Neil B. Ruderman, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes & Nutrition Section

MD, University of Pittsburgh
DPhil, University of Oxford



Expertise in carrying out metabolic research, writing grants and manuscripts. I also have experience in mentoring young investigators and working as a member of various national and international scientific groups. Finally, I have organized many multi-investigator research groups and scientific meetings.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Professor
Boston University School of Medicine
Physiology & Biophysics


Active Staff Privileges
Boston Medical Center
Medicine
Endocrinology, Diabetes & Nutrition Section



Metabolism, Endocrinology, and Obesity Training Grant
05/15/1998 - 04/30/2008 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5 T32 DK07201 31

Mentor Based Postdoctoral Fellowship Program
07/01/1997 - 06/30/2000 (PI)
American Diabetes Association


Metabolism, Endocrinology & Obesity Training Grant
07/01/2014 - 06/30/2019 (PI)
NIH-NIDDK
5T32DK007201-38

Epidermal Homeostasis and the SIRT1/LKB1/AMPK Signaling Pathway
07/01/2015 - 06/30/2017 (PI)
L'Oreal USA

The AMPK/SIRT1 Partnership and its Biological Relevance
06/17/2011 - 05/31/2017 (PI)
NIH-NIDDK
5R01 DK019514-35

AMPK, SIRT1 and mTOR: Mediators of Nutrient Excess
08/10/2011 - 06/30/2015 (PI)
NIH-NIDDK
5R01 DK067509-09

AMPK Regulation and Biological Relevance
07/01/2011 - 06/30/2015 (PI)
Amer Diabetes Asso

AMPK Core A
04/15/2009 - 01/31/2015 (PI)
NIH-NHLBI
5P01 HL068758-10

AMPK Project 1
04/15/2009 - 01/31/2015 (PI)
NIH-NHLBI
5P01 HL068758-10

AMPK & Adipose Tissue Biology in Bariatric Surgery Patients
07/16/2012 - 06/30/2014 (PI)
NIH-NIDDK
1R24 DK094749-01

Determinants and Cardiovascular Consequences of Diabetes in Older Adults
09/01/2009 - 06/30/2014 (PI)
Beth Israel NIH-NHLBI
5R01 HL094555-04

Metabolism Endocrinology and Obesity Training Grant
05/01/2008 - 06/30/2014 (PI)
NIH-NIDDK
5T32 DK007201-36

Showing 10 of 35 results. Show All Results


Yr Title Project-Sub Proj Pubs
2016 Metabolism, Endocrinology and Obesity Training Grant 5T32DK007201-39 47
2014 AMPK, SIRT1 and mTOR:Mediators of Nutrient Excess 5R01DK067509-09 29
2014 Metabolism, Endocrinology and Obesity Training Grant 2T32DK007201-37 47
2014 The AMPK/SIRT1 Partnershipand Its Biological Relevance 5R01DK019514-34 83
2013 AMPK Endothelial Cell Dysfunction and the Metabolic Syndrome (PROGRAM PROJECT) 5P01HL068758-10 93
2013 AMPK, SIRT1 and mTOR:Mediators of Nutrient Excess 5R01DK067509-08 29
2013 The AMPK/SIRT1 Partnershipand Its Biological Relevance 5R01DK019514-33 83
2013 AMPK, Metabolic and Inflammatory Stress and the Endothelial Cell 5P01HL068758-10-5223 93
2013 Administrative Core 5P01HL068758-10-5226 93
2012 AMPK and adipose tissue biology in bariatric surgery patients 1R24DK094749-01 4
Showing 10 of 106 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Allen KM, Coughlan KA, Mahmood FN, Valentine RJ, Ruderman NB, Saha AK. The effects of troglitazone on AMPK in HepG2 cells. Arch Biochem Biophys. 2017 Jun 01; 623-624:49-57.View Related Profiles. PMID: 28526426.
  2. Attané C, Peyot ML, Lussier R, Poursharifi P, Zhao S, Zhang D, Morin J, Pineda M, Wang S, Dumortier O, Ruderman NB, Mitchell GA, Simons B, Madiraju SR, Joly E, Prentki M. A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice. Diabetologia. 2016 Dec; 59(12):2654-2663. PMID: 27677764.
  3. Weikel KA, Cacicedo JM, Ruderman NB, Ido Y. Knockdown of GSK3ß increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016 Oct; 36(5).View Related Profiles. PMID: 27534430; PMCID: PMC5025810; DOI: 10.1042/BSR20160174;.
  4. Pepin É, Al-Mass A, Attané C, Zhang K, Lamontagne J, Lussier R, Madiraju SR, Joly E, Ruderman NB, Sladek R, Prentki M, Peyot ML. Pancreatic ß-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Ce, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression. PLoS One. 2016; 11(4):e0153017. PMID: 27043434; PMCID: PMC4820227; DOI: 10.1371/journal.pone.0153017;.
  5. Coughlan KA, Valentine RJ, Sudit BS, Allen K, Dagon Y, Kahn BB, Ruderman NB, Saha AK. PKD1 Inhibits AMPKa2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells. J Biol Chem. 2016 Mar 11; 291(11):5664-75.View Related Profiles. PMID: 26797128; PMCID: PMC4786706; DOI: 10.1074/jbc.M115.696849;.
  6. Weikel KA, Ruderman NB, Cacicedo JM. Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights. Metabolism. 2016 May; 65(5):634-45.View Related Profiles. PMID: 27085772; PMCID: PMC4834453; DOI: 10.1016/j.metabol.2016.01.005;.
  7. Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M. Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. Diabetes. 2015 Oct; 64(10):e38-9. PMID: 26405280; DOI: 10.2337/dbi15-0002;.
  8. Xu XJ, Apovian C, Hess D, Carmine B, Saha A, Ruderman N. Improved Insulin Sensitivity 3 Months After RYGB Surgery Is Associated With Increased Subcutaneous Adipose Tissue AMPK Activity and Decreased Oxidative Stress. Diabetes. 2015 Sep; 64(9):3155-9.View Related Profiles. PMID: 26001396; PMCID: PMC4542447; DOI: 10.2337/db14-1765;.
  9. Coughlan KA, Balon TW, Valentine RJ, Petrocelli R, Schultz V, Brandon A, Cooney GJ, Kraegen EW, Ruderman NB, Saha AK. Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats. PLoS One. 2015; 10(5):e0127388.View Related Profiles. PMID: 25996822; PMCID: PMC4440828; DOI: 10.1371/journal.pone.0127388;.
  10. Brandon AE, Tid-Ang J, Wright LE, Stuart E, Suryana E, Bentley N, Turner N, Cooney GJ, Ruderman NB, Kraegen EW. Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance. PLoS One. 2015; 10(3):e0121959. PMID: 25798922; PMCID: PMC4370576; DOI: 10.1371/journal.pone.0121959;.
Showing 10 of 325 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 270 publications over 38 distinct years, with a maximum of 20 publications in 1986

YearPublications
19807
19816
198210
19834
198410
19855
198620
19871
198810
19894
19904
19918
199210
19937
19947
19955
19963
19975
19983
199911
20005
20016
200218
200311
200411
200515
20066
20072
20083
20098
20108
20117
20126
20136
20146
20156
20165
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

AMP activated protein kinase
Atherosclerosis
Diabetes
Exercise
Metabolic Syndrome
Metabolism
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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