Frederick L. Ruberg, MD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, University of Pennsylvania School of Medicine

Dr. Ruberg's clinical and research expertise is in the field of cardiac imaging including echocardiography and cardiovascular magnetic resonance imaging (CMR). Dr. Ruberg applies imaging in research designed to facilitate improved diagnosis and management of the infiltrative cardiomyopathy cardiac amyloidosis.

Associate Professor
Boston University School of Medicine

Program Director
Boston University School of Medicine
Clinical and Translational Science Institute
Pilot Translational & Clinical Studies Program

Active Staff Privileges
Boston Medical Center

Molecular Imaging of Primary Amyloid Cardiomyopathy
04/01/2017 - 03/31/2019 (PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI

Longitudinal strain in ATTR cardiac amyloidosis
09/25/2017 - 09/25/2020 (PI)
Eidos Therapeutics

(Prenotification) Scan-MP (Screening fro cardiac amyloidosis with nuclear imaging in minority…
12/01/2018 - 11/30/2019 (PI)
Trustees of Columbia University NIH-NHLBI

Serum Biomarker identification of cardiac amyloidosis in elderly African Americans
04/15/2015 - 03/31/2017 (PI)

Cardiac Function as a mechanism for maladaptive brain aging (Supplement)
09/01/2015 - 04/30/2016 (PI)
Vanderbilt University Medical Center NIH-NIA

Cardiac Function as a Mechanism for Maladaptive Brain Aging
07/01/2014 - 04/30/2016 (PI)
Vanderbilt University Medical Center NIH-NIA

Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE)
02/01/2011 - 04/30/2015 (PI)
Duke University NIH-NHLBI

Oxidant stress, Matrix remodeling and stem cell transplant in cardiac amyloidosis
01/01/2010 - 12/31/2014 (PI)
American Heart Assoc

Ventricular Remodeling in Cardiac Amyloidosis Following Stem Cell Transplantation: A Cardiovascular
12/01/2009 - 06/30/2014 (PI)
Amyloidosis Foundation

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Ruberg FL, Grogan M, Hanna M, Kelly JW, Maurer MS. Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 Jun 11; 73(22):2872-2891. PMID: 31171094.
  2. Ehman EC, El-Sady MS, Kijewski MF, Khor YM, Jacob S, Ruberg FL, Sanchorawala V, Landau H, Yee AJ, Bianchi G, Di Carli MF, Falk RH, Hyun H, Dorbala S. Early Detection of Multiorgan Light Chain (AL) Amyloidosis by Whole Body 18F-florbetapir PET/CT. J Nucl Med. 2019 Apr 06.View Related Profiles. PMID: 30954943; DOI: 10.2967/jnumed.118.221770;.
  3. Maurer MS, Ruberg FL. Early Diagnosis of Cardiac Amyloidosis by Carpal Tunnel Surgery: Is it All in the Wrist? J Am Coll Cardiol. 2018 Oct 23; 72(17):2051-2053. PMID: 30336829.
  4. Lilleness B, Ruberg FL, Mussinelli R, Doros G, Sanchorawala V. Development and validation of a survival staging system incorporating BNP in patients with light chain amyloidosis. Blood. 2019 Jan 17; 133(3):215-223.View Related Profiles. PMID: 30333122.
  5. Mints YY, Doros G, Berk JL, Connors LH, Ruberg FL. Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience. ESC Heart Fail. 2018 10; 5(5):772-779.View Related Profiles. PMID: 29916559.
  6. Siddiqi OK, Sanchorawala V, Ruberg FL. Echocardiography and Survival in Light Chain Cardiac Amyloidosis: Back to Basics. Circ Cardiovasc Imaging. 2018 May; 11(5):e007826.View Related Profiles. PMID: 29752394.
  7. Martinez-Naharro A, Kotecha T, Norrington K, Boldrini M, Rezk T, Quarta C, Treibel TA, Whelan CJ, Knight DS, Kellman P, Ruberg FL, Gillmore JD, Moon JC, Hawkins PN, Fontana M. Native T1 and Extracellular Volume in Transthyretin Amyloidosis. JACC Cardiovasc Imaging. 2019 May; 12(5):810-819. PMID: 29550324.
  8. Jhaveri T, Sarosiek S, Ruberg FL, Siddiqi O, Berk JL, Sanchorawala V. Once AL amyloidosis: not always AL amyloidosis. Amyloid. 2018 Jun; 25(2):139-140.View Related Profiles. PMID: 29516761.
  9. Phull P, Sanchorawala V, Connors LH, Doros G, Ruberg FL, Berk JL, Sarosiek S. Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR). Amyloid. 2018 Mar; 25(1):62-67.View Related Profiles. PMID: 29424556.
  10. Hanson JLS, Arvanitis M, Koch CM, Berk JL, Ruberg FL, Prokaeva T, Connors LH. Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin. Circ Heart Fail. 2018 02; 11(2):e004000.View Related Profiles. PMID: 29449366.
Showing 10 of 74 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 74 publications over 20 distinct years, with a maximum of 11 publications in 2017

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cardiac-Gated Imaging Techniques

Dr. Ruberg is the Director, Pilot Grants Program, BU CTSI and an Associate Professor of Medicine and Radiology at Boston University School of Medicine. Dr. Ruberg is also the Director of the Cardiovascular Medicine Fellowship Training Program. An active clinical cardiologist and investigator, Dr. Ruberg’s commitment to interdisciplinary research and team science is exemplified by his various responsibilities at BUMC. He is the Director of the Advanced Cardiac Imaging Program at Boston Medical Center – a clinical service involving clinicians and trainees in the Departments of Radiology and Medicine. His clinical interest is in infiltrative cardiomyopathy and he is a participating clinician and researcher in the multi-disciplinary BU Amyloidosis Center and Sarcoidosis Center. He is a nationally recognized expert in cardiac amyloidosis. His clinical and research expertise is in the field of cardiac imaging with interest in refining quantitative MR techniques for application in the clinical care of infiltrative cardiomyopathies. His research has been funded by the American Heart Association (AHA), Amyloidosis Foundation, and NIH. In addition to his own grant awards, Dr. Ruberg is also co-investigator on both BUMC and outside BMC collaborative projects, including the NIH-funded Vanderbilt Memory and Alzheimer’s Center. Dr. Ruberg is a peer reviewer for numerous journals including Circulation, Annals of Internal Medicine, Journal of the American College of Cardiology, and JACC: Cardiovascular Imaging. He has served as an NIH peer reviewer and is a member of the editorial board of Circulation: Cardiovascular Imaging. Dr. Ruberg is a fellow of the American College of Cardiology and the AHA. Dr. Ruberg is an active mentor of Internal Medicine residents and Cardiovascular Medicine fellows. Past projects have involved cardiac imaging and past mentees have reported finding at the major national Cardiology meetings and published reports in the peer reviewed literature.

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Diversity Mentor
  • Project Mentor
  • Research / Scholarly Mentor
  • Work / Life Integration Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

75 E. Newton St Collamore Building
Boston MA 02118
Google Map

Ruberg's Networks
Click the "See All" links for more information and interactive visualizations
Similar People
Same Department