Camron D. Bryant, PhD
Assistant Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

PhD, University of California at Los Angeles



Dr. Bryant is the Director of the Laboratory of Addiction Genetics. Dr. Bryant’s research program is focused on determining the genetic basis of behavioral and molecular traits relevant to substance dependence in mice. The ultimate goal is to improve our understanding of the neurobiological mechanisms of addiction and to translate these findings toward treatment and prevention strategies in humans. A current focus is to determine the genetic basis of the rewarding properties of opioids in mice by combining quantitative trait locus (QTL) analysis of behavior and gene expression in genetic reference populations that yield high resolution QTLs. This multi-pronged approach to gene mapping will accelerate the nomination of candidate genes for validation via direct gene targeting. A separate focus with regard to functional characterization of candidate genes is the dissection of the hypothesized opposing roles of casein kinase-1 (CK-1) isoforms in regulating dopaminergic signaling and the motivational properties of drugs of abuse. Last, Dr. Bryant has a longstanding interest in deciphering the neurobiological basis of the “placebo effect”, a phenomenon that has been hypothesized to be mediated by the reward expectation. He plans to develop and apply a forward genetic analysis toward Pavlovian conditioning mouse models across a variety of conditions that are notoriously sensitive to the placebo effect, including pain, anxiety, depression, and Parkinson’s Disease.

Director, Laboratory of Addiction Genetics
Boston University School of Medicine



2016 American College of Neuropsychopharmacology (ACNP): Elected Associate Member
2015 Boston University: Jack Spivack Excellence in Neurosciences Research Award
2014 International Behavioural and Neural Genetics Society (IBANGS): Young Scientist Award
2014 Winter Conference on Brain Research (WCBR): Junior Investigator Travel Fellowship
2013 World Congress of Psychiatric Genetics: Poster abstract selected for oral presentation
2013 International Behavioural and Neural Genetics Society (IBANGS): Outstanding Young Investigator Award for Junior Faculty
2012 International Behavioural and Neural Genetics Society (IBANGS): Travel Award
2011 American College of Neuropsychopharmacology (ACNP): Early Career Travel Award - Abstract selected for Breakout Session oral presentation
2011 NIDA: Travel Award for Miniconvention, “Frontiers in Addiction Research”
2011 International Behavioural and Neural Genetics Society (IBANGS): Travel Award
2011 International Narcotics Research Conference (INRC): Travel Award
2009 International Behavioural and Neural Genetics Society (IBANGS): Travel Award
2008 International Behavioural and Neural Genetics Society (IBANGS): Outstanding Young Investigator Award for Postdocs
2005 INRC: Travel Award
2002 INRC: Travel Award
2000 UCLA: Hatos Center for Neuropharmacology Training Fellowship
1999 UCLA: Achievement Rewards for College Scientists (ARCS) Scholarship
1998-1999 UIUC: Honors Program and thesis in the Department of Psychology


Genetic basis of binge eating and its motivational components in a reduced complexity cross
09/15/2015 - 08/31/2018 (PI)
NIH/National Institute on Drug Abuse
5R21DA038738-02

Bridging genetic variation with behavior: Molecular and functional mechanisms of quantitative trait gene regulation of the stimulant and addictive properties of methamphetamine in mice
07/01/2015 - 06/30/2018 (PI)
NIH/National Institute on Drug Abuse
5R01DA039168-02

Mapping G x E Interactions for Addiction Traits in a Reduced Complexity Cross
07/01/2014 - 06/30/2017 (PI)
NIH/National Institute on Drug Abuse
5R03DA038287-02

Bridging Genetic Variation with Behavior: Molecular and Functional Mechanisms.
05/01/2015 - 04/30/2017 (PI)
NIH/National Institute on Drug Abuse
3R00DA029635-05S2

Genetic Basis of Opioid Reward and Aversion in Mice
05/01/2013 - 04/30/2017 (PI)
NIH/National Institute on Drug Abuse
5R00DA029635-05S1




Yr Title Project-Sub Proj Pubs
2016 Genetic basis of binge eating and its motivational components in a reduced complexity cross 5R21DA038738-02 2
2016 Bridging genetic variation with behavior: Molecular and functional mechanisms of quantitative trait gene regulation of the stimulant and addictive properties of methamphetamine in mice 5R01DA039168-02 2
2016 Genetic Basis of Opioid Reward and Aversion in Mice 3R00DA029635-05S2 2
2015 Genetic basis of binge eating and its motivational components in a reduced complexity cross 1R21DA038738-01A1 2
2015 Genetic Basis of Opioid Reward and Aversion in Mice 5R00DA029635-05 2
2015 Genetic Basis of Opioid Reward and Aversion in Mice 3R00DA029635-05S1 2
2014 Mapping G x E Interactions for Addiction Traits in a Reduced Complexity Cross 1R03DA038287-01 2
2014 Genetic Basis of Opioid Reward and Aversion in Mice 5R00DA029635-04 2
2013 Genetic Basis of Opioid Reward and Aversion in Mice 4R00DA029635-03 2
2012 Genetic Basis of Opioid Reward and Aversion in Mice 5K99DA029635-02 5
Showing 10 of 12 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Goldberg LR, Kirkpatrick SL, Yazdani N, Luttik KP, Lacki OA, Keith Babbs R, Jenkins DF, Evan Johnson W, Bryant CD. Casein kinase 1-epsilon deletion increases mu opioid receptor-dependent behaviors and binge eating1. Genes Brain Behav. 2017 Jun 08. PMID: 28594147.
  2. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Biol Psychiatry. 2017 May 01; 81(9):757-769.View Related Profiles. PMID: 27914629; DOI: 10.1016/j.biopsych.2016.10.021;.
  3. Yazdani N, Shen Y, Johnson WE, Bryant CD. Striatal transcriptome analysis of a congenic mouse line (chromosome 11: 50-60Mb) exhibiting reduced methamphetamine sensitivity. Genom Data. 2016 Jun; 8:77-80.View Related Profiles. PMID: 27222804; DOI: 10.1016/j.gdata.2016.03.009;.
  4. Bryant CD, Yazdani N. RNA-binding proteins, neural development and the addictions. Genes Brain Behav. 2016 Jan; 15(1):169-86.View Related Profiles. PMID: 26643147; PMCID: PMC4944654; DOI: 10.1111/gbb.12273;.
  5. Yazdani N, Parker CC, Shen Y, Reed ER, Guido MA, Kole LA, Kirkpatrick SL, Lim JE, Sokoloff G, Cheng R, Johnson WE, Palmer AA, Bryant CD. Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet. 2015 Dec; 11(12):e1005713.View Related Profiles. PMID: 26658939; PMCID: PMC4675533; DOI: 10.1371/journal.pgen.1005713;.
  6. Kirkpatrick SL, Bryant CD. Behavioral architecture of opioid reward and aversion in C57BL/6 substrains. Front Behav Neurosci. 2014; 8:450. PMID: 25628547; DOI: 10.3389/fnbeh.2014.00450;.
  7. Zhou L, Bryant CD, Loudon A, Palmer AA, Vitaterna MH, Turek FW. The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice. Sleep. 2014; 37(4):785-93, 793A-793C. PMID: 24744456; PMCID: PMC3972422; DOI: 10.5665/sleep.3590;.
  8. Bryant CD, Guido MA, Kole LA, Cheng R. The heritability of oxycodone reward and concomitant phenotypes in a LG/J x SM/J F48 mouse advanced intercross line. Addiction Biology. 2014.
  9. Bryant CD, Guido MA, Kole LA, Cheng R. The heritability of oxycodone reward and concomitant phenotypes in a LG/J?×?SM/J mouse advanced intercross line. Addict Biol. 2014 Jul; 19(4):552-61. PMID: 23231598; PMCID: PMC4300855; DOI: 10.1111/adb.12016;.
  10. Bryant CD, Kole LA, Guido MA, Cheng R, Palmer AA. Methamphetamine-induced conditioned place preference in LG/J and SM/J mouse strains and an F45/F46 advanced intercross line. Front Genet. 2012; 3:126. PMID: 22798962; PMCID: PMC3393886; DOI: 10.3389/fgene.2012.00126;.
Showing 10 of 23 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 23 publications over 12 distinct years, with a maximum of 3 publications in 2003 and 2016

YearPublications
20033
20051
20062
20071
20082
20092
20112
20122
20142
20152
20163
20171

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Boston MA 02118
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