Giuseppina Farina, MD, PhD
Research Assistant Professor
Boston University School of Medicine
Dept of Medicine
Rheumatology

MD, University of Rome
PhD, University of Rome




I have a broad background in clinical and research activities, with specific training and expertise in key research areas for this application. As a postdoctoral fellow I have focused my attention on translational studies, bridging clinical problems in scleroderma with molecular pathogenesis of skin, pulmonary hypertension and pulmonary fibrosis

Member
Boston University
Arthritis & Autoimmune Diseases Research Center




The Role of EBV in Monocyte Activation in Scleroderma Vasculopathy and Fibrosis
04/01/2018 - 03/31/2020 (PI)
Scleroderma Foundation


Neuroimmune Molecules in Scleroderma lung fibrosis
04/01/2016 - 03/31/2020 (Subcontract PI)
Yale University NIH NHLBI
5R01HL125850-04

Innate Immune Modulation in Scleroderma Fibroblasts by EBV Infection
01/15/2014 - 07/15/2016 (PI)
Scleroderma Foundation


Interplay between Type I IFN and TGF-beta signaling in systematic sclerosis
04/01/2012 - 03/31/2015 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R03AR062721-03



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Gonnella R, Dimarco M, Farina GA, Santarelli R, Valia S, Faggioni A, Angeloni A, Cirone M, Farina A. BFRF1 protein is involved in EBV-mediated autophagy manipulation. Microbes Infect. 2020 Aug 31. PMID: 32882412
     
  2. Dreyfus DH, Farina A, Farina GA. Correction to: Molecular mimicry, genetic homology, and gene sharing proteomic "molecular fingerprints" using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease. Immunol Res. 2019 Oct; 67(4-5):460. PMID: 31773489
     
  3. Dreyfus DH, Farina A, Farina GA. Molecular mimicry, genetic homology, and gene sharing proteomic "molecular fingerprints" using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease. Immunol Res. 2018 12; 66(6):686-695. PMID: 30552620
     
  4. Farina A, Peruzzi G, Lacconi V, Lenna S, Quarta S, Rosato E, Vestri AR, York M, Dreyfus DH, Faggioni A, Morrone S, Trojanowska M, Farina GA. Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes. Arthritis Res Ther. 2017 Feb 28; 19(1):39.View Related Profiles. PMID: 28245863; DOI: 10.1186/s13075-017-1237-9;
     
  5. Yadav S, Libotte F, Buono E, Valia S, Farina GA, Faggioni A, Farina A. EBV early lytic protein BFRF1 alters emerin distribution and post-translational modification. Virus Res. 2017 03 15; 232:113-122. PMID: 28238874
     
  6. Farina A, Farina GA. Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. Curr Rheumatol Rep. 2016 Jan; 18(1):1. PMID: 26700911; DOI: 10.1007/s11926-015-0552-x;
     
  7. Lenna S, Assassi S, Farina GA, Mantero JC, Scorza R, Lafyatis R, Farber HW, Trojanowska M. The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients. Arthritis Res Ther. 2015; 17:363.View Related Profiles. PMID: 26669670; PMCID: PMC4704539; DOI: 10.1186/s13075-015-0881-1;
     
  8. Rice LM, Padilla CM, McLaughlin SR, Mathes A, Ziemek J, Goummih S, Nakerakanti S, York M, Farina G, Whitfield ML, Spiera RF, Christmann RB, Gordon JK, Weinberg J, Simms RW, Lafyatis R. Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients. J Clin Invest. 2015 Jul 1; 125(7):2795-807.View Related Profiles. PMID: 26098215; PMCID: PMC4563675; DOI: 10.1172/JCI77958;
     
  9. van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR. Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med. 2014 Jan 30; 370(5):433-43.View Related Profiles. PMID: 24350901; PMCID: PMC4040466; DOI: 10.1056/NEJMoa1114576;
     
  10. Farina A, Cirone M, York M, Lenna S, Padilla C, McLaughlin S, Faggioni A, Lafyatis R, Trojanowska M, Farina GA. Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma. J Invest Dermatol. 2014 Apr; 134(4):954-64.View Related Profiles. PMID: 24129067; PMCID: PMC3961515; DOI: 10.1038/jid.2013.423;
     
Showing 10 of 29 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 17 distinct years, with a maximum of 5 publications in 2010 and 2013

YearPublications
19991
20011
20022
20061
20071
20081
20091
20105
20111
20122
20135
20152
20161
20172
20181
20191
20201

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

innate immunity

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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