Karen R. Jacobson, MD, MPH
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Infectious Diseases Section

MD, Johns Hopkins University School of Medicine
MPH, Harvard School of Public Health



Dr. Karen Jacobson is an Assistant Professor of Medicine in the Section of Infectious Diseases, Boston University School of Medicine, with a secondary appointment in the Department of Epidemiology, Boston University School of Public Health. Dr. Jacobson’s research focuses on the epidemiology of drug resistant tuberculosis, including identification of social, biological, and economic determinants of and risk factors for drug resistance and approaches for improving TB outcomes in resource-limited settings. Dr. Jacobson has established a highly productive collaboration with researchers at Stellenbosch University in Cape Town, South Africa, investigating the drivers of drug resistance in the Western Cape Province of South Africa and working to identify potentially modifiable factors.

Assistant Professor
Boston University School of Public Health
Department of Epidemiology





The impact of alcohol consumption on TB treatment outcomes
04/08/2016 - 03/31/2021 (PI)
NIH-NIAID
1R01AI119037-01A1

URBAN ARCH (3/5) Uganda Cohort- TB prevention therapy for HIV-infected alcohol drinkers in Uganda…
09/22/2016 - 08/31/2017 (PI)
The Regents of the University of California NIH-NIAAA

Phase 2 Pharmacodynamic Study of Hidh-dose Levofloxacin in MDR-TB Treatment
01/01/2015 - 07/31/2017 (PI)
Trustees of Boston University NIH-NIAID

ASTMH Fellowship in Tropical Infectious Diseases
02/01/2013 - 01/31/2017 (PI)
American Society of Tropical Medicine and Hygiene

Geospatial clustering and molecular and social epidemiology of drug resistant TB
08/01/2013 - 12/31/2016 (PI)
NIH-FIC
5K01TW009213-6


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Jacobson KR, Barnard M, Kleinman MB, Streicher EM, Ragan EJ, White LF, Shapira O, Dolby T, Simpson J, Scott L, Stevens W, van Helden PD, Van Rie A, Warren RM. Implications of Failure to Routinely Diagnose Resistance to Second-Line Drugs in Patients With Rifampicin-Resistant Tuberculosis on Xpert MTB/RIF: A Multisite Observational Study. Clin Infect Dis. 2017 Jun 01; 64(11):1502-1508.View Related Profiles. PMID: 28199520; DOI: 10.1093/cid/cix128;.
  2. Jacobson KR. Tuberculosis. Ann Intern Med. 2017 Feb 07; 166(3):ITC17-ITC32. PMID: 28166561; DOI: 10.7326/AITC201702070;.
  3. Farhat MR, Sultana R, Iartchouk O, Bozeman S, Galagan J, Sisk P, Stolte C, Nebenzahl-Guimaraes H, Jacobson K, Sloutsky A, Kaur D, Posey J, Kreiswirth BN, Kurepina N, Rigouts L, Streicher EM, Victor TC, Warren RM, van Soolingen D, Murray M. Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value. Am J Respir Crit Care Med. 2016 Sep 01; 194(5):621-30.View Related Profiles. PMID: 26910495; PMCID: PMC5027209; DOI: 10.1164/rccm.201510-2091OC;.
  4. Farhat MR, Jacobson KR, Franke MF, Kaur D, Sloutsky A, Mitnick CD, Murray M. Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis. J Clin Microbiol. 2016 Mar; 54(3):727-33. PMID: 26763957; PMCID: PMC4767988; DOI: 10.1128/JCM.02775-15;.
  5. Jacobson KR, Sabin LL. Scaling up multidrug-resistant tuberculosis care in China. Lancet Glob Health. 2015 Apr; 3(4):e183-4.View Related Profiles. PMID: 25794667; PMCID: PMC4492310; DOI: 10.1016/S2214-109X(15)70093-8;.
  6. Farhat MR, Mitnick CD, Franke MF, Kaur D, Sloutsky A, Murray M, Jacobson KR. Concordance of Mycobacterium tuberculosis fluoroquinolone resistance testing: implications for treatment. Int J Tuberc Lung Dis. 2015 Mar; 19(3):339-41. PMID: 25686144; PMCID: PMC4486051; DOI: 10.5588/ijtld.14.0814;.
  7. Kendall EA, Theron D, Franke MF, van Helden P, Victor TC, Murray MB, Warren RM, Jacobson KR. Alcohol, hospital discharge, and socioeconomic risk factors for default from multidrug resistant tuberculosis treatment in rural South Africa: a retrospective cohort study. PLoS One. 2013; 8(12):e83480. PMID: 24349518; PMCID: PMC3862731; DOI: 10.1371/journal.pone.0083480;.
  8. Nebenzahl-Guimaraes H, Jacobson KR, Farhat MR, Murray MB. Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis. J Antimicrob Chemother. 2014 Feb; 69(2):331-42. PMID: 24055765; PMCID: PMC3886931; DOI: 10.1093/jac/dkt358;.
  9. Farhat MR, Shapiro BJ, Kieser KJ, Sultana R, Jacobson KR, Victor TC, Warren RM, Streicher EM, Calver A, Sloutsky A, Kaur D, Posey JE, Plikaytis B, Oggioni MR, Gardy JL, Johnston JC, Rodrigues M, Tang PK, Kato-Maeda M, Borowsky ML, Muddukrishna B, Kreiswirth BN, Kurepina N, Galagan J, Gagneux S, Birren B, Rubin EJ, Lander ES, Sabeti PC, Murray M. Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. Nat Genet. 2013 Oct; 45(10):1183-9.View Related Profiles. PMID: 23995135; DOI: 10.1038/ng.2747;.
  10. Jacobson KR, Theron D, Kendall EA, Franke MF, Barnard M, van Helden PD, Victor TC, Streicher EM, Murray MB, Warren RM. Implementation of genotype MTBDRplus reduces time to multidrug-resistant tuberculosis therapy initiation in South Africa. Clin Infect Dis. 2013 Feb; 56(4):503-8. PMID: 23090928; PMCID: PMC3552527; DOI: 10.1093/cid/cis920;.
Showing 10 of 16 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 16 publications over 9 distinct years, with a maximum of 3 publications in 2013

YearPublications
19992
20021
20101
20111
20122
20133
20152
20162
20172
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

alcohol
drug resistant tuberculosis
global health
spatial mapping
tuberculosis
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