David L. Swain
Predoctoral Trainee
Boston University School of Medicine
Dept of Anatomy & Neurobiology

Predoctoral Trainee
Boston University School of Medicine

The Role of Giant Vacuoles and Pores of Schlemm's Canal Endothelial Cells in Regulating Aqueous Outflow
01/01/2020 - 12/31/2023 (PI)
NIH/National Eye Institute


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Swain DL, Yasmin S, Fernandes B, Lamaj G, Su Y, Gong H. Schlemm's Canal Endothelium Cellular Connectivity in Giant Vacuole and Pore Formation in Different Flow-type Areas: A Serial Block-Face Scanning Electron Microscopy Study. Front Cell Dev Biol. 2022; 10:867376. PMID: 35493087; PMCID: PMC9043561; DOI: 10.3389/fcell.2022.867376;
  2. Sosnowik S, Swain DL, Fan S, Toris CB, Gong H. Morphological changes to Schlemm's canal and the distal aqueous outflow pathway in monkey eyes with laser-induced ocular hypertension. Exp Eye Res. 2022 Mar 10; 219:109030.View Related Profiles. PMID: 35283108; DOI: 10.1016/j.exer.2022.109030;
  3. Ren R, Humphrey AA, Swain DL, Gong H. Relationships between Intraocular Pressure, Effective Filtration Area, and Morphological Changes in the Trabecular Meshwork of Steroid-Induced Ocular Hypertensive Mouse Eyes. Int J Mol Sci. 2022 Jan 13; 23(2).View Related Profiles. PMID: 35055036; PMCID: PMC8775853; DOI: 10.3390/ijms23020854;
  4. Swain DL, Le TD, Yasmin S, Fernandes B, Lamaj G, Dasgupta I, Gao Y, Gong H. Morphological factors associated with giant vacuoles with I-pores in Schlemm's canal endothelial cells of human eyes: A serial block-face scanning electron microscopy study. Exp Eye Res. 2021 04; 205:108488.View Related Profiles. PMID: 33571532; PMCID: PMC8044056; DOI: 10.1016/j.exer.2021.108488;
  5. Wang Y, Xin C, Li M, Swain DL, Cao K, Wang H, Wang N. Macular vessel density versus ganglion cell complex thickness for detection of early primary open-angle glaucoma. BMC Ophthalmol. 2020 Jan 08; 20(1):17. PMID: 31914956; PMCID: PMC6950925; DOI: 10.1186/s12886-020-1304-x;
  6. Gong H and Swain DL. Anatomy of the conventional aqueous outflow pathway. In: Samples JR, Ahmed IIK (eds). Current Developments in Glaucoma Surgery and MIGS. Kugler Publications. Amsterdam. 2020; 1:1-38. View Publication
  7. Lai J, Su Y, Swain DL, Huang D, Getchevski D, Gong H. The Role of Schlemm's Canal Endothelium Cellular Connectivity in Giant Vacuole Formation: A 3D Electron Microscopy Study. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1630-1643.View Related Profiles. PMID: 30995299; PMCID: PMC6736380; DOI: 10.1167/iovs.18-26011;
  8. Gong H and Swain DL. The histopathological changes in the trabecular outflow pathway and their possible effects on aqueous outflow in eyes with primary open-angle glaucoma. In: Knepper PA, Samples JR (eds). Glaucoma Research and Clinical Advances: 2016 to 2018. Kugler Publications. Amsterdam. 2016; 1:17-40. View Publication
  9. Swain DL, Ho J, Lai J, Gong H. Shorter scleral spur in eyes with primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2015 Mar; 56(3):1638-48.View Related Profiles. PMID: 25670488; PMCID: PMC4351652; DOI: 10.1167/iovs.14-15593;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 9 publications over 6 distinct years, with a maximum of 3 publications in 2022


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72 E. Concord St Instructional (L)
Boston MA 02118
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