Ching-Ti Liu, PhD
Professor
Boston University School of Public Health
Biostatistics

PhD, University of California, Los Angeles
MS, University of California, Los Angeles
MS, National Central University
BS, National Central University



Dr. Liu's research interest mainly focuses on the development of statistical and computational approaches for genetics/genomics and bioinformatics studies. He also collaborates as a statistician or statistical geneticist on projects studying complex diseases such as diabetes, obesity, musculoskeletal disorder, and cancer. Dr. Liu has more than 10-year experience working on Framingham Heart Study (FHS) as a biostatistician collaborating on various projects. Dr. Liu has also functioned as a collaborator on traditional epidemiological, biomedical or basic science research beyond FHS. In addition, Dr. Liu has been actively engaged in several international collaborative consortia for the analysis of genetics and genomics data.

Investigator
Framingham Heart Study




Novel Molecular Biomarkers of Bone Microarchitecture
04/01/2021 - 03/31/2026 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIAMS
5R01AR041398-29

TOPMed Omics of Type 2 Diabetes and Quantitative Traits
01/01/2021 - 12/31/2025 (Subcontract PI)
Massachusetts General Hospital NIH NIDDK
5UM1DK078616-16

Vascular mechanisms underlying skeletal fragility in older Adults
12/15/2020 - 11/30/2025 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIA
5R01AG065299-04

Integrative Approaches to Identifying Function and Clinical Significance of Adiposity Susceptibility Genes
09/22/2020 - 07/31/2025 (Subcontract PI)
University of North Carolina at Chapel Hill NIH NIDDK
5R01DK122503-05

TOPMed Omics of Cardiovascular Disease in Diabetes
07/01/2020 - 06/30/2025 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
5R01HL151855-04

Assessing the role and importance of race and ethnicity in the clinical algorithm for predicting ASCVD
04/01/2024 - 03/31/2025 (Key Person / Mentor)
American Heart Association


A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits
04/27/2021 - 03/31/2025 (Subcontract PI)
The Washington University NIH NHLBI
5R01HL156991-04

Identifying osteoporosis genes by whole genome sequencing and functional validation in Zebra Fish
09/01/2017 - 07/31/2023 (Subcontract PI)
Hebrew SeniorLife NIH NIAMS
5R01AR072199-05

TOPMed Contribution to the AMP-T2D Knowledge Portal
04/01/2019 - 05/31/2021 (PI)
Foundation for the National Institutes of Health


Risk Factors for Age-Related Bone Loss
06/01/2016 - 05/31/2021 (Subcontract PI)
Hebrew SeniorLife NIH NIAMS
5R01AR041398-23

Showing 10 of 16 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Nomura S, Guan W, Zhang Y, Tison GH, Ikezaki H, Diffenderfer MR, Liu CT, Hoogeveen RC, Ballantyne CM, Schaefer EJ, Tsai MY. Lipoprotein(a) and Heart Failure Among Black and White Participants in Atherosclerosis Risk in Communities Study, Framingham Offspring Study, and Multi-Ethnic Study of Atherosclerosis: The Pooling Project. J Am Heart Assoc. 2025 Jun 03; 14(11):e038608. PMID: 40417812
     
  2. Zhang X, Su KJ, Banerjee B, Eres I, Hsu YH, Crandall CJ, Donaka R, Han Z, Jackson RD, Liu H, Luo Z, Mitchell BD, Qiu C, Tian Q, Shen H, Tsai MJ, Wiggins KL, Xu H, Yau M, Zhao LJ, Zhang X, Montasser ME, Kiel DP, Deng HW, Liu CT, Karasik D. Multi-ancestry whole genome sequencing analysis of lean body mass. Genome Biol. 2025 Apr 28; 26(1):106. PMID: 40296127; PMCID: PMC12036297; DOI: 10.1186/s13059-025-03520-x;
     
  3. Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NS, Meyer M, Gupta S, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Le Marchand L, McDonald MN, McHugh CP, Morrison AC, Naseri T, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Ida Chen YD, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Benjamin Shoemaker M, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Cupples LA, Lange LA, Liu CT, Loos RJF, North KE, Justice AE. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun. 2025 Apr 11; 16(1):3470.View Related Profiles. PMID: 40216759; PMCID: PMC11992084; DOI: 10.1038/s41467-025-58420-2;
     
  4. Hoogeveen RC, Diffenderfer MR, Lim E, Liu CT, Ikezaki H, Guan W, Tsai MY, Ballantyne CM. Lipoprotein(a) and Risk of Incident Atherosclerotic Cardiovascular Disease: Impact of High-Sensitivity C-Reactive Protein and Risk Variability Among Human Clinical Subgroups. Nutrients. 2025 Apr 11; 17(8). PMID: 40284189; PMCID: PMC12030245; DOI: 10.3390/nu17081324;
     
  5. Nagarajan P, Winkler TW, Bentley AR, Miller CL, Kraja AT, Schwander K, Lee S, Wang W, Brown MR, Morrison JL, Giri A, O'Connell JR, Bartz TM, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris SE, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer ND, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most PJ, Wang Y, Weiss S, Westerman KE, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja AD, Arzt M, Aschard H, Attia JR, Bazzanno L, Breyer MA, Brody JA, Cade BE, Chen HH, Chen YI, Chen Z, de Vries PS, Dimitrov LM, Do A, Du J, Dupont CT, Edwards TL, Evans MK, Faquih T, Felix SB, Fisher-Hoch SP, Floyd JS, Graff M, Gu C, Gu D, Hairston KG, Hanley AJ, Heid IM, Heikkinen S, Highland HM, Hood MM, Kähönen M, Karvonen-Gutierrez CA, Kawaguchi T, Kazuya S, Kelly TN, Komulainen P, Levy D, Lin HJ, Liu PY, Marques-Vidal P, McCormick JB, Mei H, Meigs JB, Menni C, Nam K, Nolte IM, Pacheco NL, Petty LE, Polikowsky HG, Province MA, Psaty BM, Raffield LM, Raitakari OT, Rich SS, Riha RL, Risch L, Risch M, Ruiz-Narvaez EA, Scott RJ, Sitlani CM, Smith JA, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, Willems van Dijk K, Wilson OD, Xia R, Yao J, Young KL, Zhang R, Zhu X, Below JE, Böger CA, Conen D, Cox SR, Dörr M, Feitosa MF, Fox ER, Franceschini N, Gharib SA, Gudnason V, Harlow SD, He J, Holliday EG, Kutalik Z, Lakka TA, Lawlor DA, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison AC, Penninx BW, Peyser PA, Rotter JI, Snieder H, Spector TD, Wagenknecht LE, Wareham NJ, Zonderman AB, North KE, Fornage M, Hung AM, Manning AK, Gauderman J, Chen H, Munroe PB, Rao DC, van Heemst D, Redline S, Noordam R, Wang H. A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations. Mol Psychiatry. 2025 Apr 04. PMID: 40181193
     
  6. Ai M, Otokozawa S, Liu CT, Asztalos BF, Maddalena J, Diffenderfer MR, Russo G, Thongtang N, Dansinger ML. Diabetes Mellitus Risk Prediction in the Framingham Offspring Study and Large Population Analysis. Nutrients. 2025 Mar 24; 17(7). PMID: 40218874; PMCID: PMC11990307; DOI: 10.3390/nu17071117;
     
  7. Sevilla-González M, Smith K, Wang N, Jensen AE, Litkowski EM, Kim H, DiCorpo DA, Hsu S, Cui J, Liu CT, Yu C, McNeil JJ, Lacaze P, Westerman KE, Chang KM, Tsao PS, Phillips LS, Goodarzi MO, Sladek R, Rotter JI, Dupuis J, Florez JC, Merino J, Meigs JB, Zhou JJ, Raghavan S, Udler MS, Manning AK. Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes. Nat Commun. 2025 Mar 15; 16(1):2569.View Related Profiles. PMID: 40089507; PMCID: PMC11910595; DOI: 10.1038/s41467-025-57452-y;
     
  8. Orchard P, Blackwell TW, Kachuri L, Castaldi PJ, Cho MH, Christenson SA, Durda P, Gabriel S, Hersh CP, Huntsman S, Hwang S, Joehanes R, Johnson M, Li X, Lin H, Liu CT, Liu Y, Mak ACY, Manichaikul AW, Paik D, Saferali A, Smith JD, Taylor KD, Tracy RP, Wang J, Wang M, Weinstock JS, Weiss J, Wheeler HE, Zhou Y, Zoellner S, Wu JC, Mestroni L, Graw S, Taylor MRG, Ortega VE, Johnson CW, Gan W, Abecasis G, Nickerson DA, Gupta N, Ardlie K, Woodruff PG, Zheng Y, Bowler RP, Meyers DA, Reiner A, Kooperberg C, Ziv E, Ramachandran VS, Larson MG, Cupples LA, Burchard EG, Silverman EK, Rich SS, Heard-Costa N, Tang H, Rotter JI, Smith AV, Levy D, Aguet F, Scott L, Raffield LM, Parker SCJ. Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed. medRxiv. 2025 Feb 21.View Related Profiles. PMID: 40034763; PMCID: PMC11875316; DOI: 10.1101/2025.02.19.25322561;
     
  9. Lee S, Miller CL, Bentley AR, Brown MR, Nagarajan P, Noordam R, Morrison J, Schwander K, Westerman K, Kho M, Kraja AT, de Vries PS, Ammous F, Aschard H, Bartz TM, Do A, Dupont CT, Feitosa MF, Gudmundsdottir V, Guo X, Harris SE, Hikino K, Huang Z, Lefevre C, Lyytikäinen LP, Milaneschi Y, Nardone GG, Santin A, Schmidt H, Shen B, Sofer T, Sun Q, Tan YA, Tang J, Thériault S, van der Most PJ, Ware EB, Weiss S, Ya Xing W, Yu C, Zhao W, Ansari MAY, Anugu P, Attia JR, Bazzano LA, Bis JC, Breyer M, Cade B, Chen G, Collins S, Corley J, Davies G, Dörr M, Du J, Edwards TL, Faquih T, Faul JD, Fohner AE, Fretts AM, Gangireddy S, Gepner A, Graff M, Hofer E, Homuth G, Hood MM, Jie X, Kähönen M, Kardia SL, Karvonen-Gutierrez CA, Launer LJ, Levy D, Maheshwari M, Martin LW, Matsuda K, McNeil JJ, Nolte IM, Okochi T, Raffield LM, Raitakari OT, Risch L, Risch M, Roux AD, Ruiz-Narvaez EA, Russ TC, Saito T, Schreiner PJ, Scott RJ, Shikany J, Smith JA, Snieder H, Spedicati B, Tai ES, Taylor AM, Taylor KD, Tesolin P, van Dam RM, Wang R, Wenbin W, Xie T, Yao J, Young KL, Zhang R, Zonderman AB, Concas MP, Conen D, Cox SR, Evans MK, Fox ER, de Las Fuentes L, Giri A, Girotto G, Grabe HJ, Gu C, Gudnason V, Harlow SD, Holliday E, Jost JB, Lacaze P, Lee S, Lehtimäki T, Li C, Liu CT, Morrison AC, North KE, Penninx BW, Peyser PA, Province MM, Psaty BM, Redline S, Rosendaal FR, Rotimi CN, Rotter JI, Schmidt R, Sim X, Terao C, Weir DR, Zhu X, Franceschini N, O'Connell JR, Jaquish CE, Wang H, Manning A, Munroe PB, Rao DC, Chen H, Gauderman WJ, Bierut L, Winkler TW, Fornage M. A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations. Res Sq. 2025 Feb 17. PMID: 40034430; PMCID: PMC11875294; DOI: 10.21203/rs.3.rs-6025759/v1;
     
  10. Li X, Chen H, Selvaraj MS, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Jiang MZ, DiCorpo D, Gaynor SM, Dey R, Arnett DK, Benjamin EJ, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Carson AP, Carlson JC, Chami N, Chen YI, Curran JE, de Vries PS, Fornage M, Franceschini N, Freedman BI, Gu C, Heard-Costa NL, He J, Hou L, Hung YJ, Irvin MR, Kaplan RC, Kardia SLR, Kelly TN, Konigsberg I, Kooperberg C, Kral BG, Li C, Li Y, Lin H, Liu CT, Loos RJF, Mahaney MC, Martin LW, Mathias RA, Mitchell BD, Montasser ME, Morrison AC, Naseri T, North KE, Palmer ND, Peyser PA, Psaty BM, Redline S, Reiner AP, Rich SS, Sitlani CM, Smith JA, Taylor KD, Tiwari HK, Vasan RS, Viali S, Wang Z, Wessel J, Yanek LR, Yu B, Dupuis J, Meigs JB, Auer PL, Raffield LM, Manning AK, Rice KM, Rotter JI, Peloso GM, Natarajan P, Li Z, Liu Z, Lin X. A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. Nat Comput Sci. 2025 Feb; 5(2):125-143.View Related Profiles. PMID: 39920506; PMCID: PMC11981678; DOI: 10.1038/s43588-024-00764-8;
     
Showing 10 of 227 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 227 publications over 20 distinct years, with a maximum of 29 publications in 2018

YearPublications
20042
20072
20081
20093
20101
20115
201216
20137
201412
20154
201611
201713
201829
201923
202013
202118
202217
202325
202414
202511


2021 Boston University School of Public Health: Excellence in Teaching Award for Dedication to Student Learning
2020 American Statistical Association: Fellow of the American Statistical Association
2016 Boston University School of Public Health: Excellence in Teaching Award
2011 Boston University School of Public Health: Excellence in Teaching Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

statistical genetics, genomics, biostatistics, bioinformatics, obesity, diabetes, musculoskeletal disorders

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

801 Massachusetts Ave Crosstown Center
Boston MA 02118
Google Map


Liu's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department