Catherine Grgicak, PhD
Assistant Professor
Boston University School of Medicine
Dept of Anatomy & Neurobiology

PhD, University of Ottawa
MS, University of Alabama at Birmingham



Expertise includes:

Interpretation of complex, low-level DNA signal;
Applications of Laser Microdissection in Forensic DNA Analysis;
Evaluation of Degraded DNA and its effect on forensic DNA mixture interpretation;
Electrochemical Biosensors - Immobilization of DNA on Gold;
Determining the Number of Contributors to complex, low-level DNA signal

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Establishing Exclusion Criteria and the Significance of Inclusion: Developing Tools for the Interpretation of Complex DNA Mixtures
01/01/2015 - 12/31/2017 (PI)
Department of Justice/NIJ

Collection Methods and Protocol Optimization for the EasiCollect+ DNA Collection Device
04/11/2016 - 07/20/2017 (PI)
GE Healthcare Bio-Sciences Ltd.

A Tool for Determining the Number of Contributors: Interpreting Complex, Compromised, Low-Template DNA
09/08/2014 - 02/07/2017 (PI)
Department of Defense/ARO

Establishing Exclusion Criteria and Significance of Inclusion for Complex Low-Template DNA Mixtures
01/01/2013 - 03/31/2015 (PI)
Department of Justice/NIJ

Low-temperature DNA mixture interpretation: Determining the number of contributors
01/01/2012 - 08/31/2014 (PI)
Department of Justice/NIJ




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Duffy KR, Gurram N, Peters KC, Wellner G, Grgicak CM. Exploring STR signal in the single- and multicopy number regimes: Deductions from an in silico model of the entire DNA laboratory process. Electrophoresis. 2017 Mar; 38(6):855-868. PMID: 27981603; DOI: 10.1002/elps.201600385;.
  2. Alfonse LE, Tejada G, Swaminathan H, Lun DS, Grgicak CM. Inferring the Number of Contributors to Complex DNA Mixtures Using Three Methods: Exploring the Limits of Low-Template DNA Interpretation. J Forensic Sci. 2017 Mar; 62(2):308-316. PMID: 27907229; DOI: 10.1111/1556-4029.13284;.
  3. Swaminathan H, Garg A, Grgicak CM, Medard M, Lun DS. CEESIt: A computational tool for the interpretation of STR mixtures. Forensic Sci Int Genet. 2016 May; 22:149-60. PMID: 26946255; DOI: 10.1016/j.fsigen.2016.02.005;.
  4. Rowan KE, Wellner GA, Grgicak CM. Exploring the Impacts of Ordinary Laboratory Alterations During Forensic DNA Processing on Peak Height Variation, Thresholds, and Probability of Dropout. J Forensic Sci. 2016 Jan; 61(1):177-85. PMID: 26280243; DOI: 10.1111/1556-4029.12899;.
  5. Mönich UJ, Duffy K, Médard M, Cadambe V, Alfonse LE, Grgicak C. Probabilistic characterisation of baseline noise in STR profiles. Forensic Sci Int Genet. 2015 Nov; 19:107-22. PMID: 26218981; DOI: 10.1016/j.fsigen.2015.07.001;.
  6. Swaminathan H, Grgicak CM, Medard M, Lun DS. NOCIt: a computational method to infer the number of contributors to DNA samples analyzed by STR genotyping. Forensic Sci Int Genet. 2015 May; 16:172-80. PMID: 25625964; DOI: 10.1016/j.fsigen.2014.11.010;.
  7. Oechsle CS, Haddad S, Sgueglia JB, Grgicak CM. Screening biological stains with qPCR versus lateral flow immunochromatographic test strips: a quantitative comparison using analytical figures of merit. J Forensic Sci. 2014 Jan; 59(1):199-207. PMID: 24117798; DOI: 10.1111/1556-4029.12284;.
  8. Wogan ME, Webster-Hoffmeyer KS, Grgicak CM. Corrosion behaviour of four handguns in aqueous environments: corrosion product characterization and effects on estimating the time since deposition. Sci Justice. 2013 Sep; 53(3):363-70. PMID: 23937948; DOI: 10.1016/j.scijus.2013.04.010;.
  9. Hennekens CM, Cooper ES, Cotton RW, Grgicak CM. The effects of differential extraction conditions on the premature lysis of spermatozoa. J Forensic Sci. 2013 May; 58(3):744-52.View Related Profiles. PMID: 23550664; DOI: 10.1111/1556-4029.12098;.
  10. Bregu J, Conklin D, Coronado E, Terrill M, Cotton RW, Grgicak CM. Analytical thresholds and sensitivity: establishing RFU thresholds for forensic DNA analysis. J Forensic Sci. 2013 Jan; 58(1):120-9.View Related Profiles. PMID: 23130820; DOI: 10.1111/1556-4029.12008;.
Showing 10 of 21 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 21 publications over 11 distinct years, with a maximum of 3 publications in 2005 and 2013

YearPublications
20053
20062
20072
20082
20101
20122
20133
20141
20152
20162
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Electrochemistry
Forensic DNA Analysis

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
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