Charlene J. Ong, MD, MPHS Hear my name
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine

MD, Columbia University College of Physicians and Surgeons
BA, University of Pennsylvania
BS, University of Pennsylvania

Pronouns: she/her/hers

Charlene Ong, MD, MPHS, is an Assistant Professor of Neurology and Neurosurgery at Chobanian and Avedisian School of Medicine (BUSM), and clinical Neurointensivist at Boston Medical Center (BMC), and a lecturer at Harvard Medical School. She received her undergraduate degree at University of Pennsylvania, her MD at Columbia University and her Master's in Population Health Sciences at Washington University School of Medicine. Her research focuses on the development and validation of data-driven tools to support clinical decision making in patients with catastrophic neurologic injury including ischemic and hemorrhagic stroke, traumatic brain injury and anoxic brain injury. She receives support from the National Institute of Health through a K-award, and has also received foundational support from the American Brain Foundation, Philips-MIT, Peter-Paul Career Development Committee and Boston University Center for Translational Science Institute. Through machine learning methods, understudied physiologic biomarkers, and dynamic multimodal risk prediction methods, she aims to reduce morbidity and optimize treatment decision making in patients with acute neurologic disease.

Diversity, Equity, Inclusion and Accessibility

I firmly believe that fostering an environment which invigorates students and trainees from a variety of backgrounds, including those who are underrepresented in STEM, improves our science and humanity.

2019-Pres Mentorship of students from races/ethnicities underrepresented in STEM

Assistant Professor
Boston University Chobanian & Avedisian School of Medicine

Visiting Scientist
Massachusetts Institute of Technology

Electrooculography signatures of arousal recovery after cardiac arrest
04/01/2023 - 03/31/2026 (PI)
American Heart Association/AHA

Dynamic Risk Prediction of Life-Threatening Mass Effect After Ischemic Stroke
04/01/2021 - 03/31/2026 (PI)
National Institute of Neurological Disorders and Stroke/NIH/DHHS

Race / Ethnicity and Control of Hypertension after Intracerebral Hemorrhage
01/01/2021 - 11/30/2022 (Multi-PI)
PI: Charlene J. Ong, MD, MPHS
Massachusetts General Hospital American Heart Assoc


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Stafford R, Chatzidakis S, Kim ISY, Zhang Y, Rina A, Brush B, Mian A, Abdalkader M, Greer DM, Smirnakis SM, Feske SK, Dupuis J, Ong CJ. Follow-up ASPECTS improves prediction of potentially lethal malignant edema in patients with large middle cerebral artery stroke. J Neurointerv Surg. 2023 Dec 30.View Related Profiles. PMID: 38160055
  2. Ong C, Huang Q, Kim I, Pohlmann J, Chatzidakis S, Brush B, Zhang Y, Du Y, Mallinger LA, Benjamin EJ, Dupuis J, Greer D, Smirnakis S, Trinquart L. Dynamic trajectories of life-threatening mass effect in patients with large middle cerebral artery stroke. Res Sq. 2023 Nov 20.View Related Profiles. PMID: 38045289; PMCID: PMC10690305; DOI: 10.21203/;
  3. Ong CJ. The prognostic potential of pupillometry in patients with acute brain injury. Lancet Neurol. 2023 Oct; 22(10):876-878. PMID: 37652069; PMCID: PMC10791071; DOI: 10.1016/S1474-4422(23)00314-9;
  4. Ong CJ. Quantitative Pupillometry: Not a Clear Predictor of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage. Neurocrit Care. 2023 Aug; 39(1):34-35. PMID: 37225940; PMCID: PMC10792537; DOI: 10.1007/s12028-023-01709-1;
  5. Hingorani KS, Barnes E, Carneiro T, Sader E, Anand P, Ong CJ, Chung D, Daneshmand A, Suchdev K, Takahashi C, Greer D, Shulman JG, Aparicio HJ, Nguyen TN, Romero JR, AbdalKader M, Feske SK, Kimmel SD, Weinstein ZM, Fagan M, Dobrilovic N, Awtry E, Cervantes-Arslanian AM. Strokes in Patients With Injection Drug Use and Tricuspid Valve Endocarditis - A Case Series. Neurohospitalist. 2023 Jul; 13(3):272-277.View Related Profiles. PMID: 37441214; PMCID: PMC10334046; DOI: 10.1177/19418744231159460;
  6. Dupre AE, Cronin MFM, Schmugge S, Tate S, Wack A, Prescott BR, Li C, Auerbach S, Suchdev K, Al-Faraj A, He W, Cervantes-Arslanian AM, Abdennadher M, Saxena A, Lehan W, Russo M, Pugsley B, Greer D, Shin M, Ong CJ. A machine learning eye movement detection algorithm using electrooculography. Sleep. 2023 Apr 12; 46(4).View Related Profiles. PMID: 36255119; DOI: 10.1093/sleep/zsac254;
  7. Chan WP, Prescott BR, Barra ME, Chung DY, Kim IS, Saglam H, Hutch MR, Shin M, Zafar SF, Benjamin EJ, Smirnakis SM, Dupuis J, Greer DM, Ong CJ. Dexmedetomidine and Other Analgosedatives Alter Pupil Characteristics in Critically Ill Patients. Crit Care Explor. 2022 May; 4(5):e0691.View Related Profiles. PMID: 35783547; PMCID: PMC9243241; DOI: 10.1097/CCE.0000000000000691;
  8. Miller MI, Orfanoudaki A, Cronin M, Saglam H, So Yeon Kim I, Balogun O, Tzalidi M, Vasilopoulos K, Fanaropoulou G, Fanaropoulou NM, Kalin J, Hutch M, Prescott BR, Brush B, Benjamin EJ, Shin M, Mian A, Greer DM, Smirnakis SM, Ong CJ. Natural Language Processing of Radiology Reports to Detect Complications of Ischemic Stroke. Neurocrit Care. 2022 Aug; 37(Suppl 2):291-302.View Related Profiles. PMID: 35534660; PMCID: PMC9986939; DOI: 10.1007/s12028-022-01513-3;
  9. Cervantes-Arslanian AM, Venkata C, Anand P, Burns JD, Ong CJ, LeMahieu AM, Schulte PJ, Singh TD, Rabinstein AA, Deo N, Bansal V, Boman K, Domecq Garces JP, Lee Armaignac D, Christie AB, Melamed RR, Tarabichi Y, Cheruku SR, Khanna AK, Denson JL, Banner-Goodspeed VM, Anderson HL, Gajic O, Kumar VK, Walkey A, Kashyap R. Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic. Crit Care Explor. 2022 Apr; 4(4):e0686.View Related Profiles. PMID: 35492258; PMCID: PMC9042584; DOI: 10.1097/CCE.0000000000000686;
  10. Prescott BR, Saglam H, Duskin JA, Miller MI, Thakur AS, Gholap EA, Hutch MR, Smirnakis SM, Zafar SF, Dupuis J, Benjamin EJ, Greer DM, Ong CJ. Anisocoria and Poor Pupil Reactivity by Quantitative Pupillometry in Patients With Intracranial Pathology. Crit Care Med. 2022 02 01; 50(2):e143-e153.View Related Profiles. PMID: 34637415; PMCID: PMC8810747; DOI: 10.1097/CCM.0000000000005272;
Showing 10 of 32 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 32 publications over 9 distinct years, with a maximum of 8 publications in 2020


2020-2021 Boston University: CTSI Pilot Grant
2020-2021 Boston University, Department of Neurology: Simon Grinspoon Grant
2020-2022 Boston University: KL2
2018 “Neurology on the Hill”: American Academy of Neurology
2018-2019 Massachusetts Institute of Technology: Philips-MIT Clinician Investigator Award
2018-2021 Boston University : Peter Paul Young Investigator Award
2017-2018 American Brain Foundation: American Brain Foundation Crowd-Sourcing Grant Award
2015 Washington University School of Medicine: Chief Resident of Education
2015-2016 American Academy of Neurology: Enhanced Leadership Award
2014 Washington University School of Medicine: Irwin Levy Teaching Prize
2014 Washington University School of Medicine: Resident of The Year
2012 Columbia University: Herbert J. Bartelstone Award in Pharmacology
2002 University of Pennsylvania: Benjamin Franklin Scholar
2002 Wharton School of Business: Joseph Wharton Scholar

I am an Assistant Professor in the Department of Neurology and Neurocritical Care Physician at Boston University School of Medicine. I am also a Visiting Assistant Professor at Harvard Medical School and Visiting Scientist at Massachusetts Institute of Technology. My research involves identifying cerebral edema progression through the analysis of novel biomarkers and machine learning methods. I was Chief Resident of Education during my final year of residency at Washington University School of Medicine, Resident of the Year as determined by the Medical School Class of 2016, and recipient of the Enhanced Leadership Award by the American Academy of Neurology in 2016. I am dedicated to advising and mentoring trainees at all stages, and am happy to assist with sharing my experiences and insights as an early-stage clinical-investigator and to help young professionals advance and achieve their professional and personal goals.

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Project Mentor
  • Work / Life Integration Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

72 E. Concord Street
Boston MA 02118
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