Jacqueline Sharon, PhD
Professor
Boston University School of Medicine
Dept of Pathology & Laboratory Medicine
Other Pathology Section

PhD, Columbia University
MPhil, Columbia University
MA, Queens College, City University of New York



Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Research Associate Professor
Boston University School of Medicine
Biochemistry




Protective and Pathogenic Bcell Epitopes in Tularemia
09/30/2009 - 09/29/2014 (PI)
HHS/PHS (Public Health Contracts) NIH NIAID

Polyclonal Antibody Libraries for Tularemia
09/01/2003 - 02/28/2009 (PI)
Boston Medical Center NIH NIAID
R21 AI83832-01

Polyclonal Antibody Libraries (Continuation of Structural Requirements of Antibody Combining Sites).
10/01/2001 - 08/31/2004 (PI)
Symphogen A/S

Recombinant Polyclonal Antibody Libraries for Breast Cancer Therapy
09/01/1998 - 08/31/2001 (PI)
Department of Defense/Army

Structural Requirements of Antibody Combining Sites
07/01/1996 - 06/30/2001 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5 R01 AI23909 14




Yr Title Project-Sub Proj Pubs
2011 STRUCTURAL ANALYSIS OF O-ANTIGEN FROM F TULARENSIS 5P41RR010888-15-5153 236
2010 STRUCTURAL ANALYSIS OF O-ANTIGEN FROM F TULARENSIS 5P41RR010888-14-6861 236
2010 Protective and pathogenic B cell epitopes in Francisella tularensis 272200900054C-1-0-1
2009 Protective and pathogenic B cell epitopes in Francisella tularensis 272200900054C-0-0-1
2000 STRUCTURAL REQUIREMENTS OF ANTIBODY COMBINING SITES 5R01AI023909-14 25
1999 POLYCLONAL ANTIBODY LIBRARIES FOR C PARVUM THERAPY 5U01AI040344-04 5
1999 STRUCTURAL REQUIREMENTS OF ANTIBODY COMBINING SITES 5R01AI023909-13 25
1998 POLYCLONAL ANTIBODY LIBRARIES FOR C PARVUM THERAPY 5U01AI040344-03 5
1998 STRUCTURAL REQUIREMENTS OF ANTIBODY COMBINING SITES 5R01AI023909-12 25
1997 POLYCLONAL ANTIBODY LIBRARIES FOR C PARVUM THERAPY 5U01AI040344-02 5
Showing 10 of 22 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Roche MI, Seaton BA, Sharon J. Functional and structural characterization of Francisella tularensis O-antigen antibodies at the low end of antigen reactivity. Monoclon Antib Immunodiagn Immunother. 2014 Aug; 33(4):235-45.View Related Profiles. PMID: 25171003; PMCID: PMC4151076; DOI: 10.1089/mab.2014.0022;.
  2. Lu Z, Rynkiewicz MJ, Madico G, Li S, Yang CY, Perkins HM, Sompuram SR, Kodela V, Liu T, Morris T, Wang D, Roche MI, Seaton BA, Sharon J. B-cell epitopes in GroEL of Francisella tularensis. PLoS One. 2014; 9(6):e99847.View Related Profiles. PMID: 24968190; PMCID: PMC4072690; DOI: 10.1371/journal.pone.0099847;.
  3. Sharon J, Rynkiewicz MJ, Lu Z, Yang CY. Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics. Immunology. 2014 May; 142(1):1-23.View Related Profiles. PMID: 24219801; PMCID: PMC3992043; DOI: 10.1111/imm.12213;.
  4. Lu Z, Perkins HM, Sharon J. Antibodies to both terminal and internal B-cell epitopes of Francisella tularensis O-polysaccharide produced by patients with tularemia. Clin Vaccine Immunol. 2014 Feb; 21(2):227-33.View Related Profiles. PMID: 24351753; PMCID: PMC3910946; DOI: 10.1128/CVI.00626-13;.
  5. Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Wang Q, Costello CE, Zaia J, Seaton BA, Sharon J. The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology. 2013 Nov; 140(3):374-89.View Related Profiles. PMID: 23844703; PMCID: PMC3800442; DOI: 10.1111/imm.12150;.
  6. Rynkiewicz MJ, Lu Z, Hui JH, Sharon J, Seaton BA. Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide. Biochemistry. 2012 Jul 17; 51(28):5684-94.View Related Profiles. PMID: 22747335; PMCID: PMC3566871.
  7. Lu Z, Madico G, Roche MI, Wang Q, Hui JH, Perkins HM, Zaia J, Costello CE, Sharon J. Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia. Immunology. 2012 Jul; 136(3):352-60.View Related Profiles. PMID: 22486311; PMCID: PMC3385035; DOI: 10.1111/j.1365-2567.2012.03589.x;.
  8. Wang Q, Shi X, Leymarie N, Madico G, Sharon J, Costello CE, Zaia J. A typical preparation of Francisella tularensis O-antigen yields a mixture of three types of saccharides. Biochemistry. 2011 Dec 20; 50(50):10941-50.View Related Profiles. PMID: 22091710; PMCID: PMC3238095; DOI: 10.1021/bi201450v;.
  9. Roche MI, Lu Z, Hui JH, Sharon J. Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide. Hybridoma (Larchmt). 2011 Feb; 30(1):19-28.View Related Profiles. PMID: 21466282; PMCID: PMC3119334; DOI: 10.1089/hyb.2010.0083;.
  10. Liebman MA, Roche MI, Williams BR, Kim J, Pageau SC, Sharon J. Antibody treatment of human tumor xenografts elicits active anti-tumor immunity in nude mice. Immunol Lett. 2007 Nov 30; 114(1):16-22. PMID: 17920694; PMCID: PMC2128754.
Showing 10 of 55 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 52 publications over 26 distinct years, with a maximum of 4 publications in 1982 and 1990 and 1993

YearPublications
19801
19812
19824
19841
19851
19861
19881
19891
19904
19913
19921
19934
19942
19962
19992
20003
20023
20032
20041
20051
20061
20072
20112
20122
20132
20143
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

immunology
infectious disease
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670 Albany St Biosquare III
Boston MA 02118
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