Cataldo Leone, DMD, DMSc
Professor
Boston University Henry M. Goldman School of Dental Medicine
Dept of Periodontics

DMSc, Harvard University
DMD, University of Pittsburgh



Expertise and interests include:

1) Salivary biochemistry. Saliva is a multifunctional and complex body fluid that exerts host-protective effects. I am interested in how specific salivary proteins can protect individuals from oral infectious diseases. Studies are ongoing attempting to quantify protein levels among subjects and correlate them with salivary microbial profiles.

2) Epithelial cell biology. One of the consequences of periodontal disease is an altered gingival epithelium. I am interested in how inflammation alters epithelial cell behavior, in particular the cell-cell and cell-substrate attachment mechanisms.

3) Clinical diagnosis and treatment of oral diseases. I am interested in understanding the risk factors associated with oral conditions as well as evaluating the results of clinical treatments.

Associate Dean of Academic Affairs
Boston University Henry M. Goldman School of Dental Medicine
Department of Academic Affairs


Professor
Boston University Henry M. Goldman School of Dental Medicine
Department of Molecular & Cell Biology


Mentor for Graduate Medical Students
Boston University School of Medicine, Division of Graduate Medical Sciences




Short-term Training for Minority & Women Dental Students
09/30/1994 - 04/30/2005 (PI)
NIH/National Institute of Dental & Craniofacial Research
5 T35 DE07268 10




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Brugnami F, Caiazzo A, Leone C. Local intraoral autologous bone harvesting for dental implant treatment: alternative sources and criteria of choice. Keio J Med. 2009 Mar; 58(1):24-8. PMID: 19398881.
  2. Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT. Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity. J Bone Miner Res. 2007 Apr; 22(4):560-8.View Related Profiles. PMID: 17243865; PMCID: PMC3109431.
  3. Leone CW, Bokhadhoor H, Kuo D, Desta T, Yang J, Siqueira MF, Amar S, Graves DT. Immunization enhances inflammation and tissue destruction in response to Porphyromonas gingivalis. Infect Immun. 2006 Apr; 74(4):2286-92.View Related Profiles. PMID: 16552059; PMCID: PMC1418897.
  4. Graves DT, Naguib G, Lu H, Leone C, Hsue H, Krall E. Inflammation is more persistent in type 1 diabetic mice. J Dent Res. 2005 Apr; 84(4):324-8.View Related Profiles. PMID: 15790737.
  5. Santana RB, Uzel MI, Gusman H, Gunaydin Y, Jones JA, Leone CW. Morphometric analysis of the furcation anatomy of mandibular molars. J Periodontol. 2004 Jun; 75(6):824-9.View Related Profiles. PMID: 15295948.
  6. Gusman H, Leone C, Helmerhorst EJ, Nunn M, Flora B, Troxler RF, Oppenheim FG. Human salivary gland-specific daily variations in histatin concentrations determined by a novel quantitation technique. Arch Oral Biol. 2004 Jan; 49(1):11-22.View Related Profiles. PMID: 14693192.
  7. He H, Liu R, Desta T, Leone C, Gerstenfeld LC, Graves DT. Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. Endocrinology. 2004 Jan; 145(1):447-52.View Related Profiles. PMID: 14525917.
  8. Leone CW, Oppenheim FG. Physical and chemical aspects of saliva as indicators of risk for dental caries in humans. J Dent Educ. 2001 Oct; 65(10):1054-62.View Related Profiles. PMID: 11699977.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2004

YearPublications
20011
20031
20042
20051
20061
20071
20091
Contact for Mentoring:


100 E. Newton St Goldman SDM
Boston MA 02118
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