Investigations of
segmental uveal aqueous outflow07/01/2022 - 06/30/2024 (PI)
BrightFocus Foundation
The Role of Giant Vacuoles and Pores of Schlemm's Canal Endothelial Cells in Regulating Aqueous Outflow01/01/2020 - 03/14/2024 (Key Person / Mentor)
PI:
David L. SwainNIH/National Eye Institute5F30EY030318-03
Function of Glycocalyx in the Trabecular Outflow Pathway06/01/2020 - 05/31/2023 (PI)
NIH/National Eye Institute5R21EY028674-02
Projects for the Massachusetts Lions Eye Research Fund07/01/2014 - 05/31/2023 (PI of Sub-Project / SP)
PI:
Stephen P. Christiansen, MDMassachusetts Lions Eye Research Fund, Inc.
Testing Effect of Sustained Release vs. Cyclic Exposure of Bimatoprost on MMP/TIMP/ECM Expression by Outflow Cells05/21/2019 - 12/31/2022 (Subcontract PI)
Duke University Allergan Sales Inc
Cellular Physiology of the Aqueous Outflow Pathway09/01/2017 - 12/31/2022 (PI)
NIH/National Eye Institute5R01EY022634-09
The Role of Thrombospondin-1 in Regulating IOP07/01/2019 - 07/30/2022 (PI)
Bright Focus Foundation
Lysosomal Enzymes in Outflow Pathway Physiology and Pathophysiology06/01/2019 - 05/31/2022 (Subcontract PI)
Duke University NIH NEI5R01EY027733-04
The Mechanical Basis of Primary Open Angle Glaucoma07/01/2015 - 06/30/2021 (Subcontract PI)
Northwestern University NIH NEI5R01EY019696-10
Transmission Electron Microscope06/15/2020 - 06/14/2021 (PI)
NIH/Office of the Director1S10OD028571-01
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Effect of Netarsudil and AR-12286 on Effective Filtration Area and Morphology of the Trabecular Outflow Pathway10/15/2018 - 10/15/2019 (PI)
Aerie Pharmaceuticals, Inc.
Glycocalyx in the pores of the inner wall endothelial cells of Schlemms canal06/01/2018 - 05/31/2019 (PI)
Western Glaucoma Foundation
Lysosomal Enzymes in Outflow Pathway Physiology and Pathophysiology06/01/2018 - 05/31/2019 (Subcontract PI)
Duke University NIH NEI5R01EY027733-02
Cell-cell interactions in giant vacuole/pore formation07/01/2016 - 06/30/2018 (PI)
Bright Focus Foundation
Lysosomal Enzymes in Outflow Pathway Physiology and Pathophysiology06/01/2017 - 05/31/2018 (Subcontract PI)
Duke University NIH NEI1R01EY027733-01
Cellular Physiology of the Aqueous Outflow Pathway09/01/2016 - 08/31/2017 (PI)
NIH/National Eye Institute4R01EY022634-05
Cellular Physiology of the Aqueous Outflow Pathway09/30/2012 - 08/31/2016 (PI)
NIH/National Eye Institute5R01EY022634-04
A Mouse Giaucoma Model and Stem Cell-Based Therapy for Glaucoma07/01/2014 - 06/30/2016 (Subcontract PI)
University of Pittsburgh Bright Focus Fdn
Evaluation of the effect of an Aerie drug (AR-13324) on aqueous flow pattern and morphology in enucleated human eyes10/15/2014 - 12/30/2015 (PI)
Aerie Pharmaceuticals, Inc.
The Mechanical Basis of Primary Open Angle Glaucoma09/30/2009 - 09/29/2015 (Subcontract PI)
Northwestern University NIH NEI5R01EY019696-05
Matricellular Proteins in Trabecular Meshwork Increase Intraocular Pressure09/01/2013 - 08/31/2014 (Subcontract PI)
Case Western Reserve University NIH NEI7R01EY019654-05
Matricellular Proteins in Trabecular Meshwork09/30/2009 - 08/31/2013 (Subcontract PI)
Mass Eye and Ear Infirmary NIH NEI5R01EY019654-04
Evaluation of the Effect of An Alcon Drug on Aqueous Flow Pattern and morphology in the Outflow paathway06/01/2011 - 05/31/2013 (PI)
Alcon, Inc.
Evaluation of the Effect of an Alcon Drug on Aqueous Flow Pattern and Morphology in the Outflow Pathway using a Serum Amyloid A induced Ocular Hypertensive Mouse Model06/01/2011 - 05/31/2012 (PI)
Alcon Research Ltd
CC Ostia Herniations and Outflow Resistance in POAG Eyes09/26/2011 - 12/18/2011 (PI)
Fight for Sight, Inc.
Outflow Area and its Role in Glaucoma Pathogenesis04/01/2007 - 03/31/2009 (PI)
American Health Assistance Foundation
Hydrodynamics of Aqueous Humor Outflow03/01/2004 - 02/28/2009 (PI)
Northwestern University NIH NEI
Can Wash-out be Induced in the Human Eye to Reduce IOP?04/01/2005 - 06/30/2007 (PI)
American Health Assistance Foundation
Schelemm’s Canal Basal Lamina: A Variable Resistor?04/01/2001 - 09/30/2003 (PI)
American Health Assistance Foundation
Does Hydrodynamic Coupling Between the JCT and Inner Wall of Schlemm’s Canal Contribute to Outflow Resistance?09/01/2001 - 11/01/2002 (PI)
Glaucoma Research Foundation