Bang-Bon Koo, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Anatomy & Neurobiology

PhD, Hanyang University
MS, Hanyang University
BS, Hanyang University

Dr.Koo's research interests span the areas of neuroimaging, particularly the development of multi-modal magnetic resonance imaging (MRI) and analysis methods. Neuroimaging commonly aims to identify difference between healthy and unhealthy brains in a quantitative way. However, due to the complexity of the human brain, it is extremely difficult to analyze early stage or slow disease progressions from visually inspecting the image. Dr.Koo's work focuses on developing novel imaging protocols and mapping methods with better sensitivities on monitoring neurological and functional changes in the brain. Dr.Koo also serves as an imaging core director at National Emerging Infectious Disease Laboratories (NEIDL). The goal is to develop multimodal imaging protocol that allows in-vivo monitoring on different stages of tissue inflammatory/immune responses.

Boston University
National Emerging Infectious Disease Lab

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Prefrontal-cingulate functional networks in aging monkeys: neural circuit substrates of cognitive aging
09/01/2023 - 08/31/2026 (Multi-PI)
PI: Bang-Bon Koo, PhD
NIH/National Institute on Aging

Identification of objective brain imaging biomarkers for Gulf War Illness (GWI): exposure- & symptom-specific markers, GW subtypes, and longitudinal patterns
07/01/2022 - 06/30/2025 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Validating Novel Brain Imaging Biomarkers for classifying mild Traumatic Brain Injury and subsequent risks of Alzheimer's Disease in Gulf War Veterans
05/01/2020 - 04/30/2024 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Dietary quality, cognitive decline and brain health in Puerto Rican adults
09/15/2017 - 05/31/2023 (Subcontract PI)
University of Massachusetts, Lowell NIH NIA

Computer aided decoding of brain-immune interactions in Gulf War Illness (GWI): a joint embedding on brain connectomic and immunogenetic markers
09/01/2017 - 08/31/2021 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Computer aided decoding of brain-immune interactions in Gulf War Illness (GWI): a joint embedding on brain connectomic and immunogenetic markers
09/01/2017 - 08/31/2020 (PI)
Department of Defense/Army Medical Research Acquisition Activity


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Naeser MA, Martin PI, Ho MD, Krengel MH, Bogdanova Y, Knight JA, Hamblin MR, Fedoruk AE, Poole LG, Cheng C, Koo B. Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy. J Alzheimers Dis Rep. 2023; 7(1):77-105.View Related Profiles. PMID: 36777329; PMCID: PMC9912826; DOI: 10.3233/ADR-220022;
  2. Koo BB, Guan Y. Author Response: Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2023 Jan 17; 100(3):164-165. PMID: 36646472
  3. Guan Y, Ebrahimzadeh SA, Cheng CH, Chen W, Leung T, Bigornia S, Palacios N, Garelnabi MO, Scott T, Bhadelia R, Tucker KL, Koo BB. Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2022 Apr 12; 98(15):e1534-e1544. PMID: 35354581; PMCID: PMC9012269; DOI: 10.1212/WNL.0000000000200120;
  4. Gonuguntla V, Yang E, Guan Y, Koo BB, Kim JH. Brain signatures based on structural MRI: Classification for MCI, PMCI, and AD. Hum Brain Mapp. 2022 Jun 15; 43(9):2845-2860. PMID: 35289025; PMCID: PMC9120560; DOI: 10.1002/hbm.25820;
  5. Yang E, Kim CK, Guan Y, Koo BB, Kim JH. 3D multi-scale residual fully convolutional neural network for segmentation of extremely large-sized kidney tumor. Comput Methods Programs Biomed. 2022 Mar; 215:106616. PMID: 35026623
  6. Cheng CH, Alshelh Z, Guan Y, Sullivan K, Loggia ML, Koo BB. Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness. Brain Behav Immun Health. 2021 Dec; 18:100364.View Related Profiles. PMID: 34693367; PMCID: PMC8515380; DOI: 10.1016/j.bbih.2021.100364;
  7. Keating D, Zundel CG, Abreu M, Krengel M, Aenlle K, Nichols MD, Toomey R, Chao LL, Golier J, Abdullah L, Quinn E, Heeren T, Groh JR, Koo BB, Killiany R, Loggia ML, Younger J, Baraniuk J, Janulewicz P, Ajama J, Quay M, Baas PW, Qiang L, Conboy L, Kokkotou E, O'Callaghan JP, Steele L, Klimas N, Sullivan K. Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community. Life Sci. 2021 Nov 01; 284:119903.View Related Profiles. PMID: 34453948; PMCID: PMC9643044; DOI: 10.1016/j.lfs.2021.119903;
  8. Steele L, Klimas N, Krengel M, Quinn E, Toomey R, Little D, Abreu M, Aenlle K, Killiany R, Koo BB, Janulewicz P, Heeren T, Clark AN, Ajama J, Cirillo J, Buentello G, Lerma V, Coller JK, Sullivan K. Brain-Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of 1990-1991 Gulf War Veterans in the Gulf War Illness Consortium (GWIC) Multisite Case-Control Study. Brain Sci. 2021 Aug 26; 11(9).View Related Profiles. PMID: 34573153; PMCID: PMC8467437; DOI: 10.3390/brainsci11091132;
  9. Farris CW, Killiany RJ, O'Donoghue E, Koo BB, Wainford RD, Moss MB, Rosene DL, Moore TL. The relationship of age and hypertension with cognition and gray matter cerebral blood volume in a rhesus monkey model of human aging. Behav Neurosci. 2021 Oct; 135(5):680-692.View Related Profiles. PMID: 34197136
  10. Bhattacharya B, Xiao S, Chatterjee S, Urbanowski M, Ordonez A, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor J, Ivanov AR, Yan BS, Kobzik L, Koo BB, Jain S, Bishai W, Kramnik I. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. J Clin Invest. 2021 02 01; 131(3).View Related Profiles. PMID: 33301427; PMCID: PMC7843230; DOI: 10.1172/JCI130319;
Showing 10 of 51 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 20 distinct years, with a maximum of 7 publications in 2017


2023 Boston University School of Medicine: Marion and Henri Gendron, DSc, Faculty Award
2009 Trainee Award, Human Brain Mapping (funded by NIH)
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

- Biomedical Imaging
- Brain Mapping / Neuroimaging
- Multimodal Imaging: MRI, Optical, CT
- Image Processing
- Imaging Feature Development

Available to Mentor as: (Review Mentor Role Definitions):
  • Diversity Mentor
  • Project Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

620 Albany St
Boston MA 02118
Google Map

Koo's Networks
Click the "See All" links for more information and interactive visualizations
Media Mentions
Similar People
Same Department