Unraveling the superficial white matter of the primate brain: Tracer-based histology and dMRI tractography validation07/01/2022 - 06/30/2027 (Multi-PI)
PI:
Douglas L. Rosene, PhDNIH/National Institute of Neurological Disorders & Stroke5R01NS125307-02
Optimization and validation of quantitative birefringence microscopy for assessment of myelin pathologies associated with cognitive impairments and motor deficits in young and old aging monkey brain01/01/2022 - 11/30/2026 (Multi-PI)
PI:
Douglas L. Rosene, PhDNIH/National Institute on Aging5R01AG075727-02
Neural Substrates of Diffusion Imaging in Cognitively Aging Rhesus Monkeys08/15/2019 - 04/30/2024 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIA5R01AG042512-09
Age-related cognitive decline and myelin pathology: A comprehensive study of oligodendroglia, microglia and myelin homeostasis in the normal aging monkey05/15/2019 - 03/31/2024 (PI)
NIH/National Institute on Aging1RF1AG062831-01
Mechanisms of myelin damage and cognitive impairment in the aging monkey: Gene Expression, Neurophysiology, Inflammation and Effects of Calorie Restriction02/15/2019 - 01/31/2024 (PI)
NIH/National Institute on Aging2RF1AG043640-06
Neural dynamics underlying integration of sensory, reward and motor effort information in the macaque brain01/15/2020 - 01/14/2023 (Key Person / Mentor)
PI:
Chandramouli Chandrasekaran, PhDBrain & Behavior Research Foundation
Recovery of Motor Function Impaired by Cortical Injury: An Exploratory Comparison of the influences of Four Different Post-injury Treatments on Processes Affecting Neuroplasticity04/01/2019 - 03/31/2022 (Multi-PI)
PI:
Douglas L. Rosene, PhDNIH/National Institute of Neurological Disorders & Stroke1R21NS111174-01
White Matter Pathology and Infiltrating T cells in the Brain of Cognitively Impaired Aging Rhesus Monkeys02/01/2019 - 11/30/2021 (PI)
NIH/National Institute on Aging5R21AG061678-02
Collaborative Research: Unraveling Cerebral Connectivity with Diffusion MRI, Microscopy and Statistical Physics08/15/2015 - 01/31/2021 (Co-Investigator)
National Science FoundationPHY-1505000
Neural Substrates of Diffusion Imaging in Cognitively Aging Rhesus Monkeys06/01/2016 - 05/31/2019 (Multi-PI)
PI:
Douglas L. Rosene, PhDThe Brigham and Women's Hospital, Inc. NIH NIA5R01AG042512-05
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Effects of Curcumin on Frontal Circuitry in Aging Monkeys using MRI Connectome05/01/2016 - 04/30/2019 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NCCIH5R21AT008865-02
Translational Development of Glial Growth Factor 2 (GGF2) for the Treatment of St09/01/2017 - 07/31/2018 (PI)
NIH/National Institute of Neurological Disorders & Stroke7U01NS076474-03
Histopathology, Neuroimaging, and Mechanism of Myelin Damage in Aging Monkey Brain06/15/2016 - 04/30/2018 (PI)
NIH/National Institute on Aging5R01AG043640-05
Translational Development of GGF2 as a Stroke Recovery Therapeutic08/01/2016 - 08/01/2017 (Multi-PI)
PI:
Douglas L. Rosene, PhDAcorda Therapeutics, Inc. NIH NINDS5U01NS076474-02
Neural Substrates of Diffusion Imaging in Cognitively Aging Rhesus Monkeys09/15/2013 - 05/31/2016 (Multi-PI)
PI:
Douglas L. Rosene, PhDThe Brigham and Women's Hospital, Inc. NIH NIA5R01AG042512-03
Histopathology, Neuroimaging, and Mechanism of Myelin Damage in Aging Monkey Brain08/01/2013 - 04/30/2016 (PI)
NIH/National Institute on Aging5R01AG043640-03
The Human Connectome Project (HCP)09/01/2013 - 08/31/2015 (Subcontract PI)
Massachusetts General Hospital NIH NIMH5U01MH093765-05
Quantitative Analysis of Cerebral Cortex in Aging Monkeys08/01/2008 - 07/31/2015 (Co-Investigator)
PI:
H. Eugene Stanley, PhDNIH/National Institute on Aging5R01AG021133-08
Diffusion MRI of Complex White Matter and Connectivity06/01/2010 - 01/31/2015 (Subcontract PI)
Massachusetts General Hospital NIH NIMH5R01MH064044-09
Neural Substrates of Cognitive Decline in Aging Monkeys04/01/2007 - 03/31/2014 (PI)
NIH/National Institute on Aging5P01AG000001-34S1
MALNUTRITION AND MENTAL HEALTH: A RAT MODEL09/01/2010 - 06/30/2013 (Subcontract PI)
Judge Baker Children's Center (Harvard affiliate) NIH NIMH5R01MH074811-05
Neurobiological Consequences of Hypertension and Age03/01/2000 - 02/28/2010 (Co-PI)
NIH/National Institute on Aging5 R37 AG17609 10
Memory/Executive Systems in Prefrontal & Temporal Cortex12/01/2003 - 11/30/2008 (Co-PI)
NIH/National Institute of Mental Health5 R01 MH69686 05
Prenatal Malnutrition and Mental Retardation06/03/1999 - 04/30/2006 (Co-PI)
NIH/National Institute of Child Health & Human Development5 P01 HD22539 15
Minority Predoctoral Fellowship Program01/01/2003 - 10/31/2005 (Dept Sponsor)
NIH/National Institute on Aging5 F31 AG21873 03
Development of a Model of Cortical Stroke and Recovery07/01/2002 - 10/31/2004 (PI)
ViaCell, Inc.
Minority Predoctoral Fellowship Program07/01/2000 - 04/30/2003 (Dept Sponsor)
NIH/National Institute on Aging5 F31 AG05897 03
Hippocampal and Prefrontal Cortex Interactions in Cognition04/01/2000 - 03/31/2001 (Co-PI)
PI:
Mark B. Moss, PhDNational Science FoundationIOS-9982889