Ali Guermazi, MD, PhD
Professor
Boston University School of Medicine
Dept of Radiology
Musculoskeletal Radiology Section

MD, University of Sfax
PhD, Jikei University School of Medicine



Dr. Guermazi is a French board-certified radiologist. Prior to joining Boston University, he was Director of the Osteoporosis and Arthritis Research Group (OARG) at University of California at San Francisco (UCSF) and then Director of Clinical Research at Synarc, Inc. in San Francisco. Dr. Guermazi interest is musculoskeletal diseases, in particular note are his scientific contributions in the diagnosis and disease progression assessment of osteoarthritis using MRI. His work has focused on identifying structural risk factors for developing and worsening osteoarthritis. Dr. Guermazi had been involved in developing several original and widely accepted radiological methods to assess osteoarthritis disease risk and progression, including the WORMS, BLOKS and MOAKS for the knee, HOAMS for the hip and fixed-flexion radiography for measuring joint space width. Dr. Guermazi has been involved as an MRI reader for the past 14 years in several large U.S. studies including the Health Aging and Body Composition (Health ABC) study, the Boston Osteoarthritis Knee study (BOKS), the Multi-center Osteoarthritis STudy (MOST), the Framingham study, Osteoarthritis Initiative (OAI), and other large NIH-funded studies, as well as several Pharmaceutical-sponsored clinical trials. He is author of over 275 peer-reviewed publications and Investigator on numerous research grants related to MRI reading for Osteoarthritis.

Section Chief
Boston University School of Medicine
Radiology
Musculoskeletal Radiology Section

Assistant Dean
Boston University School of Medicine
Diversity & Multicultural Affairs


Active Staff Privileges
Boston Medical Center
Radiology




Gadolinium Distribution in Rat Brain After Systemic Administration of Gadolinium-Based Contrast Agents
10/01/2016 - 06/18/2019 (Co-PI)
PI: Lee E. Goldstein, MD, PhD
GE Healthcare, Inc.

Characterizing Electrostatic Interactions Between Glycosaminoglycans and Cationic Small Molecules
03/05/2012 - 01/31/2017 (Co-PI)
PI: Mark Grinstaff, PhD
NIH/National Institutes of Health
5R01GM098361-04

Evaluation of Feasibility of Volume Rad X-Ray Versus Conventional X-Ray and 3.0T MRI in Bi-Lateral Knees in With and Without Osteoarthritis
02/01/2009 - 04/30/2010 (PI)
General Electric Company


Risk of Incident Knee OA and Clinical Outcomes Based on Imaging Biomarkers
09/15/2014 - 07/31/2017 (PI)
University of Arizona NIH-NIAMS

Partial Meniscectomy vs Nonoperative Management in Meniscal Tear with OA: a RCT
08/01/2012 - 07/31/2017 (PI)
Brigham & Women's NIH-NIAMS

Mechanisms and Clinical Importance of Hyperkyphosis: The Framingham Study
09/30/2011 - 08/31/2016 (PI)
Hebrew Rehab C Aged NIH-NIA

Partial meniscectomy vs. nonperative management in meniscal tear with OA: an RCT
09/28/2009 - 09/27/2013 (PI)
Brigham & Women's NIH-NIAMS

Central Reading of Knee MRI in Osteroarthritis Patients
11/01/2008 - 10/31/2011 (PI)
Arthritis Centre of Canada

Osteoartritis Initiave WORMS - BLOKS Comparison Study
04/01/2008 - 10/14/2009 (PI)
Univ of California, San Francisco NIH-NIAMS

Development for a model for the MRI progression of knee osteoarthritis
03/01/2007 - 02/28/2009 (PI)
Arthritis Centre of Canada University of Britis



Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Roemer FW, Kijowski R, Guermazi A. Editorial: from theory to practice - the challenges of compositional MRI in osteoarthritis research. Osteoarthritis Cartilage. 2017 Aug 24. PMID: 28844567.
  2. Lorbergs AL, Murabito JM, Jarraya M, Guermazi A, Allaire BT, Yang L, Kiel DP, Cupples LA, Bouxsein ML, Travison TG, Samelson EJ. Thoracic Kyphosis and Physical Function: The Framingham Study. J Am Geriatr Soc. 2017 Aug 21.View Related Profiles. PMID: 28832926.
  3. Wallace G, Cro S, Doré C, King L, Kluzek S, Price A, Roemer F, Guermazi A, Keen R, Arden N. Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy. Arthritis Care Res (Hoboken). 2017 Sep; 69(9):1340-1348. PMID: 27998036; DOI: 10.1002/acr.23162;.
  4. Loeser RF, Beavers DP, Bay-Jensen AC, Karsdal MA, Nicklas BJ, Guermazi A, Hunter DJ, Messier SP. Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis trial (IDEA). Osteoarthritis Cartilage. 2017 Jul 27. PMID: 28756278.
  5. Deveza LA, Kraus VB, Collins JE, Guermazi A, Roemer FW, Bowes M, Nevitt MC, Ladel C, Hunter DJ. Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2017 Aug; 69(8):1179-1191. PMID: 27723280; DOI: 10.1002/acr.23121;.
  6. Kaukinen P, Podlipská J, Guermazi A, Niinimäki J, Lehenkari P, Roemer FW, Nieminen MT, Koski JM, Saarakkala S, Arokoski JPA. Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis - the Oulu Knee Osteoarthritis study. Osteoarthritis Cartilage. 2017 Jul 08. PMID: 28698105.
  7. Radojcic MR, Thudium CS, Henriksen K, Tan K, Karlsten R, Dudley A, Chessell I, Karsdal MA, Bay-Jensen AC, Crema MD, Guermazi A. Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients. Pain. 2017 Jul; 158(7):1254-1263.View Related Profiles. PMID: 28333699; DOI: 10.1097/j.pain.0000000000000908;.
  8. Stewart RC, Patwa AN, Lusic H, Freedman JD, Wathier M, Snyder BD, Guermazi A, Grinstaff MW. Synthesis and Preclinical Characterization of a Cationic Iodinated Imaging Contrast Agent (CA4+) and Its Use for Quantitative Computed Tomography of Ex Vivo Human Hip Cartilage. J Med Chem. 2017 Jul 13; 60(13):5543-5555.View Related Profiles. PMID: 28616978.
  9. Macri EM, Felson DT, Zhang Y, Guermazi A, Roemer FW, Crossley KM, Khan KM, Stefanik JJ. Patellofemoral morphology and alignment: reference values and dose-response patterns for the relation to MRI features of patellofemoral osteoarthritis. Osteoarthritis Cartilage. 2017 Oct; 25(10):1690-1697.View Related Profiles. PMID: 28648740.
  10. Hayashi D, Roemer FW, Jarraya M, Guermazi A. Imaging in Osteoarthritis. Radiol Clin North Am. 2017 Sep; 55(5):1085-1102. PMID: 28774450.
Showing 10 of 484 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 484 publications over 24 distinct years, with a maximum of 52 publications in 2015

YearPublications
19942
19957
19969
19979
19984
19995
20008
20019
200214
200312
200418
20059
200619
200711
200824
200936
201031
201135
201233
201340
201433
201552
201640
201724
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