Andrea Havasi, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Nephrology

MD, Semmelweis University



Andrea Havasi, M.D. is an Assistant Professor of Medicine at Boston University. She is board certified in Internal Medicine and Nephrology. As a recipient of the National Kidney Foundation Research Fellow Award, she undertook research training at BMC investigating the cytoprotective mechanisms of heat shock proteins in ischemic renal cell injury and apoptosis. She joined the Renal Section Faculty in 2008, and continues basic and translational research in the area of renal cell injury and proteinuric kidney diseases using cell culture and animal models. She is the recipient of the American Heart Association Scientist Development Grant and NIH K08 award. She also has a special clinical and research interest in onco-nephrology and amyloidosis, and is a faculty in BU’s Amyloidosis Center. Dr. Havasi is a Co-Director of BU’s Mitochondria Affinity Research Collaborative, and Director of Nephrology Fellowship Program’s Onco-nephrology / Amyloidosis Pathway. Her clinical roles include attending time on the consult and dialysis/transplant services and weekly outpatient clinics (amyloidosis, chronic kidney disease, hemodialysis and peritoneal dialysis clinics).
Current research interest:
1. Amyloid renal disease
Mechanism of amyloid fibril formation and deposition in the kidney.
2. Proteinuria and renal fibrosis
Mechanisms of proteinuria induced tubular damage, interstitial fibrosis and inflammation in progressive kidney diseases. Proteinuria is associated with progressive chronic kidney disease. It is well known that exposure of proximal tubular epithelial cells to large amounts of albumin leads to the development of tubular atrophy and fibrosis. However, the possible pathogenic role of albumin in this process has not been fully elucidated. Development of new therapeutic tools to prevent or slow the progression of proteinuric chronic kidney disease requires clear understanding of the effect of proteinuria on tubular cell function.

Active Staff Hospital Privileges
Boston Medical Center
Medicine





Proteinuria Causes Progressive Kidney Disease by Impairing Autophagy
07/15/2011 - 10/31/2016 (PI)
NIH-NIDDK
5K08 DK090143-05

Proteinuria causes progressive kidney disease by impairing autophagy
01/01/2011 - 02/28/2014 (PI)
American Heart Assoc

HSP70 As a Cytoprotective Protein: Interaction with the ACL2 Family
07/01/2005 - 06/30/2008 (PI)
National Kidney Fdtn


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Wang Z, Salih E, Igwebuike C, Mulhern R, Bonegio RG, Havasi A, Borkan SC. Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic AKI. J Am Soc Nephrol. 2019 Jan; 30(1):50-62.View Related Profiles. PMID: 30573638.
     
  2. Angel-Korman A, Stern L, Sarosiek S, Sloan JM, Doros G, Sanchorawala V, Havasi A. Long-term outcome of kidney transplantation in AL amyloidosis. Kidney Int. 2019 Feb; 95(2):405-411.View Related Profiles. PMID: 30580886.
     
  3. Havasi A, Doros G, Sanchorawala V. Predictive value of the new renal response criteria in AL amyloidosis treated with high dose melphalan and stem cell transplantation. Am J Hematol. 2018 May; 93(5):E129-E132.View Related Profiles. PMID: 29430701.
     
  4. Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death". Mol Cell Biol. 2017 10 01; 37(19).View Related Profiles. PMID: 28899998.
     
  5. Batalini F, Econimo L, Quillen K, Sloan JM, Sarosiek S, Brauneis D, Havasi A, Stern L, Dember LM, Sanchorawala V. High-Dose Melphalan and Stem Cell Transplantation in Patients on Dialysis Due to Immunoglobulin Light-Chain Amyloidosis and Monoclonal Immunoglobulin Deposition Disease. Biol Blood Marrow Transplant. 2018 01; 24(1):127-132.View Related Profiles. PMID: 28865972.
     
  6. Prokaeva T, Akar H, Spencer B, Havasi A, Cui H, O'Hara CJ, Gursky O, Leszyk J, Steffen M, Browning S, Rosenberg A, Connors LH. Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant. Kidney Int Rep. 2017 Nov; 2(6):1223-1232.View Related Profiles. PMID: 29270531.
     
  7. Havasi A, Lu W, Cohen HT, Beck L, Wang Z, Igwebuike C, Borkan SC. Blocking peptides and molecular mimicry as treatment for kidney disease. Am J Physiol Renal Physiol. 2017 Jun 01; 312(6):F1016-F1025.View Related Profiles. PMID: 27654896; DOI: 10.1152/ajprenal.00601.2015;.
     
  8. Menn-Josephy H, Lee CS, Nolin A, Christov M, Rybin DV, Weinberg JM, Henderson J, Bonegio R, Havasi A. Renal Interstitial Fibrosis: An Imperfect Predictor of Kidney Disease Progression in Some Patient Cohorts. Am J Nephrol. 2016; 44(4):289-299.View Related Profiles. PMID: 27626625.
     
  9. Nolin AC, Mulhern RM, Panchenko MV, Pisarek-Horowitz A, Wang Z, Shirihai O, Borkan SC, Havasi A. Proteinuria causes dysfunctional autophagy in the proximal tubule. Am J Physiol Renal Physiol. 2016 Dec 01; 311(6):F1271-F1279.View Related Profiles. PMID: 27582098; DOI: 10.1152/ajprenal.00125.2016;.
     
  10. Havasi A, Stern L, Lo S, Sun F, Sanchorawala V. Validation of new renal staging system in AL amyloidosis treated with high dose melphalan and stem cell transplantation. Am J Hematol. 2016 10; 91(10):E458-60.View Related Profiles. PMID: 27356490; DOI: 10.1002/ajh.24464;.
     
Showing 10 of 30 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 30 publications over 15 distinct years, with a maximum of 5 publications in 2016

YearPublications
20011
20042
20051
20081
20092
20101
20113
20122
20132
20142
20152
20165
20173
20182
20191
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Proteinuric renal disease

Available to Mentor as: (Review Mentor Role Definitions):
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Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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