PhD, Brown University
MS, University of Connecticut

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Quinn JA, Graeber CT, Frackelton AR, Kim M, Schwarzbauer JE, Filardo EJ. Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30. Mol Endocrinol. 2009 Jul; 23(7):1052-64. PMID: 19342448; PMCID: PMC2703602; DOI: 10.1210/me.2008-0262;.
  2. Grossman SR, Lyle S, Resnick MB, Sabo E, Lis RT, Rosinha E, Liu Q, Hsieh CC, Bhat G, Frackelton AR, Hafer LJ. p66 Shc tumor levels show a strong prognostic correlation with disease outcome in stage IIA colon cancer. Clin Cancer Res. 2007 Oct 1; 13(19):5798-804. PMID: 17908971.
  3. Wanebo HJ, Frackelton AR, Hafer LJ, Bagdasaryan R, Lis R, Sabo E, Resnick MB. Shc test as a strong prognostic indicator of disease outcome in early stage gastric cancer. J Clin Oncol. 2006 Jun 20; 24(18_suppl):10090.View Related Profiles. PMID: 27954030.
  4. Frackelton AR, Lu L, Davol PA, Bagdasaryan R, Hafer LJ, Sgroi DC. p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy. Breast Cancer Res. 2006; 8(6):R73. PMID: 17196107; PMCID: PMC1797038.
  5. Davol PA, Bagdasaryan R, Elfenbein GJ, Maizel AL, Frackelton AR. Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer. Cancer Res. 2003 Oct 15; 63(20):6772-83. PMID: 14583473.
  6. Filardo EJ, Quinn JA, Frackelton AR, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol. 2002 Jan; 16(1):70-84. PMID: 11773440.
  7. Boney CM, Sekimoto H, Gruppuso PA, Frackelton AR. Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells. Cell Growth Differ. 2001 Jul; 12(7):379-86. PMID: 11457735.
  8. Filardo EJ, Quinn JA, Bland KI, Frackelton AR. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol. 2000 Oct; 14(10):1649-60. PMID: 11043579.
  9. Boney CM, Gruppuso PA, Faris RA, Frackelton AR. The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes. Mol Endocrinol. 2000 Jun; 14(6):805-13. PMID: 10847583.
  10. Davol PA, Garza S, Frackelton AR. Combining suramin and a chimeric toxin directed to basic fibroblast growth factor receptors increases therapeutic efficacy against human melanoma in an animal model. Cancer. 1999 Nov 1; 86(9):1733-41. PMID: 10547546.
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