Fuzhong Qin, MD, PhD
Research Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Datong Medical College
PhD, Shanxi Medical University




Dr. Qin is a Professor of Cardiovascular Medicine at the Boston University School of Medicine. He is the Director of the Physiological Core Laboratory in the Myocardial Biology Unit / Cardiovascular Medicine Section. He is also the Director of the Echocardiography Core in the Whitaker Cardiovascular Institute. Dr. Qin’s research has focused on the cellular and molecular mechanisms of myocardial remodeling and pathophysiology of heart failure, and in particular, the role of reactive oxygen species. They are investigating the effects of catalase overexpression or pharmacological intervention on left ventricular remodeling and dysfunction in transgenic mouse models of heart failure induced by G(alpha)q overexpression as well as mouse models of human heart failure induced by chronic pressure overload or myocardial infarction and diet-induced metabolic heart disease. Dr. Qin has expertise (scientific) in a) oxidative stress, myocyte apoptosis, and apoptosis-related signal transduction pathways, b) oxidative stress, oxidative protein modifications of SERCA2, intracellular calcium transients and myocyte contractile function, c) oxidative stress, myocyte hypertrophy and myocardial diastolic dysfunction. He also has expertise (technical) in the animal models (mice, rats, rabbits and dogs) of myocardial ischemia / reperfusion, coronary artery ligation-induced myocardial infarction and failure, and ascending aortic constriction-induced myocardial hypertrophy and failure, conventional echocardiography, mitral inflow and tissue Doppler echocardiography, in vivo hemodynamics, ex vivo Langendorff isolated heart perfusion, measurements of intracellular calcium concentration and contractile function in isolated myocytes, myocyte culture, histological measurements and biochemical measurements.

Member
Boston University
Whitaker Cardiovascular Institute


Boston Medical Center


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Croteau D, Qin F, Chambers JM, Kallick E, Luptak I, Panagia M, Pimentel DR, Siwik DA, Colucci WS. Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease. JACC Basic Transl Sci. 2020 Sep; 5(9):916-927.View Related Profiles. PMID: 33015414
     
  2. Luptak I, Croteau D, Valentine C, Qin F, Siwik DA, Remick DG, Colucci WS, Hobai IA. Myocardial Redox Hormesis Protects the Heart of Female Mice in Sepsis. Shock. 2019 07; 52(1):52-60.View Related Profiles. PMID: 30102640
     
  3. Luptak I, Qin F, Sverdlov AL, Pimentel DR, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease. Antioxid Redox Signal. 2019 09 01; 31(7):539-549.View Related Profiles. PMID: 31088291
     
  4. Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. J Mol Cell Cardiol. 2018 03; 116:106-114.View Related Profiles. PMID: 29409987; DOI: 10.1016/j.yjmcc.2018.01.017;
     
  5. Ho JE, Rahban Y, Sandhu H, Hiremath PG, Ayalon N, Qin F, Perez AJ, Downing J, Gopal DM, Cheng S, Colucci WS. Preclinical Alterations in Myocardial Microstructure in People with Metabolic Syndrome. Obesity (Silver Spring). 2017 Sep; 25(9):1516-1522.View Related Profiles. PMID: 28737258; DOI: 10.1002/oby.21936;
     
  6. Xu XJ, Babo E, Qin F, Croteau D, Colucci WS. Short-term caloric restriction in db/db mice improves myocardial function and increases high molecular weight (HMW) adiponectin. IJC Metab Endocr. 2016 Dec; 13:28-34.View Related Profiles. PMID: 27942464
     
  7. Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles. PMID: 26755553; PMCID: PMC4859372; DOI: 10.1161/JAHA.115.002555;
     
  8. Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles. PMID: 26722122; PMCID: PMC4859355; DOI: 10.1161/JAHA.115.002277;
     
  9. Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Wilson S C, Edward J M. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. J Mol Cell Cardiol. 2015 Feb; 79:275-83.View Related Profiles. PMID: 25497302; PMCID: PMC4301992; DOI: 10.1016/j.yjmcc.2014.12.001;
     
  10. Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1453-63.View Related Profiles. PMID: 24633550; PMCID: PMC4024717; DOI: 10.1152/ajpheart.00084.2014;
     
Showing 10 of 29 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 18 distinct years, with a maximum of 4 publications in 2004

YearPublications
20021
20032
20044
20051
20061
20071
20093
20101
20112
20122
20131
20142
20151
20162
20171
20181
20192
20201

Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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