Ching-Ti Liu, PhD
Professor
Boston University School of Public Health
Biostatistics

PhD, University of California, Los Angeles
MS, University of California, Los Angeles
MS, National Central University
BS, National Central University



Dr. Liu's research interest mainly focuses on the development of statistical and computational approaches for genetics/genomics and bioinformatics studies. He also collaborates as a statistician or statistical geneticist on projects studying complex diseases such as diabetes, obesity, musculoskeletal disorder, and cancer. Dr. Liu has more than 10-year experience working on Framingham Heart Study (FHS) as a biostatistician collaborating on various projects. Dr. Liu has also functioned as a collaborator on traditional epidemiological, biomedical or basic science research beyond FHS. In addition, Dr. Liu has been actively engaged in several international collaborative consortia for the analysis of genetics and genomics data.

Investigator
Framingham Heart Study




Novel Molecular Biomarkers of Bone Microarchitecture
04/01/2021 - 03/31/2026 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIAMS
5R01AR041398-29

TOPMed Omics of Type 2 Diabetes and Quantitative Traits
01/01/2021 - 12/31/2025 (Subcontract PI)
Massachusetts General Hospital NIH NIDDK
5UM1DK078616-16

Vascular mechanisms underlying skeletal fragility in older Adults
12/15/2020 - 11/30/2025 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIA
5R01AG065299-04

Integrative Approaches to Identifying Function and Clinical Significance of Adiposity Susceptibility Genes
09/22/2020 - 07/31/2025 (Subcontract PI)
University of North Carolina at Chapel Hill NIH NIDDK
5R01DK122503-05

TOPMed Omics of Cardiovascular Disease in Diabetes
07/01/2020 - 06/30/2025 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
5R01HL151855-04

Assessing the role and importance of race and ethnicity in the clinical algorithm for predicting ASCVD
04/01/2024 - 03/31/2025 (Key Person / Mentor)
American Heart Association


A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits
04/27/2021 - 03/31/2025 (Subcontract PI)
The Washington University NIH NHLBI
5R01HL156991-04

Identifying osteoporosis genes by whole genome sequencing and functional validation in Zebra Fish
09/01/2017 - 07/31/2023 (Subcontract PI)
Hebrew SeniorLife NIH NIAMS
5R01AR072199-05

TOPMed Contribution to the AMP-T2D Knowledge Portal
04/01/2019 - 05/31/2021 (PI)
Foundation for the National Institutes of Health


Risk Factors for Age-Related Bone Loss
06/01/2016 - 05/31/2021 (Subcontract PI)
Hebrew SeniorLife NIH NIAMS
5R01AR041398-23

Showing 10 of 16 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Li X, Chen H, Selvaraj MS, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Jiang MZ, DiCorpo D, Gaynor SM, Dey R, Arnett DK, Benjamin EJ, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Carson AP, Carlson JC, Chami N, Chen YI, Curran JE, de Vries PS, Fornage M, Franceschini N, Freedman BI, Gu C, Heard-Costa NL, He J, Hou L, Hung YJ, Irvin MR, Kaplan RC, Kardia SLR, Kelly TN, Konigsberg I, Kooperberg C, Kral BG, Li C, Li Y, Lin H, Liu CT, Loos RJF, Mahaney MC, Martin LW, Mathias RA, Mitchell BD, Montasser ME, Morrison AC, Naseri T, North KE, Palmer ND, Peyser PA, Psaty BM, Redline S, Reiner AP, Rich SS, Sitlani CM, Smith JA, Taylor KD, Tiwari HK, Vasan RS, Viali S, Wang Z, Wessel J, Yanek LR, Yu B, Dupuis J, Meigs JB, Auer PL, Raffield LM, Manning AK, Rice KM, Rotter JI, Peloso GM, Natarajan P, Li Z, Liu Z, Lin X. A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. Nat Comput Sci. 2025 Feb; 5(2):125-143.View Related Profiles. PMID: 39920506
     
  2. Florea VV, Gajjar P, Huang S, Tang J, Zhao S, Davenport M, Mi MY, Haff M, Zhang X, Miller PE, Vasan RS, Liu CT, Lewis GD, Shah RV, Long MT, Nayor M. Hepatic Steatosis and Fibrosis, Cardiorespiratory Fitness, and Metabolic Mediators in the Community. Liver Int. 2025 Jan; 45(1):e16147.View Related Profiles. PMID: 39673712; PMCID: PMC11649011; DOI: 10.1111/liv.16147;
     
  3. Anwar MY, Highland H, Buchanan VL, Graff M, Young K, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson CW, Aguet F, Ardlie KG, Gerszten RE, Clish CB, Lange LA, Ding J, Goodarzi MO, Chen YI, Peloso GM, Guo X, Stanislawski MA, Rotter JI, Rich SS, Justice AE, Liu CT, North K. Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns. Obesity (Silver Spring). 2024 Nov; 32(11):2024-2034.View Related Profiles. PMID: 39497627; PMCID: PMC11540333; DOI: 10.1002/oby.24137;
     
  4. Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H, Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN. Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nat Commun. 2024 Oct 03; 15(1):8549.View Related Profiles. PMID: 39362880; PMCID: PMC11450065; DOI: 10.1038/s41467-024-52579-w;
     
  5. Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K, Bartz TM, de las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most P, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Abu Yusuf Ansari M, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Gu CC, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Evans M, Fornage M, Fox ER, Franceschini N, Harlow SD, Holliday E, Ikram MA, Kelly T, Lakka TA, Lawlor DA, Li C, Liu CT, Mägi R, Manning AK, Matsuda F, Morrison AC, Nauck M, North KE, Penninx BW, Province MA, Psaty BM, Rotter JI, Spector TD, Wagenknecht LE, Willems van Dijk K, Study LC, Jaquish CE, Wilson PW, Peyser PA, Munroe PB, de Vries PS, Gauderman WJ, Sun YV, Chen H, Miller CL, Winkler TW, Rao DC, Redline S, van Heemst D. A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances. medRxiv. 2024 Sep 04.View Related Profiles. PMID: 39281768; PMCID: PMC11398441; DOI: 10.1101/2024.09.02.24312466;
     
  6. Usiskin IM, Mitchell GF, Bouxsein ML, Liu CT, Kiel DP, Samelson EJ. Vascular function and skeletal fragility: a study of tonometry, brachial hemodynamics, and bone microarchitecture. J Bone Miner Res. 2024 Aug 05; 39(7):906-917. PMID: 38709885; PMCID: PMC11301519; DOI: 10.1093/jbmr/zjae071;
     
  7. Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, Lee S, Wang W, Brown M, Morrison J, Giri A, O'Connell J, Bartz T, Fuentes LL, Gudmundsdottir V, Guo X, Harris S, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer N, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most P, Wang Y, Weiss S, Westerman K, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja A, Arzt M, Aschard H, Attia J, Bazzano L, Breyer M, Brody J, Cade B, Chen HH, Chen YI, Chen Z, de Vries P, Dimitrov L, Do A, Du J, Dupont C, Edwards T, Evans M, Faquih T, Felix S, Fisher-Hoch S, Floyd J, Graff M, Gu CC, Gu D, Hairston K, Hanley A, Heid I, Heikkinen S, Highland H, Hood M, Kähönen M, Karvonen-Gutierrez C, Kawaguchi T, Kazuya S, Tanika K, Komulainen P, Levy D, Lin H, Liu P, Marques-Vidal P, McCormick J, Mei H, Meigs J, Menni C, Nam K, Nolte I, Pacheco N, Petty L, Polikowsky H, Province M, Psaty B, Raffield L, Raitakari O, Rich S, Riha R, Risch L, Risch M, Ruiz-Narvaez E, Scott R, Sitlani C, Smith J, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson O, Xia R, Yao J, Young K, Zhang R, Zhu X, Below J, Böger C, Conen D, Cox S, Dörr M, Feitosa M, Fox E, Franceschini N, Gharib S, Gudnason V, Harlow S, He J, Holliday E, Kutalik Z, Lakka T, Lawlor D, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison A, Penninx BWJH, Peyser P, Rotter J, Snieder H, Spector T, Wagenknecht L, Wareham N, Zonderman A, North K, Fornage M, Hung A, Manning A, Gauderman W, Chen H, Munroe P, Rao D, van Heemst D, Redline S, Noordam R. A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. Res Sq. 2024 Jul 17. PMID: 39070651; PMCID: PMC11276021; DOI: 10.21203/rs.3.rs-4163414/v1;
     
  8. Xu H, Gupta S, Dinsmore I, Kollu A, Cawley AM, Anwar MY, Chen HH, Petty LE, Seshadri S, Graff M, Below P, Brody JA, Chittoor G, Fisher-Hoch SP, Heard-Costa NL, Levy D, Lin H, Loos RJ, Mccormick JB, Rotter JI, Mirshahi T, Still CD, Destefano A, Cupples LA, Mohlke KL, North KE, Justice AE, Liu CT. Integrating Genetic and Transcriptomic Data to Identify Genes Underlying Obesity Risk Loci. medRxiv. 2024 Jun 12.View Related Profiles. PMID: 38903089; PMCID: PMC11188121; DOI: 10.1101/2024.06.11.24308730;
     
  9. Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB. Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes. Diabetes Care. 2024 Jun 01; 47(6):1042-1047.View Related Profiles. PMID: 38652672; PMCID: PMC11116923; DOI: 10.2337/dc23-2274;
     
  10. Xin Z, Xu H, Zhang X, Samelson EJ, Kiel DP, Liu CT. Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study : Bone fracture and 30-year BMI trajectories. Osteoporos Int. 2024 Jul; 35(7):1205-1212. PMID: 38587675; PMCID: PMC11488984; DOI: 10.1007/s00198-024-07068-7;
     
Showing 10 of 218 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 218 publications over 20 distinct years, with a maximum of 29 publications in 2018

YearPublications
20042
20072
20081
20093
20101
20115
201216
20137
201412
20154
201611
201713
201829
201923
202013
202118
202217
202325
202414
20252


2021 Boston University School of Public Health: Excellence in Teaching Award for Dedication to Student Learning
2020 American Statistical Association: Fellow of the American Statistical Association
2016 Boston University School of Public Health: Excellence in Teaching Award
2011 Boston University School of Public Health: Excellence in Teaching Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

statistical genetics, genomics, biostatistics, bioinformatics, obesity, diabetes, musculoskeletal disorders

Available to Mentor as: (Review Mentor Role Definitions):
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Contact for Mentoring:
  • Email (see 'Contact Info')

801 Massachusetts Ave Crosstown Center
Boston MA 02118
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