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PhD, Oregon State University
MS, Chonbuk National University
BS, Chonbuk National University

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Research
Publications

BU Research

Targeting Transcriptional Co-repressor CoREST Complex in Melanoma
09/01/2017 - 05/31/2018 (PI)
NIH/National Cancer Institute
1R01CA212639-01A1

Epigenetic detection and chemoprevention of skin cancer
10/01/2015 - 06/30/2016 (Subcontract PI)
The Johns Hopkins University V Foundation

Melanoma Assays Based on NRP-2
05/01/2010 - 09/30/2015 (Co-Investigator)
PI: Rhoda Alani, MD
Laboratory Corporation of America

Development of Novel Markers for Melanoma Progression
10/01/2011 - 06/30/2012 (PI)
NIH/National Institutes of Health
7K01CA113779-07

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Eisenstein A, Panova IP, Chung HJ, Goldberg LJ, Zhang Q, Lazova R, Bhawan J, Busam KJ, Symanowski JT, Alani RM, Ryu B. Quantitative assessment of neuropilin-2 as a simple and sensitive diagnostic assay for spitzoid melanocytic lesions. Melanoma Res. 2018 Feb; 28(1):71-75.View Related Profiles.

Eisenstein, Anna
Ryu, Byungwoo
Bhawan, Jag
Goldberg, Lynne
Alani, Rhoda

PMID: 29227334; PMCID: PMC5805139; DOI: 10.1097/CMR.0000000000000416;

Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018 01 04; 9(1):53.View Related Profiles.

Ryu, Byungwoo
Kim, Edward
Wu, Muzhou
Alani, Rhoda

PMID: 29302039; PMCID: PMC5754352; DOI: 10.1038/s41467-017-02242-4;

Hsu MY, Yang MH, Schnegg CI, Hwang S, Ryu B, Alani RM. Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis. Lab Invest. 2017 Jun; 97(6):725-736.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 28165469; PMCID: PMC5446297; DOI: 10.1038/labinvest.2017.1;

Hwang S, Kim HE, Min M, Raghunathan R, Panova IP, Munshi R, Ryu B. Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma. J Invest Dermatol. 2015 Sep; 135(9):2283-91.View Related Profiles.

Ryu, Byungwoo
Raghunathan, Rekha

PMID: 25910030; PMCID: PMC4537358; DOI: 10.1038/jid.2015.160;

Rossi M, Tuck J, Kim OJ, Panova I, Symanowski JT, Mahalingam M, Riker AI, Alani RM, Ryu B. Neuropilin-2 gene expression correlates with malignant progression in cutaneous melanoma. Br J Dermatol. 2014 Aug; 171(2):403-8.View Related Profiles.

Ryu, Byungwoo
Mahalingam, Meera
Alani, Rhoda

PMID: 24359286; DOI: 10.1111/bjd.12801;

Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, Wei W, Cui R. MC1R is a potent regulator of PTEN after UV exposure in melanocytes. Mol Cell. 2013 Aug 22; 51(4):409-22.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda
Cui, Rutao
Lenna, Stefania

PMID: 23973372; PMCID: PMC3792490; DOI: 10.1016/j.molcel.2013.08.010;

Ryu B, Hwang S, Alani RM. MicroRNAs as an emerging target for melanoma therapy. J Invest Dermatol. 2013 May; 133(5):1137-9.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 23594536; DOI: 10.1038/jid.2012.505;

Yan G, Eller MS, Elm C, Larocca CA, Ryu B, Panova IP, Dancy BM, Bowers EM, Meyers D, Lareau L, Cole PA, Taverna SD, Alani RM. Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells. J Invest Dermatol. 2013 Oct; 133(10):2444-52.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 23698071; PMCID: PMC4380234; DOI: 10.1038/jid.2013.187;

Liu F, Cao J, Wu J, Sullivan K, Shen J, Ryu B, Xu Z, Wei W, Cui R. Stat3-targeted therapies overcome the acquired resistance to vemurafenib in melanomas. J Invest Dermatol. 2013 Aug; 133(8):2041-9.View Related Profiles.

Ryu, Byungwoo
Liu, Fang
Cui, Rutao

PMID: 23344460; DOI: 10.1038/jid.2013.32;

Ryu B, Moriarty WF, Stine MJ, DeLuca A, Kim DS, Meeker AK, Grills LD, Switzer RA, Eller MS, Alani RM. Global analysis of BRAFV600E target genes in human melanocytes identifies matrix metalloproteinase-1 as a critical mediator of melanoma growth. J Invest Dermatol. 2011 Jul; 131(7):1579-83.View Related Profiles.

Ryu, Byungwoo
Eller, Mark
Alani, Rhoda

PMID: 21451543; PMCID: PMC3116059; DOI: 10.1038/jid.2011.65;

Showing 10 of 33 results. Show More

Stine MJ, Wang CJ, Moriarty WF, Ryu B, Cheong R, Westra WH, Levchenko A, Alani RM. Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction. Cancer Res. 2011 Apr 1; 71(7):2433-44.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 21324919; PMCID: PMC3070809; DOI: 10.1158/0008-5472.CAN-10-1875;

Kim HE, Symanowski JT, Samlowski EE, Gonzales J, Ryu B. Quantitative measurement of circulating lymphoid-specific helicase (HELLS) gene transcript: a potential serum biomarker for melanoma metastasis. Pigment Cell Melanoma Res. 2010 Dec; 23(6):845-8. PMID: 20727106; PMCID: PMC3192016; DOI: 10.1111/j.1755-148X.2010.00753.x;

Cummings SD, Ryu B, Samuels MA, Yu X, Meeker AK, Healey MA, Alani RM. Id1 delays senescence of primary human melanocytes. Mol Carcinog. 2008 Sep; 47(9):653-9.View Related Profiles.

Ryu, Byungwoo
Healey, Megan
Alani, Rhoda

PMID: 18240291; PMCID: PMC4066980; DOI: 10.1002/mc.20422;

Ryu B, Kim DS, DeLuca AM, Healey MA, Dunlap S, Fackler MJ, Herman J, Alani RM. Id1 expression is transcriptionally regulated in radial growth phase melanomas. Int J Cancer. 2007 Oct 15; 121(8):1705-9.View Related Profiles.

Ryu, Byungwoo
Healey, Megan
Alani, Rhoda

PMID: 17565736

Ryu B, Kim DS, Deluca AM, Alani RM. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression. PLoS One. 2007; 2(7):e594.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 17611626; PMCID: PMC1895889; DOI: 10.1371/journal.pone.0000594;

Govindarajan B, Shah A, Cohen C, Arnold RS, Schechner J, Chung J, Mercurio AM, Alani R, Ryu B, Fan CY, Cuezva JM, Martinez M, Arbiser JL. Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB. J Biol Chem. 2005 Apr 8; 280(14):13936-43.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 15695519

Cunningham SC, Ryu B, Sohn TA, Kern SE. Nonspecific enhancement of gene expression by compounds identified in high-throughput cell-based screening. Biotechniques. 2004 Jul; 37(1):120-2. PMID: 15283209

Sikder H, Huso DL, Zhang H, Wang B, Ryu B, Hwang ST, Powell JD, Alani RM. Disruption of Id1 reveals major differences in angiogenesis between transplanted and autochthonous tumors. Cancer Cell. 2003 Oct; 4(4):291-9.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 14585356

Sikder HA, Devlin MK, Dunlap S, Ryu B, Alani RM. Id proteins in cell growth and tumorigenesis. Cancer Cell. 2003 Jun; 3(6):525-30.View Related Profiles.

Ryu, Byungwoo
Alani, Rhoda

PMID: 12842081

Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C, Walter K, Sato N, Parker A, Ashfaq R, Jaffee E, Ryu B, Jones J, Eshleman JR, Yeo CJ, Cameron JL, Kern SE, Hruban RH, Brown PO, Goggins M. Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol. 2003 Apr; 162(4):1151-62. PMID: 12651607; PMCID: PMC1851213

Ryu B, Kern SE. The essential similarity of TGFbeta and activin receptor transcriptional responses in cancer cells. Cancer Biol Ther. 2003 Mar-Apr; 2(2):164-70. PMID: 12750556

Ryu B, Jones J, Blades NJ, Parmigiani G, Hollingsworth MA, Hruban RH, Kern SE. Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression. Cancer Res. 2002 Feb 1; 62(3):819-26. PMID: 11830538

Iacobuzio-Donahue CA, Ryu B, Hruban RH, Kern SE. Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion. Am J Pathol. 2002 Jan; 160(1):91-9. PMID: 11786403; PMCID: PMC1867150

Argani P, Iacobuzio-Donahue C, Ryu B, Rosty C, Goggins M, Wilentz RE, Murugesan SR, Leach SD, Jaffee E, Yeo CJ, Cameron JL, Kern SE, Hruban RH. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res. 2001 Dec; 7(12):3862-8. PMID: 11751476

Argani P, Rosty C, Reiter RE, Wilentz RE, Murugesan SR, Leach SD, Ryu B, Skinner HG, Goggins M, Jaffee EM, Yeo CJ, Cameron JL, Kern SE, Hruban RH. Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma. Cancer Res. 2001 Jun 1; 61(11):4320-4. PMID: 11389052

Sohn TA, Su GH, Ryu B, Yeo CJ, Kern SE. High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells. Ann Surg. 2001 May; 233(5):696-703. PMID: 11323508; PMCID: PMC1421310

Ryu B, Jones J, Hollingsworth MA, Hruban RH, Kern SE. Invasion-specific genes in malignancy: serial analysis of gene expression comparisons of primary and passaged cancers. Cancer Res. 2001 Mar 1; 61(5):1833-8. PMID: 11280733

Ryu B, Song J, Sohn T, Hruban RH, Kern SE. Frequent germline deletion polymorphism of chromosomal region 8p12-p21 identified as a recurrent homozygous deletion in human tumors. Genomics. 2001 Feb 15; 72(1):108-12. PMID: 11247673

Fletcher TM, Ryu BW, Baumann CT, Warren BS, Fragoso G, John S, Hager GL. Structure and dynamic properties of a glucocorticoid receptor-induced chromatin transition. Mol Cell Biol. 2000 Sep; 20(17):6466-75. PMID: 10938123; PMCID: PMC86121

Su GH, Sohn TA, Ryu B, Kern SE. A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. Cancer Res. 2000 Jun 15; 60(12):3137-42. PMID: 10866300

Ilian MA, Sparrow BR, Ryu BW, Selivonchick DP, Schaup HW. Expression of hepatic pyruvate carboxylase mRNA in C57BL/6J Ah(b/b) and congenic Ah((d/d)) mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biochem Toxicol. 1996; 11(1):51-6. PMID: 8806052

Ryu BW, Roy S, Sparrow BR, Selivonchick DP, Schaup HW. Ah receptor involvement in mediation of pyruvate carboxylase levels and activity in mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biochem Toxicol. 1995 Apr; 10(2):103-9. PMID: 7562952

Sparrow BR, Thompson CS, Ryu BW, Selevonchick DP, Schaup HW. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induced alterations of pyruvate carboxylase levels and lactate dehydrogenase isozyme shifts in C57BL/6J male mice. J Biochem Toxicol. 1994 Dec; 9(6):329-35. PMID: 7891369

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

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