Eric Burks, MD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology

MD, University of New Mexico School of Medicine
BS, New Mexico State University



Eric Burks, MD, studies screening-detected non-small cell lung cancer. Dr. Burks’ studies established the diagnostic criteria for an entity now known as pulmonary adenocarcinoma of low malignant potential (LMP) which has been internationally validated and shown to account for overdiagnosis in the National Lung Screening Trial (NLST). His work has further established angioinvasive lung adenocarcinoma as the most aggressive form of early-stage NSCLC. Patients with small (<2 cm) angioinvasive tumors benefit from surgical resection of the entire involved lung lobe whereas the remaining patients are adequately treated with parenchymal sparing approaches such as wedge resection. Dr. Burks is a provisional patent holder (BU-2023-026) for biomarkers associated with angioinvasive lung adenocarcinoma, a co-investigator on a U01, The Lung Pre-Cancer Atlas project, a site PI on two R01s and a co-PI on an American Society of Hematology grant. In addition, he directs hematopathology, the hematology laboratory, the immunohistochemistry and special procedures laboratory, including amyloid pathology, and the hemoglobin diagnostic reference laboratory at Boston Medical Center.

Member
Boston University
BU-BMC Cancer Center





Integrating imaging and biopsy-derived molecular markers for the pre-surgical detection of indolent and aggressive early stage lung adenocarcinoma
07/10/2023 - 06/30/2025 (Subcontract PI)
PI: Eric Burks, MD
Trustees of Boston University, BUMC NIH NCI
1R01CA275015-01A1


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Xu L, Kefella Y, Zhang Y, Conrad RD, Anderson KE, Krysan K, Liu G, Kane E, Pennycuick A, Merrick DT, Janes SM, Reid ME, Burks EJ, Billatos E, Mazzilli SA, Kolachalama VB, Beane JE. Attention-based deep learning for analysis of pathology images and gene expression data in lung squamous premalignant lesions. Genome Med. 2026 Apr 08. PMID: 41952176; DOI: 10.1186/s13073-026-01636-8;
     
  2. Ning B, Chiu DJ, Pfefferkorn RM, Cullinane E, Kefella Y, Kane E, Reyes-Ortiz V, Liu G, Zhang X, Liu H, Sultan L, Green E, Constant M, Spira AE, Campbell JD, Reid ME, Varelas X, Burks EJ, Lenburg ME, Mazzilli SA, Beane JE. Upregulation of an Epithelial miRNA Is Associated with Immune Evasion in Progressive Bronchial Premalignant Lesions. Cancer Immunol Res. 2026 Apr 02; 14(4):689-707.View Related Profiles. PMID: 41670462; DOI: 10.1158/2326-6066.CIR-25-0431;
     
  3. George T, Staron A, Burks EJ, Szalat RE, Sanchorawala V. Cyclin D1 immunostaining as a diagnostic surrogate for the t(11;14) translocation in AL amyloidosis. Br J Haematol. 2026 Mar 29. PMID: 41905782; DOI: 10.1111/bjh.70461;
     
  4. Steiner D, Sultan L, Sullivan T, Liu H, Xiao X, LeClerc A, Melvin S, Alekseyev YO, Liu G, Mazzilli SA, Zhang J, Suzuki K, Rieger-Christ K, Burks EJ, Beane J, Lenburg ME. Vascular invasion-associated gene expression is detectable in pre-surgical biopsies of stage I lung adenocarcinoma. Nat Commun. 2026 Mar 24; 17(1). PMID: 41876493; PMCID: PMC13013712; DOI: 10.1038/s41467-026-70600-2;
     
  5. Xi ZH, Koga Y, McDermott S, Kane EE, Pfefferkorn R, Billatos E, Hosking PR, Beane JE, Burks EJ, Mazzilli SA, Suzuki K, Campbell JD. Multimodal single-cell and spatial profiling reveals altered T cell-mediated immunity and B-cell follicular architecture in non-metastatic lymph nodes of patients with aggressive non-small cell lung cancer. medRxiv. 2026 Jan 18.View Related Profiles. PMID: 41646724; PMCID: PMC12870645; DOI: 10.64898/2026.01.12.25343268;
     
  6. Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Francis C, Elsadawi M, Wu Wong DJ, Kenney D, Douam F, Bosmann M, Whelan SA, Cabral H, Burks EJ, Zhao G, Kolachalama VB, Ravid K, Chitalia VC. Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2. Blood Vessel Thromb Hemost. 2026 Feb; 3(1):100128. PMID: 41743170; PMCID: PMC12930169; DOI: 10.1016/j.bvth.2025.100128;
     
  7. Zheng H., Yambayev I., Shevstov A., Burks E.J. AME Medical Journal. Narrative review of the pathologic assessment of immune response in lung cancer. 2026; 6:36. View Publication
  8. Burke NJ, Mendelson LM, Joshi T, Libbey C, Burks EJ, Prokaeva T, Spencer B, Zheng L, Doros G, Sanchorawala V, Staron A. Detection yield of surrogate tissue biopsies across amyloidosis classes: a large-scale analysis of 4,027 patients. Amyloid. 2025 Dec 29; 1-9.View Related Profiles. PMID: 41460224; DOI: 10.1080/13506129.2025.2606847;
     
  9. Zhou Y, Lu W, Burks E, Henderson JM, Andry C, Sanchorawala V, Sheikh Z, Prokaeva TB, Chen HA. Optimized methods for efficient application of immunogold electron microscopy to amyloid fibrils typing. Amyloid. 2026 Mar; 33(1):47-58.View Related Profiles. PMID: 41275507
     
  10. Anderson KE, Tran LM, Krysan K, Kefella Y, Yu L, Fishbein GA, Rodriguez E, Shabihkhani M, Stefanko DP, Green E, Liu G, Liu H, Zhang S, Kane E, Mehrad M, Spira AE, Dubinett SM, Burks EJ, Mazzilli SA, Lenburg ME, Beane JE. Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive disease. bioRxiv. 2025 Oct 06.View Related Profiles. PMID: 41278661; PMCID: PMC12632533; DOI: 10.1101/2025.10.04.680402;
     
Showing 10 of 68 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 68 publications over 19 distinct years, with a maximum of 14 publications in 2021

YearPublications
19981
20001
20031
20042
20052
20062
20121
20144
20152
20173
20181
20191
20208
202114
20226
20232
20244
20256
20267

Contact for Mentoring:

670 Albany Street
Boston MA 02118
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