Kenneth Walsh, PhD
Aram V. Chobanian Distinguished Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine Section

PhD, University of California, Berkeley



My laboratory examines molecular events that drive cardiovascular cell growth, differentiation and apoptosis. Over the past decade my laboratory has been investigating mechanisms of inter-tissue communication and how these systems contribute to physiological versus pathological tissue growth in the cardiovascular system.

Professor
Boston University School of Medicine
Department of Medicine
Cardiovascular Medicine Section

Director of Whitaker Cardiovascular Institute
Boston University School of Medicine


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Inflammatory Pathways in Aortic Aneurysms
04/01/2016 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL132564-02

Inflammatory Wnt signaling in ischemic myocardium
01/01/2016 - 12/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL131006-02

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL126141-03

Cardio-metabolic actions of FSTL1
03/28/2013 - 09/30/2017 (PI)
Takeda Pharmaceuticals North America, Inc.

Paracrine Regulation of Heart Failure
07/01/2016 - 06/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL116591-04

Myokine Control of Hepatic Steatosis
09/15/2016 - 05/31/2017 (PI)
NIH/National Institute on Aging
1R21AG052160-01A1

Mitochondrial Dynamics and Cardiac Remodeling
06/01/2016 - 05/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL120160-04

Follistatin-like protein 1 in cardiac and systemic metabolism
04/01/2016 - 03/13/2017 (PI)
Temple University of the Commonwealth System of Higher Education NIH NHLBI
1R01HL129120-01A1

Metabolic Control of Endothelial Cell Phenotype
09/30/2005 - 02/28/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5P01HL081587-10

INSL6/GPCR Interaction
03/28/2013 - 09/26/2016 (PI)
Takeda Pharmaceuticals North America, Inc.

Showing 10 of 31 results. Show All Results



Yr Title Project-Sub Proj Pubs
2017 Follistatin-like protein 1 in cardiac and systemic metabolism 5R01HL129120-02
2017 Inflammatory Pathways in Aortic Aneurysms 5R01HL132564-02
2017 Inflammatory Wnt signaling in ischemic myocardium 5R01HL131006-02 4
2017 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-03 4
2016 Myokine Control of Hepatic Steatosis 1R21AG052160-01A1
2016 Follistatin-like protein 1 in cardiac and systemic metabolism 1R01HL129120-01A1
2016 Inflammatory Pathways in Aortic Aneurysms 1R01HL132564-01
2016 Inflammatory Wnt signaling in ischemic myocardium 1R01HL131006-01 4
2016 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-02 4
2016 Mitochondrial dynamics and cardiac remodeling 4R01HL120160-04 6
Showing 10 of 128 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Karki S, Ngo D, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A Regulates Adipose Tissue Angiogenesis via Anti-Angiogenic VEGFA165b in Obese Humans. Am J Physiol Heart Circ Physiol. 2017 Apr 14; ajpheart.00776.2016.View Related Profiles. PMID: 28411232; DOI: 10.1152/ajpheart.00776.2016;.
  2. Wu CL, Satomi Y, Walsh K. RNA-seq and metabolomic analyses of Akt1-mediated muscle growth reveals regulation of regenerative pathways and changes in the muscle secretome. BMC Genomics. 2017 Feb 16; 18(1):181.View Related Profiles. PMID: 28209124; DOI: 10.1186/s12864-017-3548-2;.
  3. Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, Andrés V, Hirschi KK, Martin KA, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017 Feb 24; 355(6327):842-847.View Related Profiles. PMID: 28104796; DOI: 10.1126/science.aag1381;.
  4. Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496.View Related Profiles. PMID: 27688298.
  5. Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. EMBO Mol Med. 2016 08; 8(8):949-66.View Related Profiles. PMID: 27234440; PMCID: PMC4967946; DOI: 10.15252/emmm.201506151;.
  6. Lee RT, Walsh K. The Future of Cardiovascular Regenerative Medicine. Circulation. 2016 Jun 21; 133(25):2618-25. PMID: 27324357; PMCID: PMC4918634; DOI: 10.1161/CIRCULATIONAHA.115.019214;.
  7. Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease. Circ Res. 2016 May 27; 118(11):1786-807.View Related Profiles. PMID: 27230642; PMCID: PMC4887147; DOI: 10.1161/CIRCRESAHA.115.306885;.
  8. Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. PLoS One. 2016; 11(3):e0151515.View Related Profiles. PMID: 26999812; PMCID: PMC4801331; DOI: 10.1371/journal.pone.0151515;.
  9. Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):561-9.View Related Profiles. PMID: 26800561; PMCID: PMC4913891; DOI: 10.1161/ATVBAHA.115.306578;.
  10. Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles. PMID: 26722122; PMCID: PMC4859355; DOI: 10.1161/JAHA.115.002277;.
Showing 10 of 97 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 97 publications over 19 distinct years, with a maximum of 18 publications in 2014

YearPublications
19961
19982
19992
20003
20021
20044
20054
20061
20071
20085
200911
20109
20115
20122
201310
201418
20159
20166
20173
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

apoptosis
cardiovascular system
cell differentiation
cell growth
inter-tissue communication
Contact for Mentoring:


700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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