Angela Ho | Profiles RNS

Angela Ho, PhD

Associate Professor

Boston University College of Arts and Sciences

Dept of Biology

PhD, Mount Sinai School of Medicine

Websites

	Biology
	Neuroscience
	Center for Systems Neuroscience
	Graduate Medical Sciences

Associate Professor
Boston University College of Arts and Sciences
Neuroscience

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Associate Chair
Boston University College of Arts and Sciences
Biology

BU Research
NIH RePORTER Research

Role of apoE-apoER2 interactions in CNS neurons
07/01/2018 - 06/30/2023 (Multi-PI)
PI: Angela Ho, PhD
NIH/National Institute on Aging
5R01AG059762-03

Mint Adaptor Proteins in APP Binding and Processing
02/01/2014 - 01/31/2021 (PI)
NIH/National Institute on Aging
5R01AG044499-05

Role of FOXR1 in Mammalian Brain Development
07/01/2015 - 06/30/2018 (Multi-PI)
PI: Angela Ho, PhD
NIH/National Institute of General Medical Sciences
5R21GM114629-02

Role of CLASP2 in Neurodevelopment
12/01/2013 - 11/30/2016 (Multi-PI)
PI: Angela Ho, PhD
NIH/National Institute of Mental Health
5R21MH100581-02

PHYSIOLOGICAL FUNCTION OF APP PROTIENS IN THE ADULT MAMMALIAN BRAIN
10/01/2009 - 03/31/2013 (PI)
Alzheimer's Association

Title

Yr	Title	Project-Sub Proj	Pubs
2018	Mint Adaptor Proteins in APP Binding and Processing	5R01AG044499-05	2
2017	Mint Adaptor Proteins in APP Binding and Processing	5R01AG044499-04	2
2016	Role of FOXR1 in Mammalian Brain Development	5R21GM114629-02
2016	Mint Adaptor Proteins in APP Binding and Processing	5R01AG044499-03	2
2015	Role of FOXR1 in Mammalian Brain Development	1R21GM114629-01
2015	Mint Adaptor Proteins in APP Binding and Processing	5R01AG044499-02	2
2015	Role of CLASP2 in Neurodevelopment	5R21MH100581-02	1
2014	Mint Adaptor Proteins in APP Binding and Processing	1R01AG044499-01A1	2
2014	Role of CLASP2 in Neurodevelopment	1R21MH100581-01A1	1
2010	Mints: Adaptor Proteins Coupling APP of Alzheimer's Disease to the Synapse	5K01AG027311-07	6

Showing 10 of 19 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Lee SH, Kang J, Ho A, Watanabe H, Bolshakov VY, Shen J. APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival. Neuron. 2020 11 25; 108(4):676-690.e8. PMID: 32891188

Sullivan SE, Dillon GM, Sullivan JM, Ho A. Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ß generation. J Biol Chem. 2014 May 30; 289(22):15374-83. PMID: 24742670

Peritore CS, Ho A, Yamamoto BK, Schaus SE. Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells. Neuroreport. 2012 Dec 5; 23(17):989-94.View Related Profiles.

Ho, Angela
Schaus, Scott

PMID: 23114623; DOI: 10.1097/WNR.0b013e32835a4ea4;

Beffert U, Dillon GM, Sullivan JM, Stuart CE, Gilbert JP, Kambouris JA, Ho A. Microtubule plus-end tracking protein CLASP2 regulates neuronal polarity and synaptic function. J Neurosci. 2012 Oct 03; 32(40):13906-16. PMID: 23035100

Chaufty J, Sullivan SE, Ho A. Intracellular amyloid precursor protein sorting and amyloid-ß secretion are regulated by Src-mediated phosphorylation of Mint2. J Neurosci. 2012 Jul 11; 32(28):9613-25. PMID: 22787047

Matos MF, Xu Y, Dulubova I, Otwinowski Z, Richardson JM, Tomchick DR, Rizo J, Ho A. Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3802-7. PMID: 22355143

Zhang D, Zhang C, Ho A, Kirkwood A, Südhof TC, Shen J. Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction. J Neurochem. 2010 Dec; 115(5):1215-21. PMID: 20854432

Mukherjee K, Yang X, Gerber SH, Kwon HB, Ho A, Castillo PE, Liu X, Südhof TC. Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6504-9. PMID: 20332206

Ho A, Liu X, Südhof TC. Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease. J Neurosci. 2008 Dec 31; 28(53):14392-400. PMID: 19118172

Atasoy D, Schoch S, Ho A, Nadasy KA, Liu X, Zhang W, Mukherjee K, Nosyreva ED, Fernandez-Chacon R, Missler M, Kavalali ET, Südhof TC. Deletion of CASK in mice is lethal and impairs synaptic function. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2525-30. PMID: 17287346

Showing 10 of 21 results. Show More

Ho A, Morishita W, Atasoy D, Liu X, Tabuchi K, Hammer RE, Malenka RC, Südhof TC. Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family. J Neurosci. 2006 Dec 13; 26(50):13089-101. PMID: 17167098

Dulubova I, Ho A, Huryeva I, Südhof TC, Rizo J. Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein. Biochemistry. 2004 Aug 03; 43(30):9583-8. PMID: 15274612

Ho A, Südhof TC. Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2548-53. PMID: 14983046

Ho A, Morishita W, Hammer RE, Malenka RC, Sudhof TC. A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):1409-14. PMID: 12547917

Sugita S, Ho A, Südhof TC. NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern. Neuroscience. 2002; 112(1):51-63. PMID: 12044471; DOI: 10.1016/s0306-4522(02)00063-5;

Ho A, Blum M. Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease. J Neurosci. 1998 Aug 01; 18(15):5614-29. PMID: 9671653

Gore AC, Yeo TT, Ho A, Roberts JL. Post-transcriptional regulation of the gonadotropin-releasing hormone gene in GT1-7 cells. J Neuroendocrinol. 1997 Apr; 9(4):271-7. PMID: 9147290; DOI: 10.1046/j.1365-2826.1997.00579.x;

Ho A, Gore AC, Weickert CS, Blum M. Glutamate regulation of GDNF gene expression in the striatum and primary striatal astrocytes. Neuroreport. 1995 Jul 10; 6(10):1454-8. PMID: 7488747; DOI: 10.1097/00001756-199507100-00023;

Gore AC, Ho A, Roberts JL. Translational efficiency of gonadotropin-releasing hormone messenger ribonucleic acid is negatively regulated by phorbol ester in GT1-7 cells. Endocrinology. 1995 Apr; 136(4):1620-5. PMID: 7895672; DOI: 10.1210/endo.136.4.7895672;

Dalmau J, Graus F, Cheung NK, Rosenblum MK, Ho A, Cañete A, Delattre JY, Thompson SJ, Posner JB. Major histocompatibility proteins, anti-Hu antibodies, and paraneoplastic encephalomyelitis in neuroblastoma and small cell lung cancer. Cancer. 1995 Jan 01; 75(1):99-109. PMID: 7804984; DOI: 10.1002/1097-0142(19950101)75:1<99::aid-cncr2820750117>3.0.co;2-i;

Jean WC, Dalmau J, Ho A, Posner JB. Analysis of the IgG subclass distribution and inflammatory infiltrates in patients with anti-Hu-associated paraneoplastic encephalomyelitis. Neurology. 1994 Jan; 44(1):140-7. PMID: 8290049; DOI: 10.1212/wnl.44.1.140;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 4 publications in 2012

Bar chart showing 21 publications over 14 distinct years, with a maximum of 4 publications in 2012

Year	Publications
1994	1
1995	3
1997	1
1998	1
2002	1
2003	1
2004	2
2006	1
2007	1
2008	1
2010	2
2012	4
2014	1
2020	1

Contact for Mentoring:

617.353.2432

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Schaus, Scott

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