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MD, McGill University
BSc, McGill University

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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Tso GJ, Yuen K, Martins S, Tu SW, Ashcraft M, Heidenreich P, Hoffman BB, Goldstein MK. Test Case Selection in Pre-Deployment Testing of Complex Clinical Decision Support Systems. AMIA Jt Summits Transl Sci Proc. 2016; 2016:240-9. PMID: 27570678; PMCID: PMC5001770

Zulman DM, Martins SB, Liu Y, Tu SW, Hoffman BB, Asch SM, Goldstein MK. Using a Clinical Knowledge Base to Assess Comorbidity Interrelatedness Among Patients with Multiple Chronic Conditions. AMIA Annu Symp Proc. 2015; 2015:1381-9. PMID: 26958279; PMCID: PMC4765555

Zulman DM, Asch SM, Martins SB, Kerr EA, Hoffman BB, Goldstein MK. Quality of care for patients with multiple chronic conditions: the role of comorbidity interrelatedness. J Gen Intern Med. 2014 Mar; 29(3):529-37. PMID: 24081443; PMCID: PMC3930789; DOI: 10.1007/s11606-013-2616-9;

Abiose AK, Aronow WS, Moreno H, Nair CK, Blaschke TF, Hoffman BB. Increased vascular alpha1-adrenergic sensitivity in patients with renal failure: receiving recombinant erythropoeitin. Am J Ther. 2007 Sep-Oct; 14(5):427-34. PMID: 17890929

Bosworth HB, Olsen MK, McCant F, Harrelson M, Gentry P, Rose C, Goldstein MK, Hoffman BB, Powers B, Oddone EZ. Hypertension Intervention Nurse Telemedicine Study (HINTS): testing a multifactorial tailored behavioral/educational and a medication management intervention for blood pressure control. Am Heart J. 2007 Jun; 153(6):918-24. PMID: 17540191

Martins SB, Lai S, Tu S, Shankar R, Hastings SN, Hoffman BB, Dipilla N, Goldstein MK. Offline testing of the ATHENA Hypertension decision support system knowledge base to improve the accuracy of recommendations. AMIA Annu Symp Proc. 2006; 539-43. PMID: 17238399; PMCID: PMC1839611

Lin ND, Martins SB, Chan AS, Coleman RW, Bosworth HB, Oddone EZ, Shankar RD, Musen MA, Hoffman BB, Goldstein MK. Identifying barriers to hypertension guideline adherence using clinician feedback at the point of care. AMIA Annu Symp Proc. 2006; 494-8. PMID: 17238390; PMCID: PMC1839712

Goldstein MK, Lavori P, Coleman R, Advani A, Hoffman BB. Improving adherence to guidelines for hypertension drug prescribing: cluster-randomized controlled trial of general versus patient-specific recommendations. Am J Manag Care. 2005 Nov; 11(11):677-85. PMID: 16268751

Chan AS, Shankar RD, Coleman RW, Matins SB, Hoffman BB, Goldstein MK. Leveraging point-of-care clinician feedback to study barriers to guideline adherence. AMIA Annu Symp Proc. 2005; 915. PMID: 16779202; PMCID: PMC1560728

Steinman MA, Fischer MA, Shlipak MG, Bosworth HB, Oddone EZ, Hoffman BB, Goldstein MK. Clinician awareness of adherence to hypertension guidelines. Am J Med. 2004 Nov 15; 117(10):747-54. PMID: 15541324

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Goldstein MK, Coleman RW, Tu SW, Shankar RD, O'Connor MJ, Musen MA, Martins SB, Lavori PW, Shlipak MG, Oddone E, Advani AA, Gholami P, Hoffman BB. Translating research into practice: organizational issues in implementing automated decision support for hypertension in three medical centers. J Am Med Inform Assoc. 2004 Sep-Oct; 11(5):368-76. PMID: 15187064

Davies MF, Tsui J, Flannery JA, Li X, DeLorey TM, Hoffman BB. Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology. 2004 Feb; 29(2):229-39. PMID: 14583739

Chan AS, Coleman RW, Martins SB, Advani A, Musen MA, Bosworth HB, Oddone EZ, Shlipak MG, Hoffman BB, Goldstein MK. Evaluating provider adherence in a trial of a guideline-based decision support system for hypertension. Stud Health Technol Inform. 2004; 107(Pt 1):125-9. PMID: 15360788

Davies MF, Tsui JY, Flannery JA, Li X, DeLorey TM, Hoffman BB. Augmentation of the noradrenergic system in alpha-2 adrenergic receptor deficient mice: anatomical changes associated with enhanced fear memory. Brain Res. 2003 Oct 03; 986(1-2):157-65. PMID: 12965240

Chen J, Hoffman BB, Isseroff RR. Beta-adrenergic receptor activation inhibits keratinocyte migration via a cyclic adenosine monophosphate-independent mechanism. J Invest Dermatol. 2002 Dec; 119(6):1261-8. PMID: 12485426

Hu ZW, Kerb R, Shi XY, Wei-Lavery T, Hoffman BB. Angiotensin II increases expression of cyclooxygenase-2: implications for the function of vascular smooth muscle cells. J Pharmacol Exp Ther. 2002 Nov; 303(2):563-73. PMID: 12388637

Szeto HC, Coleman RK, Gholami P, Hoffman BB, Goldstein MK. Accuracy of computerized outpatient diagnoses in a Veterans Affairs general medicine clinic. Am J Manag Care. 2002 Jan; 8(1):37-43. PMID: 11814171

Goldstein MK, Hoffman BB, Coleman RW, Tu SW, Shankar RD, O'Connor M, Martins S, Martins S, Advani A, Musen MA. Patient safety in guideline-based decision support for hypertension management: ATHENA DSS. Proc AMIA Symp. 2001; 214-8. PMID: 11825183

Chalon S, Moreno H, Benowitz NL, Hoffman BB, Blaschke TF. Nicotine impairs endothelium-dependent dilatation in human veins in vivo. Clin Pharmacol Ther. 2000 Apr; 67(4):391-7. PMID: 10801248

Hu JS, Durst M, Kerb R, Truong V, Ma JT, Khurgin E, Balaban D, Gingeras TR, Hoffman BB. Analysis of drug pharmacology towards predicting drug behavior by expression profiling using high-density oligonucleotide arrays. Ann N Y Acad Sci. 2000; 919:9-15. PMID: 11083092

Hoffman BB, Hu ZW. Alpha(1)-adrenoceptors (alpha(1)-AR) and vascular smooth muscle cell growth. Prostate Suppl. 2000; 9:29-33. PMID: 11056500

Goldstein MK, Hoffman BB, Coleman RW, Musen MA, Tu SW, Advani A, Shankar R, O'Connor M. Implementing clinical practice guidelines while taking account of changing evidence: ATHENA DSS, an easily modifiable decision-support system for managing hypertension in primary care. Proc AMIA Symp. 2000; 300-4. PMID: 11079893

Hu ZW, Hoffman BB. Nuclear run-on assays for measurement of adrenergic receptor transcription rate. Methods Mol Biol. 2000; 126:169-80. PMID: 10685409

Duchna HW, Guilleminault C, Stoohs RA, Faul JL, Moreno H, Hoffman BB, Blaschke TF. Vascular reactivity in obstructive sleep apnea syndrome. Am J Respir Crit Care Med. 2000 Jan; 161(1):187-91. PMID: 10619819

Tangphao O, Chalon S, Moreno HJ, Abiose AK, Blaschke TF, Hoffman BB. Heparin-induced vasodilation in human hand veins. Clin Pharmacol Ther. 1999 Sep; 66(3):232-8. PMID: 10511058

Hu ZW, Shi XY, Lin RZ, Chen J, Hoffman BB. alpha1-Adrenergic receptor stimulation of mitogenesis in human vascular smooth muscle cells: role of tyrosine protein kinases and calcium in activation of mitogen-activated protein kinase. J Pharmacol Exp Ther. 1999 Jul; 290(1):28-37. PMID: 10381756

Chen J, Lin R, Hu ZW, Hoffman BB. alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+. J Pharmacol Exp Ther. 1999 Jun; 289(3):1376-84. PMID: 10336529

Tangphao O, Grossmann M, Chalon S, Hoffman BB, Blaschke TF. Pharmacokinetics of intravenous and oral L-arginine in normal volunteers. Br J Clin Pharmacol. 1999 Mar; 47(3):261-6. PMID: 10215749

Chalon S, Moreno H, Hoffman BB, Blaschke TF. Angiotensin-converting enzyme inhibition improves venous endothelial dysfunction in chronic smokers. Clin Pharmacol Ther. 1999 Mar; 65(3):295-303. PMID: 10096262

Tangphao O, Chalon S, Moreno H, Hoffman BB, Blaschke TF. Pharmacokinetics of L-arginine during chronic administration to patients with hypercholesterolaemia. Clin Sci (Lond). 1999 Feb; 96(2):199-207. PMID: 9918901

Hu ZW, Shi XY, Lin RZ, Hoffman BB. Contrasting signaling pathways of alpha1A- and alpha1B-adrenergic receptor subtype activation of phosphatidylinositol 3-kinase and Ras in transfected NIH3T3 cells. Mol Endocrinol. 1999 Jan; 13(1):3-14. PMID: 9892008

Chalon S, Tejura B, Moreno H, Urae A, Blaschke TF, Hoffman BB. Role of nitric oxide in isoprenaline and sodium nitroprusside-induced relaxation in human hand veins. Br J Clin Pharmacol. 1999 Jan; 47(1):91-8. PMID: 10073745

Tangphao O, Chalon S, Coulston AM, Moreno H, Chan JR, Cooke JP, Hoffman BB, Blaschke TF. L-arginine and nitric oxide-related compounds in plasma: comparison of normal and arginine-free diets in a 24-h crossover study. Vasc Med. 1999; 4(1):27-32. PMID: 10355867

Chalon S, Bedarida GV, Moreno H, Tejura B, Urae A, Hoffman BB, Blaschke TF. Inhibition of angiotensin-converting enzyme in human hand veins. Clin Pharmacol Ther. 1999 Jan; 65(1):58-65. PMID: 9951431

Lin RZ, Chen J, Hu ZW, Hoffman BB. Phosphorylation of the cAMP response element-binding protein and activation of transcription by alpha1 adrenergic receptors. J Biol Chem. 1998 Nov 06; 273(45):30033-8. PMID: 9792725

Moreno H, Chalon S, Urae A, Tangphao O, Abiose AK, Hoffman BB, Blaschke TF. Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation. Am J Physiol. 1998 09; 275(3):H1040-5. PMID: 9724311

Hu ZW, Shi XY, Hoffman BB. Doxazosin inhibits proliferation and migration of human vascular smooth-muscle cells independent of alpha1-adrenergic receptor antagonism. J Cardiovasc Pharmacol. 1998 Jun; 31(6):833-9. PMID: 9641467

Lin RZ, Hu ZW, Chin JH, Hoffman BB. Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts. J Biol Chem. 1997 Dec 05; 272(49):31196-202. PMID: 9388274

Abiose AK, Grossmann M, Tangphao O, Hoffman BB, Blaschke TF. Chloroquine-induced venodilation in human hand veins. Clin Pharmacol Ther. 1997 Jun; 61(6):677-83. PMID: 9209251

Grossmann M, Abiose A, Tangphao O, Blaschke TF, Hoffman BB. Morphine-induced venodilation in humans. Clin Pharmacol Ther. 1996 Nov; 60(5):554-60. PMID: 8941028

Hu ZW, Shi XY, Hoffman BB. Insulin and insulin-like growth factor I differentially induce alpha1-adrenergic receptor subtype expression in rat vascular smooth muscle cells. J Clin Invest. 1996 Oct 15; 98(8):1826-34. PMID: 8878434

Chin JH, Okazaki M, Frazier JS, Hu ZW, Hoffman BB. Impaired cAMP-mediated gene expression and decreased cAMP response element binding protein in senescent cells. Am J Physiol. 1996 Jul; 271(1 Pt 1):C362-71. PMID: 8760066

Miller JW, Hu ZW, Okazaki M, Fujinaga M, Hoffman BB. Expression of alpha 1 adrenergic receptor subtype mRNAs in the rat cardiovascular system with aging. Mech Ageing Dev. 1996 Jun 07; 87(2):75-89. PMID: 8783191

Chin JH, Okazaki M, Hu ZW, Miller JW, Hoffman BB. Activation of heat shock protein (hsp)70 and proto-oncogene expression by alpha1 adrenergic agonist in rat aorta with age. J Clin Invest. 1996 May 15; 97(10):2316-23. PMID: 8636412

Hu ZW, Shi XY, Lin RZ, Hoffman BB. Alpha1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. Role in mitogenesis. J Biol Chem. 1996 Apr 12; 271(15):8977-82. PMID: 8621543

Chin JH, Hiremath AN, Hoffman BB. cAMP signaling mechanisms with aging in rats. Mech Ageing Dev. 1996 Jan 05; 86(1):11-26. PMID: 8866733

Okazaki M, Hu ZW, Fujinaga M, Hoffman BB. Alpha 1 adrenergic receptor activation of proto-oncogene expression in arterial smooth muscle: regulation by nitric oxide and vascular injury. Recept Signal Transduct. 1996; 6(3-4):165-78. PMID: 9259051

Thomas JM, Frazier JS, Hu ZW, Hoffman BB. Phosphorylation of cyclic AMP response element-binding protein and induction of c-fos gene expression on withdrawal from chronic treatment with carbachol in NG108-15 cells. Mol Pharmacol. 1995 Oct; 48(4):593-600. PMID: 7476883

Fujinaga M, Hu ZW, Okazaki M, Baden JM, Hoffman BB. Expression of mRNA for alpha1-adrenoceptor subtypes at the beginning of neurulation in rat embryos. Toxicol In Vitro. 1995 Oct; 9(5):601-6. PMID: 20650135

Bedarida G, Bushell E, Blaschke TF, Hoffman BB. H1- and H2-histamine receptor-mediated vasodilation varies with aging in humans. Clin Pharmacol Ther. 1995 Jul; 58(1):73-80. PMID: 7628185

Shilo L, Chin JH, Azhar S, Hoffman BB. Prolonged infusion of epinephrine down-regulates expression of the fatty acid synthase gene in adipocytes. Endocrine. 1995 Jun; 3(6):439-44. PMID: 21153248

Hu ZW, Shi XY, Okazaki M, Hoffman BB. Angiotensin II induces transcription and expression of alpha 1-adrenergic receptors in vascular smooth muscle cells. Am J Physiol. 1995 Mar; 268(3 Pt 2):H1006-14. PMID: 7900855

Ford GA, Dachman WD, Blaschke TF, Hoffman BB. Effect of aging on beta 2-adrenergic receptor-stimulated flux of K+, PO4, FFA, and glycerol in human forearms. J Appl Physiol (1985). 1995 Jan; 78(1):172-8. PMID: 7713808

Okazaki M, Hu ZW, Fujinaga M, Hoffman BB. Alpha 1 adrenergic receptor-induced c-fos gene expression in rat aorta and cultured vascular smooth muscle cells. J Clin Invest. 1994 Jul; 94(1):210-8. PMID: 8040263

Fujinaga M, Hoffman BB, Baden JM. Receptor subtype and intracellular signal transduction pathway associated with situs inversus induced by alpha 1 adrenergic stimulation in rat embryos. Dev Biol. 1994 Apr; 162(2):558-67. PMID: 8150214

Dachman WD, Bedarida G, Blaschke TF, Hoffman BB. Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes. J Allergy Clin Immunol. 1994 Mar; 93(3):606-14. PMID: 8151062

Bedarida GV, Kim D, Blaschke TF, Hoffman BB. Characterization of an inhibitor of nitric oxide synthase in human-hand veins. Horm Metab Res. 1994 Feb; 26(2):109-12. PMID: 7515369

Hu ZW, Miller JW, Hoffman BB. Induction of enhanced release of endothelium-derived relaxing factor after prolonged exposure to alpha-adrenergic agonists: role in desensitization of smooth muscle contraction. J Cardiovasc Pharmacol. 1994 Feb; 23(2):337-43. PMID: 7511767

Sakaue M, Hoffman BB. Effects of cell density and conditioned medium on alpha 2A adrenergic receptor density and messenger RNA abundance in HT-29 cells. Life Sci. 1994; 54(23):1785-91. PMID: 8196492

Bedarida G, Kim D, Blaschke TF, Hoffman BB. Venodilation in Raynaud's disease. Lancet. 1993 Dec 11; 342(8885):1451-4. PMID: 7902481

Hu ZW, Hoffman BB. Cycloheximide induces the alpha 1B adrenergic receptor gene by activation of transcription in DDT1 MF-2 smooth muscle cells. Mol Pharmacol. 1993 Dec; 44(6):1105-12. PMID: 8264546

Bedarida GV, Bushell E, Haefeli WE, Blaschke TF, Hoffman BB. Responsiveness to bradykinin in veins of hypercholesterolemic humans. Circulation. 1993 Dec; 88(6):2754-61. PMID: 8252688

Ford GA, Blaschke TF, Wiswell R, Hoffman BB. Effect of aging on changes in plasma potassium during exercise. J Gerontol. 1993 Jul; 48(4):M140-5. PMID: 8315226

Haefeli WE, Srivastava N, Kelsey KT, Wiencke JK, Hoffman BB, Blaschke TF. Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness. Clin Pharmacol Ther. 1993 Apr; 53(4):463-8. PMID: 8477563

Hu ZW, Shi XY, Sakaue M, Hoffman BB. Prolonged activation of protein kinase C induces transcription and expression of the alpha 1B adrenergic receptor gene in DDT1 MF-2 cells. J Biol Chem. 1993 Feb 15; 268(5):3610-5. PMID: 8381435

Haefeli WE, Bargetzi MJ, Starnes HF, Blaschke TF, Hoffman BB. Evidence for activation of the sympathetic nervous system by recombinant human interleukin-1 beta in humans. J Immunother Emphasis Tumor Immunol. 1993 Feb; 13(2):136-40. PMID: 8318499

Dachman WD, Ford GA, Blaschke TF, Hoffman BB. Mechanism of bradykinin-induced venodilation in humans. J Cardiovasc Pharmacol. 1993 Feb; 21(2):241-8. PMID: 7679158

Haefeli WE, Srivastava N, Kongpatanakul S, Blaschke TF, Hoffman BB. Lack of role of endothelium-derived relaxing factor in effects of alpha-adrenergic agonists in cutaneous veins in humans. Am J Physiol. 1993 Feb; 264(2 Pt 2):H364-9. PMID: 8095374

Thomas JM, Hoffman BB. Buprenorphine prevents and reverses the expression of chronic etorphine-induced sensitization of adenylyl cyclase in SK-N-SH human neuroblastoma cells. J Pharmacol Exp Ther. 1993 Jan; 264(1):368-74. PMID: 8380866

Haefeli WE, Gumbleton M, Benet LZ, Hoffman BB, Blaschke TF. Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins. Clin Pharmacol Ther. 1992 Dec; 52(6):590-6. PMID: 1458768

Vincent J, Kongpatanakul S, Blaschke TF, Hoffman BB. Desensitization of nitrate-induced venodilation: reversal with oral N-acetylcysteine in humans. J Cardiovasc Pharmacol. 1992 Dec; 20(6):907-12. PMID: 1282593

Hu Z, Azhar S, Hoffman BB. Prolonged activation of alpha 1 adrenoceptors induces down-regulation of protein kinase C in vascular smooth muscle. J Cardiovasc Pharmacol. 1992 Dec; 20(6):982-9. PMID: 1282603

Vincent J, Dachman W, Blaschke TF, Hoffman BB. Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans. J Clin Invest. 1992 Nov; 90(5):1763-8. PMID: 1358918

Dachman WD, Ford GA, Hoffman BB, Blaschke TF. Bradykinin-induced venodilation is not impaired with aging in humans. J Gerontol. 1992 Sep; 47(5):M166-70. PMID: 1512432

Skinner MH, Futterman A, Morrissette D, Thompson LW, Hoffman BB, Blaschke TF. Atenolol compared with nifedipine: effect on cognitive function and mood in elderly hypertensive patients. Ann Intern Med. 1992 Apr 15; 116(8):615-23. PMID: 1546860

Costa EM, Hoffman BB, Loew GH. Assessment of delta-opioid receptor activation by a series of peptides in cultured cells. Int J Pept Protein Res. 1992 Mar; 39(3):245-9. PMID: 1328097

Vincent J, Blaschke TF, Hoffman BB. Desensitization of beta-adrenoceptor- and prostaglandin E1 receptor-mediated human vascular smooth muscle relaxation. J Cardiovasc Pharmacol. 1992 Mar; 19(3):447-52. PMID: 1378128

Hu ZW, Honda K, Murad F, Hoffman BB. Prolonged exposure to catecholamines enhances sensitivity of smooth muscle relaxation induced by sodium nitroprusside and atriopeptin. J Pharmacol Exp Ther. 1992 Feb; 260(2):756-61. PMID: 1346644

Eichler HG, Blaschke TF, Kraemer FB, Ford GA, Blöchl-Daum B, Hoffman BB. Responsiveness of superficial hand veins to alpha-adrenoceptor agonists in insulin-dependent diabetic patients. Clin Sci (Lond). 1992 Feb; 82(2):163-8. PMID: 1347259

Ford GA, Hoffman BB, Vestal RE, Blaschke TF. Age-related changes in adenosine and beta-adrenoceptor responsiveness of vascular smooth muscle in man. Br J Clin Pharmacol. 1992 Jan; 33(1):83-7. PMID: 1311596

Ford GA, Hoffman BB, Blaschke TF. Beta adrenergically mediated cardiac chronotropic and vascular smooth muscle responses during propranolol therapy and withdrawal in young and elderly persons. J Gerontol. 1992 Jan; 47(1):M22-6. PMID: 1730849

Vincent J, Blaschke TF, Hoffman BB. Vascular reactivity to phenylephrine and angiotensin II: comparison of direct venous and systemic vascular responses. Clin Pharmacol Ther. 1992 Jan; 51(1):68-75. PMID: 1732078

Sakaue M, Hoffman BB. Glucocorticoids induce transcription and expression of the alpha 1B adrenergic receptor gene in DTT1 MF-2 smooth muscle cells. J Clin Invest. 1991 Aug; 88(2):385-9. PMID: 1650792

Ford GA, Katzir D, Blaschke TF, Hoffman BB. Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension. Clin Pharmacol Ther. 1991 Aug; 50(2):192-8. PMID: 1651200

Hiremath AN, Hu ZW, Hoffman BB. Desensitization of alpha-adrenergic receptor-mediated smooth muscle contraction: role of the endothelium. J Cardiovasc Pharmacol. 1991 Jul; 18(1):151-7. PMID: 1719284

Chin JH, Hoffman BB. Beta-adrenergic responsiveness in cultured vascular smooth muscle cells and fibroblasts: effect of age. Mech Ageing Dev. 1991 Mar; 57(3):259-73. PMID: 1647473

Eichler HG, Blaschke TF, Hoffman BB. Decreased responsiveness of superficial hand veins to phenylephrine in black normotensive males. J Cardiovasc Pharmacol. 1990 Aug; 16(2):177-81. PMID: 1697371

Hu ZW, Billingham M, Tuck M, Hoffman BB. Captopril improves hypertension and cardiomyopathy in rats with pheochromocytoma. Hypertension. 1990 Feb; 15(2):210-5. PMID: 2154406

Ford GA, Hoffman BB, Blaschke TF. Effect of temazepam on blood pressure regulation in healthy elderly subjects. Br J Clin Pharmacol. 1990 Jan; 29(1):61-7. PMID: 1967533

Hiremath AN, Hoffman BB, Blaschke TF. Responsiveness of peripheral veins to transdermal and sublingual nitroglycerin in healthy male volunteers. J Cardiovasc Pharmacol. 1989 Oct; 14(4):534-41. PMID: 2478766

Deisher TA, Mankani S, Hoffman BB. Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age. J Pharmacol Exp Ther. 1989 Jun; 249(3):812-9. PMID: 2543812

Eichler HG, Eichler I, Lewiston N, Blaschke TF, Hoffman BB. Responsiveness of superficial hand veins to adrenergic stimuli in patients with cystic fibrosis. Clin Sci (Lond). 1989 Mar; 76(3):283-7. PMID: 2924520

Hiremath AN, Pershe RA, Hoffman BB, Blaschke TF. Comparison of age-related changes in prostaglandin E1 and beta-adrenergic responsiveness of vascular smooth muscle in adult males. J Gerontol. 1989 Jan; 44(1):M13-7. PMID: 2536054

Eichler HG, Ford GA, Blaschke TF, Swislocki A, Hoffman BB. Responsiveness of superficial hand veins to phenylephrine in essential hypertension. Alpha adrenergic blockade during prazosin therapy. J Clin Invest. 1989 Jan; 83(1):108-12. PMID: 2562959

Ford GA, Eichler HG, Hoffman BB, Blaschke TF. Venous responsiveness to atrial natriuretic factor in man. Br J Clin Pharmacol. 1988 Dec; 26(6):797-9. PMID: 2977285

Reaven GM, Ho H, Hoffman BB. Attenuation of fructose-induced hypertension in rats by exercise training. Hypertension. 1988 Aug; 12(2):129-32. PMID: 3410522

Prokocimer PG, Maze M, Vickery RG, Hoffman BB. Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma. Endocrinology. 1988 Jul; 123(1):528-33. PMID: 2838264

Rosenbaum JS, Azhar S, Hoffman BB. Alpha 1 adrenergic receptor mediated polyphosphoinositide breakdown in DDT1-MF2 cells. Lack of evidence of desensitization after prolonged exposure to epinephrine. Biochem Pharmacol. 1987 Dec 15; 36(24):4335-40. PMID: 2825723

Eichler HG, Hiremath A, Katzir D, Blaschke TF, Hoffman BB. Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans. Clin Pharmacol Ther. 1987 Nov; 42(5):521-4. PMID: 3119271

Pan HY, Hoffman BB, Pershe RA, Blaschke TF. Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man. J Pharmacol Exp Ther. 1986 Dec; 239(3):802-7. PMID: 3025419

Tsujimoto G, Lee CH, Hoffman BB. Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation. J Pharmacol Exp Ther. 1986 Nov; 239(2):411-5. PMID: 2430092

Hoffman BB, Chang H, Dall'Aglio E, Reaven GM. Desensitization of adenosine receptor-mediated inhibition of lipolysis. The mechanism involves the development of enhanced cyclic adenosine monophosphate accumulation in tolerant adipocytes. J Clin Invest. 1986 Jul; 78(1):185-90. PMID: 3013937

Tsujimoto A, Tsujimoto G, Azhar S, Hoffman BB. Altered responsiveness to alpha- and beta-adrenoceptor stimulation in hepatocytes cultured in defined medium. Biochem Pharmacol. 1986 Apr 15; 35(8):1400-4. PMID: 2870718

Reitz AB, Avery MA, Rosenkranz RP, Verlander MS, Melmon KL, Hoffman BB, Akita Y, Castagnoli N, Goodman M. Conjugates of catecholamines. 6. Synthesis and beta-adrenergic activity of N-(hydroxyalkyl)catecholamine derivatives. J Med Chem. 1985 May; 28(5):642-7. PMID: 2859373

Reitz AB, Sonveaux E, Rosenkranz RP, Verlander MS, Melmon KL, Hoffman BB, Akita Y, Castagnoli N, Goodman M. Conjugates of catecholamines. 5. Synthesis and beta-adrenergic activity of N-(aminoalkyl)norepinephrine derivatives. J Med Chem. 1985 May; 28(5):634-42. PMID: 2859372

Hoffman BB, Chang H, Farahbakhsh ZT, Reaven GM. Age-related decrement in hormone-stimulated lipolysis. Am J Physiol. 1984 Dec; 247(6 Pt 1):E772-7. PMID: 6150643

Hoffman BB, Lavin TN, Lefkowitz RJ, Ruffolo RR. Alpha adrenergic receptor subtypes in rabbit uterus: mediation of myometrial contraction and regulation by estrogens. J Pharmacol Exp Ther. 1981 Nov; 219(2):290-5. PMID: 6270302

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