Keith Tornheim, PhD
Associate Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, Brandeis University



Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Boston Medical Center




Phosphofructokinase-M and Adipose Mass
04/01/2005 - 03/31/2008 (PI)
Boston Medical Center NIH NIDDK

Phosphofructokinase and Oscillatory Insulin Secretion
03/01/2002 - 02/28/2006 (PI)
Juvenile Diabetes Foundation International

Metabolic Oscillations and Insulin Secretion
07/01/1997 - 06/30/2002 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5 R01 DK53064 04




Yr Title Project-Sub Proj Pubs
2000 METABOLIC OSCILLATIONS AND INSULIN SECRETION 5R01DK053064-04 12
1999 METABOLIC OSCILLATIONS AND INSULIN SECRETION 5R01DK053064-03 12
1998 METABOLIC OSCILLATIONS AND INSULIN SECRETION 5R01DK053064-02 12
1997 METABOLIC OSCILLATIONS AND INSULIN SECRETION 1R01DK053064-01 12
1994 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 5R01DK031559-10 21
1993 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 5R01DK031559-09 21
1992 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 5R01DK031559-08 21
1991 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 2R01DK031559-07A3 21
1988 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 5R01DK031559-06 21
1987 OSCILLATIONS AND THE CONTROL OF GLYCOLYSIS 5R01DK031559-05 21
Showing 10 of 12 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Martínez-Costa OH, Sánchez V, Lázaro A, Hernández ED, Tornheim K, Aragón JJ. Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase. Biochem J. 2012 Jul 15; 445(2):213-8. PMID: 22530721; DOI: 10.1042/BJ20120173;.
  2. Haller JF, Smith C, Liu D, Zheng H, Tornheim K, Han GS, Carman GM, Zoeller RA. Isolation of novel animal cell lines defective in glycerolipid biosynthesis reveals mutations in glucose-6-phosphate isomerase. J Biol Chem. 2010 Jan 8; 285(2):866-77.View Related Profiles. PMID: 19903819; PMCID: PMC2801288; DOI: 10.1074/jbc.M109.068213;.
  3. Getty-Kaushik L, Viereck JC, Goodman JM, Guo Z, LeBrasseur NK, Richard AM, Flanagan JN, Yaney GC, Hamilton JA, Tornheim K. Mice deficient in phosphofructokinase-M have greatly decreased fat stores. Obesity (Silver Spring). 2010 Mar; 18(3):434-40.View Related Profiles. PMID: 19779479; PMCID: PMC2871150; DOI: 10.1038/oby.2009.295;.
  4. Richard AM, Webb DL, Goodman JM, Schultz V, Flanagan JN, Getty-Kaushik L, Deeney JT, Yaney GC, Dunaway GA, Berggren PO, Tornheim K. Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion. Am J Physiol Endocrinol Metab. 2007 Sep; 293(3):E794-801.View Related Profiles. PMID: 17595219.
  5. Heart E, Yaney GC, Corkey RF, Schultz V, Luc E, Liu L, Deeney JT, Shirihai O, Tornheim K, Smith PJ, Corkey BE. Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. Biochem J. 2007 Apr 1; 403(1):197-205.View Related Profiles. PMID: 17181533; PMCID: PMC1828901.
  6. Nascimben L, Ingwall JS, Lorell BH, Pinz I, Schultz V, Tornheim K, Tian R. Mechanisms for increased glycolysis in the hypertrophied rat heart. Hypertension. 2004 Nov; 44(5):662-7. PMID: 15466668.
  7. Juntti-Berggren L, Webb DL, Arkhammar PO, Schultz V, Schweda EK, Tornheim K, Berggren PO. Dihydroxyacetone-induced oscillations in cytoplasmic free Ca2+ and the ATP/ADP ratio in pancreatic beta-cells at substimulatory glucose. J Biol Chem. 2003 Oct 17; 278(42):40710-6. PMID: 12917415.
  8. Itani SI, Saha AK, Kurowski TG, Coffin HR, Tornheim K, Ruderman NB. Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. Diabetes. 2003 Jul; 52(7):1635-40.View Related Profiles. PMID: 12829626.
  9. Cunningham BA, Richard AM, Dillon JS, Daley JT, Civelek VN, Deeney JT, Yaney GC, Corkey BE, Tornheim K. Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets. Biochem J. 2003 Jan 1; 369(Pt 1):173-8.View Related Profiles. PMID: 12356335; PMCID: PMC1223070.
  10. Yaney GC, Fairbanks JM, Deeney JT, Korchak HM, Tornheim K, Corkey BE. Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms. Am J Physiol Endocrinol Metab. 2002 Nov; 283(5):E880-8.View Related Profiles. PMID: 12376314.
Showing 10 of 77 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 68 publications over 25 distinct years, with a maximum of 7 publications in 1996

YearPublications
19803
19811
19831
19851
19862
19886
19891
19904
19912
19922
19934
19944
19953
19967
19973
19983
19993
20003
20014
20022
20033
20041
20072
20092
20121
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72 E. Concord St Silvio Conte (K)
Boston MA 02118
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