Dr. Huber completed his undergraduate studies at the University of California Santa Cruz and earned a PhD degree in Biophysics at the University of California San Francisco. He earned his MD from the Harvard-MIT Health Science and Technology program. He completed residency training in Anatomic Pathology and fellowship training in Neuropathology at the University of Washington. Dr. Huber is an Assistant Professor of Neurology at Boston University and is the director of the PTSD Brain Bank at the Jamaica Plain Veterans Administration. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy and Framingham Heart Study. Dr. Huber’s research interests center on the relationship between neurotrauma and neurodegenerative diseases, with a primary focus on the blood-brain barrier and neuroinflammation. Much of his current work centers on astrocytic injury in repetitive neurotrauma and the accumulation of tau pathology. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the PTSD brain bank. Dr Huber is a member of the Society for Neuroscience, the College of American Pathologists, the American Society of Clinical Pathologists, and the International Society for Biological and Environmental Repositories.
Framingham Heart Study
Director of PTSD Brain Bank
Boston University School of Medicine
Alzheimer's Disease Center
Chronic Traumatic Encephalopathy (CTE) Center
VA Boston Healthcare System
2013 Eagles Club:
2002 Thomas D. Cabot Fellowship
2002 Office of Enrichment Programs Research Scholarship
1995 Phi Beta Kappa:
Investigating the response of CNS neurons to electric and magnetic stimulation
06/15/2019 - 05/31/2023 (Subcontract PI)Massachusetts General Hospital NIH NINDS5R01NS110575-02
Publications listed below are automatically derived from MEDLINE/PubMed and other
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Showing 10 of 48 results.
Chancellor KB, Chancellor SE, Duke-Cohan JE, Huber BR, Stein TD, Alvarez VE, Okaty BW, Dymecki SM, McKee AC. Altered oligodendroglia and astroglia in chronic traumatic encephalopathy. Acta Neuropathol. 2021 Aug; 142(2):295-321.View Related Profiles. PMID: 34019156
Cherry JD, Esnault CD, Baucom ZH, Tripodis Y, Huber BR, Alvarez VE, Stein TD, Dickson DW, McKee AC. Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer's disease. Acta Neuropathol Commun. 2021 05 12; 9(1):86.View Related Profiles. PMID: 33980303; PMCID: PMC8114683; DOI: 10.1186/s40478-021-01189-4;
Mez J, Alosco ML, Daneshvar DH, Saltiel N, Baucom Z, Abdolmohammadi B, Uretsky M, Nicks R, Martin BM, Palmisano JN, Nowinski CJ, Montenigro P, Solomon TM, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Goldstein LE, Katz DI, Cantu RC, Kowall NW, Tripodis Y, Huber BR, Stein TD, Stern RA, McKee AC. Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathology. Alzheimers Dement. 2021 Apr 07.View Related Profiles. PMID: 33826224
Girgenti MJ, Wang J, Ji D, Cruz DA, Stein MB, Gelernter J, Young KA, Huber BR, Williamson DE, Friedman MJ, Krystal JH, Zhao H, Duman RS. Transcriptomic organization of the human brain in post-traumatic stress disorder. Nat Neurosci. 2021 01; 24(1):24-33. PMID: 33349712
Cherry JD, Meng G, Daley S, Xia W, Svirsky S, Alvarez VE, Nicks R, Pothast M, Kelley H, Huber B, Tripodis Y, Alosco ML, Mez J, McKee AC, Stein TD. CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy. J Neuroinflammation. 2020 Dec 05; 17(1):370.View Related Profiles. PMID: 33278887; PMCID: PMC7718711; DOI: 10.1186/s12974-020-02036-4;
Yang K, Stein TD, Huber BR, Sartor EA, Rachlin JR, Mahalingam M. Glioblastoma and malignant melanoma: Serendipitous or anticipated association? Neuropathology. 2021 Feb; 41(1):65-71.View Related Profiles. PMID: 33103282
Wolf EJ, Chen CD, Zhao X, Zhou Z, Morrison FG, Daskalakis NP, Stone A, Schichman S, Grenier JG, Fein-Schaffer D, Huber BR, Abraham CR, Miller MW, Logue MW. Klotho, PTSD, and advanced epigenetic age in cortical tissue. Neuropsychopharmacology. 2021 03; 46(4):721-730.View Related Profiles. PMID: 33096543; PMCID: PMC8027437; DOI: 10.1038/s41386-020-00884-5;
Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 12; 140(6):851-862.View Related Profiles. PMID: 32939646; PMCID: PMC7669574; DOI: 10.1007/s00401-020-02206-x;
Mez J, Daneshvar DH, Alosco ML, Alvarez VE, Huber BR, Stein TD, McKee AC. Reply to "Chronic Traumatic Encephalopathy and Primary Age-Related Tauopathy". Ann Neurol. 2020 11; 88(5):1052-1053.View Related Profiles. PMID: 32754941
Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 10; 140(4):495-512.View Related Profiles. PMID: 32778942; PMCID: PMC7914059; DOI: 10.1007/s00401-020-02197-9;
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