophys Res Commun. 2004 Jun 18; 319(1):214-20. PMID: 15158464.
     
  8. Feng L, Yunoue S, Tokuo H, Ozawa T, Zhang D, Patrakitkomjorn S, Ichimura T, Saya H, Araki N. PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin. FEBS Lett. 2004 Jan 16; 557(1-3):275-82. PMID: 14741381.
     
  9. Yunoue S, Tokuo H, Fukunaga K, Feng L, Ozawa T, Nishi T, Kikuchi A, Hattori S, Kuratsu J, Saya H, Araki N. Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras. J Biol Chem. 2003 Jul 18; 278(29):26958-69. PMID: 12730209.
     
  10. Kageshita T, Ishihara T, Tokuo H, Funasaka Y, Ichihashi M, Dong J, Nakajima M, Ono T. Widespread expression of parathyroid hormone-related peptide in melanocytic cells. Br J Dermatol. 2003 Mar; 148(3):533-8. PMID: 12653746.
     
Showing 10 of 13 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 13 publications over 10 distinct years, with a maximum of 2 publications in 2003 and 2004 and 2005

YearPublications
20001
20011
20021
20032
20042
20052
20071
20101
20131
20181
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