David J. Waxman, PhD
Professor
Boston University
Biology

PhD, Harvard University
AM, Harvard University
BA, Queens College, City University of New York



David J. Waxman, PhD is a Biologist with extensive experience in the fields of biochemistry, molecular biology, and enzymology. Over the past 35 years, his lab has made seminal contributions to the research of cancer pharmacology and therapeutics, and steroid-metabolizing enzymes.
Dr. Waxman has spoken at over 130 conferences and has held appointments at a variety of universities including Harvard Medical School, MIT, and the Weizmann Institute.

Member
Boston University
Genome Science Institute


Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Gastroenterology

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Hormonal control of NASH development and progression
09/01/2023 - 08/31/2027 (PI)
Department of Veterans Affairs


Probing co-transcriptional gene regulatory logics in human transcriptomes
08/01/2022 - 07/31/2027 (Key Person / Mentor)
NIH/National Institute of General Medical Sciences
5R35GM147254-02

Growth Hormone Regulation of Sex Differences in Liver Metabolism
06/19/2019 - 05/31/2025 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK121998-05

Xenobiotic-responsive hepatic long non-coding RNAs
07/07/2020 - 04/30/2025 (PI)
NIH/National Institute of Environmental Health Sciences
3R01ES024421-10S1

Epigenetic Actions of Environmental Chemicals
08/15/2014 - 07/06/2020 (PI)
NIH/National Institute of Environmental Health Sciences
5R01ES024421-05

Regulation of Sex Differences in Liver Metabolism
09/01/2018 - 09/15/2019 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
2R56DK033765-35A1

Regulation of Sex Differences in Liver Metabolism
02/01/2016 - 08/31/2018 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK033765-34

Regulation of Sex Differences in Liver Metabolism
02/01/2013 - 01/31/2016 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK033765-32S1

Combination Therapies for Cancer Treatment
12/07/2009 - 11/30/2015 (PI)
NIH/National Cancer Institute
5R01CA049248-24

IGERT: INTEGRATING COMPUTATIONAL SCIENCE INTO RESEARCH IN BIOLOGICAL NETWORKS
07/01/2007 - 06/30/2014 (Co-Investigator)
National Science Foundation
DGE-0654108

Showing 10 of 12 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Xenobiotic-responsive hepatic long non-coding RNAs 3R01ES024421-10S1
2024 Xenobiotic-responsive hepatic long non-coding RNAs 5R01ES024421-10
2023 Xenobiotic-responsive hepatic long non-coding RNAs 3R01ES024421-08S1
2023 Growth Hormone Regulation of Sex Differences in Liver Metabolism 5R01DK121998-05
2023 Xenobiotic-responsive hepatic long non-coding RNAs 5R01ES024421-09
2023 Xenobiotic-responsive hepatic long non-coding RNAs 3R01ES024421-09S1
2022 Growth Hormone Regulation of Sex Differences in Liver Metabolism 5R01DK121998-04
2022 Xenobiotic-responsive hepatic long non-coding RNAs 5R01ES024421-08
2021 Growth Hormone Regulation of Sex Differences in Liver Metabolism 5R01DK121998-03
2021 Xenobiotic-responsive hepatic long non-coding RNAs 5R01ES024421-07 7
Showing 10 of 104 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Rampersaud A, Connerney J, Waxman DJ. Plasma growth hormone pulses induce male-biased pulsatile chromatin opening and epigenetic regulation in adult mouse liver. Elife. 2023 Dec 13; 12. PMID: 38091606; PMCID: PMC10721219; DOI: 10.7554/eLife.91367;
     
  2. Rampersaud A, Connerney J, Waxman DJ. Plasma Growth Hormone Pulsatility Directly Regulates Male-biased Chromatin Accessibility in Adult Mouse Liver. bioRxiv. 2023 Aug 22. PMID: 37662275; PMCID: PMC10473588; DOI: 10.1101/2023.08.21.554153;
     
  3. Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis. Metabolism. 2023 Jul; 144:155589. PMID: 37182789; PMCID: PMC10843389; DOI: 10.1016/j.metabol.2023.155589;
     
  4. Karri K, Waxman DJ. TCDD dysregulation of lncRNA expression, liver zonation and intercellular communication across the liver lobule. Toxicol Appl Pharmacol. 2023 Jul 15; 471:116550. PMID: 37172768; PMCID: PMC10330769; DOI: 10.1016/j.taap.2023.116550;
     
  5. Everton E, Del Rio-Moreno M, Villacorta-Martin C, Singh Bawa P, Lindstrom-Vautrin J, Muramatsu H, Rizvi F, Smith AR, Tam Y, Pardi N, Kineman R, Waxman DJ, Gouon-Evans V. Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury. bioRxiv. 2023 Apr 18.View Related Profiles. PMID: 37131727; PMCID: PMC10153200; DOI: 10.1101/2023.04.17.537197;
     
  6. Karri K, Waxman DJ. Dysregulation of murine long noncoding single-cell transcriptome in nonalcoholic steatohepatitis and liver fibrosis. RNA. 2023 Jul; 29(7):977-1006. PMID: 37015806; PMCID: PMC10275269; DOI: 10.1261/rna.079580.123;
     
  7. Karri K, Waxman DJ. TCDD dysregulation of lncRNA expression, liver zonation and intercellular communication across the liver lobule. bioRxiv. 2023 Jan 08. PMID: 36711947; PMCID: PMC9881922; DOI: 10.1101/2023.01.07.523119;
     
  8. Waxman DJ, Kineman RD. Sex matters in liver fat regulation. Science. 2022 Oct 21; 378(6617):252-253. PMID: 36264790
     
  9. Kim D, Kim B, Brocker CN, Karri K, Waxman DJ, Gonzalez FJ. Long non-coding RNA G23Rik attenuates fasting-induced lipid accumulation in mouse liver. Mol Cell Endocrinol. 2022 Nov 01; 557:111722. PMID: 35917881; PMCID: PMC9561029; DOI: 10.1016/j.mce.2022.111722;
     
  10. Goldfarb CN, Karri K, Pyatkov M, Waxman DJ. Interplay Between GH-regulated, Sex-biased Liver Transcriptome and Hepatic Zonation Revealed by Single-Nucleus RNA Sequencing. Endocrinology. 2022 Jul 01; 163(7). PMID: 35512247; PMCID: PMC9154260; DOI: 10.1210/endocr/bqac059;
     
Showing 10 of 357 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 357 publications over 43 distinct years, with a maximum of 26 publications in 2006

YearPublications
19802
19823
19832
19841
19855
19867
19879
19887
198915
199014
199110
199210
199310
199413
19957
19968
19978
199816
199916
200013
200110
20025
20038
200413
200510
200626
200710
20089
20097
20109
20116
20126
20136
20145
20156
20167
20174
20185
20194
20207
20214
20227
20237


2018 American Society for Pharmacology and Experimental Therapeutics (ASPET): The Bernard B. Brodie Award in Drug Metabolism for Research
1993 Burroughs-Wellcome Endocrine Toxicology Symposium Lectureship
1983 Research Corporation Award
1981-1983 NIH NRSA Postdoctoral Fellowship Award
1980-1981 Damon Runyon-Walter Winchell Cancer Fund Fellowship
Contact for Mentoring:

5 Cummington St
Boston MA 02215
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