Frederick Ruberg | Profiles RNS

Frederick L. Ruberg, MD - Chief, Cardiovascular Medicine

Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Cardiovascular Medicine

MD, University of Pennsylvania School of Medicine
BA, Haverford College

Pronouns: he/him/his

Websites

	Boston University School of Medicine Profile
	Boston Medical Center Provider Profile
	ResearchGate

ORCID : 0000-0002-6424-4413

Frederick L. Ruberg, MD is the Thomas J. Ryan Professor of Cardiovascular Medicine and Professor of Radiology at Boston University (BU) Chobanian & Avedisian School of Medicine and Chief, Section of Cardiovascular Medicine at Boston Medical Center (BMC). Dr. Ruberg attended the University of Pennsylvania Perelman School of Medicine, completed internal medicine training at Brigham and Women’s Hospital, cardiovascular disease fellowship at Boston Medical Center/Boston University School of Medicine, followed by a fellowship in cardiovascular magnetic resonance (CMR) imaging at Beth Israel Deaconess Medical Center in Boston. Committed to research mentorship, he co-directs Workforce Development for the Boston University Clinical and Translational Science Institute (CTSI) and serves as Senior Associate Editor of Circulation: Cardiovascular Imaging. Dr. Ruberg is a Fellow of the American Heart Association and a member of the Association of University Cardiologists. His clinical and research expertise primarily involves cardiac imaging and infiltrative heart disease focused on improving the recognition and care of patients with cardiac amyloidosis, particularly that owing to ATTR and the hereditary genetic TTR variant Val122Ile (or V142I). He is an investigator on numerous NIH-funded awards including co-PI of the $7.2m NHLBI-funded Screening for Cardiac Amyloidosis with Nuclear Imaging (SCAN-MP, R01 HL139671) study. An active clinical cardiologist at the BU Amyloidosis Center, he has also contributed and co-directed numerous collaborative clinical guidelines initiatives, including mostly recently the 2023 the ACC Expert Consensus Decision Pathway document on The Comprehensive Multidisciplinary Care of Patient with Cardiac Amyloidosis. Dr. Ruberg has been recognized with mentorship (2017) and citizenship (2022) awards from the BU Department of Medicine.

Professor
Boston University Chobanian & Avedisian School of Medicine
Radiology

Member
Boston University
Whitaker Cardiovascular Institute

Member
Boston University
Amyloidosis Center

Program Director
Boston University Chobanian & Avedisian School of Medicine
Clinical and Translational Science Institute
Pilot Translational & Clinical Studies Program

The Boston University Clinical and Transitional Science Institute
04/15/2020 - 03/31/2025 (Key Person)
PI: Megan H. Bair-Merritt, MD, MSCE
NIH/National Center for Advancing Translational Sciences
5UL1TR001430-09

Molecular Imaging of Primary Amyloid Cardiomyopathy
04/01/2017 - 03/31/2020 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
5R01HL130563-04

A Multi-Center Study of an ECG-AI Software as a Medical Device to Detect Cardiac Amyloidosis
03/11/2024 - 03/31/2027 (PI)
Anumana, Inc.

AG10-501: A Phase 3, Randomized, Multicenter, Double-Blind, Placebo Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial
03/05/2025 - 03/05/2027 (PI)
Eidos Therapeutics Inc.

ATTR Database Pilot
10/01/2024 - 12/31/2026 (Subcontract PI)
PI: Frederick L. Ruberg, MD - Chief, Cardiovascular Medicine
TriNetX, LLC Astrazeneca Pharm

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
06/01/2023 - 02/28/2026 (Subcontract PI)
PI: Frederick L. Ruberg, MD - Chief, Cardiovascular Medicine
Trustees of Columbia University NIH NIA
1R01AG081582-01

Boston University/Boston Medical Center Research Fellowship in Cardiac Amyloidosis
07/01/2023 - 06/30/2025 (PI)
Pfizer, Inc

Scan-MP (Screening fro cardiac amyloidosis with nuclear imaging in minority…
05/01/2019 - 02/28/2025 (Subcontract PI)
PI: Frederick L. Ruberg, MD - Chief, Cardiovascular Medicine
The Trustees of Colombia University in the City of New York dba Colombia University NIH NHLBI

Gadolinium-Free Myocardial Scar and Fibrosis Imaging with Cardiac MRI
07/01/2020 - 06/30/2024 (Subcontract PI)
PI: Frederick L. Ruberg, MD - Chief, Cardiovascular Medicine
Beth Israel Deaconess Medical Center NIH NHLBI
1R01HL154744-01

Screening for ATTR Amyloidosis among patients undergoing lumbar spinal stenosis decompression…
02/11/2020 - 11/30/2023 (PI)
Akcea Therapeutics,Inc

2021 Transthyretin Cardiac Amyloidosis Fellowship
10/14/2021 - 10/25/2023 (PI)
Pfizer, Inc

Cardiac Amyloidosis Fellowship
01/01/2020 - 02/14/2023 (PI)
Pfizer, Inc

Showing 10 of 22 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2025	Screening for Cardiac Amyloidosis with a Blood Biomarker in Minority Populations – SCABB-MP	1R01HL177670-01
2023	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-05
2022	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-04
2021	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-03	5
2020	SCAN-MP (Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations) COVID-19 Suppplement	3R01HL139671-02S1	5
2020	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-02	5
2019	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	1R01HL139671-01A1	5
2016	Serum biomarker identification of cardiac amyloidosis in elderly African Americans.	5R21AG050206-02	9
2015	Serum biomarker identification of cardiac amyloidosis in elderly African Americans.	1R21AG050206-01	9

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Slivnick JA, Hawkes W, Oliveira J, Woodward G, Akerman A, Gomez A, Hamza I, Desai VK, Barrett-O'Keefe Z, Grogan M, Dispenzieri A, Scott CG, Davison HN, Cotella J, Maurer M, Helmke S, Scherrer-Crosbie M, Soltani M, Goyal A, Zareba KM, Cheng RK, Kirkpatrick JN, Kitano T, Takeuchi M, Tiemi Hotta V, Campos Vieira ML, Elissamburu P, Ronderos RE, Prado A, Koutroumpakis E, Deswal A, Pursnani A, Sarswat N, Patel AR, Addetia K, Ruberg FL, Randazzo M, Asch FM, O'Driscoll J, Al-Roub N, Strom JB, Kidd L, Cuddy S, Upton R, Lang RM, Pellikka PA. Cardiac amyloidosis detection from a single echocardiographic video clip: a novel artificial intelligence-based screening tool. Eur Heart J. 2025 Oct 22; 46(40):4090-4101. PMID: 40631729; PMCID: PMC12539910; DOI: 10.1093/eurheartj/ehaf387;

Wees IR, Ayers C, Ruberg FL, Maurer MS, Brailovsky Y, Stern LK, Griffin JM, Khouri MG, Roth LR, Grodin JL. Clinical Implications of the P.V142I TTR Variant: Insights From CARS. JACC Heart Fail. 2025 Oct 09; 102704. PMID: 41074899; DOI: 10.1016/j.jchf.2025.102704;

Ruberg FL, Teruya S, Helmke S, Smiley DA, Fine D, Kurian D, Raiszadeh F, Prokaeva T, Spencer B, Wong S, Pandey S, Blaner WS, DeLuca A, Johnson LL, Kinkhabwala MP, Leb J, Mintz A, LaValley MP, Einstein AJ, Cohn E, Gallegos C, Murtagh G, Kelly JW, Miller EJ, Maurer MS. Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart Failure. JAMA Cardiol. 2025 Oct 01; 10(10):1034-1043.View Related Profiles.

Ruberg, Frederick
LaValley, Michael
Pandey, Shivda
Prokaeva, Tatiana

PMID: 40928765; PMCID: PMC12423950; DOI: 10.1001/jamacardio.2025.2948;

Masri A, Judge DP, Ruberg FL, Gillmore JD, Grodin JL, Obici L, Maurer MS, Fontana M, Poulsen SH, van der Meer P, Cheng RK, Cuddy SAM, Ambardekar AV, Xiong K, Cao X, Murtagh G, Siddhanti S, Castaño A, Tamby JF, Fox JC, Alexander KM, Witteles R. Effect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CM: Exploratory Analysis From ATTRibute-CM. J Am Coll Cardiol. 2025 Sep 28. PMID: 41143759; DOI: 10.1016/j.jacc.2025.09.013;

Benz DC, Clerc OF, Cuddy SAM, Singh V, Kijewski MF, Bianchi G, Yee AJ, Ruberg FL, Jerosch-Herold M, Kwong RY, Di Carli MF, Liao R, Falk RH, Dorbala S. Changes in Myocardial Light Chain Amyloid Burden After Plasma Cell Therapy. JACC Cardiovasc Imaging. 2025 Dec; 18(12):1363-1374. PMID: 40938234

McMenamin KJ, Ruberg FL. High-Intensity Exercise, Fibrosis, and Ventricular Arrhythmias: How Much Is Too Much? Circ Cardiovasc Imaging. 2025 Aug; 18(8):e018716.View Related Profiles.

Ruberg, Frederick
McMenamin, Katie

PMID: 40675175; DOI: 10.1161/CIRCIMAGING.125.018716;

Islam SJ, Teruya S, Fine D, Sabogal N, Fils S, Ullah I, Sanchorawala A, Miller E, Gallegos C, DE Freitas C, Kurian D, Ionescu N, Janvier I, Raiszadeh F, Benjamin EJ, Magnani JW, Maurer MS, Ruberg FL. Health Literacy and Physical Function Among Older Black and Hispanic Individuals With Heart Failure. J Card Fail. 2025 Jul 12.View Related Profiles.

Sanchorawala, Anya
Benjamin, Emelia
Ruberg, Frederick
Islam, Shabatun

PMID: 40659241

Regan JA, Kittleson MM, Khouri MG, Ruberg FL, Selvaraj S. Serum Transthyretin as a Biomarker of Treatment Response in ATTR Cardiomyopathy. J Am Coll Cardiol. 2025 May 27; 85(20):1924-1926. PMID: 40398972; PMCID: PMC12163915; DOI: 10.1016/j.jacc.2025.04.014;

Siddiqi OK, Ruberg FL, Gopal DM. Impact of Vutrisiran on Functional Capacity and Quality of Life in ATTR Cardiomyopathy: HELIOS-B Analysis. J Am Coll Cardiol. 2025 May 27; 85(20):1956-1958.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Siddiqi, Omar

PMID: 40398974

Griffin JM, Grodin JL, Ruberg FL, Masri A, Hanna M, Maurer MS. Current Landscape of Therapies for Transthyretin Amyloid Cardiomyopathy. JACC Heart Fail. 2025 May; 13(5):685-694. PMID: 40335224; PMCID: PMC12089935; DOI: 10.1016/j.jchf.2025.03.017;

Showing 10 of 161 results. Show More

Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Singh Bawa P, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. Amyloid. 2025 Jun; 32(2):179-192.View Related Profiles.

Staron, Andrew
Edwards, Camille
Klimtchuk, Elena
Ruberg, Frederick
Morgan, Gareth
Murphy, George
Ferri, Grace
Prokaeva, Tatiana
Sanchorawala, Vaishali

PMID: 40134188; DOI: 10.1080/13506129.2025.2478397;

Dorbala S, Adigun R, Alexander KM, Brambatti M, Cuddy SAM, Dispenzieri A, Dunnmon P, Emdin M, Abou Ezzeddine OF, Falk RH, Fontana M, Grodin JL, Guthrie S, Jerosch-Herold M, Hofling AA, Hsu K, Lin G, Masri A, Maurer MS, Mittmann C, Prasad K, Quarta CC, Race JM, Rajendran JG, Ruberg FL, Sachdev V, Sanchorawala V, Signorovitch J, Sirac C, Soman P, Sorensen J, Sperry BW, Stephens AW, Stockbridge NL, Vest J, Wall JS, Wechalekar A, Welsh C, Lousada I. Development of Imaging Endpoints for Clinical Trials in AL and ATTR Amyloidosis: Proceedings of the Amyloidosis Forum. JACC Cardiovasc Imaging. 2025 May; 18(5):602-617.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 39985507; PMCID: PMC12161488; DOI: 10.1016/j.jcmg.2024.11.003;

Cheng RK, Leedy D, Ruberg FL. Can Outpatient Worsening Heart Failure Serve as an Endpoint in Clinical Trials of Transthyretin Amyloidosis? J Am Coll Cardiol. 2025 Feb 25; 85(7):762-765. PMID: 39846939; DOI: 10.1016/j.jacc.2024.10.126;

Madhani A, Kotturu N, Fine D, Alreshq R, Saade A, Tannoury T, Tannoury C, Ruberg FL. Spinal amyloid deposits are common among older patients undergoing spinal stenosis decompression surgery. J Gen Fam Med. 2025 May; 26(3):222-230.View Related Profiles.

Madhani, Avni
Tannoury, Chadi
Ruberg, Frederick
Tannoury, Tony

PMID: 40291058; PMCID: PMC12022420; DOI: 10.1002/jgf2.766;

Fontana M, Ioannou A, Cuddy S, Dorbala S, Masri A, Moon JC, Singh V, Clerc O, Hanna M, Ruberg F, Grogan M, Emdin M, Gillmore J. The Last Decade in Cardiac Amyloidosis: Advances in Understanding Pathophysiology, Diagnosis and Quantification, Prognosis, Treatment Strategies, and Monitoring Response. JACC Cardiovasc Imaging. 2025 Apr; 18(4):478-499. PMID: 39797879; PMCID: PMC12273739; DOI: 10.1016/j.jcmg.2024.10.011;

Chan N, Einstein AJ, Teruya S, Rodriguez C, Helmke S, Cuomo M, Santana D, Castillo M, Smiley D, Sabogal N, Lamour S, Winburn M, Fine D, de Freitas C, Kattan CG, Miller EJ, Maurer MS, Ruberg FL. The Impact of Active Ascertainment on Sex-Specific Differences in the Prevalence and Phenotype of Transthyretin Cardiac Amyloidosis: The Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations Study. Am J Cardiol. 2025 Feb 15; 237:60-64. PMID: 39581521; PMCID: PMC11761373; DOI: 10.1016/j.amjcard.2024.11.019;

Clerc OF, Vijayakumar S, Cuddy SAM, Bianchi G, Canseco Neri J, Taylor A, Benz DC, Datar Y, Kijewski MF, Yee AJ, Ruberg FL, Liao R, Falk RH, Sanchorawala V, Dorbala S. Functional Status and Quality of Life in Light-Chain Amyloidosis: Advanced Imaging, Longitudinal Changes, and Outcomes. JACC Heart Fail. 2024 Dec; 12(12):1994-2006.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali
Datar, Yesh

PMID: 39243245; PMCID: PMC12042710; DOI: 10.1016/j.jchf.2024.07.007;

Urina-Jassir M, Teruya S, Blaner WS, Brun PJ, Prokaeva T, Tsai FJ, Kelly JW, Maurer MS, Ruberg FL. Differential Association of Transthyretin Stability with Variant and Wild-Type Transthyretin Amyloid Cardiomyopathy: The SCAN-MP Study. JACC Heart Fail. 2024 Dec; 12(12):2113-2115.View Related Profiles.

Ruberg, Frederick
Prokaeva, Tatiana

PMID: 39115519; PMCID: PMC11742182; DOI: 10.1016/j.jchf.2024.06.014;

Clerc OF, Datar Y, Cuddy SAM, Bianchi G, Taylor A, Benz DC, Robertson M, Kijewski MF, Jerosch-Herold M, Kwong RY, Ruberg FL, Liao R, Di Carli MF, Falk RH, Dorbala S. Prognostic Value of Left Ventricular 18F-Florbetapir Uptake in Systemic Light-Chain Amyloidosis. JACC Cardiovasc Imaging. 2024 Aug; 17(8):911-922.View Related Profiles.

Ruberg, Frederick
Datar, Yesh

PMID: 39001731; PMCID: PMC11975406; DOI: 10.1016/j.jcmg.2024.05.002;

Clerc OF, Cuddy SAM, Jerosch-Herold M, Benz DC, Katznelson E, Canseco Neri J, Taylor A, Kijewski MF, Bianchi G, Ruberg FL, Di Carli MF, Liao R, Kwong RY, Falk RH, Dorbala S. Myocardial Characteristics, Cardiac Structure, and Cardiac Function in Systemic Light-Chain Amyloidosis. JACC Cardiovasc Imaging. 2024 Nov; 17(11):1271-1286. PMID: 39001736; PMCID: PMC12009672; DOI: 10.1016/j.jcmg.2024.05.004;

Thel MC, Cochran JD, Teruya S, Hayashi O, Xie CR, Srinivasan AR, Chavkin NW, Arai Y, Sano S, Mirabal Santos A, De Los Santos J, Fine D, Sabogal N, Ullah I, Helmke S, Rodriguez C, Prokaeva T, Foster RH, Spencer BH, Izumiya Y, Maurer MS, Walsh K, Ruberg FL. Mosaic Loss of the Y Chromosome Is Enriched in Patients With Wild-Type Transthyretin Cardiac Amyloidosis and Associated With Increased Mortality. Circ Heart Fail. 2024 Aug; 17(8):e011681.View Related Profiles.

Ruberg, Frederick
Chavkin, Nicholas
Prokaeva, Tatiana

PMID: 38853760; PMCID: PMC11335443; DOI: 10.1161/CIRCHEARTFAILURE.124.011681;

Maurer MS, Soman P, Hernandez A, Garcia-Pavia P, Signorovitch J, Wei LJ, Hanna M, Ruberg FL, Kittleson M, Kazi D, Dorbala S, Hsu K, Lousada I, Adigun R, Dunnmon P, Kelly J, Gillmore J. Advancing Transthyretin Amyloidosis Drug Development in an Evolving Treatment Landscape: Amyloidosis Forum Meeting Proceedings. Adv Ther. 2024 Jul; 41(7):2723-2742. PMID: 38833142; PMCID: PMC11334214; DOI: 10.1007/s12325-024-02891-0;

Maurer MS, Miller EJ, Ruberg FL. Addressing Health Disparities-The Case for Variant Transthyretin Cardiac Amyloidosis Grows Stronger. JAMA. 2024 Jun 04; 331(21):1809-1811. PMID: 38734953

Katznelson E, Jerosch-Herold M, Cuddy SAM, Clerc OF, Benz DC, Taylor A, Rao S, Kijewski MF, Liao R, Landau H, Yee AJ, Ruberg FL, Di Carli MF, Falk RH, Kwong RY, Dorbala S. Mechanisms of left ventricular systolic dysfunction in light chain amyloidosis: a multiparametric cardiac MRI study. Front Cardiovasc Med. 2024; 11:1371810. PMID: 38873265; PMCID: PMC11169788; DOI: 10.3389/fcvm.2024.1371810;

Wardhere A, Bampatsias D, Cohn E, Fine D, Freitas C, Gallegos C, Helmke S, Ionescu N, Ivrose J, Rodriguez C, Sabogal N, Fils S, Henry T, Teruya S, Ullah I, Kurian D, Raiszadeh F, Miller EJ, Ruberg FL, Maurer MS. Unlocking Diversity in Cardiovascular Clinical Research: Lessons from the Screening for Cardiac Amyloidosis With Nuclear Imaging in a Minority Populations Study. J Card Fail. 2024 Nov; 30(11):1507-1511. PMID: 38740174; PMCID: PMC11551251; DOI: 10.1016/j.cardfail.2024.04.019;

Datar Y, Clerc OF, Cuddy SAM, Kim S, Taylor A, Neri JC, Benz DC, Bianchi G, Yee AJ, Sanchorawala V, Ruberg FL, Landau H, Liao R, Kijewski MF, Jerosch-Herold M, Kwong RY, Di Carli MF, Falk RH, Dorbala S. Quantification of right ventricular amyloid burden with 18F-florbetapir positron emission tomography/computed tomography and its association with right ventricular dysfunction and outcomes in light-chain amyloidosis. Eur Heart J Cardiovasc Imaging. 2024 Apr 30; 25(5):687-697.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali
Datar, Yesh

PMID: 38193678; PMCID: PMC11057921; DOI: 10.1093/ehjci/jead350;

Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Bawa PS, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. bioRxiv. 2024 Mar 16.View Related Profiles.

Staron, Andrew
Edwards, Camille
Klimtchuk, Elena
Ruberg, Frederick
Murphy, George
Ferri, Grace
Prokaeva, Tatiana
Sanchorawala, Vaishali

PMID: 38558967; PMCID: PMC10980073; DOI: 10.1101/2024.03.14.584987;

Ruberg FL, Maurer MS. Cardiac Amyloidosis Due to Transthyretin Protein: A Review. JAMA. 2024 Mar 05; 331(9):778-791. PMID: 38441582; PMCID: PMC11167454; DOI: 10.1001/jama.2024.0442;

Datar Y, Cuddy SAM, Ovsak G, Giblin GT, Maurer MS, Ruberg FL, Arnaout R, Dorbala S. Myocardial Texture Analysis of Echocardiograms in Cardiac Transthyretin Amyloidosis. J Am Soc Echocardiogr. 2024 May; 37(5):570-573.View Related Profiles.

Ruberg, Frederick
Datar, Yesh

PMID: 38395112; PMCID: PMC11070288; DOI: 10.1016/j.echo.2024.02.005;

Ruberg FL, Gropler RJ. In This Issue of the Journal. Circ Cardiovasc Imaging. 2024 Feb; 17(2):e016675. PMID: 38377239

Chan N, Einstein AJ, Griffin JM, Rosenblum H, Teruya S, Cuomo M, De Los Santos J, DeLuca A, Johnson LL, Kinkhabwala MP, Leb JS, Mintz A, Fine D, Helmke S, Muralidhar V, Pandey S, Sabogal N, Saith SE, Winburn M, Smiley D, Miller EJ, Ruberg FL, Maurer MS. Prevalence and significance of extracardiac uptake on pyrophosphate imaging in the SCAN-MP study: the first 379 cases. J Nucl Cardiol. 2023 Dec; 30(6):2531-2539.View Related Profiles.

Ruberg, Frederick
Pandey, Shivda

PMID: 38245059; DOI: 10.1007/s12350-023-03310-7;

Stern LK, Grodin JL, Maurer MS, Ruberg FL, Patel AR, Khouri MG, Roth LR, Aras MA, Bhardwaj A, Bhattacharya P, Brailovsky Y, Drachman BM, Ebong IA, Fine NM, Gaggin H, Gopal D, Griffin J, Judge D, Kim P, Mitchell J, Mitter SS, Mohan RC, Ramos H, Reyentovich A, Sheikh FH, Sperry B, Carter S, Urey M, Vaishnav J, Vest AR, Kittleson MM, Patel JK. The Cardiac Amyloidosis Registry Study (CARS): Rationale, Design and Methodology. J Card Fail. 2024 May; 30(5):669-678.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick

PMID: 37907148; DOI: 10.1016/j.cardfail.2023.09.016;

Gustine JN, Staron A, Mendelson L, Joshi T, Gopal DM, Siddiqi OK, Ruberg FL, Sanchorawala V. Predictors of treatment response and survival outcomes in patients with advanced cardiac AL amyloidosis. Blood Adv. 2023 Oct 24; 7(20):6080-6091.View Related Profiles.

Staron, Andrew
Gopal, Deepa
Ruberg, Frederick
Mendelson, Lisa
Siddiqi, Omar
Joshi, Tracy
Sanchorawala, Vaishali

PMID: 37581513; PMCID: PMC10582303; DOI: 10.1182/bloodadvances.2023010324;

Clerc OF, Cuddy SAM, Jerosch-Herold M, Benz DC, Katznelson E, Canseco Neri J, Taylor A, Kijewski MF, Bianchi G, Ruberg FL, Di Carli MF, Liao R, Kwong RY, Falk RH, Dorbala S. Myocardial Characterization for Early Diagnosis, Treatment Response Monitoring, and Risk Assessment in Systemic Light-Chain Amyloidosis. medRxiv. 2023 Oct 05. PMID: 37873250; PMCID: PMC10593053; DOI: 10.1101/2023.10.04.23296572;

Clerc OF, Datar Y, Cuddy SA, Bianchi G, Taylor A, Benz DC, Robertson M, Kijewski MF, Jerosch-Herold M, Kwong RY, Ruberg FL, Liao R, Di Carli MF, Falk RH, Dorbala S. Prognostic Value of Left Ventricular 18 F-Florbetapir Uptake in Systemic Light-Chain Amyloidosis. medRxiv. 2023 Sep 14.View Related Profiles.

Ruberg, Frederick
Datar, Yesh

PMID: 37745589; PMCID: PMC10516059; DOI: 10.1101/2023.09.13.23295520;

Cochran JD, Yura Y, Thel MC, Doviak H, Polizio AH, Arai Y, Arai Y, Horitani K, Park E, Chavkin NW, Kour A, Sano S, Mahajan N, Evans M, Huba M, Naya NM, Sun H, Ban YH, Hirschi KK, Toldo S, Abbate A, Druley TE, Ruberg FL, Maurer MS, Ezekowitz JA, Dyck JRB, Walsh K. Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction. Circulation. 2023 Oct 10; 148(15):1165-1178.View Related Profiles.

Ruberg, Frederick
Chavkin, Nicholas

PMID: 37681311; PMCID: PMC10575571; DOI: 10.1161/CIRCULATIONAHA.123.064170;

Madhani A, Sabogal N, Massillon D, Paul LD, Rodriguez C, Fine D, Helmke S, Winburn M, Kurian D, Raiszadeh F, Teruya S, Cohn E, Einstein AJ, Miller EJ, Connors LH, Maurer MS, Ruberg FL. Clinical Penetrance of the Transthyretin V122I Variant in Older Black Patients With Heart Failure: The SCAN-MP (Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations) Study. J Am Heart Assoc. 2023 Aug; 12(15):e028973.View Related Profiles.

Madhani, Avni
Ruberg, Frederick
Connors, Lawreen
Paul, Ludwine

PMID: 37486082; PMCID: PMC10492994; DOI: 10.1161/JAHA.122.028973;

Ruberg, Frederick
Pandey, Shivda

PMID: 37311914

Ruberg FL. Finally Getting to the Heart of the Matter: Imaging Multiorgan Treatment Response in AL Amyloidosis. JACC Cardiovasc Imaging. 2023 Aug; 16(8):1053-1055. PMID: 37269271

Ruberg FL, Blaner WS, Chiuzan C, Connors LH, Einstein AJ, Fine D, Helmke S, Kurian D, Pandey S, Raiszadeh F, Rodriguez C, Sabogal N, Teruya S, Winburn M, Chung WK, Cohn E, Miller EJ, Kelly JW, Maurer MS. Design and Rationale the SCAN-MP (Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations) Study. J Am Heart Assoc. 2023 Apr 18; 12(8):e028534.View Related Profiles.

Ruberg, Frederick
Connors, Lawreen
Pandey, Shivda

PMID: 37066788; PMCID: PMC10227254; DOI: 10.1161/JAHA.122.028534;

Amyar A, Fahmy AS, Guo R, Nakata K, Sai E, Rodriguez J, Cirillo J, Pareek K, Kim J, Judd RM, Ruberg FL, Weinsaft JW, Nezafat R. Scanner-Independent MyoMapNet for Accelerated Cardiac MRI T1 Mapping Across Vendors and Field Strengths. J Magn Reson Imaging. 2024 Jan; 59(1):179-189. PMID: 37052580; PMCID: PMC11218141; DOI: 10.1002/jmri.28739;

Edmiston JB, Cohn EG, Teruya SL, Sabogal N, Massillon D, Muralidhar V, Rodriguez C, Helmke S, Fine D, Winburn M, Chiuzan C, Hod EA, Raiszadeh F, Kurian D, Maurer MS, Ruberg FL. Clinical and social determinants of health features of SARS-CoV-2 infection among Black and Caribbean Hispanic patients with heart failure: The SCAN-MP Study. PLoS One. 2023; 18(3):e0283730. PMID: 36996149; PMCID: PMC10062570; DOI: 10.1371/journal.pone.0283730;

Pandey S, Teruya S, Rodriguez C, Deluca A, Kinkhabwala M, Johnson LL, Fine D, Sabogal N, Winburn M, Castillo M, Bhatia K, Malkovskaya R, Raiszadeh F, Kurian D, Miller EJ, Einstein AJ, Maurer MS, Ruberg FL. Diagnostic performance characteristics of planar quantitative and semi-quantitative parameters of Tc99m pyrophosphate (PYP) imaging for diagnosis of transthyretin (ATTR) cardiac amyloidosis: the SCAN-MP study. J Nucl Cardiol. 2023 Aug; 30(4):1414-1419.View Related Profiles.

Ruberg, Frederick
Pandey, Shivda

PMID: 36823486; PMCID: PMC11268194; DOI: 10.1007/s12350-023-03203-9;

Staron A, Mendelson LM, Joshi T, Ruberg FL, Sanchorawala V. Factors affecting the accuracy of amyloidosis identification and referral to a specialty centre. Amyloid. 2023 Sep; 30(3):297-302.View Related Profiles.

Staron, Andrew
Ruberg, Frederick
Mendelson, Lisa
Joshi, Tracy
Sanchorawala, Vaishali

PMID: 36718932; DOI: 10.1080/13506129.2023.2171787;

Kittleson MM, Ruberg FL, Ambardekar AV, Brannagan TH, Cheng RK, Clarke JO, Dember LM, Frantz JG, Hershberger RE, Maurer MS, Nativi-Nicolau J, Sanchorawala V, Sheikh FH. 2023 ACC Expert Consensus Decision Pathway on Comprehensive Multidisciplinary Care for the Patient With Cardiac Amyloidosis: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2023 Mar 21; 81(11):1076-1126.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 36697326; DOI: 10.1016/j.jacc.2022.11.022;

Valente CJ, Chiuzan C, Alreshq R, Blot T, Fine D, Helmke S, Rodriguez C, Sabogal N, Teruya S, Winburn M, Kurian D, Raiszadeh F, Maurer MS, Ruberg FL. Physical Performance in Black and Hispanic Outpatients With Heart Failure: The SCAN-MP Study. CJC Open. 2023 Apr; 5(4):292-302. PMID: 37124967; PMCID: PMC10140745; DOI: 10.1016/j.cjco.2022.12.011;

Ruberg FL, Baggish AL, Hays AG, Jerosch-Herold M, Kim J, Ordovas KG, Reddy G, Shenoy C, Weinsaft JW, Woodard PK. Utilization of cardiovascular magnetic resonance (CMR) imaging for resumption of athletic activities following COVID-19 infection: an expert consensus document on behalf of the American Heart Association Council on Cardiovascular Radiology and Intervention (CVRI) Leadership and endorsed by the Society for Cardiovascular Magnetic Resonance (SCMR). J Cardiovasc Magn Reson. 2022 Dec 21; 24(1):73. PMID: 36539786; PMCID: PMC9767806; DOI: 10.1186/s12968-022-00907-8;

Ruberg FL, Baggish AL, Hays AG, Jerosch-Herold M, Kim J, Ordovas KG, Reddy G, Shenoy C, Weinsaft JW, Woodard PK. Utilization of Cardiovascular Magnetic Resonance Imaging for Resumption of Athletic Activities Following COVID-19 Infection: An Expert Consensus Document on Behalf of the American Heart Association Council on Cardiovascular Radiology and Intervention Leadership and Endorsed by the Society for Cardiovascular Magnetic Resonance. Circ Cardiovasc Imaging. 2023 Jan; 16(1):e014106. PMID: 36541203; PMCID: PMC9848221; DOI: 10.1161/CIRCIMAGING.122.014106;

Rowin EJ, Ruberg FL, Das G, Higgins D, Lipe WC, Bokhari N, Dehn M, Maron BJ, Maron MS. Identification of Transthyretin Cardiac Amyloidosis Among Patients Previously Diagnosed With Hypertrophic Cardiomyopathy. Circ Cardiovasc Imaging. 2022 Dec; 15(12):e014938. PMID: 36448453; DOI: 10.1161/CIRCIMAGING.122.014938;

Cuddy SA, Datar Y, Ovsak G, Saith S, Murphy SP, Bay CP, Haddad M, Lilleness B, Muralidhar V, Pipilas A, Vuong J, Guardino E, Maurer MS, Ruberg FL, Falk RH, Dorbala S. Optimal Echocardiographic Parameters to Improve the Diagnostic Yield of Tc-99m-Bone Avid Tracer Cardiac Scintigraphy for Transthyretin Cardiac Amyloidosis. Circ Cardiovasc Imaging. 2022 Nov; 15(11):e014645.View Related Profiles.

Pipilas, Alexandra
Lilleness, Brian
Ruberg, Frederick
Datar, Yesh

PMID: 36378779; PMCID: PMC9667717; DOI: 10.1161/CIRCIMAGING.122.014645;

Minnema MC, Dispenzieri A, Merlini G, Comenzo RL, Kastritis E, Wechalekar AD, Grogan M, Witteles R, Ruberg FL, Maurer MS, Tran N, Qin X, Vasey SY, Weiss BM, Vermeulen J, Jaccard A. Outcomes by Cardiac Stage in Patients With Newly Diagnosed AL Amyloidosis: Phase 3 ANDROMEDA Trial. JACC CardioOncol. 2022 Nov; 4(4):474-487. PMID: 36444227; PMCID: PMC9700253; DOI: 10.1016/j.jaccao.2022.08.011;

Alreshq R, Cozzolino M, Lilleness B, Pipilas A, Mendelson L, Joshi T, Muralidhar V, Guardino E, Berk JL, Siddiqi OK, Gopal DM, Sanchorawala V, Ruberg FL. Light Chain Testing Abnormalities Among Patients With Transthyretin Amyloid Cardiomyopathy Referred for Technetium-99m Pyrophosphate Imaging. Am J Cardiol. 2022 Oct 15; 181:105-112.View Related Profiles.

Pipilas, Alexandra
Lilleness, Brian
Gopal, Deepa
Ruberg, Frederick
Berk, John
Mendelson, Lisa
Siddiqi, Omar
Joshi, Tracy
Sanchorawala, Vaishali

PMID: 36028388; PMCID: PMC9675982; DOI: 10.1016/j.amjcard.2022.06.064;

Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923. PMID: 35995766; PMCID: PMC9395431; DOI: 10.1038/s41467-022-32275-3;

Schwartz B, Schou M, Ruberg FL, Rucker D, Choi J, Siddiqi O, Monahan K, Køber L, Gislason G, Torp-Pedersen C, Andersson C. Cardiovascular Morbidity in Monoclonal Gammopathy of Undetermined Significance: A Danish Nationwide Study. JACC CardioOncol. 2022 Sep; 4(3):313-322.View Related Profiles.

Schwartz, Brian
Ruberg, Frederick
Monahan, Kevin
Siddiqi, Omar

PMID: 36213365; PMCID: PMC9537076; DOI: 10.1016/j.jaccao.2022.05.009;

Gustine JN, Staron A, Szalat RE, Mendelson LM, Joshi T, Ruberg FL, Siddiqi O, Gopal DM, Edwards CV, Havasi A, Kaku M, Lau KHV, Berk JL, Sloan JM, Sanchorawala V. Predictors of hematologic response and survival with stem cell transplantation in AL amyloidosis: A 25-year longitudinal study. Am J Hematol. 2022 Sep; 97(9):1189-1199.View Related Profiles.

Staron, Andrew
Edwards, Camille
Gopal, Deepa
Ruberg, Frederick
Sloan, J.
Berk, John
Lau, K.H. Vincent
Mendelson, Lisa
Kaku, Michelle
Siddiqi, Omar
Szalat, Raphael
Joshi, Tracy
Sanchorawala, Vaishali

PMID: 35731907

Poterucha TJ, Kurian D, Raiszadeh F, Teruya S, Elias P, Kogan R, Chiuzan C, Einstein AJ, Ruberg FL, Maurer MS. Relation of Body Mass Index to Transthyretin Cardiac Amyloidosis Particularly in Black and Hispanic Patients (from the SCAN-MP Study). Am J Cardiol. 2022 Aug 15; 177:116-120. PMID: 35705430

Siddiqi OK, Mints YY, Berk JL, Connors L, Doros G, Gopal DM, Kataria S, Lohrmann G, Pipilas AR, Ruberg FL. Diflunisal treatment is associated with improved survival for patients with early stage wild-type transthyretin (ATTR) amyloid cardiomyopathy: the Boston University Amyloidosis Center experience. Amyloid. 2022 Jun; 29(2):71-78.View Related Profiles.

Pipilas, Alexandra
Gopal, Deepa
Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Siddiqi, Omar

PMID: 35083944; PMCID: PMC9258521; DOI: 10.1080/13506129.2021.2000388;

Oster ME, Shay DK, Su JR, Gee J, Creech CB, Broder KR, Edwards K, Soslow JH, Dendy JM, Schlaudecker E, Lang SM, Barnett ED, Ruberg FL, Smith MJ, Campbell MJ, Lopes RD, Sperling LS, Baumblatt JA, Thompson DL, Marquez PL, Strid P, Woo J, Pugsley R, Reagan-Steiner S, DeStefano F, Shimabukuro TT. Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021. JAMA. 2022 01 25; 327(4):331-340.View Related Profiles.

Barnett, Elizabeth
Ruberg, Frederick

PMID: 35076665; PMCID: PMC8790664; DOI: 10.1001/jama.2021.24110;

Cuddy SAM, Jerosch-Herold M, Falk RH, Kijewski MF, Singh V, Ruberg FL, Sanchorawala V, Landau H, Maurer MS, Yee AJ, Bianchi G, Di Carli MF, Liao R, Kwong RY, Dorbala S. Myocardial Composition in Light-Chain Cardiac Amyloidosis More Than 1 Year After Successful Therapy. JACC Cardiovasc Imaging. 2022 Apr; 15(4):594-603.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 34922860; PMCID: PMC8995332; DOI: 10.1016/j.jcmg.2021.09.032;

Ruberg FL. Phenotype Mapping in Cardiac Amyloidosis. J Am Coll Cardiol. 2021 11 30; 78(22):2193-2195. PMID: 34823662

Alreshq R, Tugal D, Siddiqi O, Ruberg F. Conduction abnormalities and role of cardiac pacing in cardiac amyloidosis: A systematic review. Pacing Clin Electrophysiol. 2021 Dec; 44(12):2092-2099.View Related Profiles.

Tugal, Derin
Ruberg, Frederick
Siddiqi, Omar

PMID: 34632598

Maurer MS, Ruberg FL. Cardiac Scintigraphy and Screening for Transthyretin Cardiac Amyloidosis: Caveat Emptor. Circulation. 2021 09 28; 144(13):1005-1007. PMID: 34570590; PMCID: PMC8483571; DOI: 10.1161/CIRCULATIONAHA.121.055517;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. J Nucl Cardiol. 2021 Aug; 28(4):1763-1767. PMID: 34279803

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. J Nucl Cardiol. 2021 Aug; 28(4):1761-1762. PMID: 34259978

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. J Card Fail. 2022 Jul; 28(7):e1-e4. PMID: 34217819

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. J Nucl Cardiol. 2021 Aug; 28(4):1769-1774. PMID: 34196911

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Circ Cardiovasc Imaging. 2021 07; 14(7):e000029. PMID: 34196223

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Circ Cardiovasc Imaging. 2021 07; 14(7):e000030. PMID: 34196222

Patel RK, Fontana M, Ruberg FL. Cardiac Amyloidosis: Multimodal Imaging of Disease Activity and Response to Treatment. Circ Cardiovasc Imaging. 2021 06; 14(6):e009025. PMID: 34129344; PMCID: PMC8210461; DOI: 10.1161/CIRCIMAGING.121.009025;

Poterucha TJ, Elias P, Ruberg FL, DeLuca A, Kinkhabwala M, Johnson LL, Griffin JM, Pandey S, Einstein AJ, Maurer MS. False Positive 99mTc-Pyrophosphate Scanning Leading to Inappropriate Tafamidis Prescriptions. JACC Cardiovasc Imaging. 2021 10; 14(10):2042-2044.View Related Profiles.

Ruberg, Frederick
Pandey, Shivda

PMID: 34023264

Brannagan TH, Auer-Grumbach M, Berk JL, Briani C, Bril V, Coelho T, Damy T, Dispenzieri A, Drachman BM, Fine N, Gaggin HK, Gertz M, Gillmore JD, Gonzalez E, Hanna M, Hurwitz DR, Khella SL, Maurer MS, Nativi-Nicolau J, Olugemo K, Quintana LF, Rosen AM, Schmidt HH, Shehata J, Waddington-Cruz M, Whelan C, Ruberg FL. ATTR amyloidosis during the COVID-19 pandemic: insights from a global medical roundtable. Orphanet J Rare Dis. 2021 05 06; 16(1):204.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 33957949; PMCID: PMC8100737; DOI: 10.1186/s13023-021-01834-0;

Alreshq R, Ruberg FL. Clinical approach to genetic testing in amyloid cardiomyopathy: from mechanism to effective therapies. Curr Opin Cardiol. 2021 05 01; 36(3):309-317. PMID: 33605615; PMCID: PMC8221237; DOI: 10.1097/HCO.0000000000000841;

Lohrmann G, Patel MA, Brauneis D, Sanchorawala V, Sarosiek S, Vellanki N, Siddiqi OK, Ruberg FL, Gopal DM. Left Atrial Mechanics Associates With Paroxysmal Atrial Fibrillation in Light-Chain Amyloidosis Following Stem Cell Transplantation. JACC CardioOncol. 2020 Dec; 2(5):721-731.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Siddiqi, Omar
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 33511355; PMCID: PMC7839967; DOI: 10.1016/j.jaccao.2020.10.010;

Ruberg FL, Siddiqi OK. In Search of the Holy Grail: Evidence of Amyloid Fibril Regression in ATTR Cardiac Amyloidosis. JACC Cardiovasc Imaging. 2021 01; 14(1):200-202.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 33129738; PMCID: PMC8543316; DOI: 10.1016/j.jcmg.2020.08.021;

Poterucha TJ, Elias P, Ruberg FL, DeLuca A, Kinkhabwala M, Johnson LL, Maurer MS, Einstein AJ. The importance of SPECT cardiac reconstruction for accurate 99mTc-pyrophosphate interpretation in TTR amyloidosis. J Nucl Cardiol. 2022 Jun; 29(3):1478-1480. PMID: 33118142; DOI: 10.1007/s12350-020-02409-5;

Gertz M, Adams D, Ando Y, Beirão JM, Bokhari S, Coelho T, Comenzo RL, Damy T, Dorbala S, Drachman BM, Fontana M, Gillmore JD, Grogan M, Hawkins PN, Lousada I, Kristen AV, Ruberg FL, Suhr OB, Maurer MS, Nativi-Nicolau J, Quarta CC, Rapezzi C, Witteles R, Merlini G. Avoiding misdiagnosis: expert consensus recommendations for the suspicion and diagnosis of transthyretin amyloidosis for the general practitioner. BMC Fam Pract. 2020 09 23; 21(1):198. PMID: 32967612; PMCID: PMC7513485; DOI: 10.1186/s12875-020-01252-4;

Hanna M, Ruberg FL, Maurer MS, Dispenzieri A, Dorbala S, Falk RH, Hoffman J, Jaber W, Soman P, Witteles RM, Grogan M. Cardiac Scintigraphy With Technetium-99m-Labeled Bone-Seeking Tracers for Suspected Amyloidosis: JACC Review Topic of the Week. J Am Coll Cardiol. 2020 06 09; 75(22):2851-2862. PMID: 32498813; DOI: 10.1016/j.jacc.2020.04.022;

Kittleson MM, Maurer MS, Ambardekar AV, Bullock-Palmer RP, Chang PP, Eisen HJ, Nair AP, Nativi-Nicolau J, Ruberg FL. Cardiac Amyloidosis: Evolving Diagnosis and Management: A Scientific Statement From the American Heart Association. Circulation. 2020 07 07; 142(1):e7-e22. PMID: 32476490; DOI: 10.1161/CIR.0000000000000792;

Cuddy SAM, Bravo PE, Falk RH, El-Sady S, Kijewski MF, Park MA, Ruberg FL, Sanchorawala V, Landau H, Yee AJ, Bianchi G, Di Carli MF, Cheng SC, Jerosch-Herold M, Kwong RY, Liao R, Dorbala S. Improved Quantification of Cardiac Amyloid Burden in Systemic Light Chain Amyloidosis: Redefining Early Disease? JACC Cardiovasc Imaging. 2020 06; 13(6):1325-1336.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 32417333; PMCID: PMC8218539; DOI: 10.1016/j.jcmg.2020.02.025;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. J Nucl Cardiol. 2020 04; 27(2):659-673. PMID: 31468377

Ruberg FL, Siddiqi OK. Hepatocyte Growth Factor and Cardiac Amyloidosis. JACC CardioOncol. 2020 Mar; 2(1):67-69.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 32647833; PMCID: PMC7347296; DOI: 10.1016/j.jaccao.2020.02.004;

Khor YM, Cuddy S, Harms HJ, Kijewski MF, Park MA, Robertson M, Hyun H, Di Carli MF, Bianchi G, Landau H, Yee A, Sanchorawala V, Ruberg FL, Liao R, Berk J, Falk RH, Dorbala S. Quantitative [18F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis. Eur J Nucl Med Mol Imaging. 2020 07; 47(8):1998-2009.View Related Profiles.

Ruberg, Frederick
Berk, John
Sanchorawala, Vaishali

PMID: 31807884; PMCID: PMC8202062; DOI: 10.1007/s00259-019-04627-7;

Lohrmann G, Pipilas A, Mussinelli R, Gopal DM, Berk JL, Connors LH, Vellanki N, Hellawell J, Siddiqi OK, Fox J, Maurer MS, Ruberg FL. Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis. J Card Fail. 2020 Sep; 26(9):753-759.View Related Profiles.

Pipilas, Alexandra
Gopal, Deepa
Ruberg, Frederick
Berk, John
Connors, Lawreen
Siddiqi, Omar

PMID: 31805416; PMCID: PMC7758872; DOI: 10.1016/j.cardfail.2019.11.024;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. J Nucl Cardiol. 2019 12; 26(6):2065-2123. PMID: 31468376

Gopal DM, Ruberg FL, Siddiqi OK. Impact of Genetic Testing in Transthyretin (ATTR) Cardiac Amyloidosis. Curr Heart Fail Rep. 2019 10; 16(5):180-188.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Siddiqi, Omar

PMID: 31520266

Lilleness B, Doros G, Ruberg FL, Sanchorawala V. Establishment of brain natriuretic peptide - based criteria for evaluating cardiac response to treatment in light chain (AL) amyloidosis. Br J Haematol. 2020 02; 188(3):424-427.View Related Profiles.

Lilleness, Brian
Ruberg, Frederick
Doros, Gheorghe
Sanchorawala, Vaishali

PMID: 31515797

Maurer MS, Bokhari S, Damy T, Dorbala S, Drachman BM, Fontana M, Grogan M, Kristen AV, Lousada I, Nativi-Nicolau J, Cristina Quarta C, Rapezzi C, Ruberg FL, Witteles R, Merlini G. Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis. Circ Heart Fail. 2019 09; 12(9):e006075. PMID: 31480867; PMCID: PMC6736650; DOI: 10.1161/CIRCHEARTFAILURE.119.006075;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. J Card Fail. 2019 Nov; 25(11):854-865. PMID: 31473267; DOI: 10.1016/j.cardfail.2019.08.002;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. J Card Fail. 2019 Nov; 25(11):e1-e39. PMID: 31473268; DOI: 10.1016/j.cardfail.2019.08.001;

Staron A, Connors LH, Ruberg FL, Mendelson LM, Sanchorawala V. A new era of amyloidosis: the trends at a major US referral centre. Amyloid. 2019 Dec; 26(4):192-196.View Related Profiles.

Staron, Andrew
Ruberg, Frederick
Connors, Lawreen
Mendelson, Lisa
Sanchorawala, Vaishali

PMID: 31306033

Ruberg FL, Grogan M, Hanna M, Kelly JW, Maurer MS. Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 06 11; 73(22):2872-2891. PMID: 31171094; PMCID: PMC6724183; DOI: 10.1016/j.jacc.2019.04.003;

Ehman EC, El-Sady MS, Kijewski MF, Khor YM, Jacob S, Ruberg FL, Sanchorawala V, Landau H, Yee AJ, Bianchi G, Di Carli MF, Falk RH, Hyun H, Dorbala S. Early Detection of Multiorgan Light-Chain Amyloidosis by Whole-Body 18F-Florbetapir PET/CT. J Nucl Med. 2019 09; 60(9):1234-1239.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 30954943; PMCID: PMC6735282; DOI: 10.2967/jnumed.118.221770;

Maurer MS, Ruberg FL. Early Diagnosis of Cardiac Amyloidosis by Carpal Tunnel Surgery: Is it All in the Wrist? J Am Coll Cardiol. 2018 10 23; 72(17):2051-2053. PMID: 30336829

Lilleness B, Ruberg FL, Mussinelli R, Doros G, Sanchorawala V. Development and validation of a survival staging system incorporating BNP in patients with light chain amyloidosis. Blood. 2019 01 17; 133(3):215-223.View Related Profiles.

Lilleness, Brian
Ruberg, Frederick
Doros, Gheorghe
Sanchorawala, Vaishali

PMID: 30333122

Mints YY, Doros G, Berk JL, Connors LH, Ruberg FL. Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience. ESC Heart Fail. 2018 10; 5(5):772-779.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Mints, Yuliya

PMID: 29916559; PMCID: PMC6165925; DOI: 10.1002/ehf2.12308;

Siddiqi OK, Sanchorawala V, Ruberg FL. Echocardiography and Survival in Light Chain Cardiac Amyloidosis: Back to Basics. Circ Cardiovasc Imaging. 2018 05; 11(5):e007826.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar
Sanchorawala, Vaishali

PMID: 29752394

Martinez-Naharro A, Kotecha T, Norrington K, Boldrini M, Rezk T, Quarta C, Treibel TA, Whelan CJ, Knight DS, Kellman P, Ruberg FL, Gillmore JD, Moon JC, Hawkins PN, Fontana M. Native T1 and Extracellular Volume in Transthyretin Amyloidosis. JACC Cardiovasc Imaging. 2019 05; 12(5):810-819. PMID: 29550324

Jhaveri T, Sarosiek S, Ruberg FL, Siddiqi O, Berk JL, Sanchorawala V. Once AL amyloidosis: not always AL amyloidosis. Amyloid. 2018 Jun; 25(2):139-140.View Related Profiles.

Ruberg, Frederick
Berk, John
Siddiqi, Omar
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 29516761

Phull P, Sanchorawala V, Connors LH, Doros G, Ruberg FL, Berk JL, Sarosiek S. Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR). Amyloid. 2018 Mar; 25(1):62-67.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Phull, Pooja
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 29424556; PMCID: PMC6157907; DOI: 10.1080/13506129.2018.1436048;

Hanson JLS, Arvanitis M, Koch CM, Berk JL, Ruberg FL, Prokaeva T, Connors LH. Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin. Circ Heart Fail. 2018 02; 11(2):e004000.View Related Profiles.

Koch, Clarissa
Ruberg, Frederick
Berk, John
Connors, Lawreen
Prokaeva, Tatiana

PMID: 29449366; PMCID: PMC5819619; DOI: 10.1161/CIRCHEARTFAILURE.117.004000;

Maurer MS, Ruberg FL, Weinsaft JW. More Than Meets the Eye: Time for a New Imaging Paradigm to Test for Cardiac Amyloidosis. J Card Fail. 2018 02; 24(2):87-89. PMID: 29305971

Arvanitis M, Chan GG, Jacobson DR, Berk JL, Connors LH, Ruberg FL. Prevalence of mutant ATTR cardiac amyloidosis in elderly African Americans with heart failure. Amyloid. 2017 12; 24(4):253-255.View Related Profiles.

Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen

PMID: 29052438; PMCID: PMC5894279; DOI: 10.1080/13506129.2017.1391086;

Salinaro F, Meier-Ewert HK, Miller EJ, Pandey S, Sanchorawala V, Berk JL, Seldin DC, Ruberg FL. Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis. Eur Heart J Cardiovasc Imaging. 2017 Sep 01; 18(9):1057-1064.View Related Profiles.

Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Pandey, Shivda
Sanchorawala, Vaishali

PMID: 27965280; DOI: 10.1093/ehjci/jew298;

Arun M, Brauneis D, Doros G, Shelton AC, Sloan JM, Quillen K, Ruberg FL, Sanchorawala V, Varga C. The incidence of atrial fibrillation among patients with AL amyloidosis undergoing high-dose melphalan and stem cell transplantation: experience at a single institution. Bone Marrow Transplant. 2017 09; 52(9):1349-1351.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Sloan, J.
Quillen, Karen
Sanchorawala, Vaishali

PMID: 28737773

Siddiqi OK, Ruberg FL. Cardiac amyloidosis: An update on pathophysiology, diagnosis, and treatment. Trends Cardiovasc Med. 2018 01; 28(1):10-21.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 28739313; PMCID: PMC5741539; DOI: 10.1016/j.tcm.2017.07.004;

Siddiqi OK, Ruberg FL. Challenging the myths of cardiac amyloidosis. Eur Heart J. 2017 06 21; 38(24):1909-1912.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 28444296; DOI: 10.1093/eurheartj/ehx210;

Ruberg FL. Cardiac Amyloidosis: A Zebra Hiding in Plain Sight? Circ Cardiovasc Imaging. 2017 03; 10(3):e006186. PMID: 28298289; DOI: 10.1161/CIRCIMAGING.117.006186;

Di Carli MF, Davidoff R, Beerbaum P, Dorbala S, Gillam LD, Hoffmann U, Raman SV, Ruberg FL. Editor's Note. Circ Cardiovasc Imaging. 2017 03; 10(3).View Related Profiles.

Ruberg, Frederick
Davidoff, Ravin

PMID: 28289023; DOI: 10.1161/CIRCIMAGING.117.006334;

Arvanitis M, Koch CM, Chan GG, Torres-Arancivia C, LaValley MP, Jacobson DR, Berk JL, Connors LH, Ruberg FL. Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model. JAMA Cardiol. 2017 03 01; 2(3):305-313.View Related Profiles.

Koch, Clarissa
Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen
LaValley, Michael

PMID: 28196196; PMCID: PMC5497744; DOI: 10.1001/jamacardio.2016.5864;

Maurer M, Lousada I, Hanna M, Ruberg F, Mohty D, Dispenzieri A, Liedtke M, Paulson I, Vest J, Grogan M. Recommendations from the Amyloidosis Research Consortium Educational Roundtable at the American College of Cardiology Annual Meeting, 1 April 2016. Amyloid. 2017 Mar; 24(sup1):165-166. PMID: 28434366; DOI: 10.1080/13506129.2017.1286582;

Arvanitis M, Simon S, Chan G, Fine D, Beardsley P, LaValley M, Jacobson D, Koch C, Berk JL, Connors LH, Ruberg FL. Retinol binding protein 4 (RBP4) concentration identifies V122I transthyretin cardiac amyloidosis. Amyloid. 2017 Mar; 24(sup1):120-121.View Related Profiles.

Koch, Clarissa
Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen
LaValley, Michael

PMID: 28434357; PMCID: PMC5497748; DOI: 10.1080/13506129.2017.1295371;

Buxbaum JN, Ruberg FL. Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans. Genet Med. 2017 Jul; 19(7):733-742. PMID: 28102864; PMCID: PMC5509498; DOI: 10.1038/gim.2016.200;

Ruberg FL, Fontana M, Gillmore JD. Should Histologic Determination of Amyloid Load Determine Management Decisions in Light-Chain Amyloidosis? J Am Coll Cardiol. 2016 12 06; 68(22):2493-2494. PMID: 27908360; DOI: 10.1016/j.jacc.2016.07.786;

Castano A, Haq M, Narotsky DL, Goldsmith J, Weinberg RL, Morgenstern R, Pozniakoff T, Ruberg FL, Miller EJ, Berk JL, Dispenzieri A, Grogan M, Johnson G, Bokhari S, Maurer MS. Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis. JAMA Cardiol. 2016 11 01; 1(8):880-889.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27557400; DOI: 10.1001/jamacardio.2016.2839;

Haq M, Pawar S, Berk JL, Miller EJ, Ruberg FL. Can 99mTc-Pyrophosphate Aid in Early Detection of Cardiac Involvement in Asymptomatic Variant TTR Amyloidosis? JACC Cardiovasc Imaging. 2017 06; 10(6):713-714.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27568122; PMCID: PMC5318295; DOI: 10.1016/j.jcmg.2016.06.003;

Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. J Nucl Cardiol. 2017 Apr; 24(2):413-424.View Related Profiles.

Ruberg, Frederick
Berman, Jeffrey
Govender, Praveen

PMID: 27457527; DOI: 10.1007/s12350-016-0490-7;

Gillmore JD, Maurer MS, Falk RH, Merlini G, Damy T, Dispenzieri A, Wechalekar AD, Berk JL, Quarta CC, Grogan M, Lachmann HJ, Bokhari S, Castano A, Dorbala S, Johnson GB, Glaudemans AW, Rezk T, Fontana M, Palladini G, Milani P, Guidalotti PL, Flatman K, Lane T, Vonberg FW, Whelan CJ, Moon JC, Ruberg FL, Miller EJ, Hutt DF, Hazenberg BP, Rapezzi C, Hawkins PN. Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis. Circulation. 2016 Jun 14; 133(24):2404-12.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27143678; DOI: 10.1161/CIRCULATIONAHA.116.021612;

Jefferson AL, Gifford KA, Acosta LM, Bell SP, Donahue MJ, Davis LT, Gottlieb J, Gupta DK, Hohman TJ, Lane EM, Libon DJ, Mendes LA, Niswender K, Pechman KR, Rane S, Ruberg FL, Su YR, Zetterberg H, Liu D. The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview. J Alzheimers Dis. 2016 03 08; 52(2):539-59.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 26967211; PMCID: PMC4866875; DOI: 10.3233/JAD-150914;

Connors LH, Sam F, Skinner M, Salinaro F, Sun F, Ruberg FL, Berk JL, Seldin DC. Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study. Circulation. 2016 Jan 19; 133(3):282-90.View Related Profiles.

Sun, Fangui
Sam, Flora
Ruberg, Frederick
Berk, John
Connors, Lawreen
Skinner, Martha

PMID: 26660282; PMCID: PMC4718760; DOI: 10.1161/CIRCULATIONAHA.115.018852;

Ruberg FL, Nezafat R. Cardiovascular Magnetic Resonance Visualization of Cardiac Amyloid Infiltration: Challenges and Opportunities. Circulation. 2015 Oct 20; 132(16):1525-7. PMID: 26362630; PMCID: PMC4725194; DOI: 10.1161/CIRCULATIONAHA.115.018832;

Hohman TJ, Samuels LR, Liu D, Gifford KA, Mukherjee S, Benson EM, Abel T, Ruberg FL, Jefferson AL. Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes. Neurobiol Aging. 2015 Sep; 36(9):2501-8.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 26119224; PMCID: PMC4523400; DOI: 10.1016/j.neurobiolaging.2015.05.021;

Ruberg FL, Berk JL, Semigan MJ. V122I transthyretin variant in elderly black Americans. N Engl J Med. 2015 Apr 30; 372(18):1768.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 25923563; DOI: 10.1056/NEJMc1503222#SA1;

Jefferson AL, Hohman TJ, Liu D, Haj-Hassan S, Gifford KA, Benson EM, Skinner JS, Lu Z, Sparling J, Sumner EC, Bell S, Ruberg FL. Adverse vascular risk is related to cognitive decline in older adults. J Alzheimers Dis. 2015; 44(4):1361-73.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 25471188; PMCID: PMC4336578; DOI: 10.3233/JAD-141812;

Ahmadian A, Brogan A, Berman J, Sverdlov AL, Mercier G, Mazzini M, Govender P, Ruberg FL, Miller EJ. Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis. J Nucl Cardiol. 2014 Oct; 21(5):925-39.View Related Profiles.

Sverdlov, Aaron
Miller, Edward
Ruberg, Frederick
Mercier, Gustavo
Berman, Jeffrey
Mazzini, Michael
Govender, Praveen

PMID: 24879453; DOI: 10.1007/s12350-014-9901-9;

Hua N, Chen Z, Phinikaridou A, Pham T, Qiao Y, LaValley MP, Bigornia SJ, Ruth MR, Apovian CM, Ruberg FL, Hamilton JA. The influence of pericardial fat upon left ventricular function in obese females: evidence of a site-specific effect. J Cardiovasc Magn Reson. 2014; 16:37.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Hamilton, James
Ruth, Megan
LaValley, Michael
Hua, Ning

PMID: 24884541; PMCID: PMC4046092; DOI: 10.1186/1532-429X-16-37;

Berman JS, Govender P, Ruberg FL, Mazzini M, Miller EJ. Scadding revisited: a proposed staging system for cardiac sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2014; 31(1):2-5.View Related Profiles.

Ruberg, Frederick
Berman, Jeffrey
Mazzini, Michael
Govender, Praveen

PMID: 24751447

Girnius S, Seldin DC, Meier-Ewert HK, Sloan JM, Quillen K, Ruberg FL, Berk JL, Doros G, Sanchorawala V. Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement. Bone Marrow Transplant. 2014 Mar; 49(3):434-9.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Sanchorawala, Vaishali

PMID: 24317129; DOI: 10.1038/bmt.2013.192;

Ruberg FL. T1 mapping in cardiac amyloidosis: can we get there from here? JACC Cardiovasc Imaging. 2013 Apr; 6(4):498-500. PMID: 23498671; DOI: 10.1016/j.jcmg.2013.01.007;

Ruberg FL, Miller EJ. Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up? Circ Cardiovasc Imaging. 2013 Mar 1; 6(2):162-4.View Related Profiles.

Miller, Edward
Ruberg, Frederick

PMID: 23512778; DOI: 10.1161/CIRCIMAGING.113.000178;

Tsai SB, Seldin DC, Quillen K, Berk JL, Ruberg FL, Meier-Ewert H, Sloan JM, Doros G, Finn KT, Skinner M, Sanchorawala V. High-dose melphalan and stem cell transplantation for patients with AL amyloidosis: trends in treatment-related mortality over the past 17 years at a single referral center. Blood. 2012 Nov 22; 120(22):4445-6.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Skinner, Martha
Sanchorawala, Vaishali

PMID: 23175664; DOI: 10.1182/blood-2012-09-457341;

Ruberg FL, Berk JL. Transthyretin (TTR) cardiac amyloidosis. Circulation. 2012 Sep 4; 126(10):1286-300.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 22949539; PMCID: PMC3501197; DOI: 10.1161/CIRCULATIONAHA.111.078915;

Ruberg FL, Maurer MS, Judge DP, Zeldenrust S, Skinner M, Kim AY, Falk RH, Cheung KN, Patel AR, Pano A, Packman J, Grogan DR. Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: the Transthyretin Amyloidosis Cardiac Study (TRACS). Am Heart J. 2012 Aug; 164(2):222-228.e1.View Related Profiles.

Ruberg, Frederick
Skinner, Martha

PMID: 22877808; DOI: 10.1016/j.ahj.2012.04.015;

Freeman B, Sloan JM, Seldin DC, Cowan AJ, Ruberg FL, Sanchorawala V. Multiple arterial and venous thromboembolic complications in AL amyloidosis and cardiac involvement: a case report and literature review. Amyloid. 2012 Sep; 19(3):156-60.View Related Profiles.

Seldin, David
Ruberg, Frederick
Sloan, J.
Sanchorawala, Vaishali

PMID: 22680044; DOI: 10.3109/13506129.2012.694825;

Meier-Ewert HK, Sanchorawala V, Berk JL, Ruberg FL. Cardiac amyloidosis: evolving approach to diagnosis and management. Curr Treat Options Cardiovasc Med. 2011 Dec; 13(6):528-42.View Related Profiles.

Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Sanchorawala, Vaishali

PMID: 21989745; DOI: 10.1007/s11936-011-0147-4;

Cibeira MT, Sanchorawala V, Seldin DC, Quillen K, Berk JL, Dember LM, Segal A, Ruberg F, Meier-Ewert H, Andrea NT, Sloan JM, Finn KT, Doros G, Blade J, Skinner M. Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients. Blood. 2011 Oct 20; 118(16):4346-52.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Dember, Laura
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21828140; PMCID: PMC3204906; DOI: 10.1182/blood-2011-01-330738;

Meier-Ewert HK, Sanchorawala V, Berk J, Finn KT, Skinner M, Seldin DC, Ruberg FL. Regression of cardiac wall thickness following chemotherapy and stem cell transplantation for light chain (AL) amyloidosis. Amyloid. 2011 Jun; 18 Suppl 1:130-1.View Related Profiles.

Seldin, David
Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21838460; DOI: 10.3109/13506129.2011.574354048;

Seldin DC, Andrea N, Berenbaum I, Berk JL, Connors L, Dember LM, Doros G, Fennessey S, Finn K, Girnius S, Lerner A, Libbey C, Meier-Ewert HK, O'Connell R, O'Hara C, Quillen K, Ruberg FL, Sam F, Segal A, Shelton A, Skinner M, Sloan JM, Wiesman JF, Sanchorawala V. High-dose melphalan and autologous stem cell transplantation for AL amyloidosis: recent trends in treatment-related mortality and 1-year survival at a single institution. Amyloid. 2011 Jun; 18 Suppl 1:127-9.View Related Profiles.

Lerner, Adam
O'Hara, Carl
Libbey, Caryn
Seldin, David
Sam, Flora
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Berenbaum, Isidore
Sloan, J.
Wiesman, Janice
Berk, John
Quillen, Karen
Dember, Laura
Connors, Lawreen
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21838459; PMCID: PMC5601311; DOI: 10.3109/13506129.2011.574354047;

Tsai SB, Seldin DC, Wu H, O'Hara C, Ruberg FL, Sanchorawala V. Myocardial infarction with "clean coronaries" caused by amyloid light-chain AL amyloidosis: a case report and literature review. Amyloid. 2011 Sep; 18(3):160-4.View Related Profiles.

O'Hara, Carl
Seldin, David
Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 21504342; DOI: 10.3109/13506129.2011.571319;

Bhuiyan T, Helmke S, Patel AR, Ruberg FL, Packman J, Cheung K, Grogan D, Maurer MS. Pressure-volume relationships in patients with transthyretin (ATTR) cardiac amyloidosis secondary to V122I mutations and wild-type transthyretin: Transthyretin Cardiac Amyloid Study (TRACS). Circ Heart Fail. 2011 Mar; 4(2):121-8. PMID: 21191093; PMCID: PMC4939845; DOI: 10.1161/CIRCHEARTFAILURE.109.910455;

Ruberg FL. Paying at the pump: diet-induced accumulation of cardiac lipid and systolic dysfunction. Circ Cardiovasc Imaging. 2010 Nov; 3(6):635-7. PMID: 21081742; DOI: 10.1161/CIRCIMAGING.110.960476;

Amsterdam EA, Kirk JD, Bluemke DA, Diercks D, Farkouh ME, Garvey JL, Kontos MC, McCord J, Miller TD, Morise A, Newby LK, Ruberg FL, Scordo KA, Thompson PD. Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association. Circulation. 2010 Oct 26; 122(17):1756-76. PMID: 20660809; PMCID: PMC3044644; DOI: 10.1161/CIR.0b013e3181ec61df;

Phinikaridou A, Ruberg FL, Hallock KJ, Qiao Y, Hua N, Viereck J, Hamilton JA. In vivo detection of vulnerable atherosclerotic plaque by MRI in a rabbit model. Circ Cardiovasc Imaging. 2010 May; 3(3):323-32.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James
Hallock, Kevin
Hua, Ning

PMID: 20194634; DOI: 10.1161/CIRCIMAGING.109.918524;

Ruberg FL, Chen Z, Hua N, Bigornia S, Guo Z, Hallock K, Jara H, LaValley M, Phinikaridou A, Qiao Y, Viereck J, Apovian CM, Hamilton JA. The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. Obesity (Silver Spring). 2010 Jun; 18(6):1116-21.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Jara, Hernan
Hamilton, James
Hallock, Kevin
LaValley, Michael
Hua, Ning
Chen, Zhongjing

PMID: 19875992; PMCID: PMC3264050; DOI: 10.1038/oby.2009.363;

Ruberg FL, Judge DP, Maurer MS. Familial amyloid cardiomyopathy due to TTR mutations: an underdiagnosed cause of restrictive cardiomyopathy [corrected]. J Card Fail. 2009 Jun; 15(5):464. PMID: 19477408; DOI: 10.1016/j.cardfail.2009.04.003;

Ruberg FL, Appelbaum E, Davidoff R, Ozonoff A, Kissinger KV, Harrigan C, Skinner M, Manning WJ. Diagnostic and prognostic utility of cardiovascular magnetic resonance imaging in light-chain cardiac amyloidosis. Am J Cardiol. 2009 Feb 15; 103(4):544-9.View Related Profiles.

Ozonoff, Alexander
Ruberg, Frederick
Skinner, Martha
Davidoff, Ravin

PMID: 19195518; PMCID: PMC2680134; DOI: 10.1016/j.amjcard.2008.09.105;

Goyal SK, Punnam SR, Verma G, Ruberg FL. Persistent left superior vena cava: a case report and review of literature. Cardiovasc Ultrasound. 2008; 6:50. PMID: 18847480; PMCID: PMC2576163; DOI: 10.1186/1476-7120-6-50;

Rosito GA, Massaro JM, Hoffmann U, Ruberg FL, Mahabadi AA, Vasan RS, O'Donnell CJ, Fox CS. Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study. Circulation. 2008 Feb 5; 117(5):605-13.View Related Profiles.

O'Donnell, Christopher
Ruberg, Frederick
Massaro, Joseph
Ramachandran, Vasan

PMID: 18212276; DOI: 10.1161/CIRCULATIONAHA.107.743062;

Dinwoodey DL, Skinner M, Maron MS, Davidoff R, Ruberg FL. Light-chain amyloidosis with echocardiographic features of hypertrophic cardiomyopathy. Am J Cardiol. 2008 Mar 1; 101(5):674-6.View Related Profiles.

Ruberg, Frederick
Skinner, Martha
Davidoff, Ravin

PMID: 18308019; DOI: 10.1016/j.amjcard.2007.10.031;

Ruberg FL. Myocardial lipid accumulation in the diabetic heart. Circulation. 2007 Sep 4; 116(10):1110-2. PMID: 17768302

Qiao Y, Ronen I, Viereck J, Ruberg FL, Hamilton JA. Identification of atherosclerotic lipid deposits by diffusion-weighted imaging. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1440-6.View Related Profiles.

Ruberg, Frederick
Hamilton, James

PMID: 17379838; PMCID: PMC2910580; DOI: 10.1161/ATVBAHA.107.141028;

Ruberg FL, McDonnell ME, Trabb J, Shemin RJ, Hoyt RF, Braverman LE, Balady GJ. An intracardiac accessory thyroid gland. Am J Cardiol. 2006 Mar 15; 97(6):926-8.View Related Profiles.

Ruberg, Frederick
Balady, Gary
Braverman, Lewis
McDonnell, Marie
Hoyt, Richard

PMID: 16516604

Ruberg FL, Loscalzo J. Normal Mechanisms of Hemostasis. In: Loscalzo J, Dzau V, and Creager M, eds. Vascular Medicine, A Companion to Braunwald’s Heart Disease. Saunders/Elsevier. Philadelphia. 2006; 61-70.

Davidoff R, Ruberg FL. Newer cardiac imaging techniques: multidetector CT angiography. J Insur Med. 2006; 38(2):116-25.View Related Profiles.

Ruberg, Frederick
Davidoff, Ravin

PMID: 16845845

Ruberg FL, Viereck J, Phinikaridou A, Qiao Y, Loscalzo J, Hamilton JA. Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS. J Lipid Res. 2006 Feb; 47(2):310-7.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James

PMID: 16317172

Ruberg FL, Kissinger KV, Manning WJ. Images in cardiovascular medicine. Diaphragmatic motion during Cheyne-Stokes respiration by navigator magnetic resonance imaging. Circulation. 2005 Sep 6; 112(10):e132. PMID: 16145007

Viereck J, Ruberg FL, Qiao Y, Perez AS, Detwiller K, Johnstone M, Hamilton JA. MRI of atherothrombosis associated with plaque rupture. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):240-5.View Related Profiles.

Ruberg, Frederick
Hamilton, James
Johnstone, Michael

PMID: 15528478

Ruberg FL, Leopold JA, Loscalzo J. Atherothrombosis: plaque instability and thrombogenesis. Prog Cardiovasc Dis. 2002 Mar-Apr; 44(5):381-94. PMID: 12024336

Ruberg FL, Loscalzo J. Prothrombotic determinants of coronary atherothrombosis. Vasc Med. 2002; 7(4):289-99. PMID: 12710845

O'Brien CD, Ji G, Wang YX, Sun J, Krymskaya VP, Ruberg FL, Kotlikoff MI, Albelda SM. PECAM-1 (CD31) engagement activates a phosphoinositide-independent, nonspecific cation channel in endothelial cells. FASEB J. 2001 May; 15(7):1257-60. PMID: 11344106

Gurubhagavatula I, Amrani Y, Pratico D, Ruberg FL, Albelda SM, Panettieri RA. Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release. J Clin Invest. 1998 Jan 1; 101(1):212-22. PMID: 9421484; PMCID: PMC508558

Ruberg FL, Skene DJ, Hanifin JP, Rollag MD, English J, Arendt J, Brainard GC. Melatonin regulation in humans with color vision deficiencies. J Clin Endocrinol Metab. 1996 Aug; 81(8):2980-5. PMID: 8768862

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 161 publications over 26 distinct years, with a maximum of 15 publications in 2023 and 2024 and 2025

Bar chart showing 161 publications over 26 distinct years, with a maximum of 15 publications in 2023 and 2024 and 2025

Year	Publications
1996	1
1998	1
2001	1
2002	2
2004	1
2005	2
2006	3
2007	3
2008	3
2009	2
2010	4
2011	5
2012	4
2013	3
2014	3
2015	5
2016	6
2017	11
2018	9
2019	11
2020	9
2021	14
2022	13
2023	15
2024	15
2025	15

Media Mentions
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In addition to these self-described keywords below, a list of MeSH based concepts is available here.

amyloidosis
Cardiac-Gated Imaging Techniques
echocardiography
MRI

Dr. Ruberg is Chief, Section of Cardiovascular Medicine and Workforce Development Co-Lead, BU Clinical and Translational Science Institute (CTSI). He is the Thomas J. Ryan Professor of Cardiovascular Medicine and Professor of Radiology at Boston University Chobanian & Avedisian School of Medicine. An active clinical cardiologist and clinical investigator, Dr. Ruberg’s commitment to interdisciplinary research and team science is exemplified by his various responsibilities at BUMC. His clinical interest is in infiltrative cardiomyopathy and he is a participating clinician and researcher in the multi-disciplinary BU/BMC Amyloidosis Center. He is an internationally recognized expert in cardiac amyloidosis. His clinical and research expertise is in the field of cardiac imaging with interest in refining quantitative techniques for application in the clinical care of infiltrative cardiomyopathies. His research has been funded by the American Heart Association (AHA), foundations, industry, and NIH. Research collaboration include investigators in Boston, elsewhere in the US, and world-wide. Dr. Ruberg has servs as Senior Associate Editor of Circulation: Cardiovascular Imaging. He is a fellow of the American College of Cardiology and the American Heart Association. Dr. Ruberg is an active mentor of Internal Medicine residents and Cardiovascular Medicine fellows, having been awarding the 2017 Research Mentor of the year award from the IM residency and the 2022 Citizenship Award from the Department of Medicine. He serves on the Executive Committee of the NIH/NHLBI R38 award designed to facilitate research experiences for MD-trained IM residents.

Available to Mentor as: (Review Mentor Role Definitions):