Francesca Seta, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine (Vascular Biology Unit) Section

PhD, New York Medical College
MSc, Università G. d'Annunzio



2014-2016 BUMC- Evans Center: Evans Center Fellow Award


Boston Nutrition Obesity Research Center
04/01/2017 - 03/31/2018 (PI)
Boston Medical Center Corporation NIH NIDDK
5P30DK046200-25

Sirtuin1 in Aortic Remodeling and Dissection
07/01/2014 - 06/30/2016 (PI)
National Marfan Foundation




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta. 2017 Jun; 1863(6):1382-1391.View Related Profiles. PMID: 28185955; DOI: 10.1016/j.bbadis.2017.02.004;.
  2. Grzegorzewska AP, Seta F, Han R, Czajka CA, Makino K, Stawski L, Isenberg JS, Browning JL, Trojanowska M. Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways. Sci Rep. 2017 Feb 02; 7:41605.View Related Profiles. PMID: 28150703; DOI: 10.1038/srep41605;.
  3. Han J, Weisbrod RM, Shao D, Watanabe Y, Yin X, Bachschmid MM, Seta F, Janssen-Heininger YM, Matsui R, Zang M, Hamburg NM, Cohen RA. The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells. Redox Biol. 2016 Oct; 9:306-319.View Related Profiles. PMID: 27693992; DOI: 10.1016/j.redox.2016.09.003;.
  4. Nicholson CJ, Seta F, Lee S, Morgan KG. MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways. J Cell Mol Med. 2017 Jan; 21(1):81-95.View Related Profiles. PMID: 27502584; DOI: 10.1111/jcmm.12940;.
  5. Fry JL, Al Sayah L, Weisbrod RM, Van Roy I, Weng X, Cohen RA, Bachschmid MM, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension. 2016 Sep; 68(3):775-84.View Related Profiles. PMID: 27432859; PMCID: PMC4982825; DOI: 10.1161/HYPERTENSIONAHA.116.07622;.
  6. Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Lee KS, Hammock BD, Sadoshima J, Cohen RA, Zeng C. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 2016 Mar; 92:30-40.View Related Profiles. PMID: 26812119; PMCID: PMC5008453; DOI: 10.1016/j.yjmcc.2016.01.020;.
  7. Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins. PLoS One. 2015; 10(12):e0144025.View Related Profiles. PMID: 26642319; PMCID: PMC4671598; DOI: 10.1371/journal.pone.0144025;.
  8. Fry JL, Shiraishi Y, Turcotte R, Yu X, Gao YZ, Akiki R, Bachschmid M, Zhang Y, Morgan KG, Cohen RA, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension. J Am Heart Assoc. 2015 Sep; 4(9):e002384.View Related Profiles. PMID: 26376991; PMCID: PMC4599512; DOI: 10.1161/JAHA.115.002384;.
  9. Seta F, Cohen RA. The endothelium: paracrine mediator of aortic dissection. Circulation. 2014 Jun 24; 129(25):2629-32.View Related Profiles. PMID: 24807873; PMCID: PMC4100940; DOI: 10.1161/CIRCULATIONAHA.114.010609;.
  10. Qin Z, Hou X, Weisbrod RM, Seta F, Cohen RA, Tong X. Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells. J Mol Cell Cardiol. 2014 Jul; 72:56-63.View Related Profiles. PMID: 24631774; PMCID: PMC4037381; DOI: 10.1016/j.yjmcc.2014.02.019;.
Showing 10 of 27 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 15 distinct years, with a maximum of 4 publications in 2016

YearPublications
19991
20001
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20092
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20132
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20172

I am a research scientist with expertise in vascular surgery and hemodynamic measurements in small animals. My research interest is vascular biology with a focus on diseases of large arteries, such as arterial stiffness and aortic aneurysm/dissection, and hypertension. I have mentored, as direct supervisor, more than 15 undergraduate, graduate and medical students, mainly during their laboratory training. I am available as peer mentor to early stage investigators and as research mentor to students and post-docs to share my technical and knowledge expertise as well as science culture.

Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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