Associate Professor Ngo trained as a pharmacist at the University of South Australia. She spent the first years of her career working as a hospital medical information and clinical pharmacist. She completed her B. Health Science Honours degree and PhD at the University of Adelaide.
Associate Professor Ngo’s PhD was on the pathogenesis of aortic valve stenosis and resulted in several key discoveries: new echocardiographic method of quantitating early disease, first evidence of benefit of ACE-inhibitors in slowing the progression of the disease and characterisation of predictors of development of early disease in humans.
She then completed a postdoctoral fellowship at the University of California, Los Angeles, on redox biology and atrial fibrillation before returning to Adelaide in 2009 to establish a cardiovascular health and vitamin D research group at the Basil Hetzel Institute as an emerging cardiovascular research leader.
In 2012 she went to Boston Medical Centre to take up a position as a senior Postdoctoral Fellow working in the field of obesity and cardiometabolic health. During her tenure Associate Professor Ngo made fundamental discoveries related to angiogenesis regulation of adipose tissue and its effects on vasculature in general: her research was published in several cardiovascular and medical research journals including Circulation, Nature Medicine, Diabetes and ATVB.
She returned to Australia in 2015 as a Hospital Research Foundation Mid-Career Fellow and Senior Lecture, University of Adelaide.
In partnership with Associate Professor Aaron Sverdlov, she established and co-led Cardiometabolic research group at the Basil Hetzel Institute in Adelaide. Over two years they attracted over $720,000 in research funding across a variety of cardiovascular areas, including obesity and angiogenesis, weight loss and exercise physiology, novel biomarkers and cardio-oncology.
Associate Professor Ngo relocated to Newcastle in 2017 to take up a position with the School of Biomedical Sciences and Pharmacy and co-leader of Cariometabolic and Cardio-oncology research groups.
She has trained and supervised numerous vocational, honours and PhD students and continues to do so both in Adelaide and Newcastle. She has had 47 career publications. Her work has been cited over 830 times.
Postdoctoral Fellow (Previously held)
Boston University School of Medicine
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Figtree GA, Ngo DTM, Bubb KJ. Testosterone to estradiol ratio and plaque inflammation: mechanistic insights and biomarker potential? Cardiovasc Res. 2019 02 01; 115(2):255-257. PMID: 30395210
Ngo DTM, Sverdlov AL, Karki S, Macartney-Coxson D, Stubbs RS, Farb MG, Carmine B, Hess DT, Colucci WS, Gokce N. Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E168-E177.View Related Profiles. PMID: 30576243
Surikow SY, Nguyen TH, Stafford I, Chapman M, Chacko S, Singh K, Licari G, Raman B, Kelly DJ, Zhang Y, Waddingham MT, Ngo DT, Bate AP, Chua SJ, Frenneaux MP, Horowitz JD. Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome. JACC Basic Transl Sci. 2018 Apr; 3(2):213-226. PMID: 30062207
Amarasekera AT, Assadi-Khansari B, Liu S, Black M, Dymmott G, Rogers NM, Sverdlov AL, Horowitz JD, Ngo DTM. Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults. PLoS One. 2017; 12(5):e0174435.View Related Profiles. PMID: 28489857
Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206.View Related Profiles. PMID: 28411232; DOI: 10.1152/ajpheart.00776.2016;
Canavese M, Ngo DT, Maddern GJ, Hardingham JE, Price TJ, Hauben E. Biology and therapeutic implications of VEGF-A splice isoforms and single-nucleotide polymorphisms in colorectal cancer. Int J Cancer. 2017 May 15; 140(10):2183-2191. PMID: 27943279; DOI: 10.1002/ijc.30567;
Chen D, Procter N, Goh V, Liu S, Chua SJ, Assadi-Khansari B, Stewart S, Horowitz JD, Sverdlov AL, Ngo DT. New onset atrial fibrillation is associated with elevated galectin-3 levels. Int J Cardiol. 2016 Nov 15; 223:48-49.View Related Profiles. PMID: 27529590; DOI: 10.1016/j.ijcard.2016.08.172;
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