Charlene Ong, MD, MPHS, is an Assistant Professor of Neurology and Neurosurgery at Chobanian and Avedisian School of Medicine (BUSM), and clinical Neurointensivist at Boston Medical Center (BMC), and a lecturer at Harvard Medical School. She received her undergraduate degree at University of Pennsylvania, her MD at Columbia University and her Master's in Population Health Sciences at Washington University School of Medicine. Her research focuses on the development and validation of data-driven tools to support clinical decision making in patients with catastrophic neurologic injury including ischemic and hemorrhagic stroke, traumatic brain injury and anoxic brain injury. She receives support from the National Institute of Health through a K-award, and has also received foundational support from the American Brain Foundation, Philips-MIT, Peter-Paul Career Development Committee and Boston University Center for Translational Science Institute. Through machine learning methods, understudied physiologic biomarkers, and dynamic multimodal risk prediction methods, she aims to reduce morbidity and optimize treatment decision making in patients with acute neurologic disease.
Diversity, Equity, Inclusion and Accessibility
I firmly believe that fostering an environment which invigorates students and trainees from a variety of backgrounds, including those who are underrepresented in STEM, improves our science and humanity.
2019-Pres Mentorship of students from races/ethnicities underrepresented in STEM
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Neurosurgery
Visiting Scientist
Massachusetts Institute of Technology
This tab shows grant data from BMC Sponsored Research. It includes:
- Grant title
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- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from BU Sponsored Research. It includes:
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data that did not automatically get imported into Profiles
from BU or BMC sources.
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from the Boston VA. We are only showing grant title, and only for people in the role of PI.
Electrooculography and EEG Signal in Cardiac Arrest Patients in Intensive Care Units09/01/2023 - 08/31/2024 (Key Person / Mentor)
PI:
Cameron HillAmerican Academy of Neurology
Electrooculography signatures of arousal recovery after cardiac arrest04/01/2023 - 03/31/2026 (PI)
American Heart Association/AHA
Dynamic Risk Prediction of Life-Threatening Mass Effect After Ischemic Stroke04/01/2021 - 03/31/2026 (PI)
National Institute of Neurological Disorders and Stroke/NIH/DHHS1K23NS116033-01A1
Race / Ethnicity and Control of Hypertension after Intracerebral Hemorrhage01/01/2021 - 11/30/2022 (Multi-PI)
PI:
Charlene J. Ong, MD, MPHSMassachusetts General Hospital American Heart Assoc
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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Greige T, Tao BS, Dangayach NS, Gilmore EJ, O'Hana Nobleza C, Hinson HE, Chou SH, Jha RM, Wahlster S, Gebrewold MA, Lele AV, Ong CJ. Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey. Neurocrit Care. 2024 Jul 31.View Related Profiles. PMID: 39085504
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Ong CJ, Huang Q, Kim ISY, Pohlmann J, Chatzidakis S, Brush B, Zhang Y, Du Y, Malinger LA, Benjamin EJ, Dupuis J, Greer DM, Smirnakis SM, Trinquart L. Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke. Neurocrit Care. 2024 Jul 02.View Related Profiles. PMID: 38955931
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Abdalkader M, Nguyen TN, Sahoo A, Qureshi MM, Ong CJ, Klein P, Miller MI, Mian AZ, Kaesmacher J, Mujanovic A, Hu W, Chen HS, Setty BN. Contrast Staining in Noninfarcted Tissue after Endovascular Treatment of Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2024 Jun 07; 45(6):701-707.View Related Profiles. PMID: 38697792; PMCID: PMC11288587; DOI: 10.3174/ajnr.A8222;
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Pohlmann JE, Kim ISY, Brush B, Sambhu KM, Conti L, Saglam H, Milos K, Yu L, Cronin MFM, Balogun O, Chatzidakis S, Zhang Y, Trinquart L, Huang Q, Smirnakis SM, Benjamin EJ, Dupuis J, Greer DM, Ong CJ. Association of large core middle cerebral artery stroke and hemorrhagic transformation with hospitalization outcomes. Sci Rep. 2024 May 01; 14(1):10008.View Related Profiles. PMID: 38693282; PMCID: PMC11063151; DOI: 10.1038/s41598-024-60635-0;
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Song JJ, Stafford RA, Pohlmann JE, Kim ISY, Cheekati M, Dennison S, Brush B, Chatzidakis S, Huang Q, Smirnakis SM, Gilmore EJ, Mohammed S, Abdalkader M, Benjamin EJ, Dupuis J, Greer DM, Ong CJ. Later Midline Shift Is Associated with Better Outcomes after Large Middle Cerebral Artery Stroke. Res Sq. 2024 Apr 18.View Related Profiles. PMID: 38699310; PMCID: PMC11065061; DOI: 10.21203/rs.3.rs-4189278/v1;
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Stafford R, Chatzidakis S, Kim ISY, Zhang Y, Rina A, Brush B, Mian A, Abdalkader M, Greer DM, Smirnakis SM, Feske SK, Dupuis J, Ong CJ. Follow-up ASPECTS improves prediction of potentially lethal malignant edema in patients with large middle cerebral artery stroke. J Neurointerv Surg. 2023 Dec 30.View Related Profiles. PMID: 38160055; PMCID: PMC11214636; DOI: 10.1136/jnis-2023-021145;
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Ong C, Huang Q, Kim I, Pohlmann J, Chatzidakis S, Brush B, Zhang Y, Du Y, Mallinger LA, Benjamin EJ, Dupuis J, Greer D, Smirnakis S, Trinquart L. Dynamic trajectories of life-threatening mass effect in patients with large middle cerebral artery stroke. Res Sq. 2023 Nov 20.View Related Profiles. PMID: 38045289; PMCID: PMC10690305; DOI: 10.21203/rs.3.rs-3594179/v1;
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Showing 10 of 38 results.
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Hingorani KS, Barnes E, Carneiro T, Sader E, Anand P, Ong CJ, Chung D, Daneshmand A, Suchdev K, Takahashi C, Greer D, Shulman JG, Aparicio HJ, Nguyen TN, Romero JR, AbdalKader M, Feske SK, Kimmel SD, Weinstein ZM, Fagan M, Dobrilovic N, Awtry E, Cervantes-Arslanian AM. Strokes in Patients With Injection Drug Use and Tricuspid Valve Endocarditis - A Case Series. Neurohospitalist. 2023 Jul; 13(3):272-277.View Related Profiles. PMID: 37441214; PMCID: PMC10334046; DOI: 10.1177/19418744231159460;
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Dupre AE, Cronin MFM, Schmugge S, Tate S, Wack A, Prescott BR, Li C, Auerbach S, Suchdev K, Al-Faraj A, He W, Cervantes-Arslanian AM, Abdennadher M, Saxena A, Lehan W, Russo M, Pugsley B, Greer D, Shin M, Ong CJ. A machine learning eye movement detection algorithm using electrooculography. Sleep. 2023 Apr 12; 46(4).View Related Profiles. PMID: 36255119; DOI: 10.1093/sleep/zsac254;
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Chan WP, Prescott BR, Barra ME, Chung DY, Kim IS, Saglam H, Hutch MR, Shin M, Zafar SF, Benjamin EJ, Smirnakis SM, Dupuis J, Greer DM, Ong CJ. Dexmedetomidine and Other Analgosedatives Alter Pupil Characteristics in Critically Ill Patients. Crit Care Explor. 2022 May; 4(5):e0691.View Related Profiles. PMID: 35783547; PMCID: PMC9243241; DOI: 10.1097/CCE.0000000000000691;
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Miller MI, Orfanoudaki A, Cronin M, Saglam H, So Yeon Kim I, Balogun O, Tzalidi M, Vasilopoulos K, Fanaropoulou G, Fanaropoulou NM, Kalin J, Hutch M, Prescott BR, Brush B, Benjamin EJ, Shin M, Mian A, Greer DM, Smirnakis SM, Ong CJ. Natural Language Processing of Radiology Reports to Detect Complications of Ischemic Stroke. Neurocrit Care. 2022 Aug; 37(Suppl 2):291-302.View Related Profiles. PMID: 35534660; PMCID: PMC9986939; DOI: 10.1007/s12028-022-01513-3;
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Cervantes-Arslanian AM, Venkata C, Anand P, Burns JD, Ong CJ, LeMahieu AM, Schulte PJ, Singh TD, Rabinstein AA, Deo N, Bansal V, Boman K, Domecq Garces JP, Lee Armaignac D, Christie AB, Melamed RR, Tarabichi Y, Cheruku SR, Khanna AK, Denson JL, Banner-Goodspeed VM, Anderson HL, Gajic O, Kumar VK, Walkey A, Kashyap R. Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic. Crit Care Explor. 2022 Apr; 4(4):e0686.View Related Profiles. PMID: 35492258; PMCID: PMC9042584; DOI: 10.1097/CCE.0000000000000686;
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Prescott BR, Saglam H, Duskin JA, Miller MI, Thakur AS, Gholap EA, Hutch MR, Smirnakis SM, Zafar SF, Dupuis J, Benjamin EJ, Greer DM, Ong CJ. Anisocoria and Poor Pupil Reactivity by Quantitative Pupillometry in Patients With Intracranial Pathology. Crit Care Med. 2022 02 01; 50(2):e143-e153.View Related Profiles. PMID: 34637415; PMCID: PMC8810747; DOI: 10.1097/CCM.0000000000005272;
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Arandela K, Samudrala S, Abdalkader M, Anand P, Daneshmand A, Dasenbrock H, Nguyen T, Ong C, Takahashi C, Shulman J, Babi MA, Sivakumar S, Shah N, Jain S, Anand S, Nobleza COS, Shekhar S, Venkatasubramanian C, Salahuddin H, Taqi MA, Nour HA, Nofar JB, Cervantes-Arslanian AM. Reversible Cerebral Vasoconstriction Syndrome in Patients with Coronavirus Disease: A Multicenter Case Series. J Stroke Cerebrovasc Dis. 2021 Dec; 30(12):106118.View Related Profiles. PMID: 34560378; PMCID: PMC8445803; DOI: 10.1016/j.jstrokecerebrovasdis.2021.106118;
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Sreekrishnan A, Ong CJ, Mahajan R, Prescott B, Smirnakis SM, Bevers MB, Feske SK, Snider SB. Subcortical Sparing Associated with Ambulatory Independence after Hemicraniectomy for Malignant Infarction. J Stroke Cerebrovasc Dis. 2021 Aug; 30(8):105850.View Related Profiles. PMID: 34000606
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Takahashi CE, Virmani D, Chung DY, Ong C, Cervantes-Arslanian AM. Blunt and Penetrating Severe Traumatic Brain Injury. Neurol Clin. 2021 05; 39(2):443-469.View Related Profiles. PMID: 33896528
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Abdalkader M, Samuelsen BT, Moore JM, Cervantes-Arslanian A, Ong CJ, Setty BN, Mian AZ, Nguyen TN. Ruptured Spinal Aneurysms: Diagnosis and Management Paradigms. World Neurosurg. 2021 02; 146:e368-e377.View Related Profiles. PMID: 33223127
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Nwajei F, Anand P, Abdalkader M, Andreu Arasa VC, Aparicio HJ, Behbahani S, Curiale G, Daneshmand A, Dasenbrock H, Mayo T, Mian A, Nguyen T, Ong C, Romero JR, Sakai O, Takahashi C, Cervantes-Arslanian AM. Cerebral Venous Sinus Thromboses in Patients with SARS-CoV-2 Infection: Three Cases and a Review of the Literature. J Stroke Cerebrovasc Dis. 2020 Dec; 29(12):105412.View Related Profiles. PMID: 33254367; PMCID: PMC7571902; DOI: 10.1016/j.jstrokecerebrovasdis.2020.105412;
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Anand P, Slama MCC, Kaku M, Ong C, Cervantes-Arslanian AM, Zhou L, David WS, Guidon AC. Comment on COVID-19 in patients with myasthenia gravis: Author response. Muscle Nerve. 2020 12; 62(6):E87-E88.View Related Profiles. PMID: 32954519
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Ong CJ, Orfanoudaki A, Zhang R, Caprasse FPM, Hutch M, Ma L, Fard D, Balogun O, Miller MI, Minnig M, Saglam H, Prescott B, Greer DM, Smirnakis S, Bertsimas D. Machine learning and natural language processing methods to identify ischemic stroke, acuity and location from radiology reports. PLoS One. 2020; 15(6):e0234908.View Related Profiles. PMID: 32559211; PMCID: PMC7304623; DOI: 10.1371/journal.pone.0234908;
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Ong CJ. Quantitative Pupillometry: A Prognostic Tool for Cardiac Arrest and Refractory Cardiogenic Shock Undergoing VA-ECMO Therapy. Chest. 2020 05; 157(5):1049-1050. PMID: 32386622
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Barra ME, Feske SK, Sylvester KW, Ong C, Culbreth SE, Krause P, Henderson GV, Rybak E. Fibrinogen Concentrate for the Treatment of Thrombolysis-Associated Hemorrhage in Adult Ischemic Stroke Patients. Clin Appl Thromb Hemost. 2020 Jan-Dec; 26:1076029620951867.View Related Profiles. PMID: 32946279; PMCID: PMC7502993; DOI: 10.1177/1076029620951867;
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Ong C, Hutch M, Smirnakis S. The Effect of Ambient Light Conditions on Quantitative Pupillometry. Neurocrit Care. 2019 04; 30(2):316-321. PMID: 30218349
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Ong C, Hutch M, Barra M, Kim A, Zafar S, Smirnakis S. Effects of Osmotic Therapy on Pupil Reactivity: Quantification Using Pupillometry in Critically Ill Neurologic Patients. Neurocrit Care. 2019 04; 30(2):307-315. PMID: 30298336
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Ong C. Response to "Letter to the Editor" by Couret et al. Neurocrit Care. 2019 04; 30(2):494. PMID: 30644038
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Ong CJ, Gluckstein J, Laurido-Soto O, Yan Y, Dhar R, Lee JM. Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score: A Risk Prediction Tool. Stroke. 2017 07; 48(7):1969-1972. PMID: 28487333; PMCID: PMC5487281; DOI: 10.1161/STROKEAHA.117.016733;
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Ong CJ, Dhand A, Diringer MN. Early Withdrawal Decision-Making in Patients with Coma After Cardiac Arrest: A Qualitative Study of Intensive Care Clinicians. Neurocrit Care. 2016 10; 25(2):258-65. PMID: 27112149; DOI: 10.1007/s12028-016-0275-5;
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Ong CJ, Yarbrough CK, Derdeyn CP. Response to Letter Regarding Article, "Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis". Stroke. 2015 Dec; 46(12):e259. PMID: 26534973; DOI: 10.1161/STROKEAHA.115.011727;
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Yarbrough CK, Ong CJ, Beyer AB, Lipsey K, Derdeyn CP. Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis. Stroke. 2015 Nov; 46(11):3177-83. PMID: 26396032; DOI: 10.1161/STROKEAHA.115.009847;
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Ong CJ, Al-Lozi M, Cimino PJ, Bucelli R. Peripheral nervous system hyperexcitability in VV2 sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Aug; 5(4):326-332. PMID: 29443232; PMCID: PMC5764474; DOI: 10.1212/CPJ.0000000000000160;
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Ong CJ. Tipping point: Head computed tomography and its impact on neurology training. Ann Neurol. 2015 Apr; 77(4):556-9. PMID: 25612080; DOI: 10.1002/ana.24363;
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Ong C, Patel K, Musiek E, Van Stavern G. Mystery case: a young woman with isolated upbeating nystagmus. Neurology. 2015 Jan 27; 84(4):e17-9. PMID: 25628435
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Ong C, Gilmore E, Claassen J, Foreman B, Mayer SA. Impact of prolonged periodic epileptiform discharges on coma prognosis. Neurocrit Care. 2012 Aug; 17(1):39-44. PMID: 22700361
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 2012 | 1 |
| 2015 | 5 |
| 2016 | 1 |
| 2017 | 1 |
| 2019 | 3 |
| 2020 | 8 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 6 |
| 2024 | 6 |
2020-2021 Boston University:
CTSI Pilot Grant
2020-2021 Boston University, Department of Neurology:
Simon Grinspoon Grant
2020-2022 Boston University:
KL2
2018 “Neurology on the Hill”:
American Academy of Neurology
2018-2019 Massachusetts Institute of Technology:
Philips-MIT Clinician Investigator Award
2018-2021 Boston University :
Peter Paul Young Investigator Award
2017-2018 American Brain Foundation:
American Brain Foundation Crowd-Sourcing Grant Award
2015 Washington University School of Medicine:
Chief Resident of Education
2015-2016 American Academy of Neurology:
Enhanced Leadership Award
2014 Washington University School of Medicine:
Irwin Levy Teaching Prize
2014 Washington University School of Medicine:
Resident of The Year
2012 Columbia University:
Herbert J. Bartelstone Award in Pharmacology
2002 University of Pennsylvania:
Benjamin Franklin Scholar
2002 Wharton School of Business:
Joseph Wharton Scholar
I am an Assistant Professor in the Department of Neurology and Neurocritical Care Physician at Boston University School of Medicine. I am also a Visiting Assistant Professor at Harvard Medical School and Visiting Scientist at Massachusetts Institute of Technology. My research involves identifying cerebral edema progression through the analysis of novel biomarkers and machine learning methods. I was Chief Resident of Education during my final year of residency at Washington University School of Medicine, Resident of the Year as determined by the Medical School Class of 2016, and recipient of the Enhanced Leadership Award by the American Academy of Neurology in 2016. I am dedicated to advising and mentoring trainees at all stages, and am happy to assist with sharing my experiences and insights as an early-stage clinical-investigator and to help young professionals advance and achieve their professional and personal goals.
Available to Mentor as: (Review Mentor Role Definitions):
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Advisor
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Career Mentor
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Project Mentor
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Work / Life Integration Mentor