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PhD, Oregon State University
MS, Chonbuk National University





Targeting Transcriptional Co-repressor CoREST Complex in Melanoma
09/01/2017 - 05/31/2018 (PI)
NIH/National Cancer Institute
1R01CA212639-01A1

Epigenetic detection and chemoprevention of skin cancer
10/01/2015 - 06/30/2016 (Subcontract PI)
Johns Hopkins University V Foundation


Melanoma Assays Based on NRP-2
05/01/2010 - 09/30/2015 (Co-Investigator)
PI: Rhoda Alani, MD
Laboratory Corporation of America


Development of Novel Markers for Melanoma Progression
10/01/2011 - 06/30/2012 (PI)
NIH/National Institutes of Health
7K01CA113779-07



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Eisenstein A, Panova IP, Chung HJ, Goldberg LJ, Zhang Q, Lazova R, Bhawan J, Busam KJ, Symanowski JT, Alani RM, Ryu B. Quantitative assessment of neuropilin-2 as a simple and sensitive diagnostic assay for spitzoid melanocytic lesions. Melanoma Res. 2018 Feb; 28(1):71-75.View Related Profiles. PMID: 29227334; PMCID: PMC5805139; DOI: 10.1097/CMR.0000000000000416;
     
  2. Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018 01 04; 9(1):53.View Related Profiles. PMID: 29302039; PMCID: PMC5754352; DOI: 10.1038/s41467-017-02242-4;
     
  3. Hsu MY, Yang MH, Schnegg CI, Hwang S, Ryu B, Alani RM. Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis. Lab Invest. 2017 Jun; 97(6):725-736.View Related Profiles. PMID: 28165469; PMCID: PMC5446297; DOI: 10.1038/labinvest.2017.1;
     
  4. Hwang S, Kim HE, Min M, Raghunathan R, Panova IP, Munshi R, Ryu B. Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma. J Invest Dermatol. 2015 Sep; 135(9):2283-91.View Related Profiles. PMID: 25910030; PMCID: PMC4537358; DOI: 10.1038/jid.2015.160;
     
  5. Rossi M, Tuck J, Kim OJ, Panova I, Symanowski JT, Mahalingam M, Riker AI, Alani RM, Ryu B. Neuropilin-2 gene expression correlates with malignant progression in cutaneous melanoma. Br J Dermatol. 2014 Aug; 171(2):403-8.View Related Profiles. PMID: 24359286; DOI: 10.1111/bjd.12801;
     
  6. Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, Wei W, Cui R. MC1R is a potent regulator of PTEN after UV exposure in melanocytes. Mol Cell. 2013 Aug 22; 51(4):409-22.View Related Profiles. PMID: 23973372; PMCID: PMC3792490; DOI: 10.1016/j.molcel.2013.08.010;
     
  7. Ryu B, Hwang S, Alani RM. MicroRNAs as an emerging target for melanoma therapy. J Invest Dermatol. 2013 May; 133(5):1137-9.View Related Profiles. PMID: 23594536; DOI: 10.1038/jid.2012.505;
     
  8. Yan G, Eller MS, Elm C, Larocca CA, Ryu B, Panova IP, Dancy BM, Bowers EM, Meyers D, Lareau L, Cole PA, Taverna SD, Alani RM. Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells. J Invest Dermatol. 2013 Oct; 133(10):2444-52.View Related Profiles. PMID: 23698071; PMCID: PMC4380234; DOI: 10.1038/jid.2013.187;
     
  9. Liu F, Cao J, Wu J, Sullivan K, Shen J, Ryu B, Xu Z, Wei W, Cui R. Stat3-targeted therapies overcome the acquired resistance to vemurafenib in melanomas. J Invest Dermatol. 2013 Aug; 133(8):2041-9.View Related Profiles. PMID: 23344460; DOI: 10.1038/jid.2013.32;
     
  10. Ryu B, Moriarty WF, Stine MJ, DeLuca A, Kim DS, Meeker AK, Grills LD, Switzer RA, Eller MS, Alani RM. Global analysis of BRAFV600E target genes in human melanocytes identifies matrix metalloproteinase-1 as a critical mediator of melanoma growth. J Invest Dermatol. 2011 Jul; 131(7):1579-83.View Related Profiles. PMID: 21451543; PMCID: PMC3116059; DOI: 10.1038/jid.2011.65;
     
Showing 10 of 33 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.



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