Irina N. Gorshkova, PhD
Senior Research Scientist
Boston University School of Medicine
Dept of Physiology & Biophysics
Cardiovascular Medicine Section

PhD, National Cardiology Research Center
MS, Moscow State University



1994-1996 Russian Government Program on Atherosclerosis: Investigator Award
1994 International Atherosclerosis Society: Visiting Fellowship Award
1993 The Deutsche Forschungsgemeinschaft : Fellowship Award
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Gorshkova IN, Mei X, Atkinson D. Binding of human apoA-I[K107del] variant to TG-rich particles: implications for mechanisms underlying hypertriglyceridemia. J Lipid Res. 2014 Sep; 55(9):1876-85.View Related Profiles. PMID: 24919401; PMCID: PMC4617355; DOI: 10.1194/jlr.M047241;.
  2. Kateifides AK, Gorshkova IN, Duka A, Chroni A, Kardassis D, Zannis VI. Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL. J Lipid Res. 2011 Jul; 52(7):1363-72.View Related Profiles. PMID: 21504968; PMCID: PMC3122915; DOI: 10.1194/jlr.M012989;.
  3. Gorshkova IN, Atkinson D. Enhanced binding of apolipoprotein A-I variants associated with hypertriglyceridemia to triglyceride-rich particles. Biochemistry. 2011 Mar 29; 50(12):2040-7.View Related Profiles. PMID: 21288012; DOI: 10.1021/bi200158b;.
  4. Gorshkova IN, Kypreos KE, Gantz DL, Zannis VI, Atkinson D. Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia. Biochemistry. 2008 Nov 25; 47(47):12644-54.View Related Profiles. PMID: 18959431; PMCID: PMC2748909; DOI: 10.1021/bi8015857;.
  5. Gorshkova IN, Liu T, Kan HY, Chroni A, Zannis VI, Atkinson D. Structure and stability of apolipoprotein a-I in solution and in discoidal high-density lipoprotein probed by double charge ablation and deletion mutation. Biochemistry. 2006 Jan 31; 45(4):1242-54.View Related Profiles. PMID: 16430220; PMCID: PMC2532493.
  6. Chroni A, Kan HY, Kypreos KE, Gorshkova IN, Shkodrani A, Zannis VI. Substitutions of glutamate 110 and 111 in the middle helix 4 of human apolipoprotein A-I (apoA-I) by alanine affect the structure and in vitro functions of apoA-I and induce severe hypertriglyceridemia in apoA-I-deficient mice. Biochemistry. 2004 Aug 17; 43(32):10442-57.View Related Profiles. PMID: 15301543.
  7. Chroni A, Liu T, Gorshkova I, Kan HY, Uehara Y, Von Eckardstein A, Zannis VI. The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo. J Biol Chem. 2003 Feb 28; 278(9):6719-30.View Related Profiles. PMID: 12488454.
  8. Gorshkova IN, Liu T, Zannis VI, Atkinson D. Lipid-free structure and stability of apolipoprotein A-I: probing the central region by mutation. Biochemistry. 2002 Aug 20; 41(33):10529-39.View Related Profiles. PMID: 12173940.
  9. Gorshkova IN, Liadaki K, Gursky O, Atkinson D, Zannis VI. Probing the lipid-free structure and stability of apolipoprotein A-I by mutation. Biochemistry. 2000 Dec 26; 39(51):15910-9.View Related Profiles. PMID: 11123918.
  10. Gorshkova IN, Menschikowski M, Jaross W. Alterations in the physiochemical characteristics of low and high density lipoproteins after lipolysis with phospholipase A2. A spin-label study. Biochim Biophys Acta. 1996 Apr 19; 1300(2):103-13. PMID: 8652635.
Showing 10 of 28 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 17 distinct years, with a maximum of 3 publications in 1983 and 1990

YearPublications
19822
19833
19851
19871
19882
19891
19903
19912
19951
19962
20001
20022
20041
20061
20081
20112
20141
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

disease
function
lipids
proteins
structure
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700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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