Lillian E.C. McMahon, MD
Associate Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology Section

MD, Federal University of Para



Expertise includes: Sickle cell anemia; Sickle cell disease; Hemoglobin C disease; Hemoglobinopathies.

Associate Professor
Boston University School of Medicine
Department of Pediatrics
Pediatric Subspecialties (Pediatric Hematology) Section

Active Staff Privileges
Boston Medical Center
Department of Medicine
Hematology & Medical Oncology Section



A 5-year, prospective, non-interventional, multi-center registry in Sickle Cell Disease patients
02/09/2010 - 12/31/2017 (PI)
Novartis Pharmaceuticals Corporation

Assessing the effectiveness of anti-sickling agents for sickle hemoglobin and red blood cells
02/01/2016 - 01/31/2017 (Co-PI)
PI: Elizabeth S. Klings, MD
General Hospital Corp d/b/a Massachusetts General Hospital

Blood Samples, Blood Laboratory Test Results and Questionnaire Data from Sickle Cell Disease Blood Donors Collected under an IRB Approved Protocol with Signed Informed Consent
12/06/2013 - 12/31/2016 (PI)
Biogen Idec

A Phase ll, Multicenter, Randomized, Placebo-Controlled, Double-Blind, 12-Month Study to Assess Safety and Efficacy of SeIG1 with or without Hydroxyurea Therapy in Sickle Cell Disease Patients with Si
08/30/2013 - 08/31/2016 (PI)
Selexys Pharmaceuticals Corporation

Neutrophil Elastase as a Biomarker for Neutrophil-mediated Pathbiology in Sickle Cell Disease
12/21/2015 - 06/20/2016 (Co-PI)
PI: Elizabeth S. Klings, MD
Children's Hospital, Oakland Bayer HealthCare

A Double-Blind, Randomized, Multicenter Study of Prasugrel Compared to Placebo in Adult Patients with Sickle Cell Disease
01/01/2011 - 12/31/2014 (PI)
Eli Lilly and Company

A Phase III, Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study of L-Glutamine Therapy for Sickle Cell Anemia and Sickle B0- Thalassemia
04/01/2010 - 06/30/2014 (PI)
Emmaus Medical, Inc

A DOUBLE-BLIND, RANDOMIZED, MULTICENTER STUDY OF PRASUGREL COMPARED TO PLACEBO IN ADULT PATIENTS WITH
01/01/2011 - 12/31/2013 (PI)
Eli Lilly and Company

A Phase 2 randomized, double-blind, placebo-controlled study of the efficacy, safety, and pharmacokinetics of GMI-1070, a pan-selectin inhibitor, in subjects hospitalized for sickle cell vaso-occ
04/01/2010 - 03/31/2012 (PI)
Glycomimetrics, Inc.

A Phase II, Multicenter, Twelve-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Range-Finding Study of the Efficacy and Safety of ICA-17043 with or without Hydorxyurea Therapy in Patients with Sickle Cell Anemia
01/17/2002 - 01/16/2003 (PI)
IcaGen, Inc.

Showing 10 of 11 results. Show All Results

B0401016: Phase1B, Randomized, Double-Blind (Sponsor Open), Placebo-Controlled Study to Evaluate…
05/20/2015 - 05/31/2017 (PI)
Pfizer, Inc

Boston Sickle Cell Research consortium - IMPROVE STUDY CLINICAL TRIAL
09/01/2009 - 03/31/2011 (PI)
New England Res Inst NIH-NHLBI

PROACTIVE
12/17/2008 - 03/31/2011 (PI)
New England Res Inst NIH-NHLBI

Boston Sickle Cell Research Consortium
05/01/2006 - 03/31/2011 (PI)
NIH-NHLBI
5U10 HL083771-05

Comprehensive Sickle Cell Cent
01/01/1992 - 03/31/2004 (PI)
NIH-NHLBI
5 P60 HL15157-30

Sickle Cell Transition Program
09/30/1998 - 05/30/2002 (PI)
Brigham & Women's

Nitrite Oxide By Inhalation
02/02/1999 - 02/02/2000 (PI)
INO Therapeutics(IKARIA)



Yr Title Project-Sub Proj Pubs
2008 Boston Sickle Cell Research Consortium 5U10HL083771-03
2007 ARGININE SUPPLEMENTATION IN SICKLE CELL ANEMIA-PHYSIOLOGICAL AND PROPHYLATIC 2M01RR000533-39-8167 429
2007 NEUROPSYCHOLOGICAL DYSFUNCTION AND NEUROIMAGING ABNORMALITIES IN SCD 2M01RR000533-39-8168 429
2007 Boston Sickle Cell Research Consortium 5U10HL083771-02
2007 CORE--Patient Services Core 5U54HL070819-05-9003 78
2006 Boston Sickle Cell Research Consortium 1U10HL083771-01
2006 ARGININE SUPPLEMENTATION IN SICKLE CELL ANEMIA-PHYSIOLOGICAL AND PROPHYLATIC 5M01RR000533-38-5616 429
2006 NEUROPSYCHOLOGICAL DYSFUNCTION AND NEUROIMAGING ABNROMALITIES IN SCD 5M01RR000533-38-5618 429
2006 CORE--Patient Services Core 5U54HL070819-04-9003 78
2005 CORE--Patient Services Core 5U54HL070819-03-9003 78
Showing 10 of 42 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Wun T, Soulieres D, Frelinger AL, Krishnamurti L, Novelli EM, Kutlar A, Ataga KI, Knupp CL, McMahon LE, Strouse JJ, Zhou C, Heath LE, Nwachuku CE, Jakubowski JA, Riesmeyer JS, Winters KJ. A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease. J Hematol Oncol. 2013; 6:17. PMID: 23414938; PMCID: PMC3585853; DOI: 10.1186/1756-8722-6-17;.
  2. Styles L, Wager CG, Labotka RJ, Smith-Whitley K, Thompson AA, Lane PA, McMahon LE, Miller R, Roseff SD, Iyer RV, Hsu LL, Castro OL, Ataga KI, Onyekwere O, Okam M, Bellevue R, Miller ST. Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: results of a feasibility study (PROACTIVE). Br J Haematol. 2012 Jun; 157(5):627-36. PMID: 22463614; PMCID: PMC3349768; DOI: 10.1111/j.1365-2141.2012.09105.x;.
  3. McMahon L, Tamary H, Askin M, Adams-Graves P, Eberhardt RT, Sutton M, Wright EC, Castaneda SA, Faller DV, Perrine SP. A randomized phase II trial of Arginine Butyrate with standard local therapy in refractory sickle cell leg ulcers. Br J Haematol. 2010 Dec; 151(5):516-24.View Related Profiles. PMID: 20955402; DOI: 10.1111/j.1365-2141.2010.08395.x;.
  4. Dampier C, Lieff S, LeBeau P, Rhee S, McMurray M, Rogers Z, Smith-Whitley K, Wang W. Health-related quality of life in children with sickle cell disease: a report from the Comprehensive Sickle Cell Centers Clinical Trial Consortium. Pediatr Blood Cancer. 2010 Sep; 55(3):485-94. PMID: 20658620; PMCID: PMC2911637; DOI: 10.1002/pbc.22497;.
  5. Vichinsky EP, Neumayr LD, Gold JI, Weiner MW, Rule RR, Truran D, Kasten J, Eggleston B, Kesler K, McMahon L, Orringer EP, Harrington T, Kalinyak K, De Castro LM, Kutlar A, Rutherford CJ, Johnson C, Bessman JD, Jordan LB, Armstrong FD. Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia. JAMA. 2010 May 12; 303(18):1823-31. PMID: 20460621; PMCID: PMC2892214; DOI: 10.1001/jama.2010.562;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 3 publications in 2010

YearPublications
20103
20121
20131
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Hemoglobin C disease
Hemoglobinopathies
Sickle cell anemia
Sickle cell disease

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