Richard Wainford, PhD
Associate Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

PhD, University of Aberdeen



Background:
Dr Wainford obtained a Bachelors in Zoology from the University of Wales, Cardiff in 1999. Dr Wainford undertook his Graduate training in the Laboratory of Molecular Pharmacology and Toxicology in the Department of Medicine and Therapeutics at the University of Aberdeen School of Medicine under the guidance of Professor Hawksworth, earning a PhD in Molecular Pharmacology in 2004. Dr. Wainford then completed a 2-year post-doctoral fellowship in the Department of Pharmacology at the Louisiana State University Health Sciences Center in New Orleans in Cardiovascular & Renal Pharmacology under the mentorship of Dr. Kapusta. Dr. Wainford then became an Instructor of Pharmacology in 2008, remaining in the laboratory of Dr. Kapusta until his promotion to the rank of Assistant Professor in 2010. Dr. Wainford joined the Department of Pharmacology & Experimental Therapeutics at the Boston University School of Medicine and the Whitaker Cardiovascular Institute in 2011 as an Assistant Professor.

Research Summary:
Dr. Wainford is the director of the Laboratory of Cardio-Renal Research. Dr. Wainford’s research interests focus on the central neural control of fluid and electrolyte homeostasis and blood pressure regulation. Dr. Wainford’s laboratory utilizes an integrated physiological, pharmacological, molecular, and gene-targeting approach to investigate the anti-hypertensive role(s) of central G-alpha-subunit proteins in the endogenous GPCR-activated pathways that regulate central sympatheticoutflow, fluid and electrolyte homeostasis, and systemic blood pressure regulation in salt-resistant and salt-sensitive animal models.The major goal of Dr. Wainford’s research is identifying the underlying pathophysiology of and potential treatments for hypertension. Current studies concern the role of central G-alpha subunit protein gated pathways in mediating the neural control of kidney function and systemic arterial blood pressure.

Associate Professor
Boston University School of Medicine
Medicine
Cardiovascular Medicine Section


2014 The American Physiology Society: Arthur C. Guyton Award for Excellence in Integrative Physiology
2014 Howard Hughes Medical Institute (HHMI): Summer Research Program Award
2013 American Heart Association Council for High Blood Pressure: Research Harry Goldblatt New Investigator
2013 The American Physiological Society Central Nervous System: New Investigator Award
2013 Endocrine Society: Early Investigator Award
2013 The American Physiological Society: Shih-Chun Wang Young Investigator Award
2012 International Society of Hypertension: New Investigator of the Month (December)
2012 The American Physiological Society: Dean Franklin Young Investigator Award
2011 The American Physiological Society: Research Career Enhancement Award


Brain G-Alpha Subunit Protein Mediated Neural Control of Blood Pressure
06/01/2016 - 05/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5K02HL112718-05

Brain G-alpha subunit protein mediated neural control of blood pressure
10/01/2011 - 07/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL107330-05

Mentoring in neural and Cardiorenal Pathophysiology
07/01/2016 - 06/30/2017 (PI)
American Heart Association

Brain G-Alpha Subunit Protein Mediated Neural Control of Blood Pressure
08/20/2013 - 05/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5K02HL112718-03



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Frame AA, Wainford RD. Renal sodium handling and sodium sensitivity. Kidney Res Clin Pract. 2017 Jun; 36(2):117-131.View Related Profiles. PMID: 28680820.
  2. Wainford R, Carmichael C, Walsh K. OS 11-01 Afferent renal nerve modulation of sodium homeostasis and blood pressure: A sodium sensitive PVN Gai2 protein dependent mechanism countering the development of salt-sensitive hypertension? J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e74.View Related Profiles. PMID: 27753968.
  3. Wainford R, Walsh K. OS 29-04 SYMPATHETIC NERVOUS SYSTEM REGULATION OF THE RENAL NCC AND BLOOD PRESSURE DURING HIGH DIETARY SALT INTAKE. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e253-e254. PMID: 27754152.
  4. Wainford R. ED 09-1 RENAL SODIUM HANDLING AND SALT SENSITIVITY. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e537. PMID: 27754276.
  5. Frame AA, Carmichael CY, Wainford RD. Renal Afferents. Curr Hypertens Rep. 2016 Sep; 18(9):69.View Related Profiles. PMID: 27595156; PMCID: PMC5011151; DOI: 10.1007/s11906-016-0676-z;.
  6. Walsh KR, Kuwabara JT, Shim JW, Wainford RD. Norepinephrine-evoked salt-sensitive hypertension requires impaired renal sodium chloride cotransporter activity in Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15; 310(2):R115-24.View Related Profiles. PMID: 26608659; PMCID: PMC4796647; DOI: 10.1152/ajpregu.00514.2014;.
  7. Carmichael CY, Carmichael AC, Kuwabara JT, Cunningham JT, Wainford RD. Impaired sodium-evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious Sprague-Dawley rats lacking central Gai2 proteins. Acta Physiol (Oxf). 2016 Mar; 216(3):314-29. PMID: 26412230; PMCID: PMC4764872; DOI: 10.1111/apha.12610;.
  8. Brouwers S, Smolders I, Wainford RD, Dupont AG. Correction: Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats. Clin Sci (Lond). 2015 Oct; 129(7):673. PMID: 26186745; DOI: 10.1042/CS1290673b;.
  9. Carmichael CY, Wainford RD. Brain Gai 2 -subunit proteins and the prevention of salt sensitive hypertension. Front Physiol. 2015; 6:233.View Related Profiles. PMID: 26347659; DOI: 10.3389/fphys.2015.00233;.
  10. Brouwers S, Smolders I, Wainford RD, Dupont AG. Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats. Clin Sci (Lond). 2015 Jul; 129(1):81-92. PMID: 25655919; PMCID: PMC4430196; DOI: 10.1042/CS20140776;.
Showing 10 of 29 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 10 distinct years, with a maximum of 9 publications in 2015

YearPublications
20071
20083
20091
20101
20124
20131
20144
20159
20164
20171

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700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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